The present invention relates to roadside analyzer for determination of illegal drugs abuse, including, but not limiting to detection of explosives, toxic industrial chemicals and other banned or regulated compounds, biomarkers and phytochemicals in a sample in situ in at least one
human body fluid sample, specifically in
oral fluid (
saliva), but not limiting to other clinical samples of interest (
urine, blood, exhaled breath,
exhaled breath condensate, etc.) It consists of automatic processor for preparing samples suitable for analysis. Analysis part of the instrument implements three technologies, namely
solid phase extraction prior to analysis,
capillary electrophoresis for separation of analytes from the sample matrix and impedance (contactless
conductivity) or
fluorescence or both impedance (contactless
conductivity) and
fluorescence for detection of analytes of interest.