204 results about "Drug cost" patented technology

A cost estimation tool, preferably a handheld computer, prices and evaluates the financial impact of new residents' prior to admission. Immediate access to this information and built-in therapeutic substitution and clinical advisories provides the opportunity to optimize pharmaceutical regimens prior to admission. In addition, an abbreviated Resource Utilization Group (RUG) evaluation function provides a rapid assessment tool to project reimbursement under the Medicare Prospective Payment System (PPS). A user may enter a complete drug regimen and estimate the costs for the regimen. Similarly, managed care reimbursement from managed care organizations (MCOs) to be analyzed. Also, drug cost may be estimated through a MEDICAID Preferred Drug List database that identifies potential Non-Preferred drugs that may be non-compensable. The present invention further transmits results wirelessly to health care providers.

The invention belongs to the field of medicine and gene engineering, and provides a composition for inhibiting the proliferation of tumor cells. The composition contains epigallocatechin gallate (EGCG) and daunorubicin (DNR), and the mass ratio of the epigallocatechin gallate to the daunorubicin is 600: 1-1: 2. The combination of the EGCG and the DNR, on one hand, ensures that the effect of inhibiting the proliferation of the tumor cells is more obvious than the superposition of single use effects, on the other hand, the combination of the EGCG and the DNR obviously reduces the using amount of the DNR, greatly reduces the cardiac toxicity of the DNR, and strengthens the anti-tumor effect of the DNR at the same time. The EGCG is a natural tea extract, has rich resource and low price, and almost has no toxic side effect after more than one thousand years of drinking, so the combination of the EGCG and the DNR relatively reduces the using amount of the DNR and drug cost. The invention provides a high-efficiency cheap anti-tumor pharmaceutical composition, which improves the inhibition rate of tumor and reduces the treatment cost of tumor patients at the same time.

The invention discloses a method for increasing the oestrus breeding rate of replacement gilts. The method includes the steps of breeding gilt selection, nutrient matching, feed mildewing, illumination control, temperature, humidity and ventilation control, and replacement gilt raising. In the method, vaccine immunity and drug health care should be performed; green fodder should be provided; driving movement, swinery changing, swinery combination and vehicle carrying movement should be performed; oestrus inducing should be performed; recording and short-time high-quality raising should be performed; breeding age in days and weight should be reasonable; concentrated oestrus breeding should be performed. Hormone oestrus promotion, Chinese herbal medicine oestrus promotion, starvation treatment and brown sugar oestrus promotion are performed on the anestrus replacement gilts. According to the invested cost of the method, 5166 replacement gilts are purchased this year, PG 600 needs to be used for 20% of the replacement gilts for oestrus promotion, the cost of the PG 600 used for each replacement gilt is 43 RMB, and the drug cost is 44427.60 RMB; according to the output value, after conventional treatment measures and oestrus promotion of PG 600, the oestrus breeding rate reaches 94.12%. 5166 replacement gilts are introduced, and supposing that the overall oestrus breeding rate is 93%, the standard oestrus breeding rate of the replacement gilts is 90%; the anestrus replacement gilts are sold, and supposing that each replacement gilt is 130 kg and each kg of the replacement gilts is 12 RMB, 411213.60 RMB of loss is reduced.

The invention relates to a fly killing composition which is composed of an original drug component A, an original drug component B and an auxiliary component C, wherein the total weight of the component A and the component B is 0.03-10% of that of a pesticide composition; the original drug component A is fipronil; and the original drug component B is pyrethroid integrating high-efficiency knockout performance and lethal performance. According to the invention, the response speed is obviously increased through high contact toxicity of the pyrethroid; with the help of high-efficiency stomach poisoning action and synergistic action of the fipronil, the killing speed is further accelerated; simultaneously, the lethality is obviously increased; a more efficient drug is provided for controlling vector-borne infection in environments required for residential production and living and for protecting people health; in addition, while obviously increasing the fly killing efficiency, resistance is delayed, and the drug cost is saved.

The invention discloses a pesticide composition containing ethirimol and thiophanate-methyl. The composition comprises common additives, ethirimol and thiophanate-methyl, wherein the weight-part ratio of ethirimol to thiophanate-methyl is 10:1-1:20, and the weight percentage of the total weight of ethirimol and thiophanate-methyl in the pesticide composition is 10 to 90 percent. The additives are one or more of solvents, emulsifiers, wetting agents, stabilizers, dispersants, thickeners, pH regulators, defoamers, antifreeze and filling agents. The pesticide composition with ethirimol and thiophanate-methyl needs to be used before or at an early stage of the occurrence of diseases. The composition has the preventing-controlling effect obviously improved in comparison with that of single agents, and reduces the use dosage of pesticide so as to reduce the influence of the pesticide on environment as well as drug cost. The composition is particularly used to prevent and control powdery mildew of apple trees.

The invention discloses a bactericidal composition containing cupric nonyl phenolsulfonate and a methoxy-acrylate bactericide. The methoxy-acrylate bactericide is selected from azoxystrobin, kresoxim-methyl, metominostrobin, fluoxastrobin, trifloxystrobin, orysastrobin, picoxystrobin, pyraclostrobin, enostrobilurin, SYP-1620, phenylatestrobin, coumoxystrobin, pyraoxystrobin and pyraclostrobin, wherein the weight ratio of the cupric nonyl phenolsulfonate to the methoxy-acrylate bactericide is 1:5-20:1. The bactericidal composition can be prepared into missible oil, microemulsion, water-dispersible granules, wettable powder and a suspending agent which are permitted in the agriculture. The bactericidal composition containing the cupric nonyl phenolsulfonate and the methoxy-acrylate bactericide is reasonable in ingredients, good in bactericidal effect and low in drug cost, and the activity and the bactericidal effect are not formed by the activities of the ingredient simply. Compared with an existing single preparation, the bactericidal composition has remarkable synergistic effect except the remarkable bactericidal effect, is free of pollution to crops and good in safety, meets the safety requirements of pesticide preparations, and has remarkable preventive and control effect on powdery mildew, downy mildew, anthracnose and banded sclerotial blight of the crops.

The invention discloses a desinsection composition containing nitenpyram and imidacloprid. The desinsection composition has higher cooperative synergism and has the characteristics of overcoming and delaying insect drug resistance, preventing spectrum enlargement, high desinsection speed, low drug cost, and the like. The desinsection composition is prepared from nitenpyram, imidacloprid, and proper quantities of pesticide addition agents or carriers, wherein the nitenpyram and the imidacloprid are used as active ingredients, and the weight ratio of the nitenpyram to the imidacloprid is 0.1-40:0.1-40. The desinsection composition can be widely applied to crops such as grain crops, rice, cotton, vegetables, fruit trees, and the like to prevent various injurious insects.

The invention relates to a method for simultaneous determination of the contents of 6 kinds of sedative-hypnotic drugs in serum by a UHPLC-CAD combined technology, wherein the 6 kinds of sedative-hypnotic drugs are diazepam, lorazepam, alprazolam, estazolam, clonazepam and zolpidem tartrate. The method is characterized by including the following steps: 1) reference substance preparation, 2) internal standard solution preparation, 3) sample solution preparation, 4) mobile phase solution preparation, 5) chromatographic condition setting, 6) electrospray detector condition optimization, 7) sample determination, 8) gradient-concentration reference substance solution preparation, 9) standard curve preparation, and 10) data calculation and analysis. The method is advanced, has good clinical application prospects and effects, can rationally use drugs for clinic, increases drug curative effects, lowers toxic and side effects and drug costs, and plays a positive role.

The present invention discloses a corn seed coating agent, and relates to a seed coating agent. The corn seed coating agent is characterized in that: the corn seed coating agent is prepared from the following raw materials, wherein the raw materials comprise 15-25 kg of a film-forming agent, 0.1-0.5 kg of 6BA, 1-5 kg of 1,1-dimethylpiperidinium choride, 40-60 kg of an insecticide and 15-25 kg of a fungicide; during preparing, the film-forming agent is added to the water according to a ratio of the film-forming agent to the water of 1:48-52 to prepare a water agent, then the other raw materials are added to the water agent to carry out uniform mixing to obtain the corn seed coating agent. The insecticide comprises imidacloprid and / or carbosulfan, wherein the weight ratio of the imidacloprid to the carbosulfan is 3-5:1 when the imidacloprid and the carbosulfan are added. The fungicide comprises difenoconazole. Other trace element fertilizer and microelements are added to the raw materials. The corn seed coating agent has the following advantages that: the corn seed coating agent contains the fungicide, the insecticide and the plant growth regulator; with adopting the corn seed coating agent, the seedling disease, the seed-transmitted bacteria, the soil-transmitted bacteria, and other diseases can be removed; the soil insect and the seedling diseases and insect pests can be prevented; the drug cost and the working hours for spraying the drug can be saved; the corn seed coating agent provides the benefit for improvement of the quality of the corn, and the yield of the corn can be generally increased by 15-20%.

The invention discloses a synergistic insecticidal composition containing chlorfluazuron and chlorpyrifos-methyl and the application thereof. The synergistic insecticidal composition uses the chlorfluazuron and the chlorpyrifos-methyl as main active contents, wherein the weight ratio of the chlorfluazuron to the chlorpyrifos-methyl is 0.1-65 to 0.1-80. The insecticidal composition can generate higher synergy, overcome and delay the drug resistance of pests and expand control spectrum, has high insecticidal rate, decreases the drug cost and can be used for preventing resistant lepidoptera withthe effect remarkably higher than the single preparation thereof.

The invention discloses use of dihydroartemisinin in preparation of a drug for inhibition of tumour growth, and the tumour is liver cancer tumor, breast cancer tumor, melanoma or intestinal cancer tumor. The liver cancer tumor is human liver cancer HepG-2, human liver cancer QGY and human liver cancer SMMC. The breast cancer tumor is human breast cancer Bcap-37.The intestinal cancer tumor is human colon carcinoma Colo-205. The drug for inhibition of tumour growth may also include one of artemisinin and artemisinin derivative. The dihydroartemisinin can be used in preparation of the drug for inhibition of tumour growth, and is obvious in anti-cancer effect, small in side effect of chemotherapy, safe to use, and low in drug cost.

The invention discloses application of a boscalid-containing bactericidal composition to prevention and treatment of rot diseases. The composition is prepared from active components including boscalid and triazole fungicide, and an auxiliary agent, wherein the triazole fungicide is selected from one of tebuconazole, flusilazole, epoxiconazole, prothioconazole, propiconazole and hexaconazole; the weight ratio of the boscalid to the triazole fungicide ranges from (40 to 1) to (1 to 40), preferably (20 to 1) to (1 to 20). The composition disclosed by the invention can be prepared into agriculturally acceptable suspension agents, water dispersible granules, paste, ointment, suspension emulsion, dispersible oil suspension emulsion and missible oil. The boscalid-containing bactericidal composition has reasonable components, has good prevention and treatment effects on the rot diseases of fruit trees and can be used for promoting wound healing and reducing the recurrence rate of the rot diseases; compared with an existing single preparation, the boscalid-containing bactericidal composition has remarkable prevention and treatment effects, also has a remarkable synergistic effect, is low in drug cost and good in safety, and meets the safety requirements of pesticide preparations.

The invention discloses an insecticidal composition containing thiacloprid amide and synthetic pyrethroid insecticides, comprising effective active ingredients of thiacloprid amide and one of etofenprox, silafluofen, tefluthrin, high-efficiency cyhalothrin, bifenthrin, high-efficiency cypermethrin and high-efficiency cyfluthrin synthetic pyrethroid insecticides, wherein the weight ratio of the thiacloprid amide to the synthetic pyrethroid insecticide is (1:60)-(60:1). The composition can be prepared into agriculturally acceptable water dispersible granules, wettable powder, suspension agent, dispersible oil suspension agent, micro capsule suspension agent, missible oil or micro emulsion, the invention has the advantages of reasonable components, good insecticidal effect and low drug cost, the activity thereof and insecticidal effect are not simply superimposed by the activities of all the components, compared with the existing single preparation, not only obvious insecticidal effect is realized, but also obvious synergistic effect is realized, production of resistance is reduced and delayed, preparation residue is less, no pollution is produced to crops, and safety is good, thus meeting safety requirements of pesticide preparation. The invention has high control efficiency on rice stem borer, vegetable plutella xylostella, beet armyworm, cotton bollworm and apple olethreutid injurious insects.

The invention provides a method for preparing microbial fermented feed capable of keeping intestinal health of pigs, comprising the following steps: activating the strains of lactobacillus plantarum and the strains of clostridium butyricum; fermenting and cultivating the first liquid, fermenting and cultivating the second liquid, and fermenting and cultivating the third liquid; freezing and drying the solid fermentation culture of the lactobacillus plantarum and the solid fermentation culture of the clostridium butyricum, and mixing to obtain the microbial fermented feed. The invention has good biological function, keeps the micro-ecological balance of the intestinal tract, improves the production volume, saves the drug cost, and greatly improves the pig raising efficiency. The preparation method of the invention is simple and practical, and has large function and good market prospect.

The invention discloses a bactericidal composition containing pyraclostrobin, which comprises a first active ingredient pyraclostrobin and a second active ingredient cyazofamid or phosethyl-aluminium, wherein the weight ratio of the first active ingredient to the second active ingredient is 1:15-10:1. The bactericidal composition can be prepared into water-dispersible granules, wettable powder and a suspending agent which are permitted in the agriculture. The bactericidal composition is reasonable in ingredient, good in bactericidal effect and low in drug cost, and the activity and the bactericidal effect are not formed by the activities of the ingredient simply. Compared with an existing single preparation, the bactericidal composition has the remarkable synergistic effect and good safety to crops besides the remarkable bactericidal effect, meets the safety requirements of pesticide preparations, and has remarkable preventive and treatment effect on downy mildew, epidemic diseases and leaf spot diseases of the crops.

The invention discloses a method for producing spores of clostridium butyricum and application thereof in livestock and poultry rearing, and aims to provide a method for simply and conveniently culturing a large amount of spores of the clostridium butyricum with steady activity in order to solve the problems that a current method for culturing the clostridium butyricum has high cost and high equipment requirement or has long production period and low transformation ratio of the spores, and apply a fermentation culture fluid to the rearing process of livestock and poultry to reduce the diarrhea rate of the livestock and poultry and improve the productivity. The method comprises the following steps of: activating the clostridium butyricum, then inoculating the clostridium butyricum to a culture medium which takes soybean cake powder or corn starch or corn steep liquor as a main raw material, and sealing the culture medium for fermentation culture; and diluting an obtained fermented bacterial liquid by tap water or feed to be between 1*105 and 5*105cfu / g, and directly feeding the fermented bacterial liquid to the livestock and poultry. The method has the advantages of simple and convenient process, low cost, high utilization rate of the spores, rich nutrition of the bacterial liquid, effective reduction in the diarrhea rate of the livestock and poultry and the death rate of newborn livestock and poultry, improvement on the productivity, and drug cost reduction.

The invention relates to a herbicide composition, which comprises the following active components in parts by weight: 1 to 20 parts of cyhalofop-butyl, 1 to 20 parts of metamifop and 1 to 60 parts of quinclorac or salt thereof. The invention also relates to application of the herbicide composition in preventing and controlling annual and perennial broadleaf weeds and gramineous weeds of paddy fields. The herbicide composition has much higher weeding effect compared with a single dose, shows great synergistic effect, reduces the drug amount, lowers the drug cost for farmers and reduces influence on environment; meanwhile, the herbicide composition expands the herbicide control spectrum and effectively delays the occurrence and development of single dose resistance.

The present invention discloses a thymopent aqueous solution preparation, wherein thymopent is adopted as an active component raw material, a pharmaceutical adjuvant and water are added, and mixing is performed to prepare the thymopent aqueous solution preparation, wherein the adjuvant comprises an acetic acid-sodium acetate buffer solution adopted as a pH value adjustment agent, calcium sodium ethylene diaminetetracetate adopted as a protection agent, and sodium chloride adopted as an osmotic pressure adjustment agent, the thymopent amount is 0.1-100 mg / ml, the acetic acid-sodium acetate buffer solution amount is 1.5-1500 mg / ml, the calcium sodium ethylene diaminetetracetate amount is 0.1-40 mg / ml, and the sodium chloride amount is 0.3-300 mg / ml. The thymopent aqueous solution preparation has characteristics of stable low temperature long-time storage, stable room temperature storage, and stability under a strong illumination condition, and does not generate significant change after storing for 5 days at a high temperature of 60 DEG C so as to reduce transportation requirements, provide convenience for drug transportation, substantially reduce a drug cost, and timely provide drug requirements for patients.

The invention discloses a carbon ion radiotherapy method established based on an individualized tumor tissue relative biological effectiveness determined by a patient-derived tumor tissue xenograft transplantation model. For an individual patient, the values of the individualized tumor tissue relative biological effectiveness are obtained by the patient-derived tumor tissue xenograft transplantation animal model, and a process and method of the carbon ion radiotherapy are established. According to the invention, a precise individualized treatment scheme of cancer patients can be given, due tothe individualized precise medical treatment, the treatment accuracy can be improved, and the side effects caused by the treatment of a patient can be effectively reduced, so that the damage to the patient can be reduced, and the medical quality can be well ensured, the treatment effect is improved, the patient is benefited, and the device is easier to popularize and use. According to the invention, the indirect economic loss caused by the disease due to treatment can be reduced, more targeted individualized and accurate carbon ion treatment is provided for the patient through a prediction means, and unnecessary recovery drug cost is avoided.

The invention discloses a Moringa leaf compressed tablet and a preparation method thereof. The raw materials are as follows in weight percentage: 50-80% of Moringa leaf powder, 10-45% of crystal cellulose, 1-5% of magnesium stearate, wood Sugar alcohol 0.2-2.5%, ascorbic acid 0.2-2.5%, mix the raw materials evenly, perform dry compression, and then use polyethylene glycol alcohol solution 0.3-0.7% for coating, testing and packaging. The Moringa leaf compressed tablet prepared by the formula of the present invention has quick dissolution of the active ingredients of the Moringa leaf and high bioavailability, can better exert the drug effect of active molecules of the Moringa leaf and reduce the cost of medication. The present invention has good effects on hypertension, hyperlipidemia, diabetes, gout, etc.; it can also help to improve and prevent diseases, improve sleep, enhance memory, delay aging, and can also be used to treat diseases in special parts such as liver, spleen, and meridian .

The invention discloses a pesticide composition containing emamectin benzoate and cidial. The invention is characterized in that the composition is missible oil, wettable powder, emulsion in water or granules prepared by taking emamectin benzoate and cidial as active ingredients and solvent, a carrier, surfactant and accessories as assisting agents, wherein the weight percent of the active ingredients is 10.1-60%. The composition has reasonable matching, enhances quick acting effect, reduces drug cost, produces less damage and pollution to the ecological environment and is beneficial to safety protection of man and beast, thus being a blended preparation which has high efficiency and low toxicity and preventing injurious insets from producing drug resistance.

The invention discloses a curcumin solid dispersion and a preparation method and application thereof. The curcumin solid dispersion comprises the following components (by weight): the ratio of curcumin raw material: water-soluble carrier: solubilizer: flavoring agent is 2:2-8:6-15:1-2. The components of the curcumin solid dispersion are thoroughly mixed according to a specific suitable sequence and process; and combined with a fluidized bed spray granulation method, particles are more uniform, and the drug and carrier ingredients are more fully combined. The curcumin of the obtained product has outstanding solubility. The pharmacokinetic test in pigs shows that peak concentration is significantly improved, the bioavailability is significantly higher than bioavailability of a common preparation, and the curative effect of curcumin in clinical application is raised. The dosage is reduced, and palatability is good. The preparation process is simple but not cumbersome; energy consumption is low; drug cost is reduced; dust and static electricity are avoided; and the preparation process is easy for industrial mass production.

The invention provides a busulfan injection which is simple in prescription and stable in quality. The injection is prepared by the followings method: (1), dissolving busulfan into a mixed solvent of N, N-dimethyl acetamide and polyethylene glycol 400 in a volume ratio of (17-57):(83-43) to obtain a busulfan solution with concentration of 1mg / mL-7.5mg / mL; and (2), filtering and filling in a sterile manner, wherein in the dissolving process of the step (1), the temperature of the solution is 4 DEG C-25 DEG C, or / and inert gases are charged in an operation process until the solution is saturated. Not only is stability of the busulfan injection obtained by the preparation method disclosed by the invention improved, but also the safety of the injection after long-time storage is effectively ensured. Meanwhile, other substances or other chemical components are not introduced in the preparation process, so that the medication safety is ensured, and the drug cost is also lowered.

The invention relates to the technical field of big data, and discloses an online inquiry medicine opening system, which is used for improving the iteration efficiency of the online inquiry medicine opening system. The online inquiry medicine opening system comprises a hospital guide system, an inquiry system, an ordering system, a direct accounting system, a payment system and a customization system. The hospital guide system is used for recommending a corresponding doctor online inquiry page; the inquiry system is used for carrying out online inquiry in the displayed doctor online inquiry page to obtain electronic prescription information; the ordering system is used for generating medicine order information according to the electronic prescription information; the direct accounting system is used for deducting prescription amount information according to the drug order information and the corresponding drug cost direct settlement rule information to obtain user self-payment amount information; the payment system is used for paying the self-payment amount information of the user; and the customization system is used for performing function customization on each system. In addition, the invention also relates to a blockchain technology, and the electronic prescription information can be stored in the blockchain node.

The embodiment of the invention discloses a drug cost standard exceeding early warning method and device based on data processing. The method comprises the following steps that a prescription of drugsin a to-be-monitored medical unit is obtained; drug information of the prescription is obtained, average daily drug cost of the to-be-monitored medical unit is determined based on the drug information; whether the average daily drug cost is greater than or equal to the threshold value of the corresponding average daily drug cost of the to-be-monitored medical unit is determined; and if the average daily drug cost is greater than or equal to the threshold value of the average daily drug cost, drug cost standard exceeding early warning information is sent to the to-be-monitored medical unit. Timeliness of drug use monitoring in medical units can be improved, reliability of drug use monitoring in the medical units can be improved, effective medical resource utilization rate is improved, andapplicability is high.

An embodiment of the application discloses a traditional Chinese medicine prescription drug expense exceeding warning method and device based on data processing. The method herein includes: acquiringtraditional Chinese medicine prescriptions of a medical unit to be supervised; acquiring drug information of each type of traditional Chinese medicine decoction pieces in the traditional Chinese medicine prescriptions, and determining daily average single-prescription drug expense of the medical unit to be supervised according to the drug information of the various types of traditional Chinese medicine decoction pieces; acquiring traditional Chinese medicine decoction piece information of each of the various types of traditional Chinese medicine decoction pieces, and determining daily averagesingle-prescription single-drug expense of the various types of traditional Chinese medicine decoction pieces according to the traditional Chinese medicine decoction piece information of the various types of traditional Chinese medicine decoction pieces; determining whether the daily average single-prescription drug expense and the daily average single-prescription single-drug expense of the various types of traditional Chinese medicine decoction pieces are greater than or equal to medication index parameter thresholds of the medical unit to be supervised; if yes, sending a warning informationabout traditional Chinese medicine decoction pieces expense exceeding. The traditional Chinese medicine prescription drug expense exceeding warning method and device based on data processing help improve the accuracy of medication supervision for Chinese medicine decoction pieces in medical units, drug cost controllable is improved for the medical units, and the method and device are highly applicable.

The invention belongs to a herbicide for preventing and weeding dicotyledon weeds and barnyard grasses in paddy fields, relating to a mixed herbicide which has the effective active components of carfentrazone-ethyl, pyrazosulfuron-ethyl and quinclorac. The mixed herbicide comprises the effective active components, moist additive, filler and the like, and is characterized in that the effective active components are the carfentrazone-ethyl, the pyrazosulfuron-ethyl, the quinclorac, preparations with different contents thereof and various dosage forms, wherein the carfentrazone-ethyl, the pyrazosulfuron-ethyl and the quinclorac have the ratio by weight of 1:(1-2.5):(15-40). The invention has the advantages that after being mixed, the carfentrazone-ethyl, the pyrazosulfuron-ethyl and the quinclorac have obvious effects of synergism and enhancing weed control speed, obtains control effect to various broadleaf weeds and the barnyard grasses in the paddy fields, has low toxicity and low residual, expands the weed control spectrum, greatly lowers the drug dosage, the pesticide application frequency and the drug cost, and is beneficial to retarding the succession velocity of weed populations and prolonging the service life of the herbicide.

The invention belongs to the technical field of pesticides, and particularly relates to a sugarcane pesticide and a production method of the sugarcane pesticide. The sugarcane pesticide is characterized by comprising raw materials which are 50 % to 80 % of monosultap, 5 % to 10 % of imidacloprid and auxiliaries, the raw materials are stirred and mixed and are processed through air flow smashing and mixing, and wettable powder is obtained. The sugarcane pesticide has the two functions of the fast-acting property and the long residual action at the same time, can prevent sugarcane borers and woolly aphids at the same time, is multifunctional, reduces sugarcane drug costs, is low in toxicity and little in small, and accords with pesticide standard rates.

The invention discloses a composite herbicide formulated by 0.5-1.5 portion of pyrazosulfuron-ethyl, an active component, and 7.5-8.5 portion of prometryne according to weight account, which can effectively control weed such as Chinese water chestnut and pondweed, with a herbicidal rate of above 80 per cent. Through measurement of indoor biology, co-toxicity coefficient of the herbicide of the invention is bigger than 100; two single-doses has synergistic interaction effect; dosage for single using the pyrazosulfuron-ethyl is decreased and drug cost is reduce. By field plot experiment, the herbicide of the invention has a stable weeding effect and is safe for growth of rice.