19 results about "Alternative therapy" patented technology

A method of determining the likelihood that a subject with cancer will respond to an immunotherapy comprising a checkpoint inhibitor. The method comprises detecting the level of histamine in a biological sample obtained from the subject. Subjects determined to have a low likelihood of responding to the immunotherapy can be administered an alternative therapy or administered an antihistamine in conjunction with the immunotherapy. Methods of treating cancer patients are also provided, as are kits and systems for histamine detection, recordation, and responder status determination.

The present invention provides a novel use and methods comprising antibodies, or antigen-binding fragments thereof, which bind to a CCR7 receptor for use as a novel therapeutic agent in prevention and / or treatment of graft versus host disease (GVHD), preferably in hematopoietic stem cell transplantation (HSCT), more preferably allogeneic hematopoietic stem cell transplantation. GVHD of the invention can be acute (aGVHD) and / or chronic (cGVHD), preferably acute. The antibodies and antigen-binding fragments are capable of selectively depleting ex vivo or in vitro immune cells expressing CCR7 and are capable in vivo of selectively killing immune cells expressing a CCR7 receptor and of impairing / blocking migration and of activation of said immune cells, which are involved in the development and evolution of GVHD. The use of said antibodies for depleting, killing and impairing / blocking migration and activation of immune cells expressing CCR7 cells is disclosed, thus providing an alternative therapy for preventing and treating GVHD in both acute and chronic types.

The invention relates to application of a moxibustion transdermal component citral in regulation and control of synovial fibroblast-like cell (FLS) proliferation and inflammatory factor secretion, and belongs to the technical field of medicines. In the background technology, rheumatoid arthritis (RA) treatment depends on drugs, but has the defects of great side effects, easy recurrence and the like. It is found through experiments that within the concentration range of 0.131-13.1 [mu] M, citral can effectively inhibit FLS proliferation and regulate secretion of inflammatory factors IL-6 and TNF-alpha. The invention provides a safe and effective replacement therapy, and citral is used for regulating and controlling the FLS function so as to control the progress of RA disease and improve the joint function and life quality of a patient. The method has the advantages of high safety, low cost, multi-target effect and remarkable innovativeness and practicability.

Embodiments of the present invention provide methods, systems, devices, and software for providing customized, clinically relevant designs, such as treatment plans / solutions for at least a single tooth replacement therapy, on demand and in real time, enabling immediate confirmation of the effectiveness and implementation of the patient-specific treatment solution. A machine learning algorithm is used in a computer-implemented method or system for automated restoration design. The restoration design includes the design of restorative elements such as crowns and abutments. Software for performing the method when executed on a digital processor is provided. The method also includes fabrication of the restorative elements.

This invention discloses a traditional Chinese medicine composition comprising Codonopsis pilosula, Atractylodes macrocephala, Poria cocos, Glycyrrhiza uralensis (processed), Citrus reticulata peel, Torreya grandis, Citrus medica, Rosa rugosa, Hippophae rhamnoides, Kaempferia galanga, and Amomum tsao-ko. This composition is specifically designed for individuals requiring improved digestive function, aiming to address indigestion caused by factors such as irregular eating habits and excessive physical activity. This invention utilizes the synergistic effects of multiple traditional Chinese medicinal herbs to not only enhance digestive capacity but also improve the body's immune function. The efficacy and safety of this composition were demonstrated through tests on the general survival status, small intestinal propulsion rate, gastric emptying rate, gastrointestinal hormone levels, and immunoglobulin levels in rats. Therefore, this traditional Chinese medicine composition can serve as a novel treatment option, providing a natural, safe, and effective alternative therapy for patients with digestive disorders; it is also suitable as a daily health supplement to help maintain a healthy digestive system and strong immunity.

A system for generating a medical fluid for renal replacement therapy is operated by a control device according to a method. In the method, a first pump is operated to convey a first fluid from a first container, arranged on a first scale, into a supply path, and a second pump is operated to convey a second fluid from a second container, arranged on a second scale, into the supply path, to generate a mixture therein. The speed of at least one of the pumps is adjusted until a sensor measures a target value of a composition-related parameter. A relation between weight changes of the first and second scales is determined while the sensor measures the target value. The medical fluid is then generated in the supply path, by the pumps being operated, based on signals from the scales, to achieve said relation.

A virtual assistant / chatbot to improve clinical workflow for home renal replacement therapies is disclosed herein. A virtual assistant / chatbot includes a patient-facing user interface configured to enable a patient to engage in a virtual chat session by typing, speaking, or otherwise providing information regarding a patient request or issue related to their renal replacement therapy. The virtual assistant / chatbot also includes a backend server-based system configured to provide logic to respond to a patient's requests. The logic defines a sequence of questions and answers for resolving patient queries. The sequence of assistant / chatbot questions and patient answers may be configured in a node arrangement such that certain patient answers / requests lead to additional questions for additional information from a patient. The virtual assistant / chatbot is configured to answer patient requests automatically or determine if the patient request is to be immediately addressed by a clinician or later through a phone call, text, or email communication.

Current Type 2 Diabetes Mellitus treatments include life-style management, pharmaceuticals and may include bariatric surgery for the morbidly obese. However, issues with compliance, side effects and permanent anatomical alterations provide a need for an alternative therapy to modulate a peripheral nerve, such as the vagus nerve, in a manner that causes a plastic change in the glycemic regulatory system, with or without the involvement of the central nervous system (CNS), that changes the activity of an organ and thereby changing the activity of that organ. Low energy vagus nerve neuromodulation has potential as a new treatment for type 2 diabetes mellitus by inducing plasticity of the body's glycemic regulatory system with low energy transient stimulation. This will allow for effective use of a small implantable pulse generator that requires infrequent, or no, charging during the life of the device.

Featured are methods, peripheral devices, and systems containing the same for use in determining the likelihood of success of pelvic floor treatment therapy. The method may include performing a treatment regimen that includes pelvic floor exercises and monitoring treatment efficacy to determine the likelihood of treatment success in order to continue treatment or employ an alternative therapy.

A virtual assistant / chatbot to improve clinical workflow for home renal replacement therapies is disclosed herein. A virtual assistant / chatbot includes a user interface configured to enable a patient to engage in a virtual chat session by typing, speaking, or otherwise providing information regarding a patient request or issue related to their renal replacement therapy. The virtual assistant / chatbot also includes a server configured to provide logic to respond to the patient's requests. The logic defines a sequence of questions and answers for resolving patient queries. The sequence of assistant / chatbot questions and patient answers may be configured in a node arrangement such that certain patient answers / requests lead to additional questions for additional information from a patient. The virtual assistant / chatbot is configured to answer patient requests automatically or determine when the patient request is to be immediately addressed by a clinician or later through a phone call, text, or email communication.

A virtual assistant / chatbot to improve clinical workflow for home renal replacement therapies is disclosed herein. A virtual assistant / chatbot includes a user interface configured to enable a patient to engage in a virtual chat session by typing, speaking, or otherwise providing information regarding a patient request or issue related to their renal replacement therapy. The virtual assistant / chatbot also includes a server configured to provide logic to respond to the patient's requests. The logic defines a sequence of questions and answers for resolving patient queries. The sequence of assistant / chatbot questions and patient answers may be configured in a node arrangement such that certain patient answers / requests lead to additional questions for additional information from a patient. The virtual assistant / chatbot is configured to answer patient requests automatically or determine when the patient request is to be immediately addressed by a clinician or later through a phone call, text, or email communication.

The aim is to provide technology that improves the precision of treatments in alternative medicine. [Solution] A treatment support system that supports treatment as alternative medicine for a person receiving treatment, comprising: a reaction acquisition unit that acquires reaction information showing the person receiving treatment's response to the practitioner's actions; an analysis unit that analyzes the reaction information using AI including a machine learning model to identify at least one of the affected area and the cause of the affected area; and an output unit that outputs the analysis results from the analysis unit.

Computer implemented methods, systems, and computer readable medium are provided for performing causal inference analyses to determine the more effective treatment among alternative treatments in the healthcare setting using real world observational data. Both binary treatment and adaptive treatment strategies are considered in the analysis. The methods comprise generating a Bayesian marginal structural model and performing a single step of Bayesian regression that incorporates matching, weighting, and estimation processes and in which the matching process is performed using a Guassian process (“GP”) prior covariance function.

To provide alternative treatments for subjects suffering from diseases, disorders, and conditions related to the oxalate pathway. [Solution] The present invention relates to a double-stranded ribonucleic acid (dsRNA) composition that targets the LDHA gene, a method for inhibiting LDHA expression, a method for inhibiting LDHA and HAO1 using such a dsRNA composition, and a method for treating subjects who may benefit from reduced LDHA expression, for example, subjects suffering from diseases, disorders or conditions related to the oxalate pathway.

A method for recommending therapy includes identifying a group of one or more individuals that have stopped using or have not started using a respiratory therapy device, collecting data associated with each of the one or more individuals, and, for each respective individual, determining whether to recommend an alternative therapy based on the data associated with the respective individual. A method for monitoring an individual who is using a mandibular repositioning device (MRD) includes receiving data associated with the individual during a period of time where the individual used the MRD during one or more sleep sessions, analyzing the data to determine a readiness of the individual to transition from the use of the MRD to an alternative therapy, and based on the analysis, transmitting a recommendation to the individual to (i) transition to the alternative therapy and discontinue using the MRD, or (ii) continue using the MRD.

The invention in general relates to the use of probiotics for the management of functional gastrointestinal disorders. More specifically, the present invention relates to the use of Bacillus coagulans or Bacillus subtilis or a combination of both strains for the prevention or treatment of functional gastrointestinal disorders, such as for example functional dyspepsia. The present invention also discloses the use of Bacillus coagulans or Bacillus subtilis or a combination of both strains as alternative therapy or adjunct therapy for or gastric acid suppression treatment.

The invention discloses a traditional Chinese medicine composition which is prepared from radix pseudostellariae, bighead atractylodes rhizome, poria cocos, honey-fried licorice root, pericarpium citri reticulatae, semen torreya, citron, roxburgh rose, sea-buckthorn, rhizoma kaempferiae and amomum tsao-ko. The composition is especially designed for people who need to promote the digestive function, and aims to solve the problem of dyspepsia caused by factors such as diet loss, exercise qi consumption and the like. By utilizing the synergistic effect of various traditional Chinese medicinal materials, the digestion ability is enhanced, and the immune function of the body is also improved. The effectiveness and the safety of the composition are proved by detecting the general survival condition, the small intestine propulsion rate, the gastric emptying rate, the gastrointestinal hormone level and the immune globulin of rats. Therefore, the traditional Chinese medicine composition disclosed by the invention can be used as a new treatment choice, and a natural, safe and effective alternative therapy is provided for patients with digestive dysfunction; the beverage is also suitable for being used as a daily health-care beverage, and helps to maintain a healthy digestive system and strong immunity.

A green light osteoporosis treatment device is provided. The device comprises a light irradiation chamber (1) (dimensions: 105 cm x 80 cm), multiple green LED light sources (with an emission wavelength of 520-525 nm) arranged within the chamber, and a light source control module (characterized by the module being able to adjust the illuminance of the LED light source to 400 lx). The green light with a wavelength of 520-525 nm and an illuminance of 400 lx is scientifically compatible with the GnIH hormone control mechanism, effectively suppressing osteoclast activity and preventing bone loss from the upstream stage. Compared to conventional drug therapy or electromagnetic therapy, this therapy has no chemical side effects and avoids the potential risks associated with hormone replacement therapy (HRT).