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9 results about "Alternative therapy" patented technology

The use of anti-CCR7 mAbs for the prevention or treatment of graft-versus-host disease (GvHD)

PendingAU2019400775B2AntigenAntigen Binding Fragment
The present invention provides a novel use and methods comprising antibodies, or antigen-binding fragments thereof, which bind to a CCR7 receptor for use as a novel therapeutic agent in prevention and / or treatment of graft versus host disease (GVHD), preferably in hematopoietic stem cell transplantation (HSCT), more preferably allogeneic hematopoietic stem cell transplantation. GVHD of the invention can be acute (aGVHD) and / or chronic (cGVHD), preferably acute. The antibodies and antigen-binding fragments are capable of selectively depleting ex vivo or in vitro immune cells expressing CCR7 and are capable in vivo of selectively killing immune cells expressing a CCR7 receptor and of impairing / blocking migration and of activation of said immune cells, which are involved in the development and evolution of GVHD. The use of said antibodies for depleting, killing and impairing / blocking migration and activation of immune cells expressing CCR7 cells is disclosed, thus providing an alternative therapy for preventing and treating GVHD in both acute and chronic types.
Owner:CATAPULT THERAPEUTICS BV +1

A medicinal and edible Chinese medicine composition and a beverage and application thereof in improving indigestion and enhancing immunity

This invention discloses a traditional Chinese medicine composition comprising Codonopsis pilosula, Atractylodes macrocephala, Poria cocos, Glycyrrhiza uralensis (processed), Citrus reticulata peel, Torreya grandis, Citrus medica, Rosa rugosa, Hippophae rhamnoides, Kaempferia galanga, and Amomum tsao-ko. This composition is specifically designed for individuals requiring improved digestive function, aiming to address indigestion caused by factors such as irregular eating habits and excessive physical activity. This invention utilizes the synergistic effects of multiple traditional Chinese medicinal herbs to not only enhance digestive capacity but also improve the body's immune function. The efficacy and safety of this composition were demonstrated through tests on the general survival status, small intestinal propulsion rate, gastric emptying rate, gastrointestinal hormone levels, and immunoglobulin levels in rats. Therefore, this traditional Chinese medicine composition can serve as a novel treatment option, providing a natural, safe, and effective alternative therapy for patients with digestive disorders; it is also suitable as a daily health supplement to help maintain a healthy digestive system and strong immunity.
Owner:GUANGDONG PHARMA UNIV +1

Virtual assistant / chatbot to improve clinical workflows for home renal replacement therapies

A virtual assistant / chatbot to improve clinical workflow for home renal replacement therapies is disclosed herein. A virtual assistant / chatbot includes a patient-facing user interface configured to enable a patient to engage in a virtual chat session by typing, speaking, or otherwise providing information regarding a patient request or issue related to their renal replacement therapy. The virtual assistant / chatbot also includes a backend server-based system configured to provide logic to respond to a patient's requests. The logic defines a sequence of questions and answers for resolving patient queries. The sequence of assistant / chatbot questions and patient answers may be configured in a node arrangement such that certain patient answers / requests lead to additional questions for additional information from a patient. The virtual assistant / chatbot is configured to answer patient requests automatically or determine if the patient request is to be immediately addressed by a clinician or later through a phone call, text, or email communication.
Owner:BAXTER INT INC +1

Neuromodulation system to induce changes in glycemic regulatory system plasticity

Current Type 2 Diabetes Mellitus treatments include life-style management, pharmaceuticals and may include bariatric surgery for the morbidly obese. However, issues with compliance, side effects and permanent anatomical alterations provide a need for an alternative therapy to modulate a peripheral nerve, such as the vagus nerve, in a manner that causes a plastic change in the glycemic regulatory system, with or without the involvement of the central nervous system (CNS), that changes the activity of an organ and thereby changing the activity of that organ. Low energy vagus nerve neuromodulation has potential as a new treatment for type 2 diabetes mellitus by inducing plasticity of the body's glycemic regulatory system with low energy transient stimulation. This will allow for effective use of a small implantable pulse generator that requires infrequent, or no, charging during the life of the device.
Owner:RESHAPE LIFESCIENCES INC

Virtual assistant / chatbot to improve clinical workflows for home renal replacement therapies

PendingUS20260024629A1TherapiesSpeech recognitionPatient requestQuestions and answers
A virtual assistant / chatbot to improve clinical workflow for home renal replacement therapies is disclosed herein. A virtual assistant / chatbot includes a user interface configured to enable a patient to engage in a virtual chat session by typing, speaking, or otherwise providing information regarding a patient request or issue related to their renal replacement therapy. The virtual assistant / chatbot also includes a server configured to provide logic to respond to the patient's requests. The logic defines a sequence of questions and answers for resolving patient queries. The sequence of assistant / chatbot questions and patient answers may be configured in a node arrangement such that certain patient answers / requests lead to additional questions for additional information from a patient. The virtual assistant / chatbot is configured to answer patient requests automatically or determine when the patient request is to be immediately addressed by a clinician or later through a phone call, text, or email communication.
Owner:BAXTER INT INC +1

Treatment support system and treatment support method

The aim is to provide technology that improves the precision of treatments in alternative medicine. [Solution] A treatment support system that supports treatment as alternative medicine for a person receiving treatment, comprising: a reaction acquisition unit that acquires reaction information showing the person receiving treatment's response to the practitioner's actions; an analysis unit that analyzes the reaction information using AI including a machine learning model to identify at least one of the affected area and the cause of the affected area; and an output unit that outputs the analysis results from the analysis unit.
Owner:KABUSHIKI KAISYA LEBEN

Bayesian causal inference models for healthcare treatment using real world patient data

ActiveUS12444507B2Mathematical modelsMedical data miningAlternative treatmentPatient data
Computer implemented methods, systems, and computer readable medium are provided for performing causal inference analyses to determine the more effective treatment among alternative treatments in the healthcare setting using real world observational data. Both binary treatment and adaptive treatment strategies are considered in the analysis. The methods comprise generating a Bayesian marginal structural model and performing a single step of Bayesian regression that incorporates matching, weighting, and estimation processes and in which the matching process is performed using a Guassian process (“GP”) prior covariance function.
Owner:CHILDRENS HOSPITAL MEDICAL CENT CINCINNATI

Lactate dehydrogenase A(LDHA)iRNA composition and method of use thereof

PendingJP2026062630AOrganic active ingredientsGenetic material ingredientsDiseaseAlternative treatment
To provide alternative treatments for subjects suffering from diseases, disorders, and conditions related to the oxalate pathway. [Solution] The present invention relates to a double-stranded ribonucleic acid (dsRNA) composition that targets the LDHA gene, a method for inhibiting LDHA expression, a method for inhibiting LDHA and HAO1 using such a dsRNA composition, and a method for treating subjects who may benefit from reduced LDHA expression, for example, subjects suffering from diseases, disorders or conditions related to the oxalate pathway.
Owner:ALNYLAM PHARMACEUTICALS INC +1

Systems and methods for analyzing use of a mandibular repositioning device

A method for recommending therapy includes identifying a group of one or more individuals that have stopped using or have not started using a respiratory therapy device, collecting data associated with each of the one or more individuals, and, for each respective individual, determining whether to recommend an alternative therapy based on the data associated with the respective individual. A method for monitoring an individual who is using a mandibular repositioning device (MRD) includes receiving data associated with the individual during a period of time where the individual used the MRD during one or more sleep sessions, analyzing the data to determine a readiness of the individual to transition from the use of the MRD to an alternative therapy, and based on the analysis, transmitting a recommendation to the individual to (i) transition to the alternative therapy and discontinue using the MRD, or (ii) continue using the MRD.
Owner:RESMED PTY LTD