349results about How to "Improve inflammation" patented technology

Selective antagonists of A2A adenosine receptors are provided. The novel A2A blockers are useful for the treatment of Parkinson's disease and other diseases.

The disclosure relates to the process of enhanced recovery from injury or body fatigue due to strenuous activity or strenuous conditions using a contemplated apparatus. Generally the apparatuses disclosed utilize two or more physiological properties and / or body interfaces selected from 1) thermoregulation enhancer via cooling or heating sources; 2) blood flow viscosity enhancer via electromagnetic forces; 3) a circulatory pull by creating a negative pressure or vacuum environment which draws more blood to the treatment area; 4) muscle release apparatus via pressure point applicators and / or electric stimulation devices, which enhance the bodies natural abilities to recover from stress, fatigue or injury; and 5) a fatigue stimulator may be utilized to accelerate the amount of inflammation, stress, and / or fatigue applied to an area of the body via a restrictive cuff which prevent the body from constantly experiencing enhanced recovery techniques and depriving the body of natural adaptation.

The invention belongs to the technical field of cosmetics, and in particular relates to a moisturizing essence lotion and a preparation method of the moisturizing essence lotion. The moisturizing essence lotion is prepared from the following components in percentage by weight: 0.00003%-25.5% of sodium hyaluronate, 0.00001%-20% of sodium acetylated hyaluronate, 0.00001%-20% of hydrolyzed hyaluronic acid, 0.001%-1% of a thickener, 0.5%-40% of a moisturizer, 0.1%-30% of a skin efficacy agent, and the balance of deionized water. The essence lotion provided by the invention can regulate the cell viability of the skin essentially, so as to achieve the effects of whitening the skin, resisting wrinkles and resisting skin aging, especially, for the inflammatory skin such as pimple and acne, the moisturizing essence lotion can inhibit the activity of bacteria on the surface of the skin, so that the inflammation can be alleviated.

Device and method for non-invasively monitoring asthma and other respiratory diseases, as well as non-respiratory diseases. The method includes collecting condensate from a subject's breath, testing the condensate to determine its acetic acid / acetate level or concentration, and evaluating these properties to determine the presence, absence or status of a respiratory or non-respiratory disease in the subject. The method may also include, prior to the testing step, standardizing the volatile substances that may be present within the condensate in a degassing or gas standardizing step. The device includes a mouthpiece apparatus configured to receive breath from a subject, a condensation apparatus to condense the subject's breath and produce a condensate, and a collection apparatus having a collection chamber containing means for testing the condensate to determine the acetic acid and / or acetate concentration. The device may also include a system for removing or standardizing the volatile substances that may be present with the condensate. The device and method may be utilized without condensing a subject's breath and collecting the same.

Aspects of the present invention relate to NF-HEV nuclear factor genes and polypeptides. Other aspects related to the use of NF-HEV nuclear factor genes and polypeptides. Other aspects related to the use of NF-HEV nuclear factor polynucleotides and polypeptides expressed in endothelial cells from chronically inflamed tissues, particularly in high endothelial venules endothelial cells (HEVECs) and endothelial cells from HEV-like vessels and small blood vessels, in connection with rheumatoid arthritis and Crohn's disease. Aspects of the invention also relates to drug screening assays for identifying compounds capable of modulating NF-HEV activity, wherein such compounds can be used in inhibiting or preventing chronic inflammation.

Methods and apparatus for the treatment of venous insufficiency, such as varicose veins, are described herein utilizing endovenous treatments. Such treatments may include systems to create an initial endovascular injury to the vessel wall utilizing any number of mechanisms, such as chemical, mechanical, electrical, etc. modalities. An implantable device, optionally having a sclerosing agent infused therein, may additionally be implanted along the injured tissue to promote, maintain, and otherwise enhance the tissue inflammation and scarring, thereby remodeling the diseased vessel wall.

An electrosurgical method for treating chronic wound tissue, comprising: positioning an active electrode in close proximity to the chronic wound, the active electrode being disposed on a distal end of an electrosurgical shaft; applying a high-frequency voltage potential difference across the active electrode and a return electrode sufficient to develop a high electric field intensity associated with a vapor layer proximate the active electrode and in close proximity to the wound tissue; and stimulating an expression of at least one healing mediator.

A method is provided herein to increase an immune response to an antigen. The method includes administering an agent that inhibits extracellular adenosine or inhibits adenosine receptors. Also disclosed are methods to increase the efficacy of a vaccine and to increase an immune response to a tumor antigen or immune cell-mediated tumor destruction.

There is provided the use of a methylxanthine derivative such as theophylline and a steroid in a synergistic combination for the treatment of chronic obstructive pulmonary disease, wherein the combination is administered by the inhaled route for pulmonary delivery.

A method of preparing a target hard body tissue, such as osseous or dental tissue, to receive an implant component including; positioning an active electrode in proximity to a target tissue and proximate an electrically conductive fluid, followed by applying a high frequency voltage between the active electrode and a return electrode, the high frequency voltage sufficient to form a plasma. This plasma modifies at least a portion of the target tissue. An implant component may then be placed adjacent at least a portion of the modified target tissue.

The invention discloses a medicinal composition for treating gynecological inflammation, and belongs to the field of Chinese medicament. The medicinal composition consists of collagen and / or Chinese medicaments for releasing toxin and sterilizing such as collagen and lizardtail, glabrous greenbrier rhizome, Vietnamese sophora root and the like which are prepared into a plurality of dosage forms bycombining the prior art, and is mainly used for treating vaginitis, pelvic inflammation, urethritis and cervicitis diseases. The technical scheme overcomes the defects that the prior externally-applied preparations such as lotion, gel, suppository, ointment and the like have extremely slow response, longer disease course, repeated outbreak and the like, and creatively combines and applies the collagen and the Chinese medicament, can accelerate the healing of ulcer and erosion faces caused by the inflammation, and can greatly shorten the required time for tissue repair.

Intravenous, or indwelling, or integratedmulti-functional devices and systems reduce levels of a targeted compound in blood by selective adsorption. The devices and systems can be used, e.g., to reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices and systems are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices and systems serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.

An electrosurgical method for sterilizing chronic wound tissue, comprising: positioning an active electrode in proximity to the chronic wound tissue; delivering an electrically conductive fluid proximate the active electrode; and applying a high frequency voltage between the active electrode and a return electrode in the presence of the electrically conductive liquid sufficient to generate an ionized vapor layer at the active electrode, wherein the ionized vapor layer sterilizes at least a portion of the chronic wound tissue.

An automatic stage allows rapid and more precise needle placement for radiation therapy using implantable radioactive seeds.

A method to treat cancer uses ultrapheresis, refined to remove compounds of less than 120,000 daltons molecular weight, followed by administration of replacement fluid, to stimulate the patient's immune system to attack solid tumors. In the preferred embodiment, the patient is ultrapheresed using a capillary tube ultrafilter having a pore size of 0.02 to 0.05 microns, with a molecular weight cutoff of 120,000 daltons, sufficient to filter one blood volume. The preferred replacement fluid is ultrapheresed normal plasma. The patient is preferably treated daily for three weeks, diagnostic tests conducted to verify that there has been shrinkage of the tumors, then the treatment regime is repeated. The treatment is preferably combined with an alternative therapy, for example, treatment with an anti-angiogenic compound, one or more cytokines such as TNF, gamma interferon, or IL-2, or a procoagulant compound. The treatment increases endogenous, local levels of cytokines, such as TNF. This provides a basis for an improved effect when combined with any treatment that enhances cytokine activity against the tumors, for example, treatments using alkylating agents, doxyrubicin, carboplatinum, cistplatimum, and taxol. Alternatively, the ultrapheresis treatment can be combined with local chemotherapy, systemic chemotherapy, and / or radiation.

The invention discloses a dandruff control shampoo containing traditional Chinese medicines and a preparation method of the same. The shampoo is prepared from a traditional Chinese medicine extract and a hair emulsifier; and the preparation method of the dandruff control shampoo comprises the following steps of: adding the traditional Chinese medicine extract into prepared shampoo, and uniformly mixing the mixture, wherein the traditional Chinese medicine extract comprises the following parts of herbal extracts by weight: 1-5 parts of radix paeoniae rubra microwave extract, 1-5 parts of cocklebur fruit microwave extract, 1-5 parts of black sesame microwave extract, 1-3 parts of moxa leaf ultrasonic extract, 1-3 parts of radix paeoniae rubra ultrasonic extract, and 1-5 parts of cocklebur fruit ultrasonic extract. The dandruff control shampoo containing the traditional Chinese medicines disclosed by the invention can be used for solving the problems of dandruff, greasy hair, pruritus and the like of scalp; functional liquid medicine can penetrate into the scalp to develop medical effect so as to condition scalp environment; and therefore, bacteria and fungus on the scalp can be inhibited, scalp replacing speed can be reduced, pruritus of the scalp can be relieved, blood circulation of the scalp can be accelerated, grease on the scalp can be removed, the absorption of hair follicles to nutrient components can be improved, and the effects of removing dandruff, relieving pruritus and balancing grease on the scalp can be achieved.

Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.

The present invention is directed to a novel method for treating or preventing systemic inflammation in a formula-fed infant. The method administering to the infant a therapeutically effective amount of LGG in combination with at least one LCPUFA.

Selective antagonists of A2A adenosine receptors like those of formula I are provided, wherein Y forms a ring.The novel A2A blockers are useful for the treatment of Parkinsons disease and other diseases.

The invention relates to stomatology and perfume industry in particular to therapeutic formulation for oral cavity care. The invention refers to oral hygiene means and can be applied for preparation of medical and prophylactic tooth-pastes, gels, liquids for oral care as well as other compositions like chewing gums, jellies, etc. Formulation containing orally applicable active and inert components involves bromelain in amount of 0.01÷1 wt %, xylitol 1.5÷20 wt %. At best bromelain content is 0.1—0.8 wt %, xylitol content—2.2-18 wt %. For attaining remineralizing effect formulation contains anti-carious mineral additive 0.05-3.0 wt % of the list of active components. At best anti-carious mineral additive content is 0.2-2.5 wt %. There are used calcium glycerophosphate and inorganic or organic magnesium salt as anti-carious mineral additive. It is acceptable to use sodium monofluorphosphate, potassium monofluorphosphate, calcium monofluorphosphate or magnesium monofluorphosphate in amount of 0.5-1.5 wt % as anti-carious mineral additive Optimum concentration is 0.8-1.1 wt %.

An implantable graft device having treated yarn is disclosed. The device includes a graft body forming a lumen defining a longitudinal axis and having proximal and distal ends. The graft body is constructed from a woven fabric having warp yarns aligned in a first direction and a weft yarns aligned in a second direction. At least one of the weft yarns and the warp yarns has an agent applied thereto defining treated yarns of the graft body.

Embodiments of the present invention relate to methods and compositions for inducing, entraining, and / or amplifying the immune response to MHC class-I restricted epitopes of carcinoma antigens to generate an effective anti-cancer immune response. The methods and compositions disclosed herein, can be used for prophylactic or therapeutic purposes. Further embodiments provide methods of treating a cell proliferative disease, such as cancer by providing to a subject in need thereof a therapeutic strategy comprising an immunogenic composition in combination with a chemotherapeutic agent.

The invention relates to anti-hair loss hair-growing liquid. The anti-hair loss hair-growing liquid is prepared from the following raw materials by percentage: 0.5 to 5 percent of radix ginseng extract, 0.5 to 5 percent of cacumen platycladi extract, 0.5 to 5 percent of radix angelicae sinensis extract, 0.5 to 5 percent of radix polygoni multiflori extract, 0.3 to 3 percent of radix rehmanniae extract, 0.3 to 3 percent of radix scutellariae extract, 0.3 to 3 percent of rhizoma zingiberis recens extract, 0.05 to 0.8 percent of tripeptide-1copper, 1 to 8 percent of palmitoyl tripeptide-1, 0.5 to5 percent of myristoyl pentapeptide-4, 15 to 30 percent of edible alcohol, 0.2 to 0.5 percent of hexanediol, 0.1 to 0.35 percent of phenoxyethanol, 0.05 to 0.30 percent of sodium citrate, 0.02 to 0.2percent of citric acid, 0.005 to 0.02 percent of essence and the balance of deionized water. The anti-hair loss hair-growing liquid disclosed by the invention has the advantages that the problems ofscalp hair loss and less hair can be solved, and the ecological environment of the scalp can be improved due to high active ingredients; a good role in hair fixation and hair growth is played, so thatthe hairs are thicker.

Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.

A method of treating an inflammation in a subject in need thereof is disclosed. The method comprises locally or systemically administering to the subject IFN-γ in an amount so as to achieve an IFN-γ bulk tissue concentration at a site of inflammation of 1-8,000 units per kilogram body weight, thereby ameliorating the inflammation.

Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.