22 results about "Gingival inflammation" patented technology

The invention belongs to the technical field of oral health care, and particularly discloses a toothpaste composition for inhibiting dental plaque and improving gingival inflammation, finished toothpaste and a preparation method thereof. The toothpaste composition is prepared from 0.5 to 10 parts of zinc carbonate hydroxide, 0.01 to 0.2 part of pearl powder, 0.01 to 0.2 part of amber powder, 0.5 to 5 parts of lactobacillus / soybean milk fermentation product filtrate, 0.05 to 1 part of borneol and 0.01 to 0.2 part of clove oil. The toothpaste composition provided by the invention inherits a classic formula, is simple in components and high in safety, and has good effects of inhibiting dental plaque and improving gingival inflammation; and the provided preparation process is simple and easy for large-scale production.

The invention discloses liquorice-source fluorescent carbon quantum dots and a preparation method and application thereof.The preparation method comprises the following steps that dried liquorice roots and stems are smashed, water is added according to the proportion of 100 mg: (10-20) mL, a hydrothermal reaction is conducted for 5-6 h at the temperature of 140-180 DEG C, filtration is conducted through a 0.22-micron microfiltration membrane after centrifugation, and a brown-yellow carbon quantum dot aqueous solution with the special fragrance and the fluorescence characteristic is obtained; obtaining the liquorice source fluorescent carbon quantum dots. Compared with a liquorice extract liquid extracted by a traditional method, the liquorice-source fluorescent carbon quantum dot disclosed by the invention has the advantages that the growth of porphyromonas gingivalis and staphylococcus aureus can be remarkably inhibited at low concentration, and the liquorice-source fluorescent carbon quantum dot has a remarkable fluorescence characteristic; the visible real-time visualization of a treatment area can be realized under the excitation of a common handheld ultraviolet light source or a blue light source, so that the administration accuracy is improved, the dental plaque aggregation on the surface of teeth is obviously reduced, and the gingival inflammation is inhibited.

The invention relates to a tooth whitening instrument control method and device, a tooth whitening instrument and a readable medium. The method comprises the following steps: determining target output power of the tooth whitening instrument according to the pigmentation degree of teeth of a user; controlling the tooth whitening instrument to output cold light according to the target output power so as to perform tooth whitening and gingival inflammation diminishing on the user; in the process of tooth whitening and gingival inflammation diminishing of the user, the tooth whitening instrument is controlled to keep the target output power unchanged until the preset end time is reached. According to the scheme, it can be guaranteed that the tooth whitening instrument emits light uniformly, and tooth whitening and gingival inflammation diminishing are more uniform and thorough.

The present invention relates to the technical field of oral care products, and specifically to a targeted anti-inflammatory and sterilizing oral care complex and a process for preparing the same. The liposome complex is a liposome co-loaded with a curcumin-luteolin metal zinc complex wrapped by a betaine surfactant, which can be used for the preparation of oral care products such as mouthwash, toothpaste, gel, etc., and the luteolin-zinc metal complex and curcumin are respectively encapsulated in the hydrophilic center and the hydrophobic bilayer of the liposome, and then the liposome surface is modified by a betaine surfactant, and the liposome surface is positively charged, which can be targeted to the gingival inflammation site. This technical solution solves the technical problem that the oral care products used to alleviate and treat gingivitis in the prior art are not targeted and have limited effects, and can penetrate deeply into the inflammation site, release curcumin and luteolin metal zinc complex, synergistically fight bacteria, remove free radicals, and achieve rapid anti-inflammatory effects.

This application discloses the use of ectoine or its derivatives in preventing and / or improving gingival damage caused by cigarette smoke, as well as methods for achieving this use. Ectoine or its derivatives can effectively prevent and / or improve gingival damage caused by cigarette smoke, thus expanding the scope of application of ectoine or its derivatives. Furthermore, ectoine or its derivatives can effectively prevent and / or improve gingival recession and / or gingival inflammation caused by cigarette smoke, and can be used in products such as oral care products.

The utility model discloses a tooth shoulder calibration preparation needle, which relates to the technical field of oral medical instruments. It includes a first preparation needle, a second preparation needle, a third preparation needle, and a fourth preparation needle. The first preparation needle includes a first base and a first needle body, and the first base is connected to the first needle body along the axial direction; the second preparation needle includes a second base, a second needle body, and a positioning groove grinding ring, and the second base is connected to the second needle body along the axial direction, and the positioning groove grinding ring is fixedly sleeved on the surface of the second needle body; the third preparation needle includes a third base, a third needle body, an auxiliary positioning ring, and a shoulder grinding ball head, and the third base, the third needle body, and the shoulder grinding ball head are sequentially connected along the axial direction, and the auxiliary positioning ring is fixedly sleeved on the surface of the third needle body; the fourth preparation needle includes a fourth base and a fourth needle body, and the fourth base is connected to the fourth needle body along the axial direction; so that the positioning is more accurate, the gums are avoided from being damaged, gingivitis can be reduced, and the aesthetic effect is improved.

The present disclosure provides methods of using secoisolariciresinol diglucoside (SDG) (including stereoisomers thereof), for example, a synthetic SDG such as LGM2605, to treat periodontitis, for example, molar-incisor pattern periodontitis (MIPP), and / or pathogen-associated gingival inflammation in a subject.

The present invention relates to a method for treating gingivitis and gingival atrophy and repairing oral mucosa in a subject, comprising a step of administering to the subject a therapeutically effective amount of an oligopeptide of the formula (I):         X1X2X3X4X5X6     (I) wherein X1 is glycine (Gly; G) or lysine (Lys; K); X2 is glutamic acid (Glu; E) or threonine (Thr; T); X3 is K or T; X4 is G or K; X5 is serine (Ser; S), phenylalanine (Phe; F) or absent; and X6 is F or absent.

The present disclosure relates to ingestible oral care compositions and their use, for example, to control plaque and / or gingival inflammation in a subject. For example, ingestible oral care compositions may comprise proteins, lipids, polysaccharides and / or derivatives thereof, and optionally active ingredients in a water-based orally acceptable carrier.

The invention provides a tooth-strengthening mouthwash and a preparation method thereof, and belongs to the technical field of oral care products, the mode of combining traditional Chinese medicine extracts and Chinese herbal medicines is adopted, the principle of monarch, minister, assistant and guide is fully applied, and the characteristics of good permeability and quick effect of modern essential oil are combined, so that the prepared mouthwash has the effects of effectively relieving gomphiasis and strengthening teeth. The teeth are stabilized; and inflammation and pain of the teeth and gingiva are relieved.

The invention discloses a lactobacillus rhamnosus for improving oral health as well as a product and application thereof, and belongs to the technical field of microorganisms. The invention aims to solve the technical problems that the existing strain is insufficient in targeting to core problems such as inhibition of oral volatile sulfur compounds (VSCs) and relieving of gingival inflammation, and is poor in adaptability to oral care products, and traditional chemical products also have side effects such as mucous membrane stimulation. The key points of the technical scheme are as follows: the lactobacillus rhamnosus MH-LR13 (preservation number is CGMCC No.37262) is provided, can specifically inhibit VSCs producing bacteria and pathogenic bacteria related to gingival inflammation, and is excellent in oral planting capacity; the application of the composition in products for improving oral health is protected, and the core effect is defined; the invention provides a composition containing the bacterial strain, an oral cavity refreshing spray and an adaptive preparation process, the product is high in safety and obviously superior to the existing bacterial strain and a commercially available product in effect through experimental verification of people, and a natural and mild long-acting solution is provided for oral health.

To provide a composition capable of exhibiting new effects of bay laurel (LaurusnobilisL.).SOLUTION: The composition contains an extract of bay laurel (LaurusnobilisL.), has an antibacterial action against Tannerellaforsythensis and Streptococcusmutans, suppresses gingival inflammation, spontaneous bleeding of gums and plaque accumulation, improves dryness in the oral cavity and saliva pH, suppresses halitosis and improves constipation. Specifically, the present invention relates to an antibacterial agent against periodontal disease-related bacteria and dental caries-related bacteria, a composition for preventing or treating periodontal disease, a composition for preventing or treating dental caries, a composition for improving gingiva, a composition for improving gums, a composition for suppressing plaque (dental plaque) accumulation, a composition for improving xerostomia, a composition for improving saliva, a composition for suppressing halitosis, and a composition for improving constipation, each of which contains a bay laurel (LaurusnobilisL.) extract as an active ingredient. By containing the bay laurel (LaurusnobilisL.) extract, it is possible to suppress Tannerellaforsythensis and Streptococcusmutans which are periodontal disease-related bacteria, suppress gingival inflammation, spontaneous bleeding of gums, and plaque accumulation, improve dryness in the oral cavity and saliva pH, suppress halitosis, and improve constipation.SELECTED DRAWING: None

The present disclosure provides methods of using secoisolariciresinol diglucoside (SDG) (including stereoisomers thereof), for example, a synthetic SDG such as LGM2605, to treat periodontitis, for example, molar-incisor pattern periodontitis (MIPP), and / or pathogen-associated gingival inflammation in a subject.

The invention belongs to the technical field of oral care products, and relates to a preparation method of a high-activity chondrus crispus extract, a functional additive and toothpaste. According to the method, during raw material pretreatment, an anti-oxidation protection solution containing sodium sulfite and cysteine is used, the high-activity extract is prepared through the steps of enzymolysis, centrifugation, ultrafiltration, reverse osmosis and the like, and the problems that in a traditional water-alcohol extraction technology preparation method, the extraction amount and purity of active ingredients are limited and the like can be solved. The extract is excellent in antioxidant, antibacterial and anti-inflammatory activity, a functional additive prepared from xylitol, hydroxyapatite and other components is added into the toothpaste, the residual area ratio of dental plaque can be reduced to 10%-15%, gingival inflammation can be effectively improved, and the gingival bleeding index of animals is reduced by 50%-60%. Meanwhile, the toothpaste is good in stability, the viscosity change under different temperature and humidity conditions is within + / -10%, and the particle size distribution is stable. Therefore, the problem that traditional toothpaste has limitation in the aspect of preventing and improving oral diseases is effectively solved.

The present invention relates to compositions and their use for oral care. In particular, the compositions and methods are for maintaining oral health and / or treating various oral conditions such as gingivitis. The present invention relates to methods and uses of stabilized amorphous calcium phosphate (ACP) and / or stabilized amorphous calcium fluoride phosphate (ACFP) in the preparation of a medicament for reducing pathogenic oral bacteria at an oral site in an individual; increasing commensal oral bacteria at an oral site in an individual; decreasing the proportion of pathogenic oral bacteria at an oral site in an individual; inhibiting oral dysbiosis; reducing gingival inflammation in an individual in need thereof; treating gingivitis in an individual in need thereof; and treating chronic gingivitis in an individual in need thereof.

The invention discloses application of recombinant human glaze matrix protein in preparation of an anti-periodontitis oral care product. The oral care product is prepared from rhEMPs, glycerin, sorbitol, poloxamer 188, sodium lauroyl sarcosinate, potassium nitrate, sucralose, xylitol, methylparaben, propylene glycol, PEG-40 hydrogenated castor oil, domiphen and water. The core innovation of the oral care product is that the stability bottleneck of rhEMPs in the physiological pH environment of the oral care product is solved by utilizing the synergistic stabilization effect of poloxamer 188 and sodium lauroyl sarcosinate, and it is found that when the oral care product is combined with components such as potassium nitrate, periodontal pathogenic bacteria can be remarkably inhibited, gingival inflammation can be relieved, and periodontal tissue repair can be promoted. The product form can be mouth wash, oral spray or toothpaste, the preparation process is simple, the stability is good, and a brand new solution is provided for daily adjuvant therapy of periodontitis.

The present disclosure relates to ingestible oral care compositions and their use, for example, to control dental plaque and / or gingival inflammation in a subject. For example, the ingestible oral care composition may include: proteins, lipids, polysaccharides and / or derivatives thereof, and optionally active agents, in a water-based, orally acceptable vehicle.

The application discloses licorice source fluorescent carbon quantum dots and a preparation method and application thereof, and the preparation method comprises the following steps: crushing dried licorice root stems, adding water in a proportion of 100 mg to (10-20) mL, carrying out hydrothermal reaction at 140-180 DEG C for 5-6 h, filtering through a 0.22 mu m microporous filter after centrifugation, and obtaining a brown-yellow carbon quantum dot aqueous solution with special fragrance and fluorescent characteristics, which is the licorice source fluorescent carbon quantum dots. Compared with a traditional method of extracting licorice extraction liquid, the licorice source fluorescent carbon quantum dots can not only achieve significant inhibition of growth of Porphyromonas gingivalis and Staphylococcus aureus at a low concentration, but also have significant fluorescent characteristics, can realize real-time visualization of a treatment area visible to the naked eye under excitation of common handheld ultraviolet light or blue light sources, thereby improving administration accuracy, and significantly reducing plaque aggregation on a tooth surface and inhibiting gingival inflammation.

The invention discloses a negative-pressure siphon bacteriostatic electric toothbrush head, which belongs to the technical field of electric toothbrushes and comprises a toothbrush handle and a toothbrush head detachably connected to the toothbrush handle. The toothbrush head comprises a storage seat, cleaning bristles, a connecting insertion rod and an outer shell; the outer shell is detachably installed on the back face of the storage base, the cleaning bristles are installed on the front face of the storage base, the connecting insertion rod is installed at the bottom of the storage base, the toothbrush further comprises a sealed negative pressure mechanism, and the sealed negative pressure mechanism is located in the toothbrush handle and extends into the storage base. A detachable back cover is arranged on the back of the storage seat, and an air bag puncturing structure is arranged on the back cover. According to the electric toothbrush, bacteriostatic active substances are accurately conveyed to a clean area through a negative pressure siphon mechanism, breeding of harmful bacteria such as streptococcus mutans and porphyromonas gingivalis is inhibited from the source, tooth enamel corrosion and gingival inflammation caused by acidic substances are avoided, and the functional blank that a traditional electric toothbrush cannot inhibit bacteria is filled.

This invention relates to the field of biopharmaceutical technology, specifically to a BTO / PB acoustic pressure electrocatalytic nanoplatform ointment, its preparation method, and its application. The ointment is an injectable BTO / PB acoustic pressure electrocatalytic nanoplatform ointment formed by combining a barium titanate and Prussian blue composite nanomaterial with an ointment. The BTO / PB acoustic pressure electrocatalytic nanoplatform ointment of this invention exhibits excellent biocompatibility. Unlike traditional antibiotics, BTO / PB generates ROS (reactive oxygen species) through an ultrasound-driven catalytic reaction, independent of antibiotics, thus eliminating the risk of drug resistance. It effectively addresses the increasingly serious problem of antibiotic resistance, has a good antibacterial effect against periodontal pathogens, significantly alleviates gingival inflammation, reduces the infiltration of inflammatory cells, lowers the expression of inflammatory factors, and effectively inhibits osteoclast activity, thereby protecting alveolar bone and maintaining the integrity of periodontal tissues.

Methods and apparatuses for assessing oral health and automatically providing diagnosis of one or more oral diseases. Described herein are intraoral scanning methods and apparatuses for collecting and analyzing image data and to detect and visualize features within image data that are indicative of oral diseases or conditions, such as gingival inflammation or oral cancer. These methods and apparatuses may be used for identifying and evaluating lesions, redness and inflammation in soft tissue and caries and cracks in the teeth. The methods can include training a machine learning model and using the trained machine learning model to provide a diagnosis of an oral disease or condition based on image data collected using multiple scanning modes of an intraoral scanner.

The utility model discloses a kind of gum massagers, mainly applied to physiotherapy apparatus technical field, contain button type latch, knurled bolt, screw rod, spring, eccentric wheel motor, neck ring, neck support, cross arm, boss, strut, screw rod seat, massage head, the neck ring is semicircular ring structure, inner wall edge is connected with neck support, the neck ring both ends extend downward, and the extension one end is rotatably connected with cross arm, the other end has button type latch, for locking or opening the other end of cross arm, the boss is vertically connected with the center of cross arm, the one end of strut is rotatably connected with boss, and knurled bolt is connected, the top end of strut has internal thread, and the screw rod is engaged with internal thread. Application the utility model of a kind of gum massager, it is convenient and fast to use, man-machine engineering is excellent, use is more comfortable, sanitary clean, can be used as household physiotherapy product, utilization is higher, manufacturing cost is low, physiotherapy effect is better, effectively prevent the occurrence of gingival atrophy and gingival inflammation.