Sodium bicarbonate whitening toothpaste containing hyaluronic acid and preparation method thereof

A technology of hyaluronic acid and oligomeric hyaluronic acid, which is applied in the field of toothpaste, can solve the problems of toothpaste stability reduction and achieve the effects of reducing the formation of sensitive teeth, simple preparation method, strong moisture retention and stability

Inactive Publication Date: 2021-04-09
SHANDONG BLOOMAGE HYINC BIOPHARM CORP LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Aiming at the deficiencies in the existing baking soda toothpaste, the invention provides a baking soda whitening toothpaste containing hyaluronic acid, which uses baking soda, hydroxyapatite, composite hyaluronic acid or its salts as functional ingredients, Through the synergistic effect of these three, the long-term whitening effect can be achieved, and the problems of toothpaste stability reduction and tooth damage caused by the use of baking soda can be overcome

Method used

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  • Sodium bicarbonate whitening toothpaste containing hyaluronic acid and preparation method thereof
  • Sodium bicarbonate whitening toothpaste containing hyaluronic acid and preparation method thereof
  • Sodium bicarbonate whitening toothpaste containing hyaluronic acid and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] 1. Take 8g hyaluronic acid (the mass ratio of hyaluronic acid with different molecular weights is: 2000kDa:700kDa:5kDa=1:3:4), 2g sorbitol, 4g food grade baking soda, 0.2g sodium pyrophosphate, 0.05g Maltitol, added to deionized water, mixed evenly to obtain the first mixed solution;

[0034] 2. Take 1g of sodium N-lauroyl sarcosinate, 5g of hydroxyapatite, and 10g of aluminum hydroxide, and mix them evenly to obtain a mixed powder;

[0035] 3. Add the mixed powder of the above step 2 into the first mixed solution, and mix evenly to obtain a paste;

[0036] 4. Add 0.01g of potassium sorbate to 0.5mL of peppermint oil, heat in a water bath until mixed evenly, and obtain the second mixed solution;

[0037] 5. Add the second mixed solution into the above paste, and stir for 25 minutes under a vacuum condition greater than 0.94Mpa to obtain a hyaluronic acid-containing baking soda whitening toothpaste with uniform texture.

Embodiment 2

[0039] 1. Take 8g hyaluronic acid (the mass ratio of hyaluronic acid with different molecular weights is: 2000kDa:700kDa:5kDa=1:3:4), 3g sorbitol, 8g food grade baking soda, 0.5g sodium pyrophosphate, 0.3g Maltitol, added to deionized water, mixed evenly to obtain the first mixed solution;

[0040] 2. Take 1.5g of sodium N-lauroyl sarcosinate, 7g of hydroxyapatite, and 18g of aluminum hydroxide, and mix them evenly to obtain a mixed powder;

[0041] 3. Add the above mixed powder into the first mixed solution to obtain a paste;

[0042] 4. Add 0.15g potassium sorbate to 0.7mL peppermint oil, heat in a water bath until mixed evenly, and obtain the second mixed solution;

[0043] 5. Add the second mixed solution into the paste, and stir for 25 minutes under a vacuum condition greater than 0.94Mp to obtain a hyaluronic acid-containing baking soda whitening toothpaste with a uniform texture.

Embodiment 3

[0045] 1. Take 8g hyaluronic acid (the mass ratio of hyaluronic acid with different molecular weights is: 2000kDa:700kDa:5kDa=1:3:4), 5g sorbitol, 13g food grade baking soda, 0.8g sodium pyrophosphate, 0.5 g maltitol, added to deionized water, mixed uniformly to obtain the first mixed solution;

[0046] 2. Take 2.5g of sodium N-lauroyl sarcosinate, 9g of hydroxyapatite, and 25g of aluminum hydroxide, and mix them evenly to obtain a mixed powder;

[0047] 3. Add the above mixed powder into the first mixed solution to obtain a paste;

[0048] 4. Add 0.25g of potassium sorbate to 1mL of peppermint oil, heat in a water bath until mixed evenly, and obtain the second mixed solution;

[0049] 5. Add the second mixed solution into the paste, and stir for 25 minutes under a vacuum condition greater than 0.94Mp to obtain a hyaluronic acid-containing baking soda whitening toothpaste with a uniform texture.

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Abstract

The invention provides sodium bicarbonate whitening toothpaste containing hyaluronic acid and a preparation method thereof. The sodium bicarbonate whitening toothpaste is prepared from the following functional components in percentage by mass: 4 to 13 percent of sodium bicarbonate, 5 to 9 percent of hydroxyapatite and 5 to 10 percent of composite hyaluronic acid or salt thereof. The sodium bicarbonate, the hydroxyapatite and the composite hyaluronic acid or the salt thereof are used as functional components; and the sodium bicarbonate, the hydroxyapatite and the composite hyaluronic acid or the salt thereof have the synergistic effect in the aspect of tooth whitening, and have the long-time whitening effect. The composite hyaluronic acid or the salt thereof is formed by compounding high and medium molecular weight hyaluronic acid and oligomeric hyaluronic acid or salt thereof; the composite hyaluronic acid or the salt thereof can relieve the adverse effects of enamel injury, gingival inflammation and the like due to long-time use of the sodium bicarbonate toothpaste; the formation of sensitive teeth is reduced; the hydroxyapatite can repair and strengthen the teeth; and through the use of the sodium bicarbonate and the hydroxyapatite, the injury of the sodium bicarbonate on the teeth can be greatly reduced.

Description

technical field [0001] The invention relates to a toothpaste, in particular to a baking soda whitening toothpaste containing hyaluronic acid and a preparation method thereof, belonging to the technical field of toothpaste. Background technique [0002] With the improvement of living standards, people begin to pay more and more attention to tooth whitening and oral health, and consumers have higher and higher demand and requirements for functional toothpaste, such as baking soda whitening toothpaste that has been sought after in recent years. [0003] Baking soda, also known as sodium bicarbonate, is easily soluble in water and has no toxic side effects. It is an excellent cleaning agent. At present, domestic and foreign markets use the characteristics of weak alkalinity and particle friction of baking soda to balance the pH of the mouth and inhibit acidic plaque in the mouth. The toothpaste achieves the effect of removing stains, whitening and freshening breath when brushin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/19A61K8/24A61K8/60A61K8/73A61Q11/00A61P1/02A61P29/00
CPCA61K8/19A61K8/735A61K8/24A61K8/60A61Q11/00A61P29/00A61P1/02A61K2800/5922
Inventor 李红红耿凤郭文逸郭学平
Owner SHANDONG BLOOMAGE HYINC BIOPHARM CORP LTD
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