2159results about "Oral care" patented technology

The invention discloses an oral care desensitization paste and a preparation method thereof, and mainly relates to the technical field of dental medicines. The oral care desensitization cream is prepared from the following components: bioactive glass, strontium chloride, sodium chloride, silicon dioxide, sodium carboxymethyl cellulose, polyethylene glycol 400, a xanthan gum solution, sodium lauryl sulfate, sodium lauroyl sarcosinate, titanium dioxide, beta-glucan, saccharin sodium salt, sorbitol, methylparaben, propyl hydroxybenzoate, edible essence and water. Compared with the prior art, the oral care desensitization paste disclosed by the invention can be used for sealing dentinal tubules and treating hemodia; the traditional Chinese medicine composition can also be used for treating plaque gingivitis, relieving and reducing gingival bleeding and inhibiting and reducing dental plaque; and meanwhile, the condition of mistakenly swallowing and eating in the using process is reduced.

The invention discloses a metal-doped carbon quantum dot as well as preparation and application of the metal-doped carbon quantum dot in a nano antibacterial agent, citric acid, urea and tea polyphenol are taken as precursors, metal salt is added, carbon dot synthesis and metal ion doping are synchronously completed in one step through a hydrothermal method, and the metal-doped carbon quantum dot is prepared; the surfaces of the metal-doped carbon quantum dots are negatively charged, and the metal-doped carbon quantum dots have peroxidase-like activity and catalase-like activity at the same time; the metal ions adopt any one of Fe < 3 + >, Cu < 2 + > and Ce < 3 + >; the metal-doped carbon quantum dots are in a sphere-like shape. The metal-doped carbon quantum dots prepared by the preparation method disclosed by the invention have peroxidase-like activity and catalase-like activity at the same time through precise doping of metal ions, and the two activities have a synergistic effect in an oral periodontitis microenvironment, so that a good antibacterial effect is achieved.

The invention discloses SGNH family esterase SH2 screened in a Tibetan hot spring environment and application of the SGNH family esterase SH2, and belongs to the technical field of gene engineering. According to the invention, a new SGNH family esterase gene is screened from a Tibetan hot spring environment, and recombinant expression is realized in escherichia coli. The recombinant esterase prepared by the invention has the characteristics of thermal stability, salt resistance, organic solvent resistance and the like, can be safely applied to tooth whitening or skin exfoliating products, avoids damage of traditional chemical bleaching agents to enamel, and has important application value in the fields of daily chemicals, medicines, food processing and the like.

The invention discloses a tooth repair composition containing mesoporous hydroxyapatite, a tooth repair product and a preparation method and application of the tooth repair composition and the tooth repair product. The tooth repair composition comprises nano-hydroxyapatite, fluoride and a chelating agent, the logarithm value logK of the stability constant K of the chelating agent to calcium ions is 1 < = logK < = 5, and K is measured in an aqueous solution with the temperature of 25 DEG C, the pH value of 7.0 and the ionic strength of 0.1 M; the nano-hydroxyapatite is prepared from nano-scale mesoporous hydroxyapatite, and the nano-hydroxyapatite contains nano-scale mesoporous hydroxyapatite. By adding the specific chelating agent, dynamic balance is formed in the tooth repairing composition, slow release protection can be formed on free calcium ions, the double inactivation effect possibly occurring when hydroxyapatite and fluoride exist at the same time is effectively avoided, the synergistic repairing effect of hydroxyapatite and fluoride is fully exerted, and the tooth repairing effect is improved. The use of fluorides can be greatly reduced, and safety and reliability are achieved.

The invention discloses an oral care composition containing ampelopsis japonica polysaccharide and application of the oral care composition in inhibiting gingival bleeding. The oral care composition comprises ampelopsis japonica polysaccharide and an orally acceptable carrier, wherein the pH (Potential of Hydrogen) range of the oral care composition is 5.9 to 7.7. The invention also discloses an application of the ampelopsis japonica polysaccharide in the oral care composition for inhibiting gingival bleeding. The invention discloses application of silicon dioxide with a high oil absorption value in an oral care composition for improving the gingival bleeding inhibiting effect of ampelopsis japonica polysaccharide. The combination of the high-oil-absorption-value silicon dioxide and the low-oil-absorption-value silicon dioxide is applied to the oral care composition for improving the gingival bleeding inhibiting effect of the ampelopsis japonica polysaccharide; the invention further discloses application of sorbitol in the oral care composition for improving the effect of inhibiting gingival bleeding by the ampelopsis japonica polysaccharide. The oral care composition has a hemostatic effect and can effectively solve the problem of gingival bleeding.

The invention provides an additive composition containing a bioactive enzyme and a preparation method of the additive composition, and belongs to the technical field of biological enzymes. The preparation method comprises the following steps: fixing phytic acid and cyclodextrin on hydroxyapatite, modifying with tannic acid, reacting with dithiothreitol modified lysozyme to prepare an immobilized compound, adding 2, 2-dimethoxy-2-phenylacetophenone and methyl methacrylate, and carrying out irradiation reaction with an ultraviolet lamp to prepare the additive composition containing the bioactive enzyme. The broad-spectrum antibacterial property and the antiviral property of the lysozyme are greatly improved, the sterilization effect on gram negative bacteria is obviously improved, meanwhile, the stability of enzyme is greatly improved, the enzyme is not prone to inactivation, the preservation time of the enzyme is prolonged, the application effect of the enzyme is widened, meanwhile, the lysozyme has good killing capacity on oral bacteria and viruses, the addition of preservatives is reduced, and the cost is reduced. The cleaning effect and stability of the product are improved, tooth demineralization can be prevented, decayed teeth can be prevented, and wide application prospects are achieved.

The invention discloses an oral care composition and a preparation method thereof, the oral care composition comprises a friction agent, a periodontal repair agent, a thickening agent, a humectant and a foaming agent, the friction agent comprises a dental plaque release agent, and the dental plaque release agent is configured to destroy a bacterial extracellular polysaccharide matrix in dental plaque; the periodontal repair agent comprises at least one of the following components: an inflammation inhibitor, a tissue repair promoter, a mucous membrane stimulation alleviator and a bacteriostatic agent. The oral care composition contains the dental plaque release agent and the periodontal repair agent, and can synergistically improve periodontal health.

The invention belongs to the technical field of medical materials, and particularly relates to a tooth whitening composition and a preparation method thereof, the tooth whitening composition comprises the following components by weight: 5%-15% of hydrogen peroxide, 0.5%-1.5% of a gel matrix, 0.2%-1.0% of a thickener, 5%-10% of a humectant, 3%-8% of propylene glycol, 0.05%-0.2% of a chelating agent, 1%-3% of a sweetener, 0.1%-0.5% of sodium fluoride, and the balance of water. Aiming at the problems that an existing tooth whitening product is relatively low in pH value (most of 4.0-5.0), easy to irritate gingiva and sensitive in tooth manufacturing, and the existing tooth whitening product needs to be stored in a dark place at a low temperature and is short in whitening validity period, the pH value of the product is adjusted to 5.5-6.5, so that the product is close to oral saliva, the irritation can be reduced, the stability of the product can be ensured, the product is not easy to decompose, and the tooth whitening effect is good. Active ingredients are prevented from losing efficacy in advance, and the whitening validity period is prolonged.

The invention discloses a surface-modified bioactive glass oral cavity desensitization paste and a preparation method thereof, and relates to the technical field of oral cavity desensitization pastes. The surface-modified bioactive glass oral desensitization paste is prepared from the following raw materials in parts by weight: 5 to 15 parts of bioactive glass, 3 to 6 parts of modifier, 3 to 5 parts of silicon dioxide, 20 to 30 parts of humectant, 0.5 to 1 part of sweetening agent, 0.5 to 1.5 parts of foaming agent, 0.5 to 2 parts of thickening agent and 60 to 120 parts of deionized water. The surface modified bioactive glass oral cavity desensitization paste prepared by the invention has excellent antibacterial performance and dentinal tubule sealing effect.

The present invention relates to a pet sterilizer and deodorizer, which belongs to the technical field of pet deodorization. The present invention promotes the long-term expression of hop extract and enhances the sterilization and deodorization effect through the synergistic effect of hop extract, persimmon tannin, and lysozyme. Furthermore, the composition is stable, natural, and pollution-free, and can be used in the oral cavity and in vitro of animals. The present invention also provides zinc ricinoleate and an antibacterial agent. Through the three-phase interaction of zinc ricinoleate, hop extract, and antibacterial agent, the overall stability is enhanced and the antibacterial time of the complex is prolonged while ensuring antibacterial and deodorizing effects. The present invention also provides a modified quaternary ammonium salt antibacterial liquid. The modified quaternary ammonium salt has enhanced stability and, when present together with zinc ricinoleate, promotes an enhanced deodorizing effect. The present invention also provides an Artemisia annua extract, a Gentiana root extract, and an Artemisia argyi extract, which can eliminate odor sources and significantly inhibit bacterial growth, thereby having significant antibacterial, deodorizing, and odor-removing effects.

The invention provides a probiotic composition for preventing and / or inhibiting oral pathogens as well as a derivative product, a preparation method and application of the probiotic composition, and belongs to the technical field of oral care. The probiotic composition comprises the following bacterial strains in parts by mass: 90 to 0.45 part of a lactobacillus rhamnosus bacterial strain A2114, 10 to 0.3 part of a plant lactobacillus bacterial strain A2124, 80 to 0.4 part of a pediococcus pentosaceus bacterial strain A2135, 250 to 0.25 part of a lactobacillus reuteri bacterial strain A21350, and 40 to 0.2 part of a plant lactobacillus bacterial strain A2109. The probiotic composition or the metabolite thereof can effectively inhibit oral pathogens such as streptococcus mutans, porphyromonas gingivalis, helicobacter pylori, escherichia coli and staphylococcus aureus. Therefore, the probiotic composition or the metabolite thereof shows a good application prospect in the aspects of preventing and relieving oral problems such as decayed teeth, periodontitis and ozostomia.

The invention relates to whitening and stain-removing toothpaste and a preparation method thereof, and belongs to the technical field of oral care. The toothpaste contains 1.5-2.5 parts of plant zymolyte, 15-25 parts of composite abrasive and the like, and the plant zymolyte is obtained by grinding walnut shell powder, beech, oyster shell and Manny root ice river mud into powder according to the mass ratio of 3: 3: 2: 1 and mixing the powder with compound enzyme liquid for enzymolysis; the composite friction agent and the chelating agent are respectively prepared by mixing substances with specific particle sizes / molecular weights according to a ratio, and also contain a film-forming agent, an enamel repairing component and the like. The preparation method comprises the following steps: preparing plant zymolyte; preparing a mixed solution; and subsequently stirring, degassing and filling. Through cooperation of multiple components, the toothpaste achieves efficient whitening, stain removal and bacteriostasis, has the effects of long-acting stain prevention, enamel repair and oxidation resistance, and solves the problems that traditional toothpaste is not thorough in stain removal, damages enamel and the like.

The invention relates to the technical field of toothpaste preparation, in particular to hydrolyzed procyanidine-containing Chinese herbal medicine nursing toothpaste as well as a preparation method and application thereof.The preparation method of the hydrolyzed procyanidine-containing Chinese herbal medicine nursing toothpaste comprises the following preparation steps: adding a humectant, a thickening agent, a surfactant, a sweetening agent and a preservative into deionized water, and uniformly stirring; uniformly stirring to obtain a mixed solution; adding the abrasive into the mixed solution, and uniformly stirring to obtain paste; and adding the active microcapsules into the paste, uniformly stirring, carrying out vacuum degassing, and filling to obtain the Chinese herbal medicine nursing toothpaste containing hydrolyzed procyanidine. The Chinese herbal medicine care toothpaste is fused with hydrolyzed procyanidine, and shows excellent oral care performance. The oral care solution has obvious inhibition capability on a plurality of common oral pathogenic bacteria, has extremely high bacteriostasis rate, and can effectively block bacterial breeding and maintain oral health from the source. Meanwhile, the toothpaste is excellent in deodorization effect and capable of rapidly decomposing oral cavity peculiar smell molecules and remarkably improving oral cavity freshness.

The invention discloses a gel composition for improving compatibility and gelling speed of a tooth whitening product. The gel composition comprises whitening gel and a catalyst, respectively filling the whitening glue and the catalyst into a double-barrel injector; when the tooth whitening gel is used, the push rod is pushed, the whitening gel and the catalyst in the double-tube barrel are squeezed out at the same time and mixed at the mixing head to form the tooth whitening gel capable of being smeared on the tooth surface of a patient, and the pH value of the tooth whitening gel is 7.5-10.0. The catalyst comprises potassium salt or strontium salt, sodium fluoride, glycerol, cross-linked polyacrylamide gels, strong alkaline substances, essence and water; the whitening gel comprises a hydrogen peroxide solution, a cross-linked polyacrylamide gel, glycerin, essence and water. The cross-linked polyacrylamide gel is adopted, the gel is resistant to strong-alkalinity and high-pH environment and various inorganic salt ions such as fluoride, sylvite or strontium salt, the prepared gel is stable in form and good in compatibility, the gel preparation process is simple, the gel is rapidly swelled when encountering water and does not huddle, and long-time standing is not needed.

The present invention relates to the use of guanidine and / or at least one guanidine salt for stabilizing aqueous products, such as cosmetics and washing and cleaning products, against microbial attack.

The present disclosure provides siloxane derivatives of amino acids that have surface-active properties. The amino acid can be naturally-occurring or synthetic, or they may be obtained via a ring-opening reaction of a lactam, such as caprolactam. The amino acid may be functionalized with a siloxane group to form a compound that is surface-active and has surfactant characteristics. The compounds have low critical micelle concentrations (CMC) as well as the ability to lower the surface tension of a liquid.

Described herein is a composite microcapsule slurry including at least one microcapsule having an oil-based core including a hydrophobic material, preferably a perfume, and a composite shell including a first material and a second material. The first material and the second material are different, the first material is a coacervate, the second material is a polymeric material, and the weight ratio in the slurry between the first material and the second material is between 50:50 and 99.9:0.1.

A toothpaste comprising: i) zinc sulfate heptahydrate; ii) glycine; iii) a silica abrasive; iv) greater than 20% by weight of water; wherein the weight ratio of zinc sulfate heptahydrate to glycine is 1: 3 to 2: 1.

The invention relates to the use of chitosan hydrochloride as a tooth enamel remineralizing agent and dental or oral care products comprising chitosan hydrochloride for medical and aesthetic use.

The invention relates to a composition with functions of protecting gingiva and repairing enamel and a preparation method of the composition, and belongs to the technical field of oral care. The composition contains a functional additive, a plant compound fermentation extract and the like, the functional additive is a mixture of corn starch, calcium phosphosilicate, hydroxyapatite, ubiquinone, sodium guaiazulene sulfonate, menthol and vitamin E, and the plant compound fermentation extract is obtained by fermenting and purifying honeysuckle flowers, radix polygonati officinalis and dandelions according to a specific proportion. Through the synergistic effect of the fermentation extract and the functional components, the problems that an existing toothpaste body is hardened, the storage stability is poor, the gingival protecting effect is short, and the enamel repairing persistence is insufficient are solved, the gingival protecting effect can be enhanced, the enamel repairing effect can be improved, the stability of the toothpaste body can be optimized, the antibacterial property and the oral mucosa relieving effect are achieved, and the oral cavity repairing effect is achieved. And the preparation process is scientific and reasonable, and is suitable for daily oral care.

The present disclosure provides tooth whitening oral care compositions comprising potassium peroxymonosulfate having improved stability and methods of using the same.

The invention is applicable to the technical field of toothpaste preparation, and particularly relates to mild stain-removing and whitening toothpaste containing diatomite and coconut shell carbon and a preparation method of the mild stain-removing and whitening toothpaste. The mild stain-removing and whitening toothpaste comprises 9-30% of Changbai Mountain diatomite abrasive, 32-38% of sorbitol, 2-4% of sodium lauroyl silicate, 2-3% of polyethylene glycol 400 and 0.5-2% of coconut shell carbon. The toothpaste is prepared from the following components in percentage by weight: 0.6 to 1 percent of polyvinylpyrrolidone, 0.5 to 0.8 percent of honeysuckle flower extract, 0.5 to 0.7 percent of pseudo-ginseng extract, 0.5 to 0.8 percent of xanthan gum, 0.1 to 0.2 percent of 1, 2-hexanediol, 0.5 to 0.8 percent of essence and water. The diatomite and coconut shell carbon used in the invention are refined natural food-grade raw materials, do not contain chemical components, have low hardness, are suitable for children and sensitive people, and do not damage enamel; the selected Changbai Mountain diatomite and coconut shell carbon with the iodine value of 1500-3000 have a synergistic effect, and the Chinese herbal medicine extract is added to assist in degerming; the adsorption, whitening and deodorizing capabilities of the toothpaste are greatly improved, and the toothpaste can quickly remove stains, whiten and remove bad breath.

An oral care composition comprising i) chlorhexidine and / or a salt thereof; ii) a vitamin B3 compound; the weight ratio of i) to ii) is 1: 30 to 1: 2.

There is herein described a dissolvable oral strip or film. In particular, the present invention relates to a dissolvable or substantially dissolvable oral strip or film comprising at least one whitening agent and at least one oral hygiene agent. There is also described a process for the manufacture of a dissolvable or substantially dissolvable oral strip or film. There is further described a method of using a dissolvable oral strip or film comprising at least one whitening agent to whiten teeth and at least one oral hygiene agent that is effective against oral health conditions.

Personal care products, such as shampoos, conditioners, hair dyes, hair removal products, cleansers, cosmetics, mascaras, and toothpastes may be formulated to include one or more surfactants, from one or more surfactant classes, such as derivatives of amino acids that have surface-active properties.

Peptides that bind with high affinity to oral cavity surfaces, such as tooth enamel, have been discovered. The peptides exhibit antibacterial and mineralizing abilities, and are useful in many aspects of oral care. A preferred peptide includes the amino acid sequence AKRHHGYKRKFH-SpSp. The peptides can be included in oral care compositions such as toothpastes and mouthwashes. The oral care compositions can be used in methods to treat or prevent diseases or conditions induced by acidophilic oral bacteria. Exemplary methods include reducing or preventing tooth decay or demineralization, biofilm or dental plaque formation, and / or bacterial adhesion to a tooth surface; and promoting mineralization of teeth surfaces.

An aqueous oleanolic acid solution, including from about 0.10 to 2.5 weight % oleanolic acid, from about 60 to 90 weight % solvent, and from about 20 to 40 weight % solubility agent, wherein the solvent includes water, the solubility agent includes sodium lauryl sulfate (SLS), and the aqueous oleanolic acid solution is substantially free of ethanol and dimethyl sulfoxide (DMSO).

Peptides that bind with high affinity to oral cavity surfaces, such as tooth enamel, have been discovered. The peptides exhibit antibacterial and mineralizing abilities, and are useful in many aspects of oral care. The peptides include the amino acid sequence AKRHHGYKRKFH-SpSp. The peptides can be included in oral care compositions such as toothpastes and mouthwashes. The oral care compositions can be used in methods to treat or prevent diseases or conditions induced by acidophilic oral bacteria. Exemplary methods include reducing or preventing tooth decay or demineralization, biofilm or dental plaque formation, and / or bacterial adhesion to a tooth surface; and promoting mineralization of teeth surfaces.

An oral care composition with retinoid compound, amino acid, and / or olive oil. An oral care composition with retinoid compound, a pentapeptide, such as palmitoyl KTTKS [SEQ ID NO. 2], and / or an olive oil. Methods of preventing gingival recession, stopping gingival recession, reversing gingival recession, decrease gum recession, increase gingival barrier protection, promoting collagen synthesis, promoting extracellular matrix synthesis, increasing gum resilience, increasing epidermal thickness and / or promoting fibrillin synthesis, in an oral cavity of an animal by contacting the oral care compositions with at least one surface of the oral cavity.

The invention provides application of polypeptide in preparation of a product for inhibiting tooth demineralization. The polypeptide with the amino acid sequence shown as SEQ ID NO: 1 can effectively adjust the pH value of the oral cavity, further remarkably inhibits tooth demineralization, and is suitable for preparing products such as oral health products, oral care products and drugs for inhibiting tooth demineralization.