15 results about "Protein fiber" patented technology

The present application relates to a kind of shellfish adhesive and probiotic protection of chitosan and lysozyme protein fiber "core-shell" microspheres and its preparation method, belong to biological base functional carrier material technical field.The method, chitosan solution containing probiotic as water phase 1, lysozyme protein fiber solution containing genipin as water phase 2, after two aqueous phases are introduced into chip channel by microfluidic platform, form droplet under the shearing action of fluorinated oil containing surfactant, and obtain "core-shell" microspheres loaded with probiotic by solidification.The shell of the microsphere is the crosslinking layer formed by lysozyme protein fiber enrichment, and the core is chitosan continuous phase.The microsphere has the characteristics of controllable structure, uniform particle size and good monodispersity, and the particle size and biological macromolecule distribution can be controlled by adjusting the flow rate ratio of oil phase and water phase of microfluidic.The carrier can enhance the interaction between microsphere and intestinal mucus layer, and improve the survival ability of probiotic in gastric acid, bile salt and digestive enzyme environment, suitable for probiotic oral delivery and functional food carrier field.

The application relates to a preparation method of high-adsorption-performance quinoa polypeptide aerogel. Firstly, WALTZ algorithm is used to predict and identify the easy-fibrillated quinoa polypeptide amino acid sequence of a quinoa protein fiber solution, the easy-fibrillated quinoa polypeptide amino acid sequence is obtained, and corresponding quinoa polypeptide is synthesized by adopting an Fmoc solid-phase synthesis method based on the quinoa polypeptide amino acid sequence; then the synthesized quinoa polypeptide is dissolved in water to form a quinoa polypeptide fiber solution; finally, the quinoa polypeptide fiber solution is mixed with a sodium alginate solution to prepare quinoa polypeptide aerogel. The WALTZ algorithm is used to predict the potential amino acid sequence of the quinoa protein which is easy to form a protein fiber, the Fmoc solid-phase synthesis method is used to synthesize quinoa decapeptide, and the high fibrillating capacity of the quinoa decapeptide is fully verified, so that efficient preparation of quinoa decapeptide amyloid fibers under neutral conditions is realized, and the quinoa decapeptide-sodium alginate composite aerogel with high adsorption performance for microplastics in water is prepared.

The present invention relates to the field of bacterial protein engineering and protein fibers applicable as metal-binding bionanomaterials. More specifically, the present invention relates to engineered bacterial endospore appendage (Ena) proteins modified to contain metal-binding polypeptide (MBP) inserts providing for stable, flexible and robust protein assemblies with metal-binding activity. In particular, the invention relates to methods for designing Ena-fusion proteins capable of self-assembling into fibers, and for recombinant production of said self-assembling Ena-MBP fusion protein subunits, assemblies and fibers, ensuring a sustainable source of biological material for use in metal mineralization, metal sequestration, and metal-removal applications such as waste water treatment, water softening, or bioremediation.

The application belongs to the technical field of textiles, and relates to an indigo pre-reducing agent, an indigo reducing paste and application thereof. The indigo pre-reducing agent is prepared from the following raw materials: isatis indigotica leaf, indigo fermentation liquor, glutinous rice wine and water; the indigo reducing paste is prepared from the following raw materials: the indigo pre-reducing agent, an alkaline compound, a sugar-based reducing agent, water, a penetrating agent and a natural thickening agent. The plant indigo reducing paste provided by the application can be used for printing and dyeing at room temperature, and the process of fixing color by high-temperature steaming in the printing process is omitted, so that energy consumption is saved. Meanwhile, the sugar-based reducing agent is used to replace the chemical reducing agent, so that damage of the traditional chemical reducing agent to protein fibers is avoided, and the printing paste can be applied to various fiber fabrics. The indigo pre-reducing agent and the plant indigo reducing paste provided by the application have wide application prospects in green textiles.

The application discloses a preparation method of a regenerated protein lyocell fiber based on ionic liquid dissolution and recovery of plush and silk fibroin, and comprises the following operation steps: S1, after waste plush or silk fibers are crushed, washed and bleached, the fibers are dissolved in a dissolving kettle by using a double-component composite ionic liquid solvent to obtain a protein ionic solution; S2, after the protein ionic solution is filtered, pre-crushed wood pulp and a thermoplastic polyurethane elastomer (TPU) are added and blended and stirred to form a uniform spinning dope; S3, the spinning dope is extruded through a circular spinneret and enters a coagulating bath to obtain a regenerated protein fiber; and S4, the regenerated protein fiber is subjected to secondary water washing, drafting, oiling, drying and cutting to obtain a regenerated protein lyocell fiber. The application prepares a double-component composite solvent by preparing a composite of N-methylmorpholine N-oxide bromide and 1-ethyl-3-methyl imidazole bromide salt, and applies the double-component composite solvent to dissolution of waste plush or silk fibers and preparation of a high-protein-content regenerated protein lyocell fiber.

The present application relates to a kind of tea fiber composite mask cloth and its preparation method, belong to daily cosmetics technical field.The modified tea fiber prepared by mixing silkworm chrysalis protein and tea extract and the modified tea fiber of microcrystalline cellulose are prepared by spunlace composite to have the mask cloth of herringbone line, the mask cloth combines the excellent antioxidant, antibacterial property of tea fiber and the skin care of silkworm chrysalis protein fiber, and the water-locking of mask cloth is improved by the tea fiber of microcrystalline cellulose modification treatment, the herringbone line on surface can enhance the structural stability, air permeability, water absorption of mask cloth, to obtain the tea fiber mask cloth with excellent water-locking, antioxidant property.

The present invention relates to extracting and processing protein concentrates, isolates, and a protein-fiber fraction from cluster bean, also known as guar beans (botanical name Cyamopsis tetragonoloba). The disclosed hexane-free, aqueous-ethanol extraction process, combined with controlled low-temperature (<75 °C) vacuum desolventization to preserve light color, bland flavor, and protein functionality, provides a sustainable, clean-label method for producing cluster bean protein concentrates and isolates suitable for direct human foods. This approach avoids the high heat and reverse-polarity extraction seen in prior art and enables food-grade, industrially scalable CPC and CPI.

The application belongs to the technical field of biomedical materials, and particularly relates to a triple helix self-assembled recombinant humanized type I collagen fiber implant, a preparation method and application thereof. The application firstly provides a recombinant humanized type I collagen, which has a unique triple helix structure and excellent self-assembly properties. Secondly, the application optimizes the self-assembly process of the recombinant humanized type I collagen to prepare a recombinant humanized type I collagen implant with ordered arrangement of collagen fibers. The implant has excellent injectability, durability, high biological safety, no pyrogen and hemolysis risk, low immunogenicity, can significantly promote the adhesion, migration, proliferation and differentiation of human skin fibroblasts, can significantly promote the adhesion, migration and proliferation of chondrocytes, and can promote the chondrogenic differentiation of bone marrow mesenchymal stem cells, and can be applied to the fields of skin, cartilage, bone and the like.

This invention discloses a method for preparing and applying drug-loaded silk protein formulations that cross the blood-brain barrier, relating to the field of biomedical materials technology. To optimize the performance of nanodelivery systems by utilizing silk protein fibers to regulate the self-assembly of bioactive particles and enhance their application value in the treatment of various diseases such as Alzheimer's, the invention specifically includes silk protein nanofibers, functional therapeutic active components, and mannose / rabies virus capsid protein. The silk protein nanofibers self-assemble to form nanoparticles, and the functional therapeutic active components utilize the self-assembly process of the silk protein nanofibers to prepare bioactive silk protein nanocarriers. This invention features a simple and convenient process. The resulting stable drug-loaded silk protein nanodelivery carrier formulation achieves high brain penetration efficiency by binding to different receptors on brain microvascular endothelial cells, providing a novel approach for the design of silk protein nanodelivery carriers.

The present application relates to the technical field of fiber winding, and discloses a flame-retardant protein fiber winding device, which comprises a winding machine body, a control panel connected to the winding machine body and two winding rollers connected to the winding machine body, the outer wall of the winding machine body is connected with a bottom plate, the top surface of the bottom plate is slidably connected with an L-shaped mounting plate, the inner wall of the vertical plate in the L-shaped mounting plate is fixedly connected with a plug-in sleeve, and the outer side of the plug-in sleeve is rotatably provided with an adhesive tape. By arranging the L-shaped mounting plate, the adhesive tape, the limiting roller and the positioning roller on one side of the winding material, the wire harness head can be reliably adhered and fixed to the outer side of the winding material. With the self-rotation of the winding material, the adhesive tape is released and accurately cut off by the cutting mechanism, so that the adhesion and fixation of the next winding material are facilitated. The structural design effectively ensures that the wire harness head is still firmly attached to the surface of the winding material after the winding material is unloaded, prevents the completed winding material from loosening, and improves the stability and reliability of the overall winding.

This invention discloses a silk warp-knitted biomimetic hook-and-loop artificial vertebral endplate assembly and its preparation method, relating to orthopedic implants. The artificial vertebral endplate comprises a sheet-like fabric endplate body, with a bonding surface for connecting the artificial intervertebral disc core or intervertebral device on its opposite sides, and a functional surface formed by a loop array. The bonding surface is formed by a warp-knitted base structure with a mesh-like base structure, while the functional surface is formed by a loop array with adjustable height, density, and end curvature from silk fibers, modified silk protein fibers, or their composite fibers. The endplate body is integrally woven using a warp-knitting process, with at least two ground combs forming the base structure and at least one yarn comb forming the loop array. The roots of the loops are integrally looped and anchored to the base structure, and the endplate body has three-dimensional interconnected pores. The hook structure surface of the bone-side hooking structure or matching hooking component cooperates with the loop array to form a mechanical interlock, and the bone integration surface is used to form a contact interface with the bone side.

The present application belongs to the technical field of biological materials, and relates to a dissolving solution for dissolving tussah silk, a dissolving method and a tussah silk protein solution. The tussah silk is a natural protein fiber of medium and short types, and the main amino acid composition of the silk fibroin is alanine (about 43.1%), glycine (about 27.27%) and serine (about 11.25%), and the characteristic amino acid sequence is (-Ala-) n . The alanine repeat sequence forms a crystalline region of the tussah silk, in which nonpolar groups are dense, the peptide chains are regularly arranged, and the hydrogen bonds between the peptide chains and the intermolecular forces are strong, so that the tussah silk has high breaking strength and tensile properties, but it is also difficult to be dissolved in conventional solvents. In view of the above problems, the present application provides a new dissolving system, which can efficiently and environmentally realize the dissolution of the tussah silk under mild conditions, and well maintain the structural integrity of the silk fibroin, thereby providing support for the application of the tussah silk in high-end textiles and biological materials.

This invention relates to a brown pigment-producing *Achromobacterium pulmonaryum* strain PHS-001 and its applications. The *Achromobacterium pulmonaryum* strain PHS-001 is deposited at the China General Microbiological Culture Collection Center (CGMCC) with accession number CGMCC No. 37838. The *Achromobacterium pulmonaryum* strain PHS-001 obtained by this invention can produce brown pigment, and the fermentation cost is low, the brown pigment extraction process is simple, and it can be used not only for dyeing protein fibers such as silk and wool, but also for dyeing synthetic fiber materials such as nylon. Furthermore, it can achieve good coloring results on fabrics containing cationic groups.

This invention relates to a polyphenol-protein fiber hydrogel stabilized by polysaccharides, constructed based on freeze-thaw cycles, its preparation method, and its applications. The hydrogel possesses a uniform microstructure, enhanced mechanical properties, excellent biocompatibility, and stability. Through repeated freeze-thaw treatment, a stable three-dimensional network structure is formed without introducing chemical cross-linking bonds. This method is simple to operate, operates under mild conditions, and effectively avoids the toxic residues that may result from chemical cross-linking. The freeze-thaw cycle-constructed hydrogel is composed entirely of food-grade components and can significantly alleviate intestinal inflammation, providing a new method for the intervention of inflammatory bowel disease and related diseases.

The application discloses an orange reactive dye and a preparation method thereof, and belongs to the fine chemical field. The orange reactive dye is prepared by using m-phenylenediamine as a coupling component, and sequentially coupling two kinds of diazonium salts through a first coupling reaction, a second coupling reaction and a third coupling reaction. An additive M composed of sodium pyrophosphate, sodium hydrogen pyrophosphate, sodium hydrogen phosphate, sodium gluconate, an anionic surfactant and sodium carbonate is added in the diazotization stage, so that the material dispersibility and the reaction conversion rate are obviously improved, and the diazotization conversion rate can reach 98.7 % in one hour. The dye has bright orange color, the maximum absorption wavelength is red-shifted, the color is deeper, the color fixing rate and the build-up are better than those of a commercially available reactive orange 6R, and the light fastness, washing fastness, wet rubbing fastness and heat pressing fastness are obviously improved. The single-color use has good level dyeing property, and the compounding can improve the blackness. The preparation process is free of refining and wastewater and residue discharge, the product can be directly dried, is green, environment-friendly and low in cost, is suitable for dyeing and printing of cellulose fibers, protein fibers and synthetic fibers, and has ecological safety and industrial application value.