16 results about "Ionophore" patented technology

Embodiments herein relate to an optical chemical sensor system that is wearable and includes a microneedle array. In one embodiment, the invention includes a chemical sensing device having a set of microneedles and sensor elements. The sensor element may include a first low refractive index gel layer, a second low refractive index gel layer, and a chromogenic ionophore sensing film disposed between the first low refractive index gel layer and the second low refractive index gel layer. In one embodiment, a retardation layer may be disposed between the sensor element and a set of microneedles. An optical emitter may be configured to emit light into the sensor element. An optical detector may be configured to receive light from the sensor element. Other embodiments are also included herein.

This invention discloses a low-leakage, high-stability magnetic sludge biochar adsorbent, its preparation method, and its application, comprising the following steps: S1: preparing a sludge biochar matrix from dewatered sludge; S2: mixing the sludge biochar matrix obtained in step S1 with nano-magnetic powder, and performing high-energy ball milling under an inert atmosphere to obtain a composite powder with a physically interlocked structure, thereby preparing the low-leakage, high-stability magnetic sludge biochar adsorbent. This invention provides a structurally stable, high-adsorption-performance, and environmentally friendly magnetic sludge biochar adsorbent that can effectively remove polyether ionocarrier antibiotics (such as maduramycin) from water, showing promising practical application prospects and environmental benefits.

Hydrocarbon enhanced ionophore-based ion-selective optodes (ISOs) and methods of their use are provided. The ISOs exhibit improved ultrasensitive ion sensing due to the addition of ultralow-polarity hydrocarbons to the sensing phase using specific ratios of sensing phase components. The ISOs can be operated under an exhaustive or non-exhaustive extraction response mode.

The present invention provides: a culture medium composition which contains an iron ionophore, and which is for promoting the production of viruses each carrying a target gene or for improving the proportion of viruses each carrying the target gene with respect to all of produced viruses in the culturing of mammalian cells having the target gene introduced therein and having virus production capability; and others.

Hydrocarbon enhanced ionophore-based ion-selective optodes (ISOs) and methods of their use are provided. The ISOs exhibit improved ultrasensitive ion sensing due to the addition of ultralow-polarity hydrocarbons to the sensing phase using specific ratios of sensing phase components. The ISOs can be operated under an exhaustive or non-exhaustive extraction response mode.

An example sensor includes a conductive electrode and an ion-selective membrane over the conductive electrode. The ion-selective membrane includes an ionophore that is selective for ionized magnesium (iMg) and at least two types of anionic lipophilic salts. The at least two types of anionic lipophilic salts may include one or more fluorinated borate salts and one or more chlorinated borate salts.

Described herein are gloves having antimicrobial properties, as well as compositions (e.g., coagulant formulations) and methods for producing such gloves. In some embodiments, the gloves comprise an ionophore-ion functional group complex (e.g., Ca2+- carboxylate complex) at the outer surface, which imparts antimicrobial properties to the gloves.

Synthetic ionophores for the active carry and transport of free ions across biological membranes in vivo, comprising coordination complexes of molecules with polarized hexa-aqua and / or tetra-aqua systems of free ionic metals and ionic salts as the ionophores, useful in transporting pharmaceutical, nutrient, and personal healthcare compounds. Also described are methods of their administration, methods of their synthesis and manufacture, and the ionophore products of such synthesis and manufacturing methods.

This invention discloses a biomimetic nanofluidic sensing membrane, its preparation method, and its applications. The biomimetic nanofluidic sensing membrane comprises a top supporting lipid bilayer membrane and a bottom anodic aluminum oxide membrane with a macroporous structure. A portion of the supporting lipid bilayer membrane corresponds to and communicates with some macropores in the anodic aluminum oxide membrane. An ion carrier is embedded in the supporting lipid bilayer membrane, and its surface is modified with cholesterol-modified aptamers and polyethylene glycol. This invention utilizes the lateral fluidity of the supporting lipid bilayer to achieve multivalent and efficient capture of aptamers. The natural antifouling properties of phospholipids and the steric hindrance of polyethylene glycol synergistically suppress non-specific adsorption, and the detection signal is amplified by the ion current rectification effect induced by the asymmetric structure. The detection limit for TNF-α is as low as 0.219 pM, and with machine learning, it can accurately distinguish six proteins. The preparation method is simple, and the detection sensitivity and specificity are high, showing broad application prospects in early disease diagnosis and high-throughput protein analysis.

Synthetic ionophores for the active carry and transport of free ions across biological membranes in vivo, comprising coordination complexes of molecules with polarized hexa-aqua and / or tetra-aqua syst

Described a coagulant formulation for use in the preparation of a material that is formed by dipping, wherein the formulation includes a lipophilic and / or amphiphilic polymeric ionophore:ion complex wherein the polymeric ionophore is a hydrophilic and / or amphiphilic polymer and wherein the polymeric ionophore:ion complex imparts antimicrobial and / or antiviral properties to the material.

The present invention is directed to novel resistance modifying agents (RMAs) compounds configured to potentiate antibiotic compounds, such as polymyxin antibiotics, including colistin, directed to multi-drug resistance (MDR) gram-negative bacteria.

An example sensor includes a conductive electrode and an ion-selective membrane over the conductive electrode. The ion-selective membrane includes an ionophore that is selective for ionized magnesium (iMg) and at least two types of anionic lipophilic salts. The at least two types of anionic lipophilic salts may include one or more fluorinated borate salts and one or more chlorinated borate salts.

The invention relates to a pyrido [1, 2-a] pyrimidine mesoion derivative containing a sulfoxide structure as well as a preparation method and application of the pyrido [1, 2-a] pyrimidine mesoion derivative. The compound disclosed by the invention has a structure as shown in a formula (I), has excellent insecticidal activity on Frankliniella occidentalis, Sogatella furcifera, aphid, Spodoptera frugiperda, Plutella xylostella, Chilo suppressalis, Prodenia litura, armyworm and the like, and can be used for drugs or medicaments for preventing and treating pests such as Frankliniella occidentalis, Sogatella furcifera, aphid, Spodoptera frugiperda, Plutella xylostella, Chilo suppressalis, Prodenia litura, armyworm and the like. The structure and the preparation process are simple, and the production cost is low. (I)

A pharmaceutical or dietary composition containing zinc combined with at least one zinc ionophore, magnesium, vitamin B6, and vitamin D, and usable for blocking the production of polypeptides by ribosomes. According to the invention, this composition can be used to block viral replication, bacterial multiplication, and / or cancer cells.

The invention relates to a pyrido [1, 2-a] pyrimidine mesoion derivative containing a diaryl sulfide structure as well as a preparation method and application of the pyrido [1, 2-a] pyrimidine mesoion derivative. The compound disclosed by the invention has a structure shown as a formula (I), has excellent insecticidal activity on spodoptera frugiperda, chilo suppressalis, plutella xylostella, ostrinia nubilalis and the like, and can be used for preparing drugs or medicaments for preventing and treating pests such as spodoptera frugiperda, chilo suppressalis, plutella xylostella, ostrinia nubilalis and the like. The structure and the preparation process are simple, and the production cost is low. (I)