116 results about "Ion selective membrane" patented technology

A metal-air battery is disclosed in one embodiment of the invention as including a cathode to reduce oxygen molecules and an alkali-metal-containing anode to oxidize the alkali metal (e.g., Li, Na, and K) contained therein to produce alkali-metal ions. An aqueous catholyte is placed in ionic communication with the cathode to store reaction products generated by reacting the alkali-metal ions with the oxygen containing anions. These reaction products are stored as solutes dissolved in the aqueous catholyte. An ion-selective membrane is interposed between the alkali-metal containing anode and the aqueous catholyte. The ion-selective membrane is designed to be conductive to the alkali-metal ions while being impermeable to the aqueous catholyte.

An iontophoresis device includes an active electrode element operable to provide an electrical potential; an electrolyte reservoir comprising an electrolyte composition; an inner active agent reservoir comprising a gel matrix and distributed in said gel matrix, a first positively charged active agent; an inner ion selective membrane deposed between said electrolyte reservoir and said inner active agent reservoir; and an outermost ion selective membrane having an outer surface, the outer surface being against the biological interface, wherein, the gel matrix comprises a hydrophilic polycarboxylated polymer having net negative charges.

In the present invention, the solid contacted ISE and the solid contacted reference are based on a conductive porous network with a solid contact and membrane disposed thereon. The porous networks are not only mechanically stable, but also provide pore structure for the solid contact and membrane to intercalate, which enhances the life time and stability of the sensors. The invention further incorporates a unique fluidic fitting sensor and sealing mechanism so that measurements can be taken at high pressures. The fitting design has many benefits, such as low cost and disposability, which allows them to be mass manufactured. These sensors can be produced for detection of many different kinds of ions by applying different types of ion selective membranes, including polyvinylchloride (PVC) based ion-selective membranes and fluorous matrixes based ion-selective membranes.

An iontophoresis device includes active and counter electrode assemblies. The active electrode assembly includes an active electrode element, an outermost ion selective membrane caching an active agent and a further active agent carried by an outer surface of the outermost ion selective membrane. The active electrode assembly may also include an inner active agent reservoir storing additional active agent, an electrolyte reservoir storing electrolyte, an inner ion selective membrane positioned between the electrolyte reservoir and the active agents. The active electrode may also include an inner withdrawable sealing liner between the electrolyte reservoir and the active agents. An outer release liner may protectively cover or overlay the further active agent and/or outer surface prior to use.

An improved ion-sensing electrode for detecting ions or polyions is provided having an electrically conducting member sheathed or coated with a layer of insulation except at an exposed, uninsulated area, where the insulation free surface of the electrically conducting member is texturized, and a polymeric membrane coated on the insulation-free surface of the electrically conducting member, where the ion selective membrane includes an ionophore. The texturized surface improves the starting EMF stability and reproducibility of the ion-sensing electrodes, and further improves membrane adherence to the electrically conducting member.

An ion selective electrode (ISE) includes an electrode body or housing having an ion selective membrane located at one end thereof and an indicator electrode formed at or adjacent to the ion selective membrane. A sealed vessel is disposed inside the electrode body, the sealed vessel holding an electrically conductive solution and a reference electrode conductor, wherein a portion of the reference electrode conductor is submerged in the electrically conductive solution. The ISE includes a conductive member having a proximal end and a distal end, wherein the proximal end of the conductive member terminates inside the sealed vessel and the distal end terminates outside the housing. The construction of the ISE keeps the reference electrode separate from the indicator electrode. Electrons are passed to the reference electrode via the conductive member obviating the need for a salt bridge. Importantly, no reference electrode is needed that connects to the inner membrane surface. The ISE operates on the double capacitor mechanism which is fundamentally different from the conventional Nernst redox reactions described in the prior art.

The invention discloses an all solid-state ion selective electrode comprising an electrode cap and an electrode core, wherein a conductive polymer layer covers the lower part of the electrode core, a layer of ion selective membrane covers the surface of the conductive polymer layer, the conductive polymer layer contains a conductive polymer and a lipophilic additive, and the thickness of the ion selective membrane is 0.5-2mm. The invention also discloses a preparation method and an application of the all solid-state ion selective electrode. The all solid-state ion selective electrode disclosed by the invention can contain such additional polymers suitable for biological sensors as polyvinyl chloride, polyurethane or silicone rubber and lipophilic or hydrophilic additives. The conductive polymer can bring stable potential performance and wide temperature adaptability. Compared with the traditional ion selective electrode, the all solid-state ion selective electrode has the advantages of no internal filling liquid, long service life, stable electrode measurement, wide temperature adaptability, less external disturbance, easiness and convenience for use, non-maintenance, etc.

A micromachined device such as a solid-state liquid chemical sensor for receiving and retaining a plurality of separate liquid droplets at desired sites, a method of making the device and a method of using the device are provided. The technique works for both aqueous and solvent-based solutions. The device includes a substrate having an upper surface, and a first set of three-dimensional, thin film well rings patterned at the upper surface of the substrate. Each of the wells is capable of receiving and retaining a known quantity of liquid at one of the desired sites through surface tension. A method for patterning a membrane/solvent solution results in reproducibly-sized, uniformly-thick membranes. The patterning precision of this method allows one to place the membranes closer together, making the sensors smaller and less expensive, and the uniform film thickness imparts reproducibility to the sensors. The final film thickness can be controlled over a 3 to 50 micron range, and lateral dimensions can be as small as 20 microns using conventional materials. The simple patterning steps can be done on full wafers in a mass fabrication process. A second set of well rings may be photo-patterned at the same time as the first set of well rings to isolate functional groups on top of ion-selective membrane.

The invention relates to a diaphragm containing a non-solid-state electrode for a chemical power supply system. The diaphragm is characterized by being an intermolecular force type ion exchange membrane, which comprises two basic components including a matrix and molecules with ion exchange activity, wherein the two components are bonded by means of intermolecular force, the component of the matrix of the membrane is selected from organic polymer compounds, preferably one or some of PMMA (Polymethyl Methacrylate), PP (Propene Polymer), PE (Poly Ethylene), PVDF (Polyvinylidene Fluoride), PTFE (Polytetrafluoroethylene), PVA (Polyvinyl Acetate), PVC (Polyvinyl Chloride), PAN (Polyacrylonitrile), PEO (Polyoxyethylene Oxide), CMC (Carboxy Methylated Cellulose), starch and polyacrylic acid, and the ion exchange active molecules are selected from micromolecular organic or inorganic acids, alkaline metal and alkali or salt of alkaline-earth metal. The diaphragm only allows alkaline metal ions, alkaline-earth metal ions or hydrogen ions and the like to pass through and doe not allow transition metal ions to pass through. The diaphragm is low in manufacturing cost and easy for industrialization realization, and has potential application values in the fields of flow batteries, air batteries and fuel batteries.

Exosomes carry microRNA biomarkers, occur in higher abundance in cancerous patients than in healthy ones, and because they are present in most biofluids, including blood and urine, can be obtained non-invasively. Standard laboratory techniques to isolate exosomes are expensive, time-consuming, provide poor purity, and recover on the order of 25% of the available exosomes. We present a new microfluidic technique to simultaneously isolate exosomes and preconcentrate them by electrophoresis using a high transverse local electric field generated by ion-depleting ion-selective membrane. We use pressure-driven flow to deliver an exosome sample to a microfluidic chip such that the transverse electric field forces them out of the cross flow and into an agarose gel which filters out unwanted cellular debris while the ion-selective membrane concentrates the exosomes through an enrichment effect. We efficiently isolated exosomes from 1×PBS buffer, cell culture media and blood serum. Using flow rates from 150 μL/hr to 200 μL/hr and field strengths of 100 V/cm, we consistently captured between 60% to 80% of exosomes from buffer, cell culture media, and blood serum as confirmed by both fluorescence spectroscopy and nanoparticle tracking analysis. Our microfluidic chip maintained this recovery rate for more than twenty minutes with a concentration factor of 15 for ten minutes of isolation.

The present invention provides a device and methods of use thereof in concentrating a species of interest and/or controlling liquid flow in a device. The methods, inter-alia, make use of a device comprising a fluidic chip comprising a planar array of channels through which a liquid comprising a species of interest can be made to pass with at least one rigid substrate connected thereto such that at least a portion of a surface of the substrate bounds the channels, and an ion-selective membrane is attached to at least a portion of the surface of the substrate, which bounds said channels, or which bounds a portion of a surface of one of said channels. The device comprises a unit to induce an electric field in the channel and a unit to induce an electrokinetic or pressure driven flow in the channel.

The invention relates to a carbon dioxide biochemical analysis dry plate and a preparation method thereof, and belongs to the technical field of blood-gas biochemical sensors. The dry plate is used for detecting the concentration of carbon dioxide in a body fluid, and comprises a supporting layer, an insulating layer, a salt bridge, electrodes, a reference layer, a carbonate ion selective membrane and a buffering layer. According to the preparation method, metal/metal salt thin slice electrodes are prepared, the reference layer is attached onto the electrodes, the ratio of sodium chloride to potassium chloride in the reference layer and the water content of the reference layer are constant, the carbonate ion selective membrane and the buffering layer are sequentially attached onto the solid reference layer, carbon dioxide selective electrodes are prepared, and hydroxyl vinyl resin is utilized as a bonding agent for the carbonate ion selective membrane. The prepared dry plate provided by the invention overcomes the defects that the conventional ion selective electrode is complex to operate, high in use cost and maintenance cost, slow in response, not easy to carry, and the like, and has the advantages of being simple to operate, high in response speed, small in size, simple in preparation process, low in production cost, and suitable for industrialized production.

An electrolysis cell assembly to produce diluted Sodium Hydroxide solutions NaOH and diluted Hypochlorous Acid HOCl solutions having cleaning and sanitizing properties. The electrolysis cell consists of two insulating end pieces for a cylindrical electrolysis cell comprising at least two cylindrical electrodes with two cylindrical ion selective membranes arranged co-axially between them. The method of producing different volumes and concentrations of diluted NaOH solutions and diluted HOCl solutions comprises recirculating an aqueous sodium chloride or potassium chloride solution into the middle chamber of the cylindrical electrolytic cell and feeding softened filtered water into the cathode chamber and into the anode chamber of the cylindrical electrolysis cell.

The invention discloses a method for preparing peroxysulfuric acid by a sonoelectrochemical method, which is characterized in that in the method, a sulphuric acid solution is placed in an electrolyzer; pure platinum serves as an anode, and a lead board or thermal shock graphite serves as a cathode; the cathode and the anode are separated by a sulfonic group anion selecting membrane; an ultrasonic is added at the bottom of the electrolyzer; the electrolysis temperature is 0-40 DEG C, and the electrolysis voltage is kept between 3V and 7V, and the current density is 1000A/m<2>-6000A/m<2>; the frequency of the added ultrasonic is 20kHz-100kHz, the sound intensity of the ultrasonic is 5-20W/m<2>, and the electrolysis time of the ultrasonic is 1-5 hours; and sulfate radicals in the sulphuric acid solution at the anode zone is subject to an oxidation reaction to produce the peroxysulfuric acid. Compared with the conventional method for preparing peroxysulfuric acid by the high concentration synthesis method, the invention has the advantages of simple method, reduced energy consumption, shortened reaction time, higher activity of a generated oxidant and the like.

The present invention is a sensor for detecting urea using a separating-style structure of ion-selective electrode, in which an ammonium ion-selective membrane is immobilized on a conductive layer on the surface of a substrate, said conductive layer has a sensing region and a non-sensing region after packaged, and a conductive line is used to retrieve a sensing signal from said conductive layer. In the end, employing the enzyme immobilization method to immobilize a urea enzyme onto ammonium ion-selective membrane, thus the fabrication of a potentiometric urea sensor is completed.