A single component silicone sealant used for a solar module and a manufacturing method thereof are characterized in that the structural formula is as the right formula, n is equal to Alpha between 100 and 2000, according to part by weight, Omega-dihydroxyl dimethicone is 100 parts, petroresins is 1-5 parts, activated chalk is 10-40 parts, and silica micropowder is 30-70 parts, all the materials are added into a vacuum kneader and dehydrated and blended for 30-200 minutes under the conditions of the temperature of 100-150 DEG C and the vacuum degree of 0.06-0.099MPa, and the base stock is obtained after cooling; at room temperature, 1-5 parts of pyrogenic silica, 10-17 parts of crosslinkers, 1-3.5 parts of silane coupling agent, 0.5-1.5 parts of catalysts and 1-10 parts of silicone oil plasticizers, according to parts by weight, are further added into a high-speed dispersator or a planetary stirrer filled with the base stock and stirred for 30-150 minutes under the conditions of the vacuum degree of 0.06-0.099MPa and the rotating speed of 200-600rpm, thus preparing the single component silicone sealant. The single component silicone sealant has excellent weathering resistance and yellowing resistance, low moisture-vapor transmission and good storage stability.