System for drug iontophoresis driven by triboelectric field

A technology of iontophoresis and triboelectricity, which is applied in the direction of electrotherapy and treatment, can solve the problems of limited application, expensive special instruments and equipment, safety, portability, applicability and maintenance, and achieve long service life, Improved friction efficiency and ease of processing

Active Publication Date: 2013-12-04
NAZHIYUAN TECH TANGSHAN LLC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the traditional electric field drug iontophoresis method requires expensive special instruments and equipment, and requires professional medical technicians to operate
These may lead to problems in terms of safety, portability, applicability and maintenance, which limit its application in daily life

Method used

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  • System for drug iontophoresis driven by triboelectric field
  • System for drug iontophoresis driven by triboelectric field
  • System for drug iontophoresis driven by triboelectric field

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] figure 1 It is a specific embodiment of a system for triboelectric field-driven drug ion introduction. As shown in the figure, the system includes a triboelectric generator 8, a rectifier 2, a drug ion carrier 3 and an electric field electrode 6, and the triboelectric generator 8 is connected to the rectifier 2 To convert the alternating current generated by the friction generator 8 into direct current. The rectifier 2 includes two DC electrodes (DC output terminals), one of which is connected to the electric field electrode 6 , and the other is connected to the human skin 4 , forming a DC electrostatic field 5 between the electric field electrode 6 and the human skin 4 .

[0038] The friction generator 8 is a multilayer film type. The friction generator 8 is placed in parallel with the electric field electrode 6 in the same direction, and an insulating isolation layer 7 is set between the friction generator 8 and the electric field electrode 6, that is, at the first e...

Embodiment 2

[0049]This embodiment provides another specific embodiment of a system for driving drug ion introduction by a triboelectric field. The difference from Embodiment 1 is that the structure of the triboelectric generator 8 is different. In this embodiment, the triboelectric generator 8 is a fully transparent structure based on a high molecular polymer. The triboelectric generator 8 is like a sandwich structure consisting of two different polymer sheets stacked on top of each other with an intervening film in between. The triboelectric generator 8 includes a first electrode 40 , a first high molecular polymer insulating layer 42 , an intermediate film 44 , a second high molecular polymer insulating layer 45 and a second electrode 41 placed in sequence.

[0050] Such as Figure 4 As shown, polyethylene terephthalate (PET) is used as the first polymer insulating layer 42, and polyethylene terephthalate (PET) is used as the second polymer insulating layer 45. A conductive thin film...

Embodiment 3

[0059] This embodiment provides another specific embodiment of a system for driving drug ion introduction by a triboelectric field. The difference from Embodiment 1 is that the structure of the triboelectric generator 8 is different. also like Figure 4 As shown in the structure, the difference is that the first polymer insulating layer 42 adopts a rectangular (4.5cm×1.2cm) polyimide film (thickness 125μm, DuPont 500HN, Kapton), one surface of which is coated by sputtering The first electrode 40 is plated with an alloy metal film (thickness 100nm, Au); the first polymer insulating layer 45 is also a rectangular (4.5cm×1.2cm) polyimide film (thickness 125μm, DuPont 500HN, Kapton), and an alloy metal film (thickness 100nm, Au) used as the second electrode 41 is plated on one surface by sputtering coating method, and the intermediate film 44 is flexible polymethylmethacrylate (thickness 50μm , PMMA), a first electrode 40 and a second electrode 41 with a regular quadrangular pyra...

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PUM

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Abstract

The invention discloses a system for drug iontophoresis driven by a triboelectric field. The system comprises a friction generator, a rectifier, a drug ionophore and an electric field electrode, wherein the friction generator is connected with the rectifier; the rectifier comprises two DC output terminals, one of the DC output terminals is connected with the electric field electrode, and the other DC output terminal is connected with a drug acceptor so that a DC electric field is formed between the electric field electrode and the drug acceptor; the drug ionophore is arranged in a DC electric filed; and the friction generator is a film type friction generator, and is arranged in parallel with the electric field electrode and isolated by an insulation isolation layer from the electric field electrode. According to the system for drug iontophoresis driven by the triboelectric field, the stable pulse type DC electric field is formed between the electric field electrode and the drug acceptor so that the drug iontophoresis into human skin can be effectively and safely facilitated.

Description

technical field [0001] The invention relates to a medicine ion introduction device, in particular to a system which utilizes an electric field generated by friction to promote medicine ion introduction into human skin. Background technique [0002] With the continuous improvement of modern living standards and the accelerated pace of life, portable personal health care devices can meet people's pursuit of personal health and will become an indispensable part of people's future life. Multifunctional intelligent devices such as sensors and medical care devices with special functions and effects on the micron or even nanoscale will provide human beings with unprecedented health protection, and the simple, efficient and portable features will help the commercial popularization and daily life of these devices. application. The electrical stimulation drug introduction method has been widely used in beauty care and treatment of some diseases. Direct current electric field iontoph...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N1/30
Inventor 王中林徐传毅范凤茹
Owner NAZHIYUAN TECH TANGSHAN LLC
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