865results about How to "Reduce the chance of infection" patented technology

The invention discloses a CRISPR Cas9 system for Bacillus subtilis genome edition and an establishment method thereof, belonging to the technical field of gene engineering. A knock-out plasmid PHY300dsrf is established; and the plasmid comprises sgRNA and cas9 genes of the specific targeted target gene, a homologous restoration arm, and replication initial points and tolerance screening markers of Escherichia coli and Bacillus subtilis. The sgRNA of the specific targeted srfA-C gene can guide the cas9 protein to cut double strands at the specific site of the srfA-C gene, and can be used for accurate homologous recombination on the genome under the guide of the homologous restoration arm, thereby introducing the XhoI enzyme digestion site at the rupture. When the tank feed fermentation culture is carried out on the Bacillus subtilis of which the srfA-C gene is successfully knocked out, the foam is obviously reduced, which proves that the CRISPR / Cas9 gene editing system can effectively perform gene edition on the Bacillus subtilis genome.

The invention belongs to the technical field of intelligent robots and discloses an epidemic prevention robot and a control system thereof. The epidemic prevention robot comprises a robot body, a mechanical part and an electric appliance part, wherein the mechanical part comprises a moving chassis, a disinfectant storage box, a rotating table, an ultraviolet lamp box, a disinfection sprayer, and an intelligent recognition head; the electric appliance part comprises a laser radar, a servo motor outline, a control mainboard, a thermal imager, a portrait recognition module, a voice system and thelaser radar; a disinfection mode comprises an ultraviolet disinfection mode and a disinfectant spraying mode, and double disinfection sterilization is carried out through disinfectant spraying and ultraviolet irradiation. The epidemic prevention robot replaces manual work and is mainly used for safety epidemic prevention work; the functions of intelligent cruising, face recognition, remote shouting, autonomous charging, body temperature monitoring, voice alarm, disinfection sterilization and the like are provided, the robot can be greatly popularized in medical places, public places with large personnel flow and the like, and the probability that personnel are infected is greatly reduced.

The invention discloses a method for producing enramycin by using microbial fermentation. The method comprises the following steps of: preparing spore liquor of streptomyces fungicidicus SDSL1205 CGMCC No. 3933, and preserving the spore liquor under the environment of liquid nitrogen; inoculating the frozen and preserved spore liquor into a seed culture medium to culture seeds so as to obtain seed liquor; inoculating the seed liquor into a fermentation medium for fermenting and culturing according to the inoculum size of between 4 and 6 weight percent; and further processing fermented fermentation liquor to obtain enramycin crystals. The method has the advantages of omitting complicated seed making process, reducing microbiological contamination rate, along with simpleness and practicability, easy control of inoculum size, stable fermentation result and high repeatability. Compared with the conventional process, the method improves the fermentation result to some extent; and the maximum yield of the enramycin is over 8,500 mu g / ml (HPLC).

The invention belongs to the technical field of culture of potato, and particularly discloses a cost-saving and yield-increasing culture technique for southern winter planting potato. The technique comprises the following steps of: selecting a land, preparing the land and furrowing; applying a base fertilizer; treating potato seeds; seeding; covering with soil; covering with a film; earthing up the film; managing liquid manure, weeds and insect pests; and harvesting, wherein a method of earthing up the film is that: a layer of smashed soil of 5-8 centimeters is covered on the film by using a machine or a hoe, so that the film on a ridge surface is covered fully. In the technique, an integral water manure furrow application method is used innovatively, so that the labor per acre is saved by 7 persons, and the acre yield is up to 9,136 jin. Due to the adoption of the technique, the increase in of the yield of potato is facilitated, the production cost is lowered, and the economic benefit of potato production is increased. On the aspect of technique, the process flow of potato production is completed, the production time of potato is shortened, and a solid technical foundation is laid for the popularizing scale, standardization and commercial production of the potato industry.

The invention provides a novel biological-material complex patch which is of a laminated structure comprising a basic layer and an additional layer. The novel biological-material complex patch is characterized in that the basic layer is an patch made from an artificial synthetic material; the additional layer is a biological patch made from an extracellular matrix / acellular tissue matrix material, or a synthetic-material patch made from an artificial synthetic biological material or the artificial synthetic biological material and an artificial synthetic degradable material; and the basic layer and the additional layer are integrated through a surgical suture or a medical adhesive or other methods. The biological-material complex patch has the advantages of easiness for peripheral tissue growth and angiogenesis, adhesion prevention, degradability, good infection resistance and the like of the biological material and the advantages of easiness for tissue growth by of a big mesh, excellent infection resistance, difficulty for generating hydrops, non-degradability, high late mechanical strength and durability of the artificial-synthetic-material patch, adopts a simple production method, is more effective after being applied in clinic, and ensures recent and late relapse and infection rates to be lower.

The invention discloses a making method of clindamycinum phosphate injection, which is characterized by the following: dissolving certain quantity of clindamycinum phosphate into water; adding clindamycinum phosphate and sodium hydroxide alternately; maintaining pH value between 6.0 and 6.4; stirring evenly; setting constant volume to the density of injection; adding 0.05% needle active carbon to adsorb the injection; filtering through 0.45um micropore film or corresponding cylinder filter; sterilizing; canning; sealing; obtaining the product.

The invention discloses an intelligent supervision system for medical hand hygiene compliance. The data transmission is conducted between the front-end processor of a software monitoring platform and an AP based on a TCP / IP interface. The data communication of the AP is realized based on the connection with name tags based on 433M / 2.4G signals. The types of equipment and the fixed IDs of equipment can be preset by an identifying device. The identifying device and name tags are in communication based on 125K radio frequency signals. The position identifying and the positioning of name tags are realized based on 125K radio frequency signals. A name tag reader is respectively in communication with the front-end processor, the AP and name tags based on 433M / 2.4G signals. According to the technical scheme of the invention, the probability of nosocomial infection due to the unfulfillment of hand hygiene during the medical activity procedure can be reduced.

The invention provides a repair material for biological derivative tendon. The material takes homogeneous or heterogeneous tendon as a raw material and is formed through disinfection, degreasing, deproteinization, decellularization, freeze drying, depolymerization, devillication recombination and secondary disinfection. A method for preparing a tendon scaffold material comprises the following steps that: on one hand, a periphery structure of a tendon tissue is destructed through treatment processes of removing soft tissues, the disinfecting, the degreasing and the decellularization, and the repellency of a transplantation receipt to the tendon is reduced; on the other hand, a basic mechanism, partial enzyme activity of the tendon tissue and the continuity of the tendon tissue are further maintained through a freeze drying process so as to provide a good scaffold structure for the revascularization and cell tissue of the tendon.

The invention relates to a method for cultivating saussurea involucrate cell, wherein it comprises that using MS basic culture medium wit some NNA (fruitone), 6-BA (6-aminopurine) as the culture medium of callus; inducing the seed of saussurea involucrate into plant; using said plant as expalnt to be differented at special condition, to induce callus; subculturing the callus periodically, to increase the callus; using part of callus to function the seed and collecting the left to be dried as the saussurea involucrate culture; collecting said culture to be dried as the cell culture. The invention can improve the content of effective components.

The present invention discloses a pearl nucleus processing method for culturing nucleated pearl which comprise the following steps: (1)Choosing pearl nucleus of 12-17mm diameter, (2) purifying pearl nucleus, washing pearl nucleus with 5-10% dilute hydrochloric acid, then washing repeatedly with limewater until the pearl nucleus is neutral in pH, placing pearl nucleus in boiled water for disinfection; (3) activating the immersed pearl nuleus, placing pearl nucleus in activation liquor and processed pearl nucleus is obtained. The present invention purifies the pearl nucleus and activate the pearl nucleus before transplanting that effectively promote the tropism of pearl oyster to pearl nuclus reduce the cut infection probability of nucleus-transplanting tissue quick the healing rate of wound, promote the forming quality of pearl sac, reduce the surface blemish forming rate of nucleated pearl, promote the yield of nucleated pearl.

The invention provides a device for subpackaging culture mediums. According to the device for subpackaging the culture mediums, culture dishes comprising dish covers and dish bottoms descend along a first pushing rod, a clamping part retracts inwards to clamp the dish covers tightly, the dish bottoms continue to descend to a horizontal rotating tray of culture dish separating equipment, and the first pushing rod continues to descend to the position below the horizontal rotating tray; the dish bottoms and the dish covers rotate together along with the culture dish separating equipment, and the horizontal rotating tray rotates to the position above a second pushing rod; after the culture mediums are injected, the second pushing rod pushes the dish bottoms upwards, so that the dish bottoms are made to make contact with the dish covers; the clamping part is loosened, the dish bottoms are covered with the dish covers, and the culture dishes injected with the culture mediums are recovered. According to the device for subpackaging the culture mediums, the continuity, speediness, quantification and the automation of subpackaging can be achieved, and the compatibility to the outlines, the diameter sizes and heights of the culture dishes is good; particularly, the device can be used for subpackaging novel culture dishes of which the diameter of dish bottoms is larger than the diameter of dish covers.

Disclosed is a single needle integrated artificial pancreas, wherein the single needle integrated artificial pancreas comprises a drug reservoir unit (1); a dosing drive unit (2) connected to the drug reservoir unit (1); an indwelling unit (3) connected to the drug reservoir unit (1) and comprising a glucose sensor (31), an insulin-indwelling hose (32), a puncture needle (33) and a mounting means (34), wherein the glucose sensor (31) and the insulin-indwelling hose (32) are simultaneously implanted in the same subcutaneous tissue in a patient via the mounting means (34) under the aid of the puncture needle (33), and the puncture needle (33) is a puncture steel needle or groove puncture needle; and a blood glucose monitoring and insulin administration control unit (4) is respectively connected to the drug reservoir unit (1), the dosing drive unit (2) and the indwelling unit (3). The single needle integrated artificial pancreas is able to simultaneously implant the insulin-indwelling hose (32) and the glucose sensor (31) of the artificial pancreas into the same site of a subcutaneous tissue in a patient, thus reducing the chance of a diabetic patient being infected; and is simple in installation and convenient to use.

The invention provides a fully-water soluble fertilizer and relates to a fertilizer. The fully-water soluble fertilizer consists of K2SO4, (NH4)2SO4, urea, monoammonium phosphate, fulvic acid potassium, zinc, boron, a plant growth regulator and naphthylacetic acid, and the mass percentage occupied by the components is shown as follows: 30-50 percent of K2SO4, 30-40 percent of (NH4)2SO4, 3-8 percent of urea, 5-15 percent of monoammonium phosphate, 10-30 percent of fulvic acid potassium, 1-3 percent of zinc, 1-3 percent of boron, 0.3-0.8 percent of plant growth regulator and 0.3-0.8 percent of naphthylacetic acid. The fully-water soluble fertilizer has the beneficial effects that the fully-water soluble fertilizer is formed by adopting high-quality imported N, O and K as main materials, adding trace elements, i.e. zinc and boron, mixing auxin DA-6, and refining and processing; the fully-water soluble fertilizer has the effects of cold resistance and drought resistance, enhances the photosynthesis of crops, is a necessary nutrient element for maintaining a chloroplast structure, has remarkable effect on paper plant growth metabolism and facilitates the growth and the development of the crops; the infection risk of cottons, wheat, melons and fruits, and other virus and diseases can be reduced; and the fully-water soluble fertilizer is the high-quality fertilizer for supplanting crop nutrition and has the characteristics of fast dissolution, full dissolution, yield increment, efficiency increment and the like.

The invention relates to medical equipment, in particular to simple automatic peritoneal dialysis equipment. The equipment comprises a raw water filter, an EDI electric deionizater and a raw water processing device composed of I and II class reverse osmosis units, a peritoneal dialysis liquid confecting device composed of a dual-cavity proportioning pump, a peritoneal dialysis liquid confecting three-way solenoid valve and a peritoneal dialysis liquid container, a peritoneal dialysis treating device composed of a peritoneal dialysis treating three-way solenoid valve, an abdominal cavity inner guide coupling, a waste liquid container and a negative pressure pump as well as an automatic control system composed of an ARM singlechip which carries out finishing and programming on the collected signal; wherein the signal input interface of the ARM singlechip is respectively connected with the raw water processing program module, a treating program module, a correction treating program module and a safe monitoring program module, and the signal output interface thereof is connected with a power driver which controls the external parts under the instruction of the ARM singlechip. The invention integrates water treatment, peritoneal dialysis liquid confecting and automatic peritoneal dialysis treatment, totally closed type one machine treatment is realized, and treating expense can be greatly reduced.

The invention provides a glucan-based transparent hydrogel dressing and a preparation method thereof. The preparation method of the glucan-based transparent hydrogel dressing comprises the following steps: conducting a reaction between a glucan quaternary ammonium salt derivative and succinic anhydride; then promoting an obtained product to react with small molecules of amination, so that a macromonomer which contains illuminated cross-linking double bonds is obtained; mixing the macromonomer which contains illuminated cross-linking double bonds with an antibacterial agent and an initiating agent; conducting photo initiation so as to prepare a glucan-based transparent hydrogel; and combining the glucan-based transparent hydrogel with a polyurethane film by virtue of a bonding agent, so that the glucan-based transparent hydrogel dressing is prepared. The finished product (the glucan-based transparent hydrogel dressing) prepared by the invention not only can absorb a great amount of wound exudates so as to keep a wound surface wet, but also can avoid wound adhesion, so that the probability of wound infection is reduced and wound surface healing is promoted.

The invention relates to a virus preparation or vaccine production method by culturing cells with a polyester fiber carrier. The method particularly comprises the following steps: 1) preparing a polyester fiber cell culturing carrier by adopting a processing method; 2) in a cell culturing system, culturing proliferation cells in a cell proliferation culture solution with the treated polyester fiber cell culturing carrier; 3) changing a cell maintaining culture solution after the cells grow to a certain density or number, and inoculating virus to infect cells; 4) amplifying virus; 5) harvesting virus fluid; 6) inactivating or implementing living vaccine treatment according to the required preparation type; 7) concentrating, purifying and cracking the virus fluid; 8) adding a stabilizing agent and an immunoadjuvant; and 9) packaging vaccine. According to the method, a material which has low price and is suitable for wall attaching growth of the cells is used to make the cell culturing carrier, carry out cell culture and prepare virus or produce vaccine, so that the cost of the cell carrier is greatly reduced.

The present invention discloses a bed cleaning free and automatic cocooning sericiculture process, executed by the steps of (1) positioning of silkworm to a rearing table, (2) silkworms breeding on the rearing tables, (3) larvas selection through batch process, (4) moulting hormones addition, (5) automatic cocooning and (6) rapid gathering of cocoons. By introducing the automatic cocooning technique without bed cleaning, the present invention effectively alleviates the contradiction of deficiency of the labor and large labor intensity in sericiculture, depresses the sericiculture cost and improves the incunabulum yield of each, thereby improving economic benefits and social benefits of sericiculture and being suitable for development of the modern sericiculture industry.

The invention belongs to the field of biomedical materials, and particularly discloses an alginic acid-chitosan composite fiber for tranma repairing and a preparation method thereof. The alginic acid-chitosan composite fiber for the tranma repairing is characterized by comprising an alginic acid component of which the mass fraction is 50-95%, and a chitosan component of which the mass fraction is 5-50%. The processing technique disclosed by the invention is not involved with an organic reagent or an organic chemical reaction, so that the preparation method is mild in reaction system and controllable in condition; the residue problems of a toxic crosslinking agent or an assistant and the like do not exist; used materials, reagents and the like have good biosecurity; the security risk of clinical applications is greatly reduced. In addition, the technology disclosed by the invention is simple and controllable, and has the good product transformation feasibility; the difficulty of risk management in the preparation process is greatly reduced.

The invention provides a production method of a cellulose non-woven fabric with functions of mildew proofing, antibiosis and deodorization through wet-type meltbrown, comprising the following steps of: adding natural chitosan macromolecules subjected to functionalized modification and nanocrystallization into a size prepared from pulp and N-methylmorpholine N-oxide (short for NMMO) to be mixed and dissolved to form a dope; then spraying the dope from a spinning nozzle in a meltbrown way to form a non-woven fabric silk net, and carrying out water mist solidification and regeneration; and finally, washing with water, rolling with a squirt cut, drying, rolling and carrying out other procedures to obtain a natural cellulose non-woven fabric with functions of mildew proofing, antibiosis and deodorization and a continuous filament form. The cellulose non-woven fabric with functions of mildew proofing, antibiosis and deodorization can be applied to wiping textiles, medical consumables, filtering materials, biotechnical materials, photoelectric wafers and the like with functions of mildew proofing, antibiosis and deodorization.

The invention relates to a medical rubbish bin dumping device which is characterized in that the medical rubbish bin dumping device comprises a fixing frame, a support shaft supported at the upper end of the fixing frame, and a slowdown motor which is installed at one lateral end of the fixing frame and is in transmission connection with the support shaft. An overturning box consisting of a bottom support part, a left support part, a right support part and a back support part is arranged inside the fixing frame; clamping devices are arranged at the upper ends of the left and right support parts; and the part of the back support part, which is close to the upper end, is fixedly connected with the support shaft. The medical rubbish bin dumping device realizes automatic dumping of the medical rubbish, and an operator only needs to mount a medical rubbish bin on the medical rubbish bin dumping device and then demount the emptied medical rubbish bin from the dumping device. Compared with the conventional manual dumping manner, the medical rubbish bin dumping device has the advantages of lightening the work intensity, and improving the dumping efficiency. Moreover, in the dumping process, the operator can be far away from the medical rubbish bin, so direct contact between the operator and the medical rubbish is avoided. Therefore, the medical rubbish bin dumping device is safe and hygienic, and reduces the probability of iatrogenic infection of the operator.

The invention discloses a drug-delivery absorbable hemostatic sponge, which belongs to the technical field of novel hemostatic materials and comprises drug-loaded chitosan microsphere and collagen protein, wherein the drug-loaded chitosan microsphere comprises medicinal grade chitosan and medicinal grade tranexamic acid. The weight ratios of the medicinal grade chitosan to the medicinal grade tranexamic acid are (0.01-100):1 respectively. The invention also discloses a method for preparing the drug-delivery absorbable hemostatic sponge. By selecting collagen with good hemostatic function and biocompatibility as the main hemostatic substrate, compounding the drug-delivery chitosan microsphere and the medicinal grade tranexamic acid, and making use of the special properties of the chitosan including hemostatic function and drug-delivery function, a novel hemostatic sponge with rapid hemostasis and lasting and steady drug delivery in a period of time can be prepared, and has considerable economic and social benefits.

The invention provides a handheld eyelid massager, which is used for massaging the eye part of a user and comprises a handheld part, a fixing part, a driving component, a massage component and a switch, wherein the driving component is arranged on the fixing part, the massage component is arranged corresponding to the eye part and is used for massaging the eye part through being driven by the driving component, the switch is used for starting or stopping the operation of the driving component, the massage component comprises an upper eyelid massage element corresponding to the upper eyelid of the eye part and a lower eyelid massage element corresponding to the lower eyelid, the driving part drives the upper eyelid massage element to repeatedly do extruding massage movement on the upper eyelid from upper positions to lower positions, and simultaneously drives the lower eyelid massage element to repeatedly do extruding massage movement on the lower eyelid from lower positions to upper positions, targeted massage is carried out on the upper eyelid and the lower eyelid of the user, and the pressure increase mode is used for discharging out thick secreta in the meibomian glands, so the blockage of the meibomian glands is eliminated, the goal of prompting the smooth secretion of the meibomian glands can be achieved, through the handheld design, a better positioning effect can be realized by the user, and in addition, the positions can be freely regulated according to the massage force intensity.

The invention relates to washable negative pressure drainage dressing which comprises a sponge body, a drainage catheter and a washing catheter, wherein a double-cavity catheter is inserted in the sponge body, a plurality of through holes are evenly arranged on the wall of the double-cavity catheter inserted in the sponge body, and the outer end of the double-cavity catheter is connected with the drainage catheter and the washing catheter through a tee joint. A washing cavity channel and a drainage cavity channel are arranged in the double-cavity catheter. According to the washable negative pressure drainage dressing, the medical sponge body can be repeatedly washed in the treatment process, so that phenomena such as unsmooth drainage caused by drying and blocking of the sponge body in the wound negative pressure treating process are avoided. The washable negative pressure drainage dressing is reasonable in structure and convenient to operate and use, and reduces dressing change times and risk of clinical infection. In addition, the clinical operation is safe and convenient.

The invention provides a microbial deodorant and strain for eliminating waste odor of municipal landfill and waste transfer station, and the preparation and application method thereof. The preparation method comprises the following steps: culturing Saccharomyces cerevisiae with the conservation number of CGMCC No.5183 in a PDA culture medium, and culturing Lactobacillus casei (CGMCC No.5182) in an MRS culture medium to obtain the seed liquid; and fermenting in a fermentation tank to obtain the microbial deodorant. The microbial deodorant is prepared by a mixed culture manner so as to lower the fermentation cost, reduce the generation of mixed bacteria and stabilize the product quality. The microbial deodorant prepared by the method can effectively eliminate the waste odor of the municipallandfill so as to achieve good deodorant effect.

The present invention relates to biodegradable antibacterial composite fibers, which comprise polylactic acid, nanoparticles and a surfactant, wherein the nanoparticles are nanometer zinc oxide or nanometer titanium oxide, and a weight ratio of the polylactic acid to the nanoparticles to the surfactant is 100:2-10:0.08-1.2. The present invention further provides a preparation method of the biodegradable antibacterial composite fibers, wherein the preparation method comprises a polylactic acid solution preparation step. The preparation method specifically comprises: dissolving polylactic acid in a mixed solvent, wherein the polylactic acid concentration is 10-15 g / L; adding nanoparticles and a surfactant to the polylactic acid solution, and completely mixing to form a mixed solution; carrying out an ultrasonic dispersion treatment on the mixed solution; and placing the stable suspension solution after being subjected to the ultrasonic dispersion treatment in a preset syringe, and carrying out a spinning treatment on the suspension solution according to the preset injection speed. According to the present invention, the preparation method is simple and feasible, and the prepared composite fibers have a certain strength, good biological safety, and good antibacterial property.

The invention provides an eyelid massager which comprises a binding part used for being bound with the head of a user, a fixing part arranged at the front end of the binding part, a driving part installed on the fixing part in a rotation mode, a massaging part arranged by corresponding to the eyes, connected with the driving part and used for massaging the eyes under the drive of the driving part and a switch used for starting or stopping the driving part. The massaging part comprises upper eyelid massaging balls corresponding to the upper eyelids of the eyes and lower eyelid massaging balls corresponding to the lower eyelids of the eyes. The driving part is used for driving the upper eyelid massaging balls to extrude and massage the upper eyelids from top to bottom repeatedly and at the same time, driving the lower eyelid massaging balls to extrude and massage the lower eyelids from bottom to top repeatedly. The upper eyelids and the lower eyelids of the user are massaged specifically. The manner of increasing the pressure is used for discharging thick and dense secreta in the meibomian glands so as to eliminate jamming of the meibomian glands and achieve the aim of promoting smooth secretion of the meibomian glands.

The invention discloses a flow guide device, which contains a first multilayer flow deflector with inner and outboard connection points and a second multilayer flow deflector with inner and outboard connection points. The inner and outboard connection points of the first multilayer flow deflector are respectively connected with first inner and outboard connecting lines. The inner and outboard connection points of the second multilayer flow deflector are respectively connected with second inner and outboard connecting lines. When the flow guide device is placed in a photobioreactor for diversion, the first multilayer flow deflector and the second multilayer flow deflector form predetermined angles of inclination relative to the horizontal direction by pulling upwards the first outboard connecting line and the second outboard connecting line or by putting down the first inner connecting line and the second inner connecting line. The inclination angles of the flow deflectors can be properly adjusted according to the sunlight frequencies required during different culture periods of photosynthetic microbes. In addition, the flow guide device is convenient to clean, therefore avoiding problems such as bacterial infection caused by incomplete cleaning.

The invention discloses a community epidemic prevention management system linked with face recognition and temperature measurement access control. Master control module, the main control module is coupled with a registration module, a detection module, an alarm module, a data management module and a community management module; the registration module is used for real-name identity verification registration of community residents, the detection module is used for face recognition and temperature measurement of the community residents, and the community management module is used for community managers to master community epidemic situations at the first time and reasonably control communities at the first time according to the epidemic situations. According to the invention, the face recognition module and the body temperature detection module are arranged; according to the invention, residents can be identified and detected by themselves and can be used day and night, the work intensity of community workers is reduced, the infection risk is reduced, the alarm module is arranged to prompt and alarm the residents with abnormal body temperature, suspected cases can be screened out inadvance, and the infection probability of other people is greatly reduced.

The invention discloses a preparation process of a wound dressing, which is characterized by comprising the steps of: with a first polyurethane elastic film as a base cloth, coating hydrogel on the first polyurethane elastic film; and then adhering a second polyurethane elastic film on the coating end face of the hydrogel by using a coiling device to form a composite layer body. The preparation process of the wound dressing can be used for preparing the wound dressing meeting the use requirements of multiple wounds, can also be used for preparing the wound dressing with the functions of keeping a wound healing environment, shortening healing time, resisting bacteria and reducing infection chances, is rapid, and accords with the industrial production requirements.

The invention discloses an antimicrobial coated resin lens and a manufacturing method thereof. The manufacturing method of the antimicrobial coated resin lens is characterized by including steps: 1, manufacturing a wear-resistant hardening layer on the surface of a resin lens by adopting dip-coating technology; 2, plating an antireflection film layer on the surface of the wear-resistant hardening layer by adopting vacuum sputtering coating technology and ion source assisted coating technology; 3, plating an antimicrobial layer on the surface of the antireflection film layer by adopting the vacuum sputtering coating technology and the ion source assisted coating technology; 4, plating an adhesive layer on the surface of the antimicrobial layer by adopting the vacuum sputtering coating technology and the ion source assisted coating technology; 5, continuing adopting the vacuum sputtering coating technology for plating a top wear-resistant layer on the surface of the adhesive layer. The manufacturing method of the antimicrobial coated resin lens adopts the vacuum sputtering coating technology and the ion source assisted coating technology, and thereby increases adhesion stress among all the film layers, and achieves the purpose of enabling obtained glasses products to not only keep original performance of the antireflection film layer, but also have long-term effective excellent antibacterial performance.