The invention provides compound medicine for treating difficult-to-heal wounds, multiple wounds and suppurative diseases. The medicine mainly comprises ascorbic acid, riboflavin, resina draconis, jaggery, erythrocin, pseudo-ginseng and borneol, and is prepared into medicine powder, an unguent and liquid medicine by adopting the method, wherein the medicine powder is mainly used for treating the multiple wounds such as a knife wound, a scald, a lacerated wound, an explosive wound, nipple rupture, crush wounds on hands and feet, and a wound that wood, bamboo and iron nails pierce into muscles and bones, and the suppurative diseases such as an abscess, an ulcer, phlegmon and multiple furuncles, carbuncles and malignant boils; the unguent is mainly used for treating various traumatic injuries, pruritus cutanea and mosquito bite injuries, and can relieve pains caused by symptoms such as a lumbar pain, a cervical vertebra pain, scapulohumeral periarthritis and wrist and ankle pains effectively; and the liquid medicine is mainly used for disinfecting the multiple wounds such as the abscess, the ulcer and the knife wound and removing pollutants, and can accelerate wound healing effectively. The medicine can treat the disease symptoms uniformly, and is instant in effectiveness, short in treatment course and low in expense; an effective ratio is 100%; a curative ratio is 98%; and a healing effect is remarkable.