647 results about "Peritoneal membrane" patented technology

The invention provides an evaluation method for gastric cancer peritoneal metastasis state recognition and PCI score estimation, and the method comprises the steps: receiving a preoperative abdominal enhancement CT image, and carrying out the automatic positioning preprocessing of the peritoneum through resampling, normalization, image enhancement and a region attention mechanism; image omics features are extracted from the region of interest and fused with the depth features of the multi-scale convolutional neural network, and a binary classification model based on a residual network / Transform is constructed to output transition state probability and confidence; pCI scores of all the areas are quantitatively evaluated synchronously through the peritoneal thirteen subareas, and finally a transfer prediction result, a PCI spatial distribution map, a visual heat map and a model interpretation report are integrated to form structured diagnosis output. According to the method, transition state identification and PCI score quantification can be realized, and the problems of single function, weak generalization, low interpretability and the like of a traditional model are solved.

The invention relates to the technical field of medical information processing, and discloses an AI-based peritoneal dialysis state prediction system, which comprises a data acquisition module used for acquiring medical data of a peritoneal dialysis patient; the data preprocessing module is used for carrying out missing value processing on the collected medical data by adopting KNN interpolation and STL decomposition, and carrying out feature extraction through sliding window analysis to obtain target feature data; the dialysis state prediction module is used for inputting the target feature data into the ResNet-Transformer-GRU model and outputting a dialysis state prediction result; the generation module is used for generating personalized dialysis scheme adjustment suggestions by adopting a multi-target particle swarm optimization algorithm based on the dialysis state prediction result; the visualization module is used for visually displaying the dialysis state prediction result and the personalized dialysis scheme adjustment suggestion to medical staff; through automatic data acquisition, processing and prediction, manual operation of medical staff is reduced, and time and energy are saved.

The invention relates to an automatic peritoneal dialysis machine auxiliary system capable of preventing peritoneal protein from being lost, and belongs to the technical field of peritoneal dialysis. By arranging the auxiliary system comprising a hollow fiber membrane filter, peritoneal drainage liquid is guided into the hollow fiber membrane filter in the drainage stage; the protein is intercepted by utilizing the semi-permeable membrane characteristic, and small molecule metabolic wastes penetrate through the semi-permeable membrane characteristic to form a filtrate rich in the protein; and then the feedback pump speed is dynamically adjusted through a control system based on a signal of a flow sensor, so that the feedback process of the protein liquid is stably synchronized with drainage, liquid injection and staying stages of the automatic peritoneal dialysis machine, online recovery and safe feedback of protein are realized, and the problem that the protein liquid flows back to the treatment cycle of the automatic peritoneal dialysis machine is solved on the premise that the treatment cycle is coordinated with the treatment cycle of the automatic peritoneal dialysis machine. Protein in peritoneal drainage liquid is continuously and selectively recovered and safely returned, so that the problem of protein trophism loss of long-term peritoneal dialysis patients is directly reduced.

Systems and methods for infection prevention and treatment in biological conduits using electroporation or pulsed field ablation (PFA). The system includes an elongate member, such as a dialysis catheter, vascular access device, or peritoneal dialysis conduit, with at least one electrode positioned along, within, or around the member. A control unit applies pulsed electric fields to inhibit microbial colonization, disrupt bacterial biofilms, and alter permeability of bacterial or endothelial cells to enhance sterility or fluid exchange. The system may use real-time impedance monitoring, microbial detection, or fluid composition analysis to adjust electroporation parameters. Electroporation may synchronize with dialysis cycles or antimicrobial lock solutions. The method includes automated, clinician-controlled, or sensor-triggered treatments to reduce infections and improve device longevity. The system provides an alternative or augment to antibiotics, reducing the risk of drug-resistant infections while improving the longevity and safety of medical implants.

The invention discloses an intestinal anastomosis operation abdominal cavity film covering structure, and relates to the technical field of intraoperative film covering, the intestinal anastomosis operation abdominal cavity film covering structure comprises an external connection part, an internal expansion part and an adsorption part, through inflation of an outer pipe, transverse branch pipes and vertical branch pipes of a corrugated pipe structure extend, transverse concave bases and vertical concave bases are far away from each other, and meanwhile transverse folding frames and vertical folding frames are unfolded; a pull wire of the negative pressure assembly can be pulled in the unfolding process of the transverse folding frame and the vertical folding frame, so that the fragment connected with the pull wire is pulled up, the fragment forms negative pressure at the peritoneum position through the connecting film, and the lower film is attached to the peritoneum and the unfolding position of an operator; the unfolding effect is achieved through inflation, meanwhile, the prominent effect of adsorbing the covered position is achieved, the intestinal canal incision operation is carried out on the upper side of the upper film, and the pollution of the intestinal canal is received.

This disclosure relates to systems for medical fluid pumps and related methods. In some implementations, a system includes a system for draining fluid from a peritoneal cavity of a patient comprising a microfluidic pump; a drain bag fluidly coupled to the microfluidic pump; and an inlet line coupled to the drain bag, wherein the microfluidic pump is configured to apply a negative pressure to an interior of the drain bag to draw effluent from a peritoneal cavity of the patient along the inlet line and into the drain bag. In some implementations, a system for performing peritoneal dialysis includes a microfluidic pump; a dual chamber bag fluidly coupled to the microfluidic pump, where the dual chamber bag includes an effluent chamber configured to be fluidly coupled to a peritoneal cavity of a patient; a dialysate chamber; and a flexible membrane separating the effluent chamber from the dialysate chamber.

The invention discloses a peritoneal dialysis system which comprises an abdominal cavity pipeline with the first end communicated with the abdominal cavity of a human body; the semi-permeable membrane assembly comprises a membrane, a first side and a second side, the first side and the second side are separated by the membrane, and the first side is communicated with the second end of the abdominal cavity pipeline so as to receive the abdominal cavity dialysate from the abdominal cavity pipeline and inject the abdominal cavity dialysate into the abdominal cavity of the human body; the external liquid path system comprises an external liquid pipeline communicated with the second side, and the external liquid pipeline comprises a waste liquid outlet for outputting dialysis waste liquid led out from the peritoneal dialysis liquid through the membrane; when the peritoneal dialysis solution is led out, the membrane allows moisture and small molecular solutes in the peritoneal dialysis solution to permeate into the second side and entraps a macromolecular penetrant on the first side so as to maintain the osmotic pressure of the peritoneal dialysis solution.

The invention discloses a movable assistor for peritoneal dialysis, and relates to the technical field of peritoneal dialysis. The movable assistor for peritoneal dialysis comprises a bottom plate, a fixing rod is fixedly arranged on the top face of the bottom plate, the outer wall of the fixing rod is slidably sleeved with a lifting sleeve, a plurality of self-locking wheels are fixedly arranged on the bottom face of the bottom plate, and a lifting mechanism, a dialysis mechanism, a placing mechanism and a fixing mechanism are arranged above the bottom plate. The dialysis mechanism has the technical effects that the dialysis mechanism is composed of the monitoring part and the control part, an automatic monitoring and intelligent control system for the dialysis process is formed, two tray scales of the monitoring part can monitor the weight change of a dialysate container in real time, and the weight information is transmitted to the control calculator through a second data line; the two intelligent flow monitoring valves are installed at the bottom of the connecting pipe and can monitor the flow of dialysate in real time and transmit data through the first data line, and the calculator is controlled to analyze and process the received weight and flow information.

The present application relates to a kind of peritoneal dialysis catheter fixing auxiliary device, including the bottom plate for shielding stoma and the bandage for fixing bottom plate on patient's body, first through-hole for dialysis tube to pass through is opened in the thickness direction on the bottom plate, sleeve is mounted in the first through-hole, one end of the sleeve is communicated with first through-hole, the other end extends downward;Rotary fit has cover plate above the bottom plate, the bottom surface of the cover plate is sealed with the top surface of bottom plate, second through-hole is opened in the thickness direction on the cover plate, the first through-hole is located on the rotation track of second through-hole.This technical solution, by setting sleeve, can avoid stoma healing during interval, without using special dialysis tube daily care tool, effectively reduce the discomfort of patient's daily life, and can adjust the opening and closing state of stoma, facilitate medical staff operation.

The present disclosure relates to a transplantable cell therapy product composition for diabetes mellitus that contains an aggregate of insulin-secreting cells derived from stem cells. In the present disclosure, an NF microwell array membrane was fabricated by applying a molding process to an electrospun, permeable, biodegradable polycaprolactone (PCL) NF membrane and thus allows gases and soluble factors to permeate therethrough. The NF microwell of the present disclosure could provide more nutrients to the iPSC aggregates than conventional impermeable PDMS microwells, thus enhancing survival and differentiation capabilities of the cells. Additionally, the NF membrane was attached singly to the subcutaneous tissue and to the surface of organs such as liver and peritoneum without the need for a fixing material or separate sutures and was integrated with surrounding tissues, resulting in higher insulin secretion than PDMS microwells. Therefore, the present disclosure can be effectively utilized as a composition for the prevention or treatment of diabetes.

The present disclosure generally relates to systems and methods of use for draining cerebrospinal fluid (CSF) from a brain or a spinal canal in a subject, for example, to treat hydrocephalus or other conditions. In some embodiments, the disclosure relates to a device comprising a flow controller positioned within a conduit that allows CSF to flow through the conduit from a first end to a second end. This may allow the CSF to drain, for example, from an intradural space (such as a thecal sac) into, for example, a paraspinal space, paraspinal vein or other venous space, or peritoneal cavity. A variety of methods may be used to hold or anchor the device in place, for example, an expansion apparatus. In some embodiments, the device can be implanted percutaneously at a location along or within a subject's spinal column, thus reducing the need for surgery, general anesthesia, and hospitalizations.

Damping devices, including damping devices for automated peritoneal dialysis (APD) systems, and associated systems, devices, and methods are disclosed herein. In one embodiment, a damping device includes a body portion, a first membrane, and a second membrane. The body portion can include a first side, a second side opposite the first side, an inlet, and a cavity fluidly coupled to the inlet. The cavity can be defined at least in part by a lumen in the body portion extending from the first side to the second side. The first membrane can be affixed to the first side of the body portion such that the first membrane hermetically seals the cavity at the first side. The second membrane can be affixed to the second side of the body portion such that the second membrane hermetically seals the cavity at the second side.

The utility model relates to a peritoneal dialysis tube disinfection device which comprises a disinfection tank and a tank cover detachably connected with the disinfection tank, the tank cover is provided with a tube placing hole allowing a tube body of a peritoneal dialysis tube connected with a human body to penetrate through, so that a first end, far away from the human body, of the peritoneal dialysis tube can vertically enter an inner cavity of a tank body in the disinfection tank in the axial direction under the action of gravity; the bottom face of the inner cavity of the tank body is provided with a limiting step axially aligned with the pipe containing hole, so that the first end can be kept on the limiting step in a clamped connection mode. The disinfection tank is designed for the titanium alloy end of the peritoneal dialysis catheter, so that the end can be ensured to be completely immersed into disinfectant in the disinfection tank under the action of gravity, and the pollution risk of the external environment to the peritoneal dialysis catheter is reduced. In addition, due to the design of the limiting step, it is ensured that the end is kept at the stable position in the disinfection process, the end is prevented from shaking or shifting in the disinfection tank, and the titanium alloy end is prevented from being physically damaged due to collision.

In some examples, a sensor for detecting dextrose includes at least one working electrode including Cu and being configured to electro-oxidize dextrose in an aqueous solution. The sensor further includes at least one counter electrode. In some examples, a system includes a fluid line, a dextrose container, a peritoneal dialysis container, and the sensor. The fluid line is configured to transport water. The dextrose container is configured to introduce dextrose in the fluid line to generate a peritoneal dialysis composition comprising the water and dextrose. The peritoneal dialysis container is downstream of the dextrose container and configured to receive the peritoneal dialysis composition. The sensor may be configured to detect dextrose in the peritoneal dialysis composition.

A leak detecting apparatus (1) for detecting a leak and determining the size of the leak in a suture repaired site (5) of a hollow organ (3), for example, a stomach, in a cavity (7), for example, the peritoneal cavity of a subject comprises a first insufflator (12) for insufflating the hollow organ (3) with a first gas, and a second insufflator (14) for insufflating the cavity (7) with a second gas. A gas detector (18) is provided for detecting the concentration of the first gas in gases exhausted from the cavity (7) through a communicating conduit (35). A flow meter (25) monitors the flow rate of the first gas to the hollow organ (3). First and second pressure sensors (15) and (16) monitor the static pressure of the first and second gases in the hollow organ (3) and the cavity (7), respectively. The apparatus (1) is operable in a first mode and a second mode. In both the first and second modes of operation a microprocessor (50) controls the second insufflator (14) for maintaining the pressure in the cavity (7) at a relatively low predefined pressure, and the first insufflator (12) for maintaining a constant predefined pressure differential between the pressures in the hollow organ (3) and the cavity (7) of approximately 7 mmHg. In the first mode the microprocessor (50) determines the size of the leak as a function of the pressure differential and the concentration of the first gas in the exhaust gases. In the second mode of operation the microprocessor (50) determines the size of the leak as a function of the pressure differential and the flow rate of the first gas to the hollow organ (3) with the hollow organ (3) sealed apart from the sutured site (5).

A method of performing peritoneal dialysis (PD), the method comprising: delivering a PD fluid to the peritoneal cavity of a patient through a PD catheter; dwelling the PD fluid within the peritoneal cavity; and while dwelling the PD fluid, removing a biofilm from the PD catheter wall using a biofilm removing solution. The biofilm removing solution comprises: sodium citrate dihydrate; citric acid anhydrous; sodium lauryl sulfate; and water. In another aspect, a method for decontaminating a peritoneal dialysis (PD) catheter and removing a biofilm from the PD catheter and a transfer set, the method comprising: providing a biofilm removing solution; transferring the biofilm removing solution into a syringe; connecting the syringe to a transfer set of the PD catheter; and filling the transfer set and the PD catheter with the biofilm removing solution.

The utility model relates to the technical field of peritoneal dialysis, and provides a consumable box connecting piece and peritoneal dialysis equipment. The consumable box connecting piece is used for installing a consumable box, an elastic arm capable of being opened and closed is arranged on the side face of the consumable box, a limiting boss is formed on the elastic arm, the elastic arm is suitable for driving the limiting boss to be close to or away from the consumable box, the consumable box connecting piece comprises a connecting piece body, and an installing groove used for fixing the consumable box is formed in the connecting piece body. A limiting hole is formed in the side face, facing the elastic arm, of the mounting groove, and the limiting hole of the mounting groove is used for being connected with a limiting boss of the consumable box in a clamped mode. According to the consumable box connecting piece, the fixing effect of the consumable box can be enhanced, and the consumable box is prevented from loosening or falling off.

A medical fluid system includes a medical fluid pump actuator; a medical fluid carrying set including a flexible sheet; a temperature sensor positioned and arranged to sense a temperature of the medical fluid flowing through the medical fluid carrying set; a pressure sensor positioned and arranged to contact the flexible sheet when the medical fluid carrying set is loaded for operation with the medical fluid pump actuator; and a control unit configured to (i) precondition the flexible sheet for operation with the pressure sensor by causing the medical fluid pump actuator to apply pressure to the flexible sheet and (ii) use an output from the temperature sensor in a compensation algorithm that modifies an output from the pressure sensor.

This utility model relates to the field of packaging and sealing technology, and discloses a peritoneal dialysis fluid packaging and sealing machine, including a support plate. A slide rail is fixedly connected to the upper surface of the support plate, and a slider is fixedly connected to the upper surface of the slide rail. A clamping assembly is provided outside the slider, the clamping assembly including a clamping plate. The clamping plate is disposed outside the slider, and a connecting rod two is fixedly connected to the outer wall of the clamping plate. A fixing post one is rotatably connected to one end of the outer wall of the connecting rod two, and a fixing post two is rotatably connected to one end of the connecting rod two. A connecting rod three is rotatably connected to the outer wall of the fixing post one. In this utility model, the clamping plate stably clamps the packaging bag by driving the gears and connecting rods through a motor. Combined with the sliding of the slider on the slide rail, the packaging bag can be accurately transported to the sealing position, improving the stability of clamping and transporting, ensuring accurate positioning of the packaging bag during the sealing process, reducing sealing deviations caused by displacement, and improving sealing quality.

The present disclosure sets forth an automated peritoneal dialysis (“PD”) system, which enables the re-use of certain disposable components. The APD system includes a sterilization source, such as a steamer or a UV radiation light source that sterilizes a disposable filter. During therapy, the disposable filter is connected to a PD fluid line and to a patient's catheter. Post-therapy, the disposable filter is disconnected from the patient's catheter, but remains connected to the PD fluid line, and the disposable filter undergoes steam or UV radiation sterilization.

The utility model relates to the technical field of peritoneal dialysis equipment, and discloses a pipeline speed controller which comprises a lower clamping plate and an upper clamping plate, a peritoneal dialysis pipeline body is arranged between the lower clamping plate and the upper clamping plate in a clamped mode, and a plurality of clamping mechanisms are arranged on the two sides of the lower clamping plate and the two sides of the upper clamping plate in a clamped mode. A pipeline flow speed control mechanism is fixedly arranged on the upper end face of the upper clamping plate, and first handles are arranged on the two sides of the lower clamping plate correspondingly. According to the peritoneal dialysis catheter, the catheter flow speed control mechanism is arranged at the upper end of the upper clamping plate, the baffle can compress the peritoneal dialysis catheter body by rotating the rotating handle, and therefore the purpose of controlling the flow speed of dialysate in the peritoneal dialysis catheter body is achieved, and meanwhile the upper clamping plate and the lower clamping plate are clamped and positioned through the limiting rod and the limiting hole; the upper clamping plate and the lower clamping plate can be detached by detaching the clamping mechanism after dialysis is completed, so that the pipeline speed controller can be repeatedly used, and the dialysis cost is reduced.

1. Name of the product in this design: Disposable kit for peritoneal dialysis devices. 2. Purpose of this design: This product is a disposable kit for peritoneal dialysis devices. 3. The key design points of this product are: Design 1 focuses on the combination of color and shape, and Design 2 focuses on the shape of the product. 4. The picture or photo that best illustrates the key design points: Design 1 3D diagram 1. 5. Design 1 is designated as the basic design. 6. Other situations requiring explanation: Design 1 requests color protection.

An automatic pump-based fluid management system as described herein includes an intercostal pump, which is typically a resilient, flexible tube having an inlet and an outlet. The inlet is attached to a first tube that extends from the intercostal pump to a first region of a patient's body, such as the patient's pleural cavity. The outlet is connected to a second tube that extends from the intercostal pump to a second region of the patient's body, such as the patient's peritoneal cavity. During use, the intercostal pump is positioned between a first and second rib of the patient. The intercostal pump operates by continuously compressing and decompressing the space between the first and second ribs during the patient's breathing.

Pressure sensors, including pressure sensors for automated peritoneal dialysis (APD) systems, and associated systems, devices, and methods are disclosed herein. In one embodiment, an APD system includes a diaphragm positioned over an opening in a disposable set that includes one or more fluid lines. The diaphragm is affixed to the disposable set about a periphery of the opening. The APD system further includes a pressure sensor configured to measure a pressure of fluid flowing through the disposable set. The pressure sensor includes a load cell and an indenter. The indenter can be moveable along an axis such that, when the diaphragm is aligned with the axis, a convexly curved surface of the indenter can be positioned against the diaphragm. When the indenter is contacting the diaphragm, the load cell can measure a force applied to the load cell by the diaphragm and / or by the fluid flowing through the disposable set.

The invention relates to the technical field of peritoneal dialysis monitoring, and discloses a dynamic weighing and data fusion peritoneal dialysis solution balance monitoring system and method. The system comprises a dynamic weighing module, a multi-source data acquisition module, a data fusion processing module, a balance monitoring module and an early warning output module. The dynamic weighing module collects dialysate input and discharge amount in real time and generates weight data; the multi-source data acquisition module is used for acquiring dialysate components, treatment time and physiological parameters of a patient; the data fusion processing module is used for fusing the data to generate dialysate balance characteristic data; the balance monitoring module is used for calculating the net ultrafiltration amount and the liquid balance state and identifying the risk of abnormal leakage or liquid retention; and the early warning output module generates early warning information when the risk is identified. The system does not need manual intervention, can collect and fuse multi-source data in real time, accurately judge the liquid balance state and give an early warning in time, and is suitable for hospital and home peritoneal dialysis scenes.

A proportioning system includes a solute container filled with dry solutes, a source of water, a container of electrolyte concentrate, a fluid circuit connecting the solute container to the source of water and the container of electrolyte concentrate, the fluid circuit having an empty mixing container, a controller configured to transfer water from the source of water to the solute container through the fluid circuit so as to prepare a solute concentrate solution in the solute container. The controller is configured to transfer fluid from the container of electrolyte concentrate to a mixing container as well as a solute concentrate from the solute container to the mixing container and further adding water to said mixing container to form a medicament therein.

A device for safely and effectively disinfecting a catheter while it remains implanted in a patient's body is provided. [Solution] Methods and devices for providing therapeutic electromagnetic radiation (EMR) to inactivate infectious agents and / or enhance healthy cell growth in, on, or around a catheter (10) placed in a patient's body cavity. Non-ultraviolet therapeutic EMR is transmitted axially along the lumen of the catheter body and / or along an optical element (14) within the catheter body. Delivery of the therapeutic EMR to specific infected areas and / or areas requiring tissue healing results in inactivation of primary sources of infection in, on, and around the catheter and / or enhancement of healthy cell growth around the catheter through the use of controlled relative intensity and treatment-site-specific dose projection of the therapeutic EMR radially emitted from the optical element. Specific embodiments for urinary catheters and peritoneal dialysis catheters are also disclosed.

A peritoneal dialysis (“PD”) system includes a PD fluid pump, a PD fluid heater positioned and arranged to heat fresh PD fluid pumped by the PD fluid pump, and a phase change material (“PCM”) device positioned and arranged to receive fresh PD fluid heated by the PD fluid heater. The PCM device includes a PCM having a melting temperature selected so that the PCM solidifies when underheated fresh PD fluid contacts the PCM transferring heat to the underheated fresh PD fluid. Alternatively or additionally, the PD system may include a different PCM device having a PCM with a melting temperature selected so that the PCM melts when overheated fresh PD fluid contacts the PCM thereby removing heat from the overheated fresh PD fluid. A configuration for the PCM device is also disclosed.