The invention relates to the technical field of an electric spindle, in particular to a high-speed precise electric spindle cooling system which comprises an electric spindle shell cooling part, an electric spindle core cooling part and a bearing spindle core lubricating/cooling part, wherein when the electric spindle works, the temperature rise change can be controlled within +/-1 DEG C. The concrete scheme is as follows: a ring sleeve type heat pipe cooling mode is arranged at the electric spindle shell part, and the heat of the shell is taken away quickly by increasing the cooling contact surface; the spindle core cooling part is provided with symmetrical bar-type heat pipes which are uniformly distributed on the spindle core, and the spindle core is cooled by use of the high-speed conductivity and homoiothermy of the heat pipes; and a spindle core liquid lubricating/cooling mode is adopted at the bearing lubricating/cooling part, and makes full use of the high rotation speed of the high-speed electric spindle to generate centrifugal force so that the lubricating/cooling liquid is uniformly distributed on the bearing roller. The temperature stability of the electric spindle can be ensured, the processing precision error caused by thermal expansion of the electric spindle is minimized, and the service life of the spindle and the spindle bearing can be prolonged at the same time.