Artificial pancreas closed-loop control algorithm

A controller and control signal technology, applied in the field of artificial pancreas, which can solve the problems of inaccuracy, insulin transport, absorption speed limitation, artificial pancreas delay, etc.

Active Publication Date: 2018-07-10
MEDTRUM TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the effect of infusion varies according to the specific conditions of different patients and the type of insulin, and the insulin pumps currently on the market are still limited by the speed of delivery and absorption of the insulin they use
Despite major breakthroughs in pump and sensor technology over the years, an artificial pancreas must address delays and inaccuracies in glucose sensors and insulin injections

Method used

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  • Artificial pancreas closed-loop control algorithm

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Embodiment Construction

[0037] In order to achieve the above-mentioned technical objectives and make the features and advantages of the present invention more understandable, various implementation modes of the present invention will be specifically described in conjunction with the following examples.

[0038] combine figure 1 with figure 2 An example of the present invention is given. Such as figure 1 As shown, the patient wears an artificial pancreas consisting of a glucose sensor 1 that continuously measures blood glucose at discrete time intervals and provides corresponding blood glucose measurement data, and an insulin pump 2 that responds to infusion control signals and infuses insulin. There is a handset 3 in which the processor acts as a controller to carry out the steps of the method of the invention at each of a plurality of discrete time intervals.

[0039] combine figure 2 explain figure 1 An implementation of each component in the method of the present invention. In this embodim...

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Abstract

The invention provides an artificial pancreas closed-loop control algorithm and artificial pancreas using the method. The method mainly comprises the following steps: constructing an autoregressive model that an insulin absorption delay factor is actively introduced; calculating required insulin infusion amounts respectively via the autoregressive model and a PID algorithm; and implementing loop optimization of parameters of the two insulin infusion amounts via an average value of calculation results of the two insulin infusion amounts, so as to offer more accurate blood glucose trend prediction and a more appropriate insulin infusion amount.

Description

technical field [0001] The invention relates to an artificial pancreas, in particular to a closed-loop algorithm for controlling insulin infusion by a controller. Background technique [0002] Diabetes is a chronic metabolic disease caused by the inability of the pancreas to produce enough insulin, which reduces the body's ability to metabolize glucose. Recently, substantial improvements in the treatment of diabetes have been achieved through the development of insulin infusion devices that relieve patients of the need for multiple daily injections of insulin via syringe or insulin. Insulin infusion devices can achieve insulin infusion in a manner that is more similar to natural physiological processes, and can control insulin infusion devices to give patients better blood sugar control with standard programs or personalized adjustment programs. Furthermore, the insulin infusion device may be an implantable device for subcutaneous infusion or as an external device with an i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M5/20
CPCA61M5/20A61M2230/201A61M2230/005A61M5/14244
Inventor 杨翠军
Owner MEDTRUM TECH
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