48 results about "Tendonitis" patented technology

This invention provides for using a locally delivered low dose of a corticosteroid to treat pain caused by any inflammatory disease including sciatica, herniated disc, stenosis, mylopathy, low back pain, facet pain, osteoarthritis, rheumatoid arthritis, osteolysis, tendonitis, carpal tunnel syndrome, or tarsal tunnel syndrome. More specifically, a locally delivered low dose of a corticosteroid can be released into the epidural space, perineural space, or the foramenal space at or near the site of a patient's pain by a drug pump or a biodegradable drug depot.

A low cost foldable orthosis for the treatment of foot and ankle conditions including plantar facitis and tendonitis, the orthosis is a foldable molded portion manufactured in a variety of incremental sizes, having a generally U-shaped cross-sectional configuration and a flat foot bed, interconnected by a hinge. This device includes a variety of spacers which enable the angle of covered by a soft fabric covering, and using a removable and interchangeable foot bed wedge insert permitting the angle of dorsiflexion, plantar flexion, inversion and eversion to be varied.

Provided are methods for enhancing exercise (e.g., intense, eccentric, elevated temperature, repetitive, aerobic, and high altitude) performance, comprising administering electrokinetically-altered aqueous fluids comprising an ionic aqueous solution of stably configured charge-stabilized oxygen-containing nanostructures predominantly having an average diameter of less than 100 nanometers. In certain aspects, enhancing exercise performance comprises at least one of: reducing plasma inflammatory cytokines (e.g., IFN-alpha, ENA-78 and BDNF); ameliorating muscle / tendon damage or enhancing muscle / tendon recovery; reducing biomarkers of exercise-induced muscle injury (e.g., CK, plasma myoglobin); ameliorating exercise induced tendinosis, tendonitis, tenosynovitis, avulsion, and tendon strain associated with chronic repetitive movement or enhancing recovering therefrom; increasing VO2 max; decreasing RPE; reducing blood lactate; preserving muscle contractile function (e.g., maximal force, joint ROM); reducing muscle soreness; ameliorating onset of fatigue in an excercising subject. Improved methods for producing electrokinetically altered aqueous fluids (including sports beverages) are also provided.

A device for treatment of plantar fasciitis and / or Achilles tendonitis that comprises:(a) a calf strap removably engagable to the calf of a leg;(b) a foot assembly removably engagable to the foot of the leg such that when the device is worn the assembly can be positioned proximate to the ball of the foot intermediate to the midfoot and forefoot areas of the foot to secure it to the foot; and(c) a substantially inelastic tension member connectable between the calf strap and the foot assembly in a tensioned mannersuch that when the device is worn the plantarflexion of the ankle is limited such that the plantar surface of the foot is held in a neutral to slight dorsiflection.Also, a method of treating plantar fasciitis and / or Achilles tendonitis that comprises applying a such a device so as to maintain the plantar fascia and other structures on the plantar surface of the foot in a neutral to slight dorsiflection.

Provided is an ankle supporter capable of returning the wearer's ankle to a normal position by moving the connective tissue and muscles below the skin following sprain or Achilles tendonitis. The ankle supporter includes a first elastic panel knitted in a belt-like shape on the medial side of the wearer's foot extending from the sole to an area corresponding to the Achilles tendon and having a stretch resistance greater than that of the base fabric and a second elastic panel knitted in a belt-like shape on the medial side of the wearer's foot extending from the heel to the base of the foot top of the wearer to intersect the first elastic panel below the center of the medial ankle and having a stretch resistance greater than that of the base fabric.

The invention relates to a multifunctional drug shoe pad capable of simultaneously carrying out pharmacotherapy, magnetotherapy and phototherapy, belonging to the field of the external application of traditional Chinese medicine. The shoe pad comprises a surface layer, a drug carrying layer and a bottom layer. The shoe pad is characterized in that drugs carried in the drug carrying layer mainly comprise dozens of selected Chinese medicinal herbs such as angelica sinensis, herba epimedii, rhizoma curculiginis, angelica roots, cassia barks, radix sophorae flavescentis, ligusticum wallichii, borneol, camphor, menthol, azone, and the like as well as substances with good physiotherapy effects, such as natural magnetite powder, far infrared ceramic powder, and the like. The invention has the use effect of an ordinary shoe pad and also the disease adjuvant therapy effect which cannot be achieved by the ordinary shoe pad, has good adjuvant therapy effects on various diseases such as headache, dizziness, agrypnia, hypertension, chronic pharyngitis, aphthous stomatitis, canker sores, epistaxis, heel bony spurs, achilles tendonitis, spontaneous perspirat, night sweat, abnormal menstruation, dysmenorrhea, and the like and also has complete function and stronger practicability.

The present disclosure is directed to modulators of cyclooxygenase (COX) enzymes and pharmaceutically acceptable salts and prodrugs thereof, the chemical synthesis thereof, and the medical use of such compounds for the treatment and / or management of the severity and duration of non-specific pain, tension-type pain, headache, migraine, lower back pain, sciatica, dental pain, muscular pain, pain associated with acute soft tissue injuries, bursitis, tendonitis, lumbago, periarthritis, tennis elbow, sprains, strains, muscular problems associated with sports injuries, muscular problems associated with accidents, period pain, primary dysmenorrhoea, acute sore throat pain, osteoarthritis, rheumatoid arthritis, cancer, any disorder requiring analgesic response, any disorder requiring anti-inflammatory response, any disorder requiring antipyretic response, any conditions mediated by cyclooxygenase, cystic fibrosis, dementia, Alzheimer's disease, and / or conditions mediated by levels of β-amyloid are described.

The present invention is related to a bilayer pharmaceutical composition comprising naproxen or a pharmaceutically acceptable salt thereof. The present invention is particularly related to a bilayer pharmaceutical composition comprising an immediate release component and a controlled release component of naproxen or a pharmaceutically acceptable salt thereof and the process for preparation thereof. Moreover, the present invention is related to the treatment of rheumatoid arthritis, oesteoarthritis, ankylosing spondylitis, pain, primary dysmenorrhoea, acute tendinitis, bursitis and acute gout.

The present invention relates to 8-Hydroxyquinoline Compounds; compositions comprising an 8-Hydroxyquinoline Compound; and methods for treating or preventing a metalloproteinase-related disorder, such as, an arthritic disorder, osteoarthritis, malignant neoplasm, rheumatoid arthritis, asthma, chronic obstructive pulmonary disease, atherosclerosis, age-related macular degeneration, myocardial infarction, a corneal ulceration, an ocular surface disease, hepatitis, an aortic aneurysm, tendonitis, a central nervous system disorder, abnormal wound healing, angiogenesis, restenosis, cirrhosis, multiple sclerosis, glomerulonephritis, graft versus host disease, diabetes, an inflammatory bowel disease, shock, invertebral disc degeneration, stroke, osteopenia or a periodontal disease or comprising administering an effective dose of an 8-Hydroxyquinoline Compound to a mammal in need thereof.

An orthopedic treatment device and method to prevent impingement of a patient's supraspinatus tendon between the head of the humerus and the coracoacromial arch in the patient's shoulder, while the patient is sleeping, or otherwise in a supine or prone position. The invention inhibits abduction of the arm. This limitation of the arm away from the body prevents the stated impingement of the supraspinatus tendon. The device is designed for treatment of rotator cuff tendonitis. This impingement is also prevented by direct traction exerted on the arm in a downward direction by the invention. The device consists of a first sleeve removably fixed around the patient's thigh and a second sleeve removably fixed around the patient's wrist, both proximate the shoulder treated. The sleeves are connected by a resilient strap which exerts traction on the arm.

Hip brace for motion control and support of the hip joint, and / or to the surrounding sacroiliac joint and / or lumbo-sacral joints concomitantly, built of configured elasticized neoprene with tensile strength, and with closures built of Velcro whose combined forces impart dynamic action and protection from hip dislocation and subluxation; range of motion control, joint protection and support, pain management, proprioceptive cueing, alignment support, resistive and assistive exercise options for people with disorders of the hip joint and as well for those with concomitant sacroiliac and lumbo-sacral instability. Medical conditions addressed include but not limited to hip pain, status post surgical hip, hip dislocation / subluxation, arthritis, sprains, strains, bursitis, tendonitis, joint hypermobility, ligamentous tears and sacroiliac and / or lumbo-sacral pain and instability, radiculitis as well as for athletes in need of hip joint and / or the sacroiliac, lumbo-sacral joint protection and support on and off the field and for everyday activities of daily living (ADL) and exercise.

The present invention relates to 8-Hydroxyquinoline Compounds; compositions comprising an 8-Hydroxyquinoline Compound; and methods for treating or preventing a metalloproteinase-related disorder, such as, an arthritic disorder, osteoarthritis, malignant neoplasm, rheumatoid arthritis, asthma, chronic obstructive pulmonary disease, atherosclerosis, age-related macular degeneration, myocardial infarction, a corneal ulceration, an ocular surface disease, hepatitis, an aortic aneurysm, tendonitis, a central nervous system disorder, abnormal wound healing, angiogenesis, restenosis, cirrhosis, multiple sclerosis, glomerulonephritis, graft versus host disease, diabetes, an inflammatory bowel disease, shock, invertebral disc degeneration, stroke, osteopenia or a periodontal disease or comprising administering an effective dose of an 8-Hydroxyquinoline Compound to a mammal in need thereof.

A low cost foldable orthosis for the treatment of foot and ankle conditions including plantar facitis and tendonitis, the orthosis is a foldable molded portion manufactured in a variety of incremental sizes, having a generally U-shaped cross-sectional configuration and a flat foot bed, interconnected by a hinge. This device includes a variety of spacers which enable the angle of covered by a soft fabric covering, and using a removable and interchangeable foot bed wedge insert permitting the angle of dorsiflexion, plantar flexion, inversion and eversion to be varied.

Provided is an ankle supporter capable of returning the wearer's ankle to a normal position by moving the connective tissue and muscles below the skin following sprain or Achilles tendonitis. The ankle supporter includes a first elastic panel knitted in a belt-like shape on the medial side of the wearer's foot extending from the sole to an area corresponding to the Achilles tendon and having a stretch resistance greater than that of the base fabric and a second elastic panel knitted in a belt-like shape on the medial side of the wearer's foot extending from the heel to the base of the foot top of the wearer to intersect the first elastic panel below the center of the medial ankle and having a stretch resistance greater than that of the base fabric.

A method treating the symptoms of tendonitis, arthritis, capsulities, lymphedema and ganglion cysts in the arm of a user which involves the steps of placing a pressure imparting device around selected portions of the user's arm and applying controlled pressure to the discrete areas of the skin directly overlying the selected portions. The pressure imparting device includes two discrete compression plates that are placed around selected portions of the user's arm and are drawn toward one another to apply bipolar transaxial compression of equal magnitude simultaneously to discrete areas of the skin directly overlying the selected portions.

The present invention generally relates to transdermal drug delivery systems. More particularly, the present invention provides compositions and transdermal drug delivery systems for the treatment and / or relief of symptoms associated with carpal tunnel syndrome or tendonitis.

Analgesic formulations to be applied topically that are reported to relieve moderate to severe pain due to tendonitis, fibromyalgia, shingles, insect bites and bee stings, ACL, arthritis, and sinus headaches. In many cases, test subjects report immediate pain relief with a single application and complete pain elimination with only a few applications. The formulations are in a coconut oil base which is skin friendly. The primary active ingredient is wrightia tinctoria, which when combined with other ingredients, causes the formulation to exhibit a synergistic effect on pain relief unexpected from using the ingredients alone or in combination.

This invention provides compositions and methods for preventing inflammatory diseases of the joints, including rheumatoid and osteoarthritis, tendonitis, bursitis, inflammation of the ligament, synovitis, gout, and systemic lupus erythematosus, wherein the methods include injecting into the inflamed joint a therapeutic anti-inflammatory composition comprising a bacterial or viral IL-10 expression construct, wherein the IL-10 expression construct comprises a bacterial or viral backbone and a nucleic acid sequence encoding interleukin-10.

The present invention relates to novel urea and thiourea compounds, compositions comprising urea or thiourea compounds, and methods useful for treating and preventing aging, Alzheimer's Disease, cancer, cardiovascular disease, diabetic nephropathy, diabetic retinopathy, a disorder of glucose metabolism, dyslipidemia, dyslipoproteinemia, enhancing bile production, enhancing reverse lipid transport, hypertension, impotence, inflammation, insulin resistance, lipid elimination in bile, modulating C reactive protein, obesity, oxysterol elimination in bile, pancreatitis, Parkinson's disease, a peroxisome proliferator activated receptor-associated disorder, phospholipid elimination in bile, renal disease, septicemia, metabolic syndrome disorders (e.g., Syndrome X), a thrombotic disorder, gastrointestinal disease, irritable bowel syndrome (IBS), inflammatory bowel disease (e.g., Crohn's Disease, ulcerative colitis), arthritis (e.g., rheumatoid arthritis, osteoarthritis), autoimmune disease (e.g., systemic lupus erythematosus), scleroderma, ankylosing spondylitis, gout and pseudogout, muscle pain: polymyositis / polymyalgia rheumatica / fibrositis; infection and arthritis, juvenile rheumatoid arthritis, tendonitis, bursitis and other soft tissue rheumatism. In certain embodiments, the compounds, compositions, and methods of the invention are useful in combination therapy with other therapeutics, such as hypocholesterolemic and hypoglycemic agents.

The present invention teaches an improved method of controlling a cursor on a computer screen, without using the hand, by strapping the mouse around the patella section of the leg with a patella strap and utilizing leg muscle movement, while sitting down, to control the direction of the cursor. After manipulating the cursor by using body movement and keeping both hands on the keyboard, the programmable function keys or another hands free or appendage attached push button, motion, or voice device are used to execute a command. By eliminating the need of hand movement to move the cursor, the user is helped to prevent the development of carpal tunnel, DeQuervains tendonitis, debilitating muscle cramps, fatigue and other repeated motion related conditions.

The invention provides a method for administering streptolysin O for treatment of various conditions including connective tissue disorders, reproductive fibroses and conditions mediated by the CD44 receptor. The invention also provides methods for protecting nerve cells from the effects of neurotoxic agents by the administration of streptolysin O.

The present disclosure is directed to modulators of cyclooxygenase (COX) enzymes and pharmaceutically acceptable salts and prodrugs thereof, the chemical synthesis thereof, and the medical use of such compounds for the treatment and / or management of the severity and duration of non-specific pain, tension-type pain, headache, migraine, lower back pain, sciatica, dental pain, muscular pain, pain associated with acute soft tissue injuries, bursitis, tendonitis, lumbago, periarthritis, tennis elbow, sprains, strains, muscular problems associated with sports injuries, muscular problems associated with accidents, period pain, primary dysmenorrhoea, acute sore throat pain, osteoarthritis, rheumatoid arthritis, cancer, any disorder requiring analgesic response, any disorder requiring anti- inflammatory response, any disorder requiring antipyretic response, any conditions mediated by cyclooxygenase, cystic fibrosis, dementia, Alzheimer's disease, and / or conditions mediated by levels of beta-amyloid are described.

The invention discloses an external power used for dredging collaterals and strengthening bones, which is prepared from traditional Chinese medical materials according to the following weight percentages: 1 percent to 5 percent of unprepared nux vomica, 10 percent to 40 percent of unprepared white mustard seeds, 5 percent to 15 percent of unprepared radix aconite, 5 percent to 15 percent of unprepared radix aconiti agrestis, 2 percent to 15 percent of herba asari, 3 percent to 11 percent of rhizoma arisaematis, 8 percent to 13 percent of radix clematidis, 1 percent to 4 percent of camphor, 1.8 percent to 3.1 percent of borneol, 0.6 percent to 0.9 percent of cantharis, 0.12 percent to 7 percent of angelica root, 0.01 percent to 0.04 percent of musk, 0.1 percent to 3.2 percent of unprepared frankincense and 1 percent to 3.2 percent of unprepared myrrh. The powder is mixed with boiled water to form a paste and taken when not hot. The power is mainly used for treating rheumatoid arthritis, atrophic arthritis, protrusion of intervertebral disc, sciatica, hyperostosis in parts of human body, scapulohumeral peri arthritis, tendonitis numb and other diseases, and is testified by the clinical applications to have quick effect and good curative effect.

This invention provides for using a locally delivered low dose of a corticosteroid to treat pain caused by any inflammatory disease including sciatica, herniated disc, stenosis, mylopathy, low back pain, facet pain, osteoarthritis, rheumatoid arthritis, osteolysis, tendonitis, carpal tunnel syndrome, or tarsal tunnel syndrome. More specifically, a locally delivered low dose of a corticosteroid can be released into the epidural space, perineural space, or the foramenal space at or near the site of a patient's pain by a drug pump or a biodegradable drug depot.

The invention discloses a traditional Chinese medicine fumigation lotion for treating achilles tendonitis and a preparation method thereof, and belongs to the field of traditional Chinese medicines. The active components of the medicine provided by the invention comprise the following raw materials: radix et folium psychotriae serpentis, radix et caulis ventilaginis leiocarpae, radix uncariae rhynchophyllae, radix salviae miltiorrhizae, elatostema stewardii merr, caulis kadsurae, herba goodyerae, rhizoma polygoni cuspidati, herba ainsliaea albo-tomentosae, herba tetrastigmatis obtecti, cortex acanthopanacis, radix glycyrrhizae, radix seu caulis kadsurae heteroclitae, cortex schefflerae octophyllae, radix cynoglossi amabilis, rhizoma ligustici chuanxiong, fructus foeniculi, dioscorea tenuipes, daphne koreana nakai, cinnamomum tamala, wikstroemia canescens, rhizoma et radix smilacis nipponicae, radix et folium murrayae and borneolum syntheticum. The traditional Chinese medicine fumigation lotion selects medicinal materials conforming to the principles of monarch, minister, assistant and guide, is applied according to cause of disease, has effects of dispelling wind and eliminating dampness, warming the meridians and dredging blood vessel, promoting blood circulation to remove blood stasis, promoting qi to activate blood circulation, reducing swelling and resolving mass, relaxing tendons and activating collaterals, strengthening the muscles and bones, and promoting circulation of qi to relieve pain, can effectively relieve pain, promotes blood circulation, accelerate tissue repair, has good absorption effect, obvious treatment effect, no toxic and side effects and no adverse clinical reactions, and is clinically proven to have high cure rate for achilles tendonitis.

This document provides methods and materials related to treating rotator cuff conditions (e.g., rotator cuff tendonitis or rotator cuff injuries such as partial rotator cuff tears). For example, methods and materials for using BMP-5 polypeptides to treat rotator cuff conditions as well as methods and materials for using inhibitors of SIRT6, SIRT7, and / or HDAC10 polypeptide expression or activity to treat rotator cuff conditions are provided.

Effective treatments of pain and / or inflammation from tendonitis, carpal tunnel syndrome, tarsal tunnel syndrome, osteoarthritis, bursitis and / or an oral-facial disease are provided. Through the administration of an effective amount of at least one alpha adrenergic agonist at or near a target site, one can reduce, prevent or treat pain and / or inflammation from tendonitis, carpal tunnel syndrome, tarsal tunnel syndrome, osteoarthritis, bursitis and / or an oral-facial disease.

A method of treating said musculoskeletal and connective tissue inflammations including osteoarthritis and associated articular and periarticular inflammations, and non-articular Rheumatism including capsulitis, tendonitis, fibrositis, and perarticular inflammations is disclosed. The method includes administering to a patient of a therapeutically effective amount of a composition comprising 13-cis-retinoic acid. Preferably, the treatment method includes administering to a patient of an initial dosage of a composition comprising 13-cis-retinoic acid for an initial treatment period, and thereafter administering a maintenance dosage of the composition.