The invention provides a formula for a bone fracture cream and a preparation method of the bone fracture cream, and relates to the field of traditional Chinese medicine. The bone fracture cream is prepared from the following raw materials: myrrh, kudzuvine root, peach kernels, ground beeltle, Chinese herbaceous peony, centipede, niu teng, mulberry twig, garden balsam stem, common clubmoss herb, pawpaw, notopterygium root, achyranthes, pinellia ternate, radix aconiti, hippocampus, frankincense, cinnamomum cassia, safflower carthamus, radix clematidis, cassia twig, pangolin, corydalis tuber, salvia miltiorrhiza water snake, Chinese alangium, rhizome zingiberis, garter snake, radix angelicae pubescentis, leaf artemisia, arisaema heterophyllum blume, pseudo-ginseng and radix saphshnikoviae. After the technical scheme of the formula for the bone fracture cream is adopted, the formula for the bone fracture cream has the beneficial effects that the bone fracture cream can treat diseases of toothache, cervical spondylosis, scapulohumeral periarthritis, hyperplasia of mammary glands, lumbar pain, lumbar spinal stenosis, lumbar muscle degeneration, enteritis, ischiadic nerve, dysmenorrhea, knee pain, rheumatism, arthritis, arthrocele, arthromeningitis, bursitis, achilles tendinitis, heel pain, traumatic injury, hyperplasia, sprain and postpartum style, wind driving and cold dissipating are achieved, tendons and collaterals activating are achieved, the treating effect is improved, and the treating range is enlarged.