110 results about "Myocardial oxygen consumption" patented technology

The invention discloses an extractive of Taxus chinensis var.mairei leaves and a preparation method. The extractive is a straw yellow powder. The powder contains sciadopitysin the weight content of which is 65-70 percent; the sciadopitysin contains the following five components: 3-O-rutin-quercetol, 3-O-rutin-campherol, 3-O-rutin-myricetin, 7-O-glucose-campherol and 7-O-glucose-quercetol, and the total weight content of the five components in the sciadopitysin is 40-60 percent. The extractive is prepared by the preparation method comprising the steps of baking, crushing and screening, immersing into an alcohol dissolvant, ultrasonically extracting while stirring, decompressing and concentrating an extracting solution to remove alcohol, extracting with chloroform and degreasing, water phase concentrating and drying by taking fresh Taxus chinensis var.mairei leaves as raw materials. The extractive of Taxus chinensis var.mairei leaves has the functions of improving heat microcirculation, resisting arrhythmia, lowering myocardial oxygen consumption and the like and having the therapeutic and health-care function on diseases of cardiovascular system; and the preparation method has low energy consumption, short extracting time, few impurities and higher extraction efficiency.

The present invention provides a helical soft capsule. Every capsule contains 5-200mg of helical, the rest is solvent matrix, the described solvent matrix is one of PEG 300-1000, propylene alcohol, soybean oil and peanut oil or their composition. According to the requirements the medicinal color matter and flavor agent can be added into its liquid medicine. Said invented soft capsule has the sedation, can obviously reduce coriamyrtin convulsion incidence rate, prolong its generative latent period, reduce frequency of attack and shorten the time and process of attack, and has the actions of stopping pain and resisting inflammation, and has a certain action of relieving vasoconstriction and raising oxygen consumption of heart muscle, and its biological utilization rate can be raised by 10-59%.

The invention discloses a pulsation type double-haematodocha heart auxiliary circulation device. Two hydraulic chambers are arranged in a blood pump shell, a first haematodocha is connected with a second haematodocha through a one-way valve in the center of a baffle at the middle part of the blood pump shell, a first cavity is arranged between the first haematodocha and the blood pump shell, a hydraulic nozzle is arranged outside the first cavity and is communicated with a first pressure cavity through a pipeline, a second cavity is arranged between the second haematodocha and the blood pump shell, a hydraulic nozzle is arranged outside the second cavity and is communicated with a second pressure cavity through a pipeline, a piston is arranged between the first pressure cavity and the second pressure cavity and is connected with a silk pole mechanism installed on a servo motor through a connecting rod, and an embedded computer is respectively connected with a display and an operation keyboard. The invention has the advantages of lightening the heart load, lowering the myocardial oxygen consumption, enhancing the blood pressure in distole, promoting the cardiac pumping function, providing restoring environment to myocardial cells, stable work, reliable running, simple device and convenient operation.

Provided are a somatic data-measuring apparatus that can easily and accurately measure the optimal exercise intensity for the subject being measured, and a somatic data measurement method. The somatic data-measuring apparatus is provided with a heart sound-acquiring means that detects the subject's heart sounds and outputs same as heart sound data, a first heart sound-extracting means that detects the first heart sound on the basis of the heart sound data, a first heart sound amplitude-measuring means that measures the amplitude from the detected first heart sound and outputs same as first heart sound amplitude data, a heart rate-counting means that measures the subject's heart rate and outputs same as heart rate data, and an exercise intensity-computing means that computes the double product of the heart rate data and the first heart sound amplitude data as double product data and detects, as the optimal exercise intensity, the exercise intensity at which the approximation line, which approximates said double product data distribution, bends. Since the double product, which represents myocardial oxygen consumption, is effective as an index that accurately reflects the state of cardiac workload, it is possible to measure accurately the degree of workload on the heart.

The invention relates to a method for extracting Yulang block to obtain Yulang water extractive, alcohol extractive, polysaccharide and chromocor. Researches have proved that the Yulang water extractive, alcohol extractive, polysaccharide and chromocor can stably reduce hypertension, restrain heart muscle retraction, reduce heart muscle oxygen consumption, improve coronary flux and reduce myocardial ischemia refill hurt, while it can release breath, release the asthma caused by acetylcholine simulation, and resist the retraction of acetylcholine or ergamine on bronchi. And the Yulang water extractive and polysaccharide can resist senile dementia and hepatitis or the like. The invention supplies a novel Chinese drug for treating hypertension, coronary disease, or the like, without side effect.

Disclosed is a pulmonary artery catheter (“PAC”) that is used in determining myocardial oxygen consumption. Myocardial oxygen consumption is of critical importance because decreased myocardial energy utilization during acute illness may lead to tissue hypoperfusion, multiple organ failure, and eventually death. The inventor has discovered that myocardial oxygen consumption is a function of the difference in oxygen levels in atrial and mixed venous blood. The invention has further discovered that differences in lactate, glucose or any other measurable blood concentration metabolite in atrial or superior vena cava and mixed venous blood can also be used in determining myocardial oxygen consumption.

The present invention relates to a cattail pollen extract, its preparation method and its application. Its preparation method includes the following steps: using aqueous ethyl alcohol to make thermalextraction of typha poller, and adopting macroporous resin adsorption chromatographic process to obtain the invented typha pollen extract whose total flavone content is up to 50%. The animal tests show that it can obviously reduce extent of myocardial ischemia after ligation of canine coronary artery, can reduce the range of myocardial ischemia, can obviously reduce infarct range and can obviously reduce myocardial oxygen consumption, etc. so that it can be used for preparing medicine or food for preventing and curing angio cardiopathy due to myocardial ischemia.

The present invention provides a therapy instrument for myocardial ischemia, which is combined with power circuit, generation circuit of modulation wave, shaping circuit of modulation wave, modulation circuit, constant current source circuit, stimulating electrode, CPLD carrier generation circuit, carrier shaping circuit, output intensity control circuit and MCU. The therapy instrument has characters of non-invasive, non-pain sense electrical stimulation, overcoming body adaptability etc., and can treat patient with comfortable sense. The therapy instrument can assistant treat myocardial ischemia by skin spinal cord and fastigial nucleus electrical stimulation. The therapy instrument modulates the random signal of low-frequency slow change rhythm on the MF carrier signal with special spectrum structure by method of pulse amplitude modulation, and loads LF current to human skin spinal cord and fastigial nucleus with forms of current by surface electrode. The therapy instrument can treat myocardial ischemia by improving coronary blood flow, reducing myocardial oxygen consumption, controlling pain and protecting neurogenic neuroprotection.

The present invention relates to a method to determine a cardiac characteristic determined at a proximal end and a distal end of a pulmonary artery catheter. The present invention also relates to a method of treating a patient based on a determination of a determined difference between a cardiac characteristic a proximal end and a distal end of a pulmonary artery catheter.

The invention relates to Sedum aizoon L. tea, which is prepared by using the following raw materials in percentage by weight: 70 to 85 percent of Sedum aizoon L. leaves, 11 to 30 percent of aloe leaves, 3 to 15 percent of ginseng leaves and 3 to 15 percent of folium cortex eucommiae, optimally 76 percent of Sedum aizoon L. leaves, 18 percent of aloe leaves, 3 percent of ginseng leaves and 3 percent of folium cortex eucommiae. Sitosterol in the Sedum aizoon L. tea can prevent the cholesterol absorption of human bodies, reduce blood fat and prevent angiosclerosis; flavones in the Sedum aizoon L. tea can expand blood vessels, promote blood circulation and reduce myocardial oxygen consumption; and oleanolic acid in the Sedum aizoon L. tea can protect liver tissues and prevent liver fibrosis. The Sedum aizoon L. tea can be drunk for a long time for strengthening body, preventing arteriosclerosis and heart diseases, protecting the liver and delaying aging.

A Chinese medicine for treating ischemic cardiovascular and cerebrovascular diseases is prepared from 3 Chinese-medicinal materials ginseng, red sage root and corydalis tuber through extracting, separating by adsorptive resin, eluting and concentrating. Its advantages are high curative effect and low cost.

The invention provides medicine for treating cardiovascular and cerebrovascular diseases. The medicine is glycoprotein, mixture of polysaccharide and protein, polypeptide or protein. The medicine has the advantages that the triglyceride and total cholesterol contents of rats can be lowered effectively; the anoxia survival time of mice can be prolonged to reach 70-85 minutes; the microcirculation can be improved, the coronary artery can be expanded, the myocardial blood supply can be improved, the blood flow of the brain and the coronary artery can be increased, the heart rate can be reduced, and the myocardial oxygen consumption index can be lowered to improve myocardial blood metabolism, resist thromboxane, increase high-density lipoprotein, resist vasospasm and reduce platelet aggregation, and the total cholesterol and triglyceride of the blood can be lowered; the medicine is safe, efficient and free of side effect.

The invention discloses novel sea buckthorn tea and a making method thereof and belongs to the field of tea processing. The novel sea buckthorn tea is sea buckthorn black tea made by subjecting sea buckthorn leaf to black tea making process; the novel sea buckthorn tea may be made into sea buckthorn Fuzhuan tea by subjecting sea buckthorn leaf to Fuzhuan tea making process among black tea making processes, wherein certain raw black tea may be added during making of the sea buckthorn Fuzhuan tea. According to the novel sea buckthorn tea and the making method thereof provided herein, sea buckthorn leaf is used as a raw material effectively combined with the black tea making process, rich nutrients in the sea buckthorn leaf are retained, sea buckthorn leaf fermentation and moldy spot appearing are achieved, and the produced sea buckthorn black tea is imparted the effects such as increasing coronary artery blood flow, reducing cardiac oxygen consumption, suppressing platelet aggregation, lowering blood pressure, lowering blood lipid, and lowering blood glucose; the produced sea buckthorn Fuzhuan tea is rich in Eurotium cristatum and has the effects such as resisting tumors, adjusting immunity, delaying senility, clearing heat and toxicity, and invigorating stomach to improve appetite.

The invention discloses a nifedipine medicine composition and a preparation method thereof. The nifedipine medicine composition contains nifedipine, hydroxymethyl propyl cellulose and microcrystalline cellulose. The hydroxymethyl propyl cellulose is used as slow-releasing framework material; the weight ratio of the nifedipine and the hydroxymethyl propyl cellulose is 2:1-1:1; and the weight ratio of the nifedipine and the microcrystalline cellulose is 1:4-1:3; and lactose, starch, calcium hydrophosphate and glucose can be also added. The method for preparing the nifedipine medicine composition comprises the following steps of: (1) crushing and screening; (2) drying; and (3) tabletting. According to the invention, the dissolution rate of the nifedipine in the water can be increased, the coronary arteries in the normal blood supply area and the ischemic area are relaxed while the absorption rate of the nifedipine in the body is increased so that coronarospasm and is released and prevented and myocardial contraction is inhibited; myocardial oxygen consumption is reduced; the peripheral resistance is released; after load of heart is reduced; sinus node function and atrioventricular conduction of the isolated heart are slowed down; and the nifedipine medicine composition is applicable to variant angina pectoris, unstable angina pectoris and chronic stable angina pectoris.

The invention discloses a method for preparing composite enzyme of kudzu vine leaves and folium mori. The method comprises the following steps of: shredding kudzu vine leaves and folium mori, squeezing, collecting a leaf liquid, pouring the squeezed kudzu vine leaves, the folium mori and the leaf liquid into a fermentation container, adding a sodium hydrogen phosphate-citrate buffer solution which is cooled in advance, adding composite enzyme and ferrous carbonate, and performing enzyme method low-temperature extraction; and preparing primary fermentation broth from the extraction filtrate, inoculating the primary fermentation broth into lactobacillus plantarum so as to obtain secondary fermentation broth, and performing solid-liquid separation on the secondary fermentation broth, thereby obtaining the composite enzyme. Due to enzyme method low-temperature extraction, nutrient elements in kudzu vine leaves and folium mori can be sufficiently extracted, and thus the effects and eating security of the product can be greatly improved; the method disclosed by the invention is simple in process, effective components of kudzu vine leaves and folium mori can be sufficiently maintained, the quality is stable, multiple effects of reducing blood vessel resistance, improving heart and brain blood circulation, reducing myocardial oxygen consumption and the like can be achieved, and a nutrient healthcare function can be achieved.

The invention belongs to the traditional Chinese medicine field, and relates to corynoxeine and an application of an isomer of the corynoxeine in preparing medicines. In the invention, the results of animal experiments prove that the corynoxeine and the isomer thereof have the effects of expanding vessels and lowering blood pressure, and can be used for preparing the medicines for expanding the vessels and lowering the blood pressure; the corynoxeine and isocorynoxeine have the effects of expanding the vessels, lowering heart afterload, lightening heart burden and decreasing myocardial oxygen consumption, and can be used for preparing anti-angina pectoris medicines; the corynoxeine has the effects of negative myodynamia, directly decreasing the myocardial oxygen consumption, and doubly lowering the myocardial oxygen consumption; the corynoxeine and the isocorynoxeine have the effects of improving the ventricular muscle excited threshold and lowering the ventricular muscle contraction frequency, can be used for treating ventricular tachycardia, and can be used as a quality identification uncaria and tagged molecules of the ffective parts of the corynoxeine and the isocorynoxeine.

The invention discloses Abelmoschus manihot flower tea. The Abelmoschus manihot flower tea is mainly produced by drying Abelmoschus manihot through a hot-air gradient drying method. The hot-air gradient drying method specifically includes: drying at 60-67 DEG C for 57-98 minutes; drying at 49-59 DEG C for 126-187 minutes; drying at 41-48 DEG C for 214-248 minutes; drying at 34-40 DEG C for 275-310 minutes. The Abelmoschus manihot flower tea has the advantage that the hot-air gradient drying can keep more biological active substances which have effects of beautifying, nourishing, regulating body immunity, lowering myocardial oxygen consumption, increasing blood quantity of coronary arteries and brain blood vessels and improving blood circulation in the Abelmoschus manihot flower tea.

The invention provides a health-care Chinese hawthorn leaf tea capable of reducing glucose and lipid. The health-care Chinese hawthorn leaf tea capable of reducing glucose and lipid comprises the following raw materials in parts by weight: 10-50 parts of Chinese hawthorn leaves, 10-20 parts of cortex magnoliae officinalis, 10-20 parts of albizia julibrissin, 10-20 parts of Chinese mosla herb, 10-20 parts of polygonatum kingianum, 10-20 parts of dried radix rehmanniae, 10-20 parts of cortex albiziae, 10-20 parts of lalang grass rhizome, 10-20 parts of poria cocos, 10-20 parts of salviae miltiorrhizae, 10-20 parts of mulberries, 10-20 parts of fortune eupatorium herb, 10-20 parts of gynostemma pentaphyllum, 10-20 parts of cortex mori radicis, 10-20 parts of cortex moutan, 10-20 parts of astragalus, 10-20 parts of coix seeds, and 10-20 parts of inula japonica. The Chinese hawthorn leaf flavonoid contained in the Chinese hawthorn leaves has a wide pharmacologic action, is especially beneficial to a cardiovascular system, has the pharmacologic actions of reducing blood pressure, reducing peripheral vascular resistance, expanding coronary artery, increasing coronary flow, reducing myocardial oxygen consumption, strengthening the heart, increasing cardiac output, resisting myocardial ischemia and platelet aggregation, improving blood rheology, removing oxygen radical, enhancing hypoxia tolerance, inducing dieresis and the like.

Myocardial hypertrophy is a pathological change of a plurality of kinds of angiocardiopathy. The main mode is the heart remodeling comprising cardiac muscle cell hypertrophy and change of the interstitial tissue component mainly. In the present invention, the nitrate medicine is used in treatment for myocardial hypertrophy caused by various reasons and excellent therapy effect is obtained. Currently the nitrate medicine is extensively applied in treatment for the coronary heart disease, the heart colicky pain and heart failure. Preload of the heart and myocardial consumption of oxygen are reduced by extension of the venous system. The drugs used in clinical field currently comprise Nitroglycerin, Amyl Nitrite, dicho nitric acid sorbite, sorbide dinitrate, 5-isosorbide dinitrate, Nitroglycerin, pentanitrol ters and itramine tosylate.

The invention discloses use of benzisoselenazolones, particularly compounds represented by the general formula (I) against ischemic myocardial injury. The compounds are characterized by selectively inhibiting Na⁺/Ca²⁺ exchange, dilating coronary artery and decreasing myocardial oxygen consumption, which possess the advantages of high activity, potent specificity and low toxicity.

A traditional Chinese medicine composition for treating coronary heart disease provided by the invention belongs to the technical field of Chinese herbal medicine. The invention aims to solve a technical problem by providing a traditional Chinese medicine for treating coronary heart disease and angina, and the medicine can effectively treat angina, and has no obvious side effects, and strong compliance to patients. A technical scheme is as below: 20-90 parts of Astragalus mongholicus, 20-30 parts of root of red-rooted salvia, 6-9 parts of Hirudo powder, 15-20 parts of Ligusticum wallichii, 9-12 parts of safflower, 12-25 parts of root of common peony, 6-9 parts of pseudo-ginseng, 20-30 parts of rhizoma acori graminei, 10-25 parts of rhizoma corydalis, 9-20 parts of long pepper, 9-15 parts of scorpion, 1-3 parts of centipede, 9-15 parts of stiff silkworm, and 20-50 parts of root of kudzu vine. The medicine provided by the invention has effects of promoting blood circulation to remove blood stasis and activating meridians to stop pain, and not only can dilate coronary artery, increase blood flow, reduce myocardial oxygen consumption, but also has effect of easing coronary spasm.

The invention belongs to the field of medicine production, in particular to a traditional Chinese medicine for reducing blood fat and a preparation method. The traditional Chinese medicine for reducing blood fat is prepared from raw materials in parts by weight as follows: 10-30 parts of natural hirudin, 8-20 parts of seafish oil preparations, 12-18 parts of danshen roots, 10-15 parts of cassia seeds, 5-10 parts of ginger powder, 3-8 parts of tartary buckwheat, 5-16 parts of hawthorn fruit and 5-10 parts of kudzuvine roots. The traditional Chinese medicine has the benefits and the technical effects as follows: the composition has better efficacy of blood fat reduction and is cheap, and the formula is simple; according to modern traditional Chinese medicine extraction, separation and preparation technologies, a reasonable preparation can be prepared from the traditional Chinese medicine composition; the traditional Chinese medicine can expand blood vessels, promote blood circulation, increase coronary perfusion flow and reduce myocardial oxygen consumption, and the treatment functions of auxiliary blood pressure reduction and blood fat reduction are comprehensively realized. The medicine composition is an elaborately-developed product in combination of traditional Chinese medicine medical skill and modern crafts in long-term practice and has a good effect on reduction of blood fat and blood pressure.

The invention relates to extract of the steroid saponin produced from the yam or the yam with the guilder leaf which has the character of containing the 80%-90% the steroid saponin in the percentage by weight. The intravenous fluid produced from the extract of the steroid saponin can not only dilate the coronary, depress the myocardial oxygen consumption, melt the thrombus, improve the myocardial ischemia and the microcirculation, amend the function of the vas endothelial cell, increase the blood stream of the brain, prevent the ischemia brain cell injury, but also drop the blood pressure, the blood fat, the blood sugar; at the same time, it has the function of resisting inflammation, ease pain, codein, preventing asthma, dispelling the myospasm, improving the immunity and resisting the allergy. So it can cure the cerebrovascular, the rheumatism and the disease of the respiratory system. The invention has the good clinic extended value because of the low dosage of the active ingredient, the efficacy, the effecting quick and the high bioavailability.

The invention discloses a method of making hawthorn dried tofu, which comprises the following raw materials in parts by weight: 1000-1200 of soybeans, 10-12 of asparagus, 10-12 of brasenia schreberi, 40-45 of hawthorn, 10-15 of salvia, 10-12 of equisetum, 10-12 of Petasites tatewakianus Kitam, 10-12 of angelica, 10-12 of cress, 10-12 of pumpkin flower, 5-8 of Cinquefoil, 20-30 of pepper, 5-8 of overlord flower, 10-12 of rose-boot, 10-12 of polygonatum, 10-12 of lentinus edodes, 10-12 of mulberry leaf , 8-10 of lily, 8-10 of cherokee rose, 5-8 of perilla leaf, 3-6 of radix bupleuri, 3 -4 of sugarcane top, and 3-6 of flasem milkvetch seed. Compared with the prior art, the invention adds a variety of wild vegetables and edible Chinese medicine ingredients. The hawthorn can promotes digestion, lower blood fat, increase coronary blood flow, reduce myocardial oxygen consumption, and has a protective effect on myocardial ischemia and oxygen deficit. Meanwhile, the invention adopts multiple grinding processes, which reduces the bean dregs and adds the dietary fiber of bean dregs to the soybean milk, improving gastrointestinal peristalsis to help defecation.