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150 results about "Heart muscle extract" patented technology

The heart has one of the highest resting oxygen extraction fractions of any organ in the body. That is, heart muscle extracts more oxygen from the blood than other organs. As such, the heart demonstrates little oxygen extraction reserve capacity with increases in metabolic demand that occur during exercise or exertion.

Method and apparatus for creation of drug delivery and/or stimulation pockets in myocardium

An apparatus and method for creating drug-filled pockets within muscle tissue, such as myocardium of the heart for increasing angiogenesis. More particularly, the apparatus has an excising assembly with a dilator tip for penetrating and advancing through the surface and body of a muscle or organ, such as the heart. Preferably, the dilator tip has a low level laser optical fiber emission to ease the passage of the excising assembly and provide thermal damage which also stimulates angiogenesis. More preferably, the dilator tip also disperses a pharmacologically active substance as the apparatus is passed through the tissue and / or creates pockets. The excising assembly is connected to a hand-held control device from which the operator pushes a switch to activate a punching mechanism within the excising assembly. The punching mechanism cuts a discrete piece of muscle tissue and traps it within the excising assembly leaving a pocket in the remaining muscle tissue. The excising assembly may also optionally release a bolus of the pharmacologically active substance into the pocket so created. Most preferably, there is a timing mechanism to measure the contraction of the heart, and the timing mechanism is synchronized with the operator's switch on the hand-held device to ensure that the punching occurs at maximum contraction of systole. A measurement guide determines how much excised tissue is trapped in the reservoir of the excising assembly. At a threshold level of filling, the surgeon will remove the excising assembly from the hand-held control device and open the punching mechanism for release of tissue. More preferably, the threshold level of filling will automatically turn off the switch to the punching mechanism to indicate to the surgeon the need to empty the excising assembly of tissue.
Owner:ECLIPSE SURGICAL TECH

Agrimony total flavone extract, preparing method and applications thereof

The invention discloses an extract of agrimony total flavonoids and an extraction and preparation method thereof; the total amount of ketosteroid compounds accounts for 25 percent to 100 percent of the total extraction matter. The invention takes agrimony as raw material and organic solvent whether containing or not containing water as extraction solvent. The extraction procedure is as following: extracting, leaching with solvent and adsorbing resin column to make purification process or using inorganic acid to regulate the PH value of concentrated solution to be no higher than 3, and then obtaining the extraction matter of agrimony after processing. Experiments prove that the extraction matter of agrimony total flavonoids has functions of antioxidation, anti-myocardial ischemia and reducing blood lipid. The extraction matter of agrimony total flavonoids can be used as food preservative and health product additive; the extraction matter of agrimony total flavonoids, carriers acceptable in pharmacy or excipient are made into various pharmaceutical dosage forms for anti-myocardial ischemia and reducing blood lipid. The invention has the advantages of simple technics and good treatment effect and can be widely used for curing or preventing coronary heart disease, hyperlipoidemia, high blood pressure or preventing cardio-cerebrovascular diseases such as atherosclerosis, etc.
Owner:CHONGQING UNIV

Dynamic monitoring system and warning method for myocardial blood oxygen supply and demand state based on heart rate and pulses

The invention relates to a dynamic monitoring system and a warning method for a myocardial blood oxygen supply and demand state based on heart rate and pulses. The dynamic monitoring system is characterized by comprising a signal acquisition unit and a display terminal, wherein the signal acquisition unit comprises an initial blood pressure setting module, a signal acquisition module and a communication module, and the signal acquisition module is used for acquiring heart rate signals via a heart rate sensor, acquiring radial artery pulse signals via a pulse pressure sensor and sending acquired signals to the display terminal; the display terminal comprises a data transmission unit, a pulse signal processing unit, an exercise intensity detecting unit and a warning unit and is used for calculating subendocardial myocardial viability by means of analyzing the radial artery pulse signals in real time and assessing the myocardial blood oxygen supply and demand state according to the current exercise intensity of a user. The invention further provides the warning method of the dynamic monitoring system. The dynamic monitoring system and the warning method have the advantages that corresponding prompts and warnings can be provided for the user according to measurement results of the subendocardial myocardial viability rate, and dynamic monitoring on myocardial blood oxygen supply and demand state of a human body can be achieved.
Owner:HEFEI INSTITUTES OF PHYSICAL SCIENCE - CHINESE ACAD OF SCI
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