Medicinal composition containing rhodiola and ginkgo leaf, and its use

A technology of extracts and compositions, applied in the field of traditional Chinese medicine preparations, can solve the problems of undiscovered Rhodiola rosea extract, etc., and achieve the effects of remarkable curative effect, safe use, and less toxic and side effects

Inactive Publication Date: 2007-06-13
杨石
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, there is no report on the compatibility of rhodiola rosea extract and ginkgo leaf extract for the treatment of stroke, coronary heart disease, angina pectoris and other cardiovascular and cerebrovascular diseases

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0073] (1) Preparation of Rhodiola rosea extract: Appropriately pulverize Rhodiola rosea raw material, select ethanol solution with 70% solvent, use 8 times, heat reflux (80°C) 3 times, each time for 2 hours, reclaim ethanol, extract Dilute the solution with an appropriate amount of purified water, let it stand, combine the extracts, filter, and concentrate appropriately, the concentrated solution is absorbed by the macroporous adsorption resin, washed with distilled water until the effluent is colorless, eluted with dilute ethanol, collected the eluent, and decompressed Recover the ethanol until there is no alcohol smell, collect the eluate, concentrate, and dry to obtain the Rhodiola rosea extract.

[0074] (2) Preparation of Ginkgo biloba extract: Ginkgo biloba raw material is broken, adding an appropriate amount of temperature is 80 ℃ concentration is 65% ethanol solution to extract 2 times, solvent consumption is 6 times, each 2 hours, reclaim solvent, Filter out medicina...

Embodiment 2

[0084] (1) Preparation of Rhodiola rosea extract: Appropriately pulverize the Rhodiola rosea raw material, use 65% ethanol solution as solvent, use 6 times the amount, heat reflux (85° C.) twice for 2 hours each time, reclaim ethanol, extract Dilute the solution with an appropriate amount of purified water, let it stand, combine the extracts, filter, and concentrate appropriately, the concentrated solution is absorbed by the macroporous adsorption resin, washed with distilled water until the effluent is colorless, eluted with dilute ethanol, collected the eluent, and decompressed Recover the ethanol until there is no alcohol smell, collect the eluate, concentrate, and dry to obtain the Rhodiola rosea extract.

[0085] (2) Preparation of Ginkgo biloba extract: Ginkgo biloba raw material is broken, adding an appropriate amount of temperature is 70 ° C concentration of 50% ethanol solution to extract 2 times, solvent consumption is 10 times, each 3 hours, reclaim solvent, Filter ...

Embodiment 3

[0095] (1) Preparation of Rhodiola rosea extract: moderately pulverize Rhodiola rosea raw materials, use 75% ethanol solution as solvent, use 10 times the amount, heat reflux (70°C) twice for 3 hours each time, reclaim ethanol, extract Dilute the solution with an appropriate amount of purified water, let it stand, combine the extracts, filter, and concentrate appropriately, the concentrated solution is absorbed by the macroporous adsorption resin, washed with distilled water until the effluent is colorless, eluted with dilute ethanol, collected the eluent, and decompressed Recover the ethanol until there is no alcohol smell, collect the eluate, concentrate, and dry to obtain the Rhodiola rosea extract.

[0096] (2) Preparation of Ginkgo biloba extract: Ginkgo biloba raw material is broken, adding an appropriate amount of temperature is 75 ℃ concentration is 60% ethanol solution to extract 2 times, solvent consumption is 10 times, each 2 hours, reclaim solvent, Filter out medic...

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PUM

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Abstract

The present invention discloses a medicine composition containing rhodiola root extract and ginkgo leaf extract for curing angiocardiopathy and cerebrovascular diseases of cerebral apoplexy, coronary heart disease and angina pectoris, etc. Said medicine composition can be made into oral tablet, capsule, granules and injection preparation.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating stroke, coronary heart disease, angina pectoris and other cardiovascular and cerebrovascular diseases, specifically a pharmaceutical composition containing rhodiola rosea and ginkgo leaf extracts and its application, belonging to the field of traditional Chinese medicine preparations. Background technique [0002] Cardiovascular and cerebrovascular diseases such as stroke, coronary heart disease and angina pectoris are currently the number one killers that endanger human health and life worldwide. According to relevant literature reports, cardiovascular and cerebrovascular diseases kill nearly 10 million people every year. More than three million people died of cardiovascular and cerebrovascular diseases. Among them, stroke, coronary heart disease and angina pectoris have the highest incidence rate, and are prone to death, disability, and recurrence. With the continuous improvement of ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/41A61K9/08A61K9/16A61K9/14A61K9/48A61P9/10
Inventor 杨石张轶伦
Owner 杨石
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