57 results about "Sedative Effects" patented technology

The present invention provides a helical soft capsule. Every capsule contains 5-200mg of helical, the rest is solvent matrix, the described solvent matrix is one of PEG 300-1000, propylene alcohol, soybean oil and peanut oil or their composition. According to the requirements the medicinal color matter and flavor agent can be added into its liquid medicine. Said invented soft capsule has the sedation, can obviously reduce coriamyrtin convulsion incidence rate, prolong its generative latent period, reduce frequency of attack and shorten the time and process of attack, and has the actions of stopping pain and resisting inflammation, and has a certain action of relieving vasoconstriction and raising oxygen consumption of heart muscle, and its biological utilization rate can be raised by 10-59%.

The present invention provides pharmaceutical compositions including a sedating antihistamine and a stimulant, and methods of use thereof. The stimulant reduces the sedation caused by the antihistamine, thereby allowing potent, but sedating, antihistamines to be used effectively.

The invention relates to a benzisoxazolyl piperidine derivative having the following general formula, a salt or a hydrate thereof,wherein R, X, Y, R′ and T are defined as in the specification. Such compounds have serotonin system modulating effects such as antagonizing effect on 5-HT2A and inhibitory effect on 5-HT reuptake. The compounds have good analgesic and sedative activities with mild toxic and side effects. The invention also relates to a composition comprising said derivative and the use thereof.

This invention relates to personalized pharmaceutical kits, packaging, compositions, and methods for treatment of a mammal, comprising at least one antihistamine for treating an allergic disease or condition in a mammal, in combination with at least one wakefulness promoting agent for preventing sedative effects during day time use, while promoting the antihistamine and sedating effect during evening use.

The invention relates to a medicine for curing the agraypnia, the effective content of the raw composition and the weight ratio as following: 5-7 shares of fruit orange magnoliavine, 13-15 shares of seed of spine date, 16-18 shares of licorice root, 23-25 shares of indian bread, 6-8 shares of indian bread and 15-17 shares of anemarrhena. The invention is characterized in that the invention has the efficiencies of tranquilizing property, relieving mental stress, replenishing qi and blood and nursing mind. The invention is applied for curing the agraypnia, the curative effect is great and the curative ratio is high. The invention has the advantages that the combination of the Chinese herbal medicine is applied; the invention has no toxic and side effects, no drug dependence; the preparation technology is simple and the drug administration is convenient.

The invention relates to a formula of a compound medicine preparation for relieving cough and preventing asthma and a preparation method thereof. The formula mainly comprises the following components in parts by weight: 5-25 parts of methoxyphenamine hydrochloride, 3-15 parts of narcotine, 10-50 parts of aminophylline, 0.1-2 parts of ketotifen fumarate, and an appropriate amount of pharmaceutically acceptable auxiliary materials. In the invention, the methoxyphenamine hydrochloride, the narcotine, the aminophylline and the ketotifen fumarate are prepared into the compound medicine preparation for the first time; and the obtained compound medicine preparation has more obvious treatment effect on diseases such as cough, asthma, bronchial asthma, asthmatic bronchitis and the like; combination of the ketotifen fumarate and the aminophylline in the formula can enhance the bronchiectasis action of the aminophylline; and the mild sedation of the ketotifen fumarate can simultaneously counteract the central nervous system stimulation action caused by the aminophylline.

The invention discloses tea with functions of calming the nerves and aiding sleep and a preparation method of the tea. The tea with functions of calming the nerves and aiding sleep is prepared by components in parts by weight as follows: 17-26 parts of lotus seeds, 7-11 parts of jujubes, 5-9 parts of millet, 4-6 parts of millet, 5-7 parts of melon seeds, 3-5 parts of walnut kernels, 4-6 parts of black sesame, 5-9 parts of lilies, 3-5 parts of smoked plum, 1-6 parts of cortex albiziae, 2-4 parts of poria cocos, 3-5 parts of radix astragali, 2-4 parts of angelica sinensis and 3-4 parts of bee honey. The tea with functions of calming the nerves and aiding sleep has the benefits as follows: the tea adopts natural herbaceous plants with functions of calming and sedation, the sleeping quality of people can be improved if the tea is taken for a long time, brain functions are adjusted, and the tea contains rich linoleic acid, amino acid, vitamin and the like, can tonify spleen, calm the nerves and adjust normal metabolism of brain cells and has no toxic and side effect on a human body.

The present invention is directed to a pharmaceutical composition and method for treatment of rhinitis and cold like symptoms, the composition includes a non-steroidal anti-inflammatory drug (NSAID), a decongestant and an antihistamine preferably in a multi-layer tablet comprising an immediate release layer and an extended release layer to optimize the delivery profile and match the duration of biological action of the multiple active agents.

The present invention provides pharmaceutical compositions comprising a flumazenil, and methods of alleviating or counteracting residual effects (e.g. drowsiness) associated with the administration of sleep / hypnotic drugs or alleviating effects of alcohol intoxication, using self administration modes of delivery.

The invention discloses nerve calming and sleeping aiding tea with dendrobium officinale, and relates to the field of nerve calming health products. The nerve calming and sleeping aiding tea comprises the following ingredients by weight: 15-25 percent of dendrobium officinale, 10-20 percent of juncus effuses, 6-16 percent of semen cassiae, 5-13 percent of radix ophiopogonis, 4-12 percent of folium mori, 6-17 percent of radix polygonati officinalis, 8-16 percent of mint, and 4-15 parts of liquorice. The formula of the nerve calming and sleeping aiding tea is reasonable in compatibility, and the nerve calming and sleeping aiding tea selects natural Chinese herbaceous plants with effects of nerve calming and sedation, can improve the sleeping quality within a short time, and not only relieves nervous mood of insomniacs well, but also has the effects of relaxing bowel and detoxifying.

A formulation for anaesthetic use is described. The formulation contains propofol, and may be used to induce and / or maintain anaesthesia or sedation in a vertebrae. The formulation additionally contains a solvent or a combination of solvents and is suitable for mixing with commonly used infusion fluids prior to injection in to a patient. The formulation may be terminally sterilised using moist heat in order to assure sterility, and contains no lipid, thereby avoiding complications associated with administration over prolonged periods of time, or to patients with disorders of fat metabolism.

The invention discloses composite essential oil with an anti-insomnia effect. The composite essential oil is prepared by mixing 1-5 parts of rose essential oil, 1-5 parts of flores aurantii essentialoil, 1-5 parts of jasmine essential oil, 1-5 parts of sweet-scented osmanthus essential oil, 1-5 parts of michelia champaca essential oil, 1-5 parts of bergamot orange essential oil, 1-5 parts of lemon essential oil, 1-5 parts of mint essential oil, 1-5 parts of holly essential oil, 1-5 parts of pelargoniums essential oil, 1-5 parts of rosemary essential oil, 1-5 parts of cedar essential oil, 1-5parts of sandalwood essential oil, 1-5 parts of linalool, 1-5 parts of acetic acid lavender ester, 1-5 parts of phenethyl alcohol, 0.1-1.5 parts of radix angelicae sinensis essential oil, 0.1-1.5 parts of benzoin, 0.1-1.5 parts of mastic, 0.1-1.5 parts of a myrrh extract, 0.1-1.5 parts of a radix notoginseng extract, 0.1-1.0 part of chuanxiong rhizome essential oil, 0.1-1.0 part of saffron essential oil, 0.1-1.0 part of rhizoma nardostachyos essential oil, 0.1-1.0 part of a rhizoma paridis extract, 5-25 parts of glycerinum, 10-50 parts of edible alcohol and 10-25 parts of purified water. The composite essential oil is unique in composition, the making technology is simple, the application method is flexible and diverse, the composite essential oil has a good nerve calming and sedative effect, the tension mood can be relieved, the mood is adjusted, the composite essential oil is applied to household aromatherapy for improving the environment smell and has a certain bacterium inhibitionand pathogen transmission prevention function, more experience can be provided for a user, and different demands are met.

The autonomic nerve regulating agent of the present invention, which, has sedative action, sleep inducing action, and stress mitigating action in individuals, regardless of individual variation in sensitivity to or preference for fragrance, contains as an active ingredient a sesquiterpene alcohol with a boiling point of 250° C. or higher, particularly cedrol.

The invention relates to a new medical application of sinomenine. The invention provides the application of sinomenine as the sole active ingredient in the preparation of a medicine for treating chronic pain accompanied by depression behavior. The present invention uses a rat model of sciatic nerve compression injury, which manifests as chronic neurogenic pain and induces depressive behavior, and confirms that sinomenine has a good analgesic effect on chronic pain, and can improve its depressive-like behavior without tolerance Adverse reactions such as acceptability and sedative effect.

Compositions, systems, and methods that can be used with a pressurized metered dose inhaler are disclosed. A pharmaceutical composition for use in a pressurized metered dose inhaler can comprise a cannabinoid composition, a co-solvent, a terpene composition, and a propellant. A pharmaceutical composition may be soluble. A system can comprise a plurality of cannabinoid compositions and / or a plurality of terpene compositions available in various combinations. One of a plurality of cannabinoid compositions and terpene composition combinations may be user-selectable in response to various factors such as a desired therapeutic benefit, sedative effect, flavor profile, or a combination of the foregoing. A method of formulating a soluble pMDI pharmaceutical composition comprising a cannabinoid composition, a co-solvent, a terpene composition, and a propellant is disclosed.

The invention discloses a pharmaceutical composition containing propofol and opioid analgesics and a use thereof. The pharmaceutical composition comprises pharmaceutically acceptable carriers, propofol as a first active component and opioid analgesics as second active components selected from fentanyl, remifentanil, sufentanil and alfentanil. The pharmaceutical composition containing propofol and opioid analgesics utilizes the combination of narcotic analgesics and a narcotic sedative, has effects of analgesia and sedation, reduces the frequency of drug administration carried out by an analgesist, makes an anesthesia induction process more convenient, obviously reduces an incidence rate and the severity of the propofol injection pain, and reduces adverse reactions of monotherapy.

The present invention relates to the field of pain management, and in particular, the management of inflammatory pain without inducing overt sedation. The present invention features compositions and treatments for inflammatory pain comprising the administration of an amount of an neurokinin (NK) antagonist in combination with a neuronal excitation inhibitor.

The present invention relates to the technical field of refreshing agents, and discloses an air refreshing agent having a refreshing effect. The air refreshing agent is characterized by comprising the following raw materials by weight: 10-20% of lemon essential oil, 10-20% of a sweet orange extract, 10-20% of eucalyptus essential oil, 1-10% of a pericarpium citri reticulatae extract, 5-15% of ethanol, and the balance of deionized water. Compared with the air refreshing agent in the prior art, the air refreshing agent of the present invention has the following advantages that: characteristics of wide raw material sources, simple formula, plant aroma odor, no requirement of addition of essence, no pollution, no toxin and no harm are provided; the air refreshing agent contains the lemon essential oil so as to provide effects of refreshing, irritability-restlessness alleviating and air purification; the air refreshing agent contains the sweet orange extract so as to provide a calming effect, and the sweet orange essential oil having the sweet orange aroma has effects of nerve calming, decompression, physical and mental pleasure maintaining, and vitality increase so as to expel emotional tension and stress and improve insomnia caused by anxiety; and the ethanol is used for disinfection sterilization.

The invention provides a traditional Chinese medicine tablet with significant pain-relieving, calming, and pain-stopping effects, and a preparation method thereof. The traditional Chinese medicine sustained-release tablet comprises Kwangsi stephania root, HPMC, acrylic resin, lactose, 95% ethanol, and magnesium stearate. The tablet provided by the invention has significant pain-relieving and pain-stopping effects, no toxicity, no addictiveness, no significant adverse reaction, and durable effect. The tablet can be applied for disease pains caused by various reasons, and for relieving pain of a patient. The adopted process method is safe, stable, and economical, and has the advantages of low loss rate and high yield. According to an extraction process, macroporous absorption resin is adopted. The material adopted during the process can be recycled and regenerated. Ethanol can be recycled and reused. Energy consumption is low, and environment pollution is prevented. During tableting, acrylic resin is adopted as a framework material. The effect of the sustained-release medicine is reliable and stable, and human body bioavailability is high.

The invention discloses a medicine for treating insomnia. The raw material composition and the weight proportion of the active ingredients of the medicine are as follows: 5-15 parts of paeonol, 5-15 parts of Atractylodes macrocephala, 10-25 parts of poria cocos, 6-6 parts of Chinese yam 14 parts, Angelica 6-14 parts, Asparagus 5-12 parts, Ophiopogon japonicus 4-10 parts, Suanzaoren 10-15 parts, Anemarrhena 12-20 parts. The present invention has very good sedative effect, and has the effects of calming the mind and calming the nerves, nourishing qi and nourishing blood, and regulating the mind and spirit. It is used for treating various insomnias, and has remarkable curative effect and high cure rate. The invention adopts Chinese herbal medicine, has neither any toxic side effect nor drug dependence, has simple preparation process, and is convenient to use.

The invention discloses a preparation method of a pharmaceutical composition with anti-anxiety effect, active pharmaceutical ingredients of the pharmaceutical composition comprise jatamans valeriana rhizome, silktree albizzia bark, spine date seed and rush, and the preparation method comprises the following steps: step 1) selecting the active pharmaceutical ingredients according to the proportion; step 2) crushing the jatamans valeriana rhizome into coarse powder, and extracting with ethanol; step 3) crushing the spine date seed and the silktree albizzia bark into the coarse powder, and extracting with water; step 4) extracting the rush with the ethanol. Simultaneously, the invention further discloses the preparation method of pharmaceutical composition capsules. A rat elevated plus-maze test, a rat vogel drinking conflict test, a spontaneous drinking test and a pain threshold test are performed on the pharmaceutical composition, and the test results show that the pharmaceutical composition has the obvious anti-anxiety effect and has no sedation or side effects.

The invention discloses a pillow for calming nerves and aiding sleep. The pillow is in a U shape and comprises a surface layer, a packing layer and sleep aiding medicine bags. The surface layer comprises an upper surface layer and a lower surface layer, the thickness of the upper surface layer is 1 / 4 to 1 / 3 that of the lower surface layer, the packing layer is arranged between the upper surface layer and the lower surface layer, and the sleep aiding medicine bags are arranged on the periphery of the upper surface layer. The pillow has the advantages that all ingredients in the sleep aiding medicine bags are natural herb plants which play soothing and calming roles, sleep quality of people can be improved, and functions of the brain are adjusted.

The invention provides a traditional Chinese medicine composition having spirit quieting and sleep helping effects, which is an internal preparation that is prepared through common pharmaceutical technologies with common auxiliary materials from the raw materials medicines comprising, by weight, 20-40 parts of wild jujube seeds, 10-20 parts of rhizoma anemarrhenae, 15-30 parts of rhizoma chuanxiong, 10-20 parts of poria cocos, and 10-20 parts of radix glycyrrhizae. In the preparation, the wild jujube seeds have the effects of quieting and calming spirit; the rhizoma anemarrhenae and the radix glycyrrhizae can relieve heat and moisturize dryness; the rhizoma chuanxiong activates blood and resolves depression so as to treat headache; and the poria cocos boosts spleen and removes dampness, tonifies heart and moving water, and quiets and nourishes the spirit, and also has the effects of diuresis and sedation. By combination of the medicines, the traditional Chinese medicine composition can regulate yin and yang and treat diseases such as insomnia, night sweating, palpitation and dizziness, and has significant therapy effects on the symptoms such as insomnia, palpitation and dizziness, is low in toxic and side effects and can significantly relieve sub-health status of human body.

The invention discloses a traditional Chinese medicine composition with a function of resolving stagnation for tranquilization. The traditional Chinese medicine composition comprises the following raw material medicines in parts by weight: 10-15 parts of cortex albiziae, 10-20 parts of tuber fleeceflower stem, 10-20 parts of jujube kernel, 6-12 parts of lucid ganoderma, 15-30 parts of Astragalus membranaceus and 10-15 parts of Angelica sinensis. Animal and clinical experiments show that the traditional Chinese medicine composition has a good effect of inducing and prolonging sleep, exerts a good sedation effect while treating insomnia, and has a good curative effect to symptoms such as depression, anxiety and irritability. The traditional Chinese medicine composition is in particular suitable for the old, children and critical patients.

The invention discloses nerve soothing and sleep helping tea. The nerve soothing and sleep helping tea is prepared from, by weight, 68%-70% of walnut diaphragma juglandis, 4%-6% of pericarpium citri reticulatae, 8%-10% of flos rosae rugosae, 1%-3% of jujube kernels, 4%-5% of fructus crataegi, 2%-3% of flowers of prinsepia uniflora Batal. and 3%-5% of cape jasmine flowers. According to the nerve soothing and sleep helping tea, the natural Chinese herb plants which have nerve soothing and calming effects are selected, therefore, the sleep quality of people can be effectively improved, and a very good treatment effect on patients suffering from insomnia and dreaminess is achieved; the brain function can be adjusted; the tea contains rich linoleic acid, amino acid, vitamins and the like, therefore, the effects of tonifying the spleen and soothing the nerves can be achieved, normal metabolism of human brain cells can be adjusted, the good mental state of people can be kept, and no toxic or side effect is generated to a human body.