57 results about "Sedative Effects" patented technology

Methods and compositions for the treatment of conditions including ocular, stress-associated, and neurodegenerative conditions in a mammal using a composition which directly or indirectly stimulates alpha 2 adrenoreceptor agonist activity with a minimum of sedation or other side effects.

The present invention provides a helical soft capsule. Every capsule contains 5-200mg of helical, the rest is solvent matrix, the described solvent matrix is one of PEG 300-1000, propylene alcohol, soybean oil and peanut oil or their composition. According to the requirements the medicinal color matter and flavor agent can be added into its liquid medicine. Said invented soft capsule has the sedation, can obviously reduce coriamyrtin convulsion incidence rate, prolong its generative latent period, reduce frequency of attack and shorten the time and process of attack, and has the actions of stopping pain and resisting inflammation, and has a certain action of relieving vasoconstriction and raising oxygen consumption of heart muscle, and its biological utilization rate can be raised by 10-59%.

The present invention provides pharmaceutical compositions including a sedating antihistamine and a stimulant, and methods of use thereof. The stimulant reduces the sedation caused by the antihistamine, thereby allowing potent, but sedating, antihistamines to be used effectively.

This invention relates to personalized pharmaceutical kits, packaging, compositions, and methods for treatment of a mammal, comprising at least one antihistamine for treating an allergic disease or condition in a mammal, in combination with at least one wakefulness promoting agent for preventing sedative effects during day time use, while promoting the antihistamine and sedating effect during evening use.

The invention relates to a formula of a compound medicine preparation for relieving cough and preventing asthma and a preparation method thereof. The formula mainly comprises the following components in parts by weight: 5-25 parts of methoxyphenamine hydrochloride, 3-15 parts of narcotine, 10-50 parts of aminophylline, 0.1-2 parts of ketotifen fumarate, and an appropriate amount of pharmaceutically acceptable auxiliary materials. In the invention, the methoxyphenamine hydrochloride, the narcotine, the aminophylline and the ketotifen fumarate are prepared into the compound medicine preparation for the first time; and the obtained compound medicine preparation has more obvious treatment effect on diseases such as cough, asthma, bronchial asthma, asthmatic bronchitis and the like; combination of the ketotifen fumarate and the aminophylline in the formula can enhance the bronchiectasis action of the aminophylline; and the mild sedation of the ketotifen fumarate can simultaneously counteract the central nervous system stimulation action caused by the aminophylline.

The present invention is directed to a pharmaceutical composition and method for treatment of rhinitis and cold like symptoms, the composition includes a non-steroidal anti-inflammatory drug (NSAID), a decongestant and an antihistamine preferably in a multi-layer tablet comprising an immediate release layer and an extended release layer to optimize the delivery profile and match the duration of biological action of the multiple active agents.

The invention discloses nerve calming and sleeping aiding tea with dendrobium officinale, and relates to the field of nerve calming health products. The nerve calming and sleeping aiding tea comprises the following ingredients by weight: 15-25 percent of dendrobium officinale, 10-20 percent of juncus effuses, 6-16 percent of semen cassiae, 5-13 percent of radix ophiopogonis, 4-12 percent of folium mori, 6-17 percent of radix polygonati officinalis, 8-16 percent of mint, and 4-15 parts of liquorice. The formula of the nerve calming and sleeping aiding tea is reasonable in compatibility, and the nerve calming and sleeping aiding tea selects natural Chinese herbaceous plants with effects of nerve calming and sedation, can improve the sleeping quality within a short time, and not only relieves nervous mood of insomniacs well, but also has the effects of relaxing bowel and detoxifying.

The autonomic nerve regulating agent of the present invention, which, has sedative action, sleep inducing action, and stress mitigating action in individuals, regardless of individual variation in sensitivity to or preference for fragrance, contains as an active ingredient a sesquiterpene alcohol with a boiling point of 250° C. or higher, particularly cedrol.

The invention discloses a pharmaceutical composition containing propofol and opioid analgesics and a use thereof. The pharmaceutical composition comprises pharmaceutically acceptable carriers, propofol as a first active component and opioid analgesics as second active components selected from fentanyl, remifentanil, sufentanil and alfentanil. The pharmaceutical composition containing propofol and opioid analgesics utilizes the combination of narcotic analgesics and a narcotic sedative, has effects of analgesia and sedation, reduces the frequency of drug administration carried out by an analgesist, makes an anesthesia induction process more convenient, obviously reduces an incidence rate and the severity of the propofol injection pain, and reduces adverse reactions of monotherapy.

The present invention relates to the field of pain management, and in particular, the management of inflammatory pain without inducing overt sedation. The present invention features compositions and treatments for inflammatory pain comprising the administration of an amount of an neurokinin (NK) antagonist in combination with a neuronal excitation inhibitor.

The invention provides a traditional Chinese medicine tablet with significant pain-relieving, calming, and pain-stopping effects, and a preparation method thereof. The traditional Chinese medicine sustained-release tablet comprises Kwangsi stephania root, HPMC, acrylic resin, lactose, 95% ethanol, and magnesium stearate. The tablet provided by the invention has significant pain-relieving and pain-stopping effects, no toxicity, no addictiveness, no significant adverse reaction, and durable effect. The tablet can be applied for disease pains caused by various reasons, and for relieving pain of a patient. The adopted process method is safe, stable, and economical, and has the advantages of low loss rate and high yield. According to an extraction process, macroporous absorption resin is adopted. The material adopted during the process can be recycled and regenerated. Ethanol can be recycled and reused. Energy consumption is low, and environment pollution is prevented. During tableting, acrylic resin is adopted as a framework material. The effect of the sustained-release medicine is reliable and stable, and human body bioavailability is high.

The invention discloses a medicine for treating insomnia. The raw material composition and the weight proportion of the active ingredients of the medicine are as follows: 5-15 parts of paeonol, 5-15 parts of Atractylodes macrocephala, 10-25 parts of poria cocos, 6-6 parts of Chinese yam 14 parts, Angelica 6-14 parts, Asparagus 5-12 parts, Ophiopogon japonicus 4-10 parts, Suanzaoren 10-15 parts, Anemarrhena 12-20 parts. The present invention has very good sedative effect, and has the effects of calming the mind and calming the nerves, nourishing qi and nourishing blood, and regulating the mind and spirit. It is used for treating various insomnias, and has remarkable curative effect and high cure rate. The invention adopts Chinese herbal medicine, has neither any toxic side effect nor drug dependence, has simple preparation process, and is convenient to use.

The invention discloses a pillow for calming nerves and aiding sleep. The pillow is in a U shape and comprises a surface layer, a packing layer and sleep aiding medicine bags. The surface layer comprises an upper surface layer and a lower surface layer, the thickness of the upper surface layer is 1/4 to 1/3 that of the lower surface layer, the packing layer is arranged between the upper surface layer and the lower surface layer, and the sleep aiding medicine bags are arranged on the periphery of the upper surface layer. The pillow has the advantages that all ingredients in the sleep aiding medicine bags are natural herb plants which play soothing and calming roles, sleep quality of people can be improved, and functions of the brain are adjusted.

The invention provides a traditional Chinese medicine composition having spirit quieting and sleep helping effects, which is an internal preparation that is prepared through common pharmaceutical technologies with common auxiliary materials from the raw materials medicines comprising, by weight, 20-40 parts of wild jujube seeds, 10-20 parts of rhizoma anemarrhenae, 15-30 parts of rhizoma chuanxiong, 10-20 parts of poria cocos, and 10-20 parts of radix glycyrrhizae. In the preparation, the wild jujube seeds have the effects of quieting and calming spirit; the rhizoma anemarrhenae and the radix glycyrrhizae can relieve heat and moisturize dryness; the rhizoma chuanxiong activates blood and resolves depression so as to treat headache; and the poria cocos boosts spleen and removes dampness, tonifies heart and moving water, and quiets and nourishes the spirit, and also has the effects of diuresis and sedation. By combination of the medicines, the traditional Chinese medicine composition can regulate yin and yang and treat diseases such as insomnia, night sweating, palpitation and dizziness, and has significant therapy effects on the symptoms such as insomnia, palpitation and dizziness, is low in toxic and side effects and can significantly relieve sub-health status of human body.