190results about How to "Has an analgesic effect" patented technology

The present invention provides a helicid powder injection and its preparation method. Every powder injection contains 25-600 mg of helicid, and the rest is medicinal auxiliary material for injection. It has good stability, can be stored for 3 years at normal temperature, its irritation is small, and its injection site has no clear change or light hyperemia, and its sedation effect is good, and its convulsion-resisting action is strong, it can obviously reduce coriamyrtin convulsion incidence rate, prolong generative latent period, reduce frequency of attack and shorten time and process of attack. The tests show that said helicid powder injection has the strong action of stopping pain and relieving inflammation.

The present invention provides a helical soft capsule. Every capsule contains 5-200mg of helical, the rest is solvent matrix, the described solvent matrix is one of PEG 300-1000, propylene alcohol, soybean oil and peanut oil or their composition. According to the requirements the medicinal color matter and flavor agent can be added into its liquid medicine. Said invented soft capsule has the sedation, can obviously reduce coriamyrtin convulsion incidence rate, prolong its generative latent period, reduce frequency of attack and shorten the time and process of attack, and has the actions of stopping pain and resisting inflammation, and has a certain action of relieving vasoconstriction and raising oxygen consumption of heart muscle, and its biological utilization rate can be raised by 10-59%.

An artificial culture method of new balm cricket Penicillium notatum and extraction and application of delivery pains compounds are disclosed. This invention involves declutching and breeding quality new balm cricket Penicillium notatum APC-20 from nature, researching production of the strain, further, defining method of extracting delivery pains compounds to be medicine. The compound is N6-(2- hydroxyethyl) adenosine. Molecular weight is 311.297. Molecular formula is C12H17N5O5. Delivery pains ratio is 99%by the method of mouse test. Principle of delivery pains is particular and cannot induce addiction.

The invention discloses a lignum naucleae leaf extract which is characterized in that the extract is obtained by using one of the following methods: (1) the lignum naucleae leaf extract is obtained by water extraction and impurity removal of traditional Chinese medicine lignum naucleae leaves; (2) the lignum naucleae leaf extract is obtained by alcohol extraction and impurity removal of the traditional Chinese medicine lignum naucleae leaves; (3) the lignum naucleae leaf extract is obtained by lipophilic organic solvent extraction and impurity removal of the traditional Chinese medicine lignum naucleae leaves, and the lipophilic organic solvent includes but not limited by n-butyl alcohol or ethyl acetate. The invention further discloses a preparation method of the lignum naucleae leaf extract, a preparation and a new purpose. The lignum naucleae leaf extract of the invention has exact effects of clearing heat and removing toxin. The extraction process of the invention is simple and reasonable, which can obtain the effective parts. The invention opens up a precedent of obtaining the lignum naucleae leaf extract from the lignum naucleae leaves to be used for the drugs for clearing heat and removing toxin, which can not only ease the shortage of raw materials, but is also conductive to the sustainable and rational development, utilization and protection of lignum naucleae resources.

The invention relates to a special animal nutrient for milk cows and a preparation method thereof. The special animal nutrient for milk cows comprises the following components in percentage by weight: 40-60% of fulvic acid, 0.2-0.5% of taraxacum total flavone and 39.5-59.5% of fenugreek pulp fermented culture. The preparation method comprises the following steps: extracting fulvic acid; preparingfenugreek pulp fermented culture; and evenly mixing 40-60% of fulvic acid, 0.2-0.5% of taraxacum total flavone and 39.5-59.5% of fenugreek pulp fermented culture. The special animal nutrient for milkcows has obvious effects of improving the gastrointestinal function, enhancing the immunity of the organism, lowering the morbidity of mastitis and increasing the milk yield, has the advantages of high safety and convenience as well as stable performance, and is easy to store.

The invention discloses acid-sensitive controlled-release anti-inflammatory gel. The gel is formed by phenylboronic acid modified hyaluronic acid and tannic acid under the neutral to slightly alkalinecondition, and tannic acid can be released under the acidic condition. Amiloride and analogues or non-steroidal anti-inflammatory drugs thereof can be added to the anti-inflammatory gel. The invention also discloses a preparation method of the acid-sensitive controlled-release anti-inflammatory gel. The method comprises two steps including preparation of phenylboronic acid modified hyaluronic acid and preparation of the acid-sensitive controlled-release anti-inflammatory gel. The invention also discloses an application of the acid-sensitive controlled-release anti-inflammatory gel in preparation of drugs for treating physiological and pathologic change related diseases caused by decrease of pH value due to gathering of inflammatory metabolites. The gel has the lubricating function of hyaluronic acid, can relieve the stress of joints and promote backflow and update of metabolism, also has the non-specific anti-inflammatory, antioxidation, anti-effusion and analgesia functions of tannicacid, can inhibit excessive inflammatory response and body hypermetabolic reaction and is a new controlled-release anti-inflammatory gel.

A Chinese medicine for treating hypertension, headache, dizziness, tinnitces, insomnia, etc is prepared from 11 Chinese-medicinal materials including gastrodia tuber, capejasmine fruit, scutellaria root, motherwort, etc. Its preparing process is also disclosed.

The Chinese medicine ointment for treating acute and chronic osteoarthropathy is prepared with Sichuan aconite root, wild aconite, cassia twig, achranthes root, dahurian angelica root and other over 30 kinds of Chinese medicinal materials and through soaking in bean oil, decoction, mixing, spreading to cotton cloth, folding to seal and other steps. It has the functions of warming meridian, expelling cold and wetness, promoting blood circulation to disperse blood clots, dredging merdian, etc. and has obvious curative effect on acute and chronic rheumatoid arthritis.

The invention discloses a plant compound extract-containing skin care composition, aiming at providing a plant compound extract-containing skin care composition which has effects of improving the skin barrier function, repairing blood capillaries, improving blood microcirculation, relieving and resisting inflammation, and effectively repairing facial couperose skin. The technical key points are as follows: the composition is prepared from the following components by weight percent: 5-15% of a plant compound extract, 1-5% of a pelvetia canaliculata extract, 0.5-5% of palmaria palmata extract, 30-50% of propylene glycol and the balance of water, wherein the plant compound extract is prepared from the following raw materials in parts by weight: 5-15% of radix hamamelis, 5-15 parts of flores arnicae, 5-15 parts of horse boat chestnut and 5-10 parts of vaccinium myrtillus. The plant compound extract-containing skin care composition belongs to the field of cosmetics.

The invention discloses an external washing lotion for treating gynecological inflammation and belongs to the technical field of medicines. The external washing lotion for treating gynecological inflammation is prepared from lightyellow sophora root, common cnidium fruit, phellodendron, dandelion and borneol, has effects of clearing away heat and drying dampness, and killing parasites to relieve itching, and can be mainly used for treating colpitis. The external washing lotion is used clinically for many years and has obvious curative effects.

The inventin is named a method for extraction of N6-(2-hydroxyethyl) adenosine from paecilomyces cicadae culture. The invention consists of seperating and breeding new bacterial strain APC-20 of paecilomyces cicadae which is of strong livabitity, high yield of metabolically active compound and good quality from the nature; presenting a method for industrialized solid culture, fluid culture or fermentation production; then eatracting analgesic compounds contained in the said fermented product with 0.36 % of extraction rate and every significant part and providing a method for preparing polytypic species of analgesic drug; the compound has 99 % of analgesic rate examined by little white mouse-twist method. The analgesic mechanism of this compound is different from the presently used opium analgesic agent, and is of no addiction and safe, so it has a broad development and application propect.

The invention discloses a method for preparing tablets for treating enteritis and its quality control method, wherein the tablets comprise creeping euphorbia 330-1120 parts, goldhair hedyotis herb 450-1530 parts, camphor root 330-1120 parts, nutgrass flatsedge rhizome 150-560 parts, maple leaves 150-560 parts and camphor 0.2-3 parts. The preparing process consists of disintegrating the raw materials, extracting with water, concentrating the water extract liquid at 80 Deg C. to a relative density of 1.05-1.35, granulating, drying and tabletting.

The invention discloses a nursing patch for bedsore, and belongs to the technical field of traditional Chinese medicines. The nursing patch is prepared from the following raw materials: radix sophorae flavescentis, raw rhubarb, golden cypress, scutellaria baicalensis, ligusticum wallichii, corydalis tuber, curcuma zedoary, raw sanguisorba officinalis, cortex lycii radicis, rehmannia, rabdosia rubescens, astragalus membranaceus, angelica sinensis, frankincense, myrrh, radix ampelopsis, radix angelicae, flowers carthami, radix angelicae pubescentis, david poplar leaves, eucalyptus leaves, pseudo-ginseng, lucid ganoderma, root of red-rooted salvia, szechwan chinaberry fruit, Chinese herbaceous peony, rose, arabian jasmine flower, liquorice, talcum powder, gypsum, zinc oxide, medicinal zinc stearate, menthol, borneol, aloe, chorion ovi, vitamin B and activated carbon. The respective medicines have synergistic effects, have the effects of clearing away heat and toxic materials, tonifying qi and dredging collaterals, nourishing blood and moistening skin, and healing sores and promoting granulation, are capable of promoting the regulating function of the organism after being taken and accelerating wound healing, and have an analgesic effect; the pain of a sufferer in the treatment process is reduced; and the nursing patch can play a role in treating both symptoms and root causes in treatment of the bedsore.

The invention relates to an application of nicotinamide adenine dinucleotide to prepare drug for treating inflammatory pain. The modern pharmacological experiment proves that after injecting nicotinamide adenine dinucleotide to an ICR mouse, the nicotinamide adenine dinucleotide has analgesic effect to the inflammatory pain induced by formalin or complete Freund's adjuvant; it indicates that the nicotinamide adenine dinucleotide can be applied to treat inflammatory pain.

The invention discloses a novel medicinal use of the active parts of abelmoschus manihot general flavones, in particular use of the active parts of abelmoschus manihot general flavones in the preparation of medicaments for treating urinary tract infection including cystitis and urethritis. Abelmoschus manihot has the effects of disinhibiting water, dissipating stasis, dispersing swelling, detoxification and relieving common symptoms of urinary tract infection, such as frequent micturition, urgent urination, odynuria and unwell micturition. The active parts of abelmoschus manihot general flavones have excellent inhibiting effects on staphylococcus aureus, staphylococcus epidermidis and other gram-positive bacteria and negative bacteria, and have anti-inflammatory and pain-relieving effects and an obvious diuretic effect. Therefore, the active parts of abelmoschus manihot general flavones have excellent effects on the treatment of urinary tract infection, particularly chronic recurrent urinary tract infection.

The present invention discloses one kind of medicine for treating osteoporosis and its preparation process. The medicine is developed based on the Chinese medicine theory of benefiting liver and kidney to strengthen bones and muscles, and is prepared with seven kinds of Chinese medicinal materials, including malaytea scurfpea fruit, epimedium, wolfberry fruit, privet fruit, drynaria rhizome, cibot rhizome and cyathula root and proper amount of supplementary material. The medicine has the functions of invigorating liver and kidney, strengthening bone and relieving pain, and possesses obvious curative effect on osteoporosis and no side effect. The medicine may be prepared into different preparation forms for different clinical requirements.

The invention discloses a novel skeleton alkaloid compound. The novel skeleton alkaloid compound has a molecular formula of C18H26N2O, is named as Oleracimine and is shown in the chemical structural formula (I). The invention provides an extraction separation method of the novel skeleton alkaloid compound. The extraction separation method orderly comprises water decoction extraction, macroporous adsorption resin extraction, ethyl acetate extraction, silica gel column chromatography, ODS medium-pressure column treatment and Sephadex LH-20 treatment. The extraction separation method realizes simple and fast extraction separation of the novel skeleton alkaloid compound with a unique skeleton. The novel skeleton alkaloid compound has the effect of easing pain and can be used for preparation of pain easing drugs. The novel skeleton alkaloid compound is shown in the formula (I).

A Ca-Al suspension for treating baby diarrhea contains syringol, calcium carbonate, magnesium trisilicate, aluminium oxide, suspending aid, and cane sugar. Its advantages are high curative effect, low toxic by-effect and low cost.

The invention discloses a medicine composition with the functions of narcotizing in an operation and alleviating pain after the operation. The medicine composition comprises tetracaine, bupivacaine, mastic, rhizoma cyperi, girald daphne bark, white peony root and menthol. The medicine composition is added with conventional auxiliary materials in pharmacy according to a conventional process to prepare a clinically acceptable medicament form. The medicine composition is a medicine for injecting and narcotizing in the operation and alleviating pain in a long acting way after the operation and is already applied to clinic successfully throughout the years. The medicine composition can enable the surgical field to be clear, can also avoid pain, sagging distention, frequent defecation and uroschesis caused by the operation, can loosen the anal canal fully and is convenient for the surgical operation.

The invention belongs to the technical field of medicine materials, and in particular relates to skin wound bio-induced active dressing, and a preparation method and application thereof. The skin wound bio-induced active dressing comprises the following components in parts by weight: 18 to 22 parts of chitosan polymer, 30 to 50 parts of sodium alginate, 5 to 9 parts of dilantin, 12 to 18 parts ofstrontium borate doped bioactive glass, 5 to 10 parts of spirulina powder, 16 to 22 parts of ethanol, 13 to 17 parts of glycerinum and 200 to 300 parts of water for injection. The skin wound bio-induced active dressing provided by the invention is scientific and reasonable in compatibility, the components are interacted, the optimal environment is provided for growth and healing of wound, and remarkable bacteriostatic, inflammation-diminishing and analgesic effects are achieved; in addition, the bioactive glass serving as a carrier not only can control the release speed of the effective components in the dressing, but also can effectively promote healing of the wound and shorten the healing time.

The invention discloses a preparation method of a chitosan oligosaccharide nanoparticle. When a conjugate formed by coupling chitosan oligosaccharide which is good in biocompatibility and biodegradable with an analgesic medicament ibuprofen is dispersed in water, hydrophobic ibuprofen is self-assembled to form a core of the nanoparticle, and hydrophilic chitosan oligosaccharide is self-assembled to form a spherical shell, so that the chitosan oligosaccharide-ibuprofen nanoparticle is formed. The ibuprofen has good hydrophobicity, and therefore, the obtained nanoparticle has a smaller average particle size and relatively uniform distribution. The hydrophobic core of the chitosan oligosaccharide-ibuprofen nanoparticle has a good affinity action on the hydrophobic medicament, and the loaded hydrophobic anti-tumor medicament can be used for improving targeting, hypotoxicity and slow release effect of the medicament. The chitosan oligosaccharide-ibuprofen nanoparticle loaded with the hydrophobic anti-tumor medicament has a good slow release effect. And meanwhile, the ibuprofen in the nanoparticle can be used for achieving an analgesic effect.

A Chinese medicine for treating rheumatism is prepared from 10 Chinese-medicinal materials including Sichuan aconite tip, clematis root, ho malomena rhizome, pinellia tuber, etc.. Its advantages are quickly high effect and no by-effect.

The invention discloses medical ray protection spray. The protection spray is prepared from active ingredients including SOD (superoxide dismutase), curcumin, sodium alginate, potassium sorbate and sorbitol, and purified water. For the ingredients adopted by the medical ray protection spray, curcumin has the efficacies of resisting bacteria, resisting inflammation and easing pain, potassium sorbate can inhibit the microbial growth, sorbitol has the moisturizing function, meanwhile, sodium alginate is large in molecular weight, the interior of the space structure of sodium alginate contains many loose micropore structures which can wrap SOD in the gel form, and moreover, sodium alginate has the capacity of forming gel, thus improving the stability of SOD (superoxide dismutase). After the protection spray is sprayed to the skin surface of a patient, sodium alginate can control SOD, so that SOD is slowly released, and therefore, the drug action of the product is prolonged and improved.

Two extracts VT-1 and VT-2 of shrub chastetree fruit for treating periodic mastodynia, menalgia and premenstrual syndrome is prepared through extracting in mixture of water and methanol or ethanol, separating by adsorptive resin to remove impurities, and eluting by the aqueous solution of alcohol with different concentrations.

The present invention is externally applied emulsion for treating dermatitis and eczema, and the emulsion is prepared with clobetasol propionate in 1 weight portions and borneol in 30-50 weight portions as the effective components and through conventional preparation process. The material for the emulsion includes also excipient of octadecanol, stearic acid, glycerol monostearate, liquid paraffin, glycerin, HR-S1 emulsifier, emulsifying silica oil and ethyl hydroxybenzoate. Animal experiments show that the emulsion of the present invention has the functions of resisting inflammation, resisting eczema, stopping itch and relieving pain, and may be used in clinical experiment.

The invention relates to application of sugar, in particular to the application of algin oligosaccharide. The invention is characterized in that the algin oligosaccharide is used as a bacteriostat of germs or epiphyte. The invention proves that the bacteriostat can effectively inhibit the growing of Gram-negative bacteria or positive bacteria by bacteriostatic experiments, and shows broad spectrum antibiotic activity; the algin oligosaccharide is proved to have an antiinflammatory action and certain abirritation by acute inflammation experiments on animals.

A slow-release Buluoweima tablet for treating cold and its complecations (headache, fever, throat pain, etc) is composed of the color-layer particles prepared from ibuprofen, pseudoephedrine hydrochloride, acrylic resin B, hydroxypropyl methylcellulose, lactose, iron oxide, and talk powder, and the white-layer particles prepared from libuprofen, acrylic resin B, hydroxypropyl methylcellulose, talc powder and alcohol. Its preparing process is also disclosed.

The invention discloses a compound terramycin injection and a preparation method thereof. The compound terramycin injection comprises, by weight, 20 parts of terramycin, 2 parts of flunixin meglumine, 30-40 parts of propylene glycol, 10-15 parts of dimethyl formamide, 3 parts of polyvinylpyrrolidone, 6-7 parts of magnesium oxide, 0.5 parts of an anti-oxidant, 6.1-6.5 parts of ethanolamine and 28 parts of injection water. The compound terramycin injection can be used for treating therapy-sensitive infectious diseases caused by gram-positive bacteria and gram-negative bacteria, rickettsia and mycoplasma and has good treatment effects. The compound terramycin injection has good stability, does not discolor after being heated or stored for a long time, does not product precipitates, solves the problem that under the acid or alkaline conditions, the existing terramycin injection discolors or precipitates after being heated or stored for a long time so that titer is reduced, and can slowly release drug active components in the human body so that long-acting effects are obtained.

A Chinese medicine for treating menalgia is prepared from 9 Chinese-medicinal materials including astragalus root, Chinese angelica root, white peony root, Chuan-xiong rhizome, etc. its preparing process is also disclosed.

The invention relates to a girald daphne bark adhesive paste. The adhesive paste is prepared from the following raw materials in parts by weight: 5-10 parts of a traditional Chinese medicine extract, 1-5 parts of an adhesive, 0.1-0.5 part of a filling agent, 0.1-0.5 part of a transdermal absorption enhancer, 5-15 parts of a moisturizing agent, 0.1-0.5 part of a crosslinking agent, 0.1-0.5 part of a crosslinking regulator, 0.1-0.5 part of a thickening agent and 15-20 parts of distilled water. Meanwhile, the invention also discloses a preparation method of the girald daphne bark adhesive paste. The girald daphne bark adhesive paste disclosed by the invention has the effects of resisting inflammation and easing pain, and can be applied to the treatment on rheumatism, rheumatoid diseases and swellings and pains caused by various reasons.