Traditional Chinese medicine sustained-release tablet with pain relieving effect, and preparation method thereof

A technology of sustained-release tablets and traditional Chinese medicine, which is applied in the directions of non-active ingredients medical preparations, medical preparations containing active ingredients, non-central pain relievers, etc. and other problems to achieve non-addictive, pain relief, and lasting effects

Inactive Publication Date: 2013-11-13
PHARMA FACTORY GUANGXI MEDICAL UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Traditional Chinese medicine sustained-release tablets have the advantages of less frequent use, convenient use, stable blood drug concentration, avoiding peak and valley phenomena, and relatively reduced adverse reactions, avoiding the disadvantages of l

Method used

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Embodiment Construction

[0014] The traditional Chinese medicine sustained-release tablet with analgesic effect of the present invention comprises 100 g of Guangxi Dirong, 30 g of HPMC, 30 g of acrylic resin, 40 g of lactose, an appropriate amount of 95% ethanol, and 3 g of magnesium stearate.

[0015] The preparation method of the Chinese medicine slow-release tablet with analgesic effect of the present invention, comprises the steps:

[0016] (1) Extract Guangxi Dirong with water and ethanol precipitation, filter the ethanol solution, treat the filtrate with macroporous adsorption resin AB-8, elute with hydrochloric acid solution, collect the final eluent, concentrate and dry to obtain a dry paste for future use.

[0017] (2) Inclusion of the dry extract powder obtained in step (1) and cyclodextrin at a ratio of 1:1: first make a water-saturated solution of cyclodextrin, then add the dry extract powder, and grind until a paste is formed Shape, dry at low temperature to obtain cyclodextrin inclusion ...

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Abstract

The invention provides a traditional Chinese medicine tablet with significant pain-relieving, calming, and pain-stopping effects, and a preparation method thereof. The traditional Chinese medicine sustained-release tablet comprises Kwangsi stephania root, HPMC, acrylic resin, lactose, 95% ethanol, and magnesium stearate. The tablet provided by the invention has significant pain-relieving and pain-stopping effects, no toxicity, no addictiveness, no significant adverse reaction, and durable effect. The tablet can be applied for disease pains caused by various reasons, and for relieving pain of a patient. The adopted process method is safe, stable, and economical, and has the advantages of low loss rate and high yield. According to an extraction process, macroporous absorption resin is adopted. The material adopted during the process can be recycled and regenerated. Ethanol can be recycled and reused. Energy consumption is low, and environment pollution is prevented. During tableting, acrylic resin is adopted as a framework material. The effect of the sustained-release medicine is reliable and stable, and human body bioavailability is high.

Description

technical field [0001] The invention relates to an analgesic and a preparation method thereof, in particular to a traditional Chinese medicine sustained-release tablet with analgesic effect and a preparation method thereof. Background technique [0002] Traditional Chinese medicine sustained-release tablets have the advantages of less frequent use, convenient use, stable blood drug concentration, avoiding peaks and valleys, and relatively reduced adverse reactions, avoiding the disadvantages of low bioavailability, inconvenient taking, and slow onset of traditional Chinese medicine. However, there are fewer varieties of traditional Chinese medicine tablets with analgesic effect in China at present, especially fewer varieties of sustained-release tablets. Contents of the invention [0003] The invention provides a traditional Chinese medicine slow-release tablet with obvious analgesic, sedative and analgesic effects and a preparation method thereof. [0004] The traditiona...

Claims

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Application Information

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IPC IPC(8): A61K36/59A61K9/22A61K47/38A61P25/04A61P29/02
Inventor 王捷龙禹韦锦斌黎渊弘刘颖新
Owner PHARMA FACTORY GUANGXI MEDICAL UNIV
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