Buluoweima slow-release tablet and its preparing method

A technology of sustained-release tablets, parts by weight, applied in the field of human medicine, to achieve the effect of relieving sinus congestion and good safety

Active Publication Date: 2006-11-29
哈尔滨格拉雷药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since there is no single drug to relieve the many coexisting symptoms, various combination preparations have been developed

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0086] Ibuproxen pseudoephedrine sustained-release tablets and preparation method thereof, the composition includes: colored layer particles and white layer particles, the weight ratio of the raw material ibuprofen in the colored layer particles is 80 grams, and the weight parts of pseudoephedrine hydrochloride The ratio is 30 grams, the weight ratio of acrylic resin No. II is 40 grams, the weight ratio of hypromellose is 10 grams, the weight ratio of lactose is 10 grams, and the weight ratio of iron oxide is 2 grams, the weight ratio of talc powder containing 1% iron oxide is 6.66 grams, and the binder in the colored layer is 80% ethanol solution containing 2% polyacrylic resin No. II and 2% hypromellose The weight ratio is 28 grams, the weight ratio of ibuprofen in the white layer particles is 120 grams, the weight ratio of acrylic resin No. II is 30 grams, and the weight ratio of hypromellose is 5. The weight ratio of talc powder is 6.66 grams, and the weight ratio of humectant...

Embodiment 2

[0093] Ibuproxen pseudoephedrine sustained-release tablets and preparation method thereof, the composition includes: colored layer particles and white layer particles, the weight ratio of the raw material ibuprofen in the colored layer particles is 80 grams, and the weight parts of pseudoephedrine hydrochloride The ratio is 30 grams, the weight ratio of acrylic resin No. II is 40 grams, the weight ratio of hypromellose is 10 grams, the weight ratio of lactose is 10 grams, and the weight ratio of iron oxide is 2.5 grams, the weight ratio of talc powder containing 1% iron oxide is 6.66 grams, and the binder in the colored layer is the weight of 80% ethanol solution containing 2% polyacrylic resin No. II and 2% hypromellose The weight ratio is 28 grams, the weight ratio of ibuprofen in the white layer particles is 120 grams, the weight ratio of acrylic resin No. II is 30 grams, and the weight ratio of hypromellose is 5. The weight ratio of talc powder is 6.66 grams, and the weight ra...

Embodiment 3

[0100] Ibuproxen pseudoephedrine sustained-release tablets and preparation method thereof, the composition includes: colored layer particles and white layer particles, the weight ratio of the raw material ibuprofen in the colored layer particles is 80 grams, and the weight parts of pseudoephedrine hydrochloride The ratio is 30 grams, the weight ratio of acrylic resin No. II is 40 grams, the weight ratio of hypromellose is 10 grams, the weight ratio of lactose is 10 grams, and the weight ratio of iron oxide is 3 grams, the weight ratio of talc powder containing 1% iron oxide is 6.66 grams, and the binder in the colored layer is 80% ethanol solution containing 2% polyacrylic resin No. II and 2% hypromellose The weight ratio is 28 grams, the weight ratio of ibuprofen in the white layer particles is 120 grams, the weight ratio of acrylic resin No. II is 30 grams, and the weight ratio of hypromellose is 5. The weight ratio of talc powder containing 1% iron oxide is 6.66 grams, and the ...

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PUM

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Abstract

A slow-release Buluoweima tablet for treating cold and its complecations (headache, fever, throat pain, etc) is composed of the color-layer particles prepared from ibuprofen, pseudoephedrine hydrochloride, acrylic resin B, hydroxypropyl methylcellulose, lactose, iron oxide, and talk powder, and the white-layer particles prepared from libuprofen, acrylic resin B, hydroxypropyl methylcellulose, talc powder and alcohol. Its preparing process is also disclosed.

Description

Technical field: [0001] The invention relates to a human medicine, which is an oral anti-inflammatory, analgesic, and antipyretic sustained-release ibuprofen and pseudoephedrine tablet, and a preparation method thereof. Background technique: [0002] A cold is a mucosal infection of the upper respiratory tract caused by many different types of viruses. Its main symptoms are often nasal congestion, sneezing, dry cough, mild sore throat and fever, and systemic symptoms such as general discomfort, headache and myalgia. Since there is no specific treatment at all, virus identification is not necessary, and only symptomatic therapy can be used to relieve many symptoms of a cold. Since there is no medicine to relieve many coexisting symptoms, various compound preparations have come out. These compound preparations use different medicinal drugs to form a compound to relieve different symptoms that exist simultaneously. If the patient has multiple symptoms, especially in the early stages...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/192A61K9/22A61P29/00A61P11/02A61P11/04A61K31/137
Inventor 张利
Owner 哈尔滨格拉雷药业有限公司
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