17 results about "Human medicine" patented technology

A tool kit for minimally invasive implantation of a tendon fixation implant in the field of arthroscopic human medicine is provided. The tendon fixation implant includes a medial anchor, a lateral anchor, and a base plate. The tool kit includes a medial anchor inserter having a medial anchor drive mandrel and a medial anchor release tube. The medial anchor release tube is designed to receive the medial anchor drive mandrel. The medial anchor drive mandrel is designed both to receive a medial anchor and to introduce the medial anchor into bone by driving it into the latter. The medial anchor drive mandrel has a locking head for locking the medial anchor drive mandrel to the medial anchor release tube. The tool kit includes a base-plate inserter having a handpiece and a base-plate inserter tube designed to receive the base plate of the tendon fixation plate.

The present invention provides novel ionizable lipids and novel lipid nanoparticles comprising messenger RNA (mRNA) useful for the delivery of nucleic acids as defined herein, related pharmaceutical compositions or vaccines for use in human medicine or veterinary medicine, in particular for the treatment and / or prevention of cancer diseases.

The present invention relates to novel compounds and their use as therapeutic agents in human medicine and veterinary medicine. The compounds of the present invention are useful in the treatment and prevention of hyperproliferative disorders, including cancer.

Blood mixing device for veterinary and human medicine, comprising a pivoting table (1) for tube storage of at least one blood collection tube (2) and a drive unit (3), characterized in that the drive unit (3) and the gear mechanism (4) are coupled such that they simultaneously generate a rotational movement of the tube storage (2) and a pivoting movement of the pivoting table (1).

The invention discloses a culture solution for improving the development rate of in-vitro cultured pig blastocysts as well as application and a use method of the culture solution, and belongs to the technical field of livestock embryo engineering. The invention discloses a culture solution for improving the development rate of in-vitro cultured pig blastocysts, which is characterized in that a PZM3 culture solution is used as a basic culture solution, and 5-25ng / mL of tumor necrosis factor superfamily cell factor TNFSF12 is added. According to the present invention, the pig embryo needs to be subjected to in-vitro culture for 4 days in the TNFSF12-free basic culture solution, and then is transferred to the TNFSF12-containing basic culture solution so as to be continuously cultured for 2 days, such that the generation efficiency of the pig blastocyst can be effectively improved, and the support is provided for the application of the pig in-vitro fertilization, the somatic cell nuclear transfer, the embryo genome selection and other embryo engineering technologies in the agricultural breeding and the human medicine;

The present invention relates to a method for addressing tumor-promoting inflammation by means of a pharmaceutical preparation. Leukocytes are separated from a buffy coat obtained from whole blood, and a portion of the leukocytes are placed in a first bag receiving differentiation factors and stored for several days under conditions that maintain cell viability before providing a fresh medium with defined composition, after which the leukocyte portion is left to rest for several more days, resulting in the production of macrophages. Another portion of the leukocytes is placed in a second bag and irradiated therein. The two bags are then mixed, and the supernatant is recovered for use as a pharmaceutical preparation. The present invention also relates to the use of the leukocytes alone or in combination with other therapies for the treatment of cancer in human and veterinary medicine.

The present application provides a kind of detection method of bacterial endotoxin in PHA gel filling agent.The filling agent of the present application comprises PHA microspheres, gel carrier sodium carboxymethyl cellulose, osmotic pressure regulator, pH regulator and water for injection, the present application systematically studies the influence of gel carrier and osmotic pressure regulator on the performance of composition shear viscosity and osmotic pressure, and scientifically selects the excellent and stable gel prescription.The present application accidentally finds that the combination of water and a small amount of dichloromethane can realize the sufficient release of endotoxin, and accurately detect its content.The method of the present application can effectively ensure the safety of human medicine, and has important industrial value.

A kit for minimally invasive implantation of a tendon fixation implant in the field of arthroscopic human medicine, wherein the tendon fixation implant comprises a medial anchor (13), a lateral anchor (23) and a base plate (51), wherein the kit comprises a medial anchor inserter (10), wherein the medial anchor inserter (10) comprises a medial anchor drive spindle (11) and a medial anchor release tube (12), wherein the medial anchor release tube (12) is designed to receive the medial anchor drive spindle (11), wherein the medial anchor drive spindle (11) is designed to receive a medial anchor (13) and to introduce the medial anchor (13) into a bone, wherein the medial anchor drive spindle (11) has a locking head (16) for locking the medial anchor drive spindle (11) on the medial anchor release tube (12).

To provide new short chain oligopeptides, the use of such peptides in human medicine, and pharmaceutical compositions comprising them. Specifically, the invention provides for the use of these peptides and compositions in the treatment of, for example, inflammation.SOLUTION: Disclosed are peptide compounds having a specific amino acid sequence, and positional isomers, stereoisomers, and pharmaceutically or cosmetically acceptable salts of the peptide compounds. These compounds are particularly useful in the treatment of conditions characterized by inflammation, including wounds, burns, and disorders of the mucous membranes, such as anorectal disease, inflammatory bowel disease, gynecological disease, and dental disease.SELECTED DRAWING: Figure 1

A tool kit for minimally invasive implantation of a tendon fixation implant in the field of arthroscopic human medicine is provided. The tendon fixation implant includes a medial anchor, a lateral anchor, and a base plate. The tool kit includes a medial anchor inserter having a medial anchor drive mandrel and a medial anchor release tube. The medial anchor release tube is designed to receive the medial anchor drive mandrel. The medial anchor drive mandrel is designed both to receive a medial anchor and to introduce the medial anchor into bone by driving it into the latter. The medial anchor drive mandrel has a locking head for locking the medial anchor drive mandrel to the medial anchor release tube. The tool kit includes a base-plate inserter having a handpiece and a base-plate inserter tube designed to receive the base plate of the tendon fixation plate.

A simulated blood composition comprises a gelatinizable component and a gelatinizing component, said gelatinizable component comprising an alginic acid salt and a red colouring agent, and said gelatinizing component comprising a calcium salt. The gelatinizable component and the gelatinizing component are arranged for being brought into contact with each other at the time of use, so as to simulate the formation of a blood clot. The simulated blood composition can be made in the form of a kit, comprising the gelatinizable component and the gelatinizing component in solid or liquid form. The simulated blood composition can be used in combination with an anatomical simulator for veterinary medicine or human medicine, for example for simulating a venipuncture or a bleeding from a wound.

The invention belongs to the field of nano medicine, and particularly relates to a 20-nanometer DNA tetrahedron and a preparation method and application thereof.The 20-nanometer DNA tetrahedron is a double-strand DNA tetrahedron, the length of each arm is 8 DNA helixes, the 20-nanometer DNA tetrahedron has addressability, the 20-nanometer DNA tetrahedron is formed by self-assembling DNA single chains through multiple annealing procedures on the basis of the base pairing principle, and the 20-nanometer DNA tetrahedron is a double-strand DNA tetrahedron; the invention further discloses application of the 20-nanometer DNA tetrahedron in preparation of a skin repairing medicine. The problems that a DNA tetrahedron is poor in structural rigidity, weak in stability and low in activity are solved, a new technical scheme and a new treatment strategy are provided for the field of skin repair, and a new angle and a breakthrough are provided for development of human medical undertaking.

The present invention relates generally to human medicine, and more particularly to microRNA (miR)-replacement therapies for the treatment of venous thromboembolism (VTE). In particular, the present invention provides a pharmaceutical composition comprising a miR mimetic and a pharmaceutically acceptable carrier. The pharmaceutical compositions disclosed herein can be administered systemically, particularly by intravenous administration (IV).

Compositions and methods are disclosed for targeting the clustered protocadherins for therapeutic effect. More specifically, compositions and methods are disclosed to modify select isoforms in the α, β, and γ cluster to promote tissue regeneration or to target and reduce tumor burden in diverse cancer types. The methods have application in veterinary and human medicine.

The present invention generally relates to a method for preparing polyalkyleneimines, and to polyalkyleneimines obtainable by the method. The present invention further relates to particular polyalkyleneimines, and to the use of the polyalkyleneimines in human or veterinary medicine.

The invention discloses a manufacturing method of a high-simulation tendon aponeurosis model, which belongs to the technical field of human body medicine and animal teaching models, and comprises the following steps of: manufacturing a mold by overturning the mold, manufacturing a gel coat, closing the mold, pouring, opening the mold and trimming. According to the method, a real specimen is directly used as a model seed for model turning and copying, so that the problem of form distortion is avoided; materials used for injection molding are silicon rubber and white glass fibers or polypropylene fibers, the texture of the silicon rubber is similar to the hardness of a real specimen, and the fibers are arranged in longitudinal rows and embedded in the silicon rubber and are very similar to a real specimen in the aspect of anatomical observation; according to the invention, a real object specimen can be copied in form, and the texture and tissue structure are close to those of the real object specimen.

The present invention refers to novel compounds and their use as therapeutic agents in human medicine. The compounds of the present invention can be used in the treatment and / or prevention of a disease caused by and / or associated with insufficient TLX activity. Further, the present invention refers to a method of comprising administering an effective amount of the novel compounds.