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Method for the detection of bacterial endotoxins in a phagel filler
Pending
CN122109510A
Preparing sample for investigation
Biological testing
Biotechnology
Cellulose
The present application provides a kind of detection method of
bacterial endotoxin
in PHA gel filling agent.The filling agent of the present application comprises PHA microspheres, gel carrier
sodium
carboxymethyl cellulose
,
osmotic pressure
regulator
, pH
regulator
and water for injection, the present application systematically studies the influence of gel carrier and
osmotic pressure
regulator
on the performance of composition
shear viscosity
and
osmotic pressure
, and scientifically selects the excellent and stable gel prescription.The present application accidentally finds that the combination of water and a small amount of
dichloromethane
can realize the sufficient release of endotoxin, and accurately detect its content.The method of the present application can effectively ensure the safety of
human medicine
, and has important industrial value.
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Owner:
BEIJING MEIYAN SPACE BIOMEDICINE CO LTD
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Carboxymethyl cellulose
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Methyl cellulose
Sodium carboxymethylcellulose
Dichloromethane