The invention relates to a preparation for treating allergic rhinitis. The preparation is prepared by pressing a quick release layer and a sustained-release layer into
bilayer tablets and
coating, wherein the quick release layer consists of the following components in percentage by
mass: 1 to 10 percent of
levocetirizine hydrochloride, 1 to 15 percent of disintegrating agent, 0.5 to 3 percent of lubricating agent, 0 to 8 percent of
adhesive and the balance of filler; the sustained-release layer consists of the following components in percentage by
mass: 20 to 30 percent of
pseudoephedrine hydrochloride, 50 to 60 percent of sustained-release framework material, 0.5 to 3 percent of lubricating agent, 0 to 8 percent of
adhesive and the balance of filler; and the
mass ratio of the
levocetirizine hydrochloride to the
pseudoephedrine hydrochloride is 1:48. The sustained-release tablets for treating the allergic rhinitis have bright and clean surfaces, and the release behavior of the main
medicine pseudoephedrine hydrochloride of the sustained-release tablets has high consistency with that of American marketed
medicine cetirizine hydrochloride and
pseudoephedrine hydrochloride sustained-release tablets through detection; and the
dissolution rate of the main
medicine levocetirizine hydrochloride of the sustained-release tablets in 30 minutes is over 90 percent, so that the sustained-release preparation for treating the allergic rhinitis has high
bioavailability, a good
absorption effect, comprehensive and effective clinical curative effects, small side effects and ideal safety.