Medicine for treating child influenza and preparation method thereof

Abstract

The invention relates to a medicine for treating child influenza, which takes acetaminophen, pseudoephedrine hydrochloride and chlorphenamine maleate as main materials, and takes microcrystalline cellulose, starch, aspartame, sodium starch glycolate, magnesium stearate, 60% ethanol and 2% sodium starch glycolate aqueous solution as auxiliary materials. A preparation method is as follows: the acetaminophen, the pseudoephedrine hydrochloride and the chlorphenamine maleate are crushed into fine powder for spare use; the chlorphenamine maleate is uniformly mixed with the acetaminophen and the pseudoephedrine hydrochloride through a equivalent incremental method; parts of the microcrystalline cellulose, the starch, the aspartame and the sodium starch glycolate are weighed to be uniformly mixed, are crushed to sieve, and are mixed again, the 60% ethanol and the 2% sodium starch glycolate aqueous solution are added to the prepared mixture, are completely stirred to make a soft material, and wet particles are produced after the sieving; the produced wet particles are dried at 75 DEG C and granulated; after the granulation, the residual auxiliary materials of the microcrystalline cellulose, the starch, the sodium starch glycolate and the magnesium stearate are added again to mix uniformly; and dispersible tablets are pressed and packaged. The medicine has the advantages of obvious curative effect, good safety, convenience in medicine taking and suitable taste for children.

Description

technical field [0001] The invention relates to a medicament, in particular to a medicament for treating colds in children prepared by using chemical medicine as a raw material and a preparation method thereof. Background technique [0002] 1. From the perspective of the market environment and target groups, surveys have shown that among children under the age of 12, taking Western medicine to treat colds is still the first choice, and dispersants and syrup preparations with good taste are the most popular. Compared with adult cold medicines, the children's cold medicine market is relatively small, and there are relatively few brands to choose from; except for well-known brands such as Hutong and Eucadan, most of the common children's cold medicines are based on the successful experience of adult cold medicines generated on the basis of The most significant difference and characteristic between adult cold medicine and children's cold medicine is the ingredients and dosage. ...

AI Technical Summary

Problems solved by technology

According to statistical data, there are very few professional children's pharmaceutical factories in my country's pharmaceutical market at present, and the proportion of sick children in my country accounts for about 20% of the total sick population. less than 2% of children treated

[0004] 2. In terms of dosage forms, among the more than 3,000 types of pharmaceutical preparations commonly seen on the market, there are only more than 60 dosage forms for children

(2) Ordinary tablets and capsules are large in size, or often need to use multiple tablets (granules) at a time, especially for the treatment of the elderly, young and patients who have difficulty swallowing solids.

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