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Dispersible tablet for treating cold and its preparing process

A technology for dispersible tablets and colds, which is applied in the field of dispersible tablets for treating colds and its preparation technology, and can solve the problems of high incidence of colds

Inactive Publication Date: 2006-10-25
江西聚仁堂药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are only relatively many Chinese patent medicines and western medicines for the targeted treatment of colds in China, and the incidence of colds is relatively high in the population

Method used

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  • Dispersible tablet for treating cold and its preparing process

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Acetaminophen 325g Pseudoephedrine hydrochloride 30g

[0014] Dextromethorphan Hydrobromide 15g Chlorpheniramine Maleate 2g

[0015] The preparation method of the present invention: respectively pulverize acetaminophen, pseudoephedrine hydrochloride, dextromethorphan hydrobromide and chlorpheniramine maleate, pass through a 100-mesh sieve, and set aside. Weigh the prescription amount povidone K 30 , add an appropriate amount of water to prepare a 10% solution, as a binder, and set aside. Weigh the prescribed amount of paracetamol fine powder, pseudoephedrine hydrochloride fine powder, dextromethorphan hydrobromide fine powder, chlorpheniramine maleate fine powder, microcrystalline cellulose, low-substituted hydroxypropyl cellulose, aspirin For Patan, mix evenly with equal increments, add binder to make soft material, granulate with 35 mesh sieve, dry at 60°C, granulate with 35 mesh sieve, add prescription amount of crospovidone and micropowder silica gel , magnesium ...

Embodiment 2

[0017] Acetaminophen 325g Pseudoephedrine hydrochloride 30g

[0018] Dextromethorphan Hydrobromide 15g Chlorpheniramine Maleate 2g

[0019] The preparation method of the present invention: respectively pulverize acetaminophen, pseudoephedrine hydrochloride, dextromethorphan hydrobromide and chlorpheniramine maleate, pass through a 100-mesh sieve, and set aside. Weigh the prescription amount povidone K 30 , add an appropriate amount of water to prepare a 10% solution, as a binder, and set aside. Weigh the prescribed amount of paracetamol fine powder, pseudoephedrine hydrochloride fine powder, dextromethorphan hydrobromide fine powder, chlorpheniramine maleate fine powder, microcrystalline cellulose, low-substituted hydroxypropyl cellulose, aspirin For Patan, mix evenly with equal increments, add binder to make soft material, granulate with 35 mesh sieve, dry at 60°C, granulate with 35 mesh sieve, add prescription amount of crospovidone and micropowder silica gel , magnesium ...

Embodiment 3

[0021] Acetaminophen 325g Pseudoephedrine hydrochloride 30g

[0022] Dextromethorphan Hydrobromide 15g Chlorpheniramine Maleate 2g

[0023] The preparation method of the present invention: respectively pulverize acetaminophen, pseudoephedrine hydrochloride, dextromethorphan hydrobromide and chlorpheniramine maleate, pass through a 100-mesh sieve, and set aside. Weigh the prescription amount povidone K 30 , add an appropriate amount of water to prepare a 10% solution, as a binder, and set aside. Weigh the prescribed amount of paracetamol fine powder, pseudoephedrine hydrochloride fine powder, dextromethorphan hydrobromide fine powder, chlorpheniramine maleate fine powder, microcrystalline cellulose, low-substituted hydroxypropyl cellulose, aspirin For Patan, mix evenly with equal increments, add binder to make soft material, granulate with 35 mesh sieve, dry at 60°C, granulate with 35 mesh sieve, add prescription amount of crospovidone and micropowder silica gel , magnesium ...

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Abstract

The present invention relates to a dispersion tablet for curing common cold and its preparation process. Said invention is formed from main medicine including paracetamol, pseudoephedrine hydrochloride, dextromethorphan and chlorpheniramine maleate and auxiliary medicine including avicel, low-substituted hydroxypropyl cellulose, povidone K30, cross-linked povidone, aspartame, aspartame, micropowder silica gel and magnesium stearate.

Description

technical field [0001] The invention relates to a dispersible tablet for treating colds and a preparation process thereof. Background technique [0002] Phenomamin Tablets made of paracetamol, pseudoephedrine hydrochloride, dextromethorphan hydrobromide and chlorpheniramine maleate as the main raw materials are effective in treating and alleviating fever, headache, Sore limbs, sneezing, runny nose, stuffy nose, cough, sore throat and other symptoms have better curative effect. It is particularly important to redevelop the Chinese patent medicine Anmameimin Dispersible Tablets, because it has been found through research and clinical use that Fenmameimin Tablets have a long disintegration time, slow onset of action, and bioavailability to be improved. Children, the elderly and patients with dysphagia are also not suitable for use. inconvenient. However, changing to dispersible tablets has many advantages: high yield, low cost; accurate dosage, easy to car...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/485A61K9/20A61K31/137A61K31/167A61K31/4402A61P11/00A61P31/00
Inventor 胡乐平夏颖
Owner 江西聚仁堂药业有限公司
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