The application belongs to the technical field of
colloidal gold immunochromatography, and relates to
cetirizine monoclonal antibody,
nucleic acid molecules, vectors, detection kits and application thereof. The
cetirizine monoclonal antibody comprises a
heavy chain variable region and a light chain variable region, the
heavy chain variable region comprises VH-CDR1, VH-CDR2 and VH-CDR3, the light chain variable region comprises VL-CDR1, VL-CDR2 and VL-CDR3, the sequence of VH-CDR1 is shown as SEQ ID NO. 1, the sequence of VH-CDR2 is shown as SEQ ID NO. 2, and the sequence of VH-CDR3 is shown as SEQ ID NO. 3. The
monoclonal antibody of the application has high sensitivity to
cetirizine, the minimum
detection limit is 0.007 ng / mL, the quantitative range is 0.017-0.282 ng / mL, and the specificity is strong.