174results about How to "Non-addictive" patented technology

The present invention is flurbiprofen ester injection as antiphlogistic and analgetic medicine and its preparation process. Main medicine and supplementary material including solvent, emulsifier, isotonic agent, buffering agent and pH regulator are mixed to compound the injection. Compared with available oral flurbiprofen preparation, the flurbiprofen ester injection has even high curative effect, even fast action, long lasting effect and less stomach mucous membrane damage and other negative effect. The present invention is used in treating chronic rheumarthritis, etc and is especially suitable for relieve post-operational pain and pain caused by cancer, and it has high effect and no addiction.

The invention discloses the application of koumine to the preparation of medicines for treating chronic pains and belongs to the application of gelsemium alkaloid monomer. The analgesic experiments of the koumine on chronic pains of animals prove that the koumine has potent dose-dependent analgesic effect, the analgesic potency is superior to that of the classical antipyretic-analgesic and anti-inflammatory drugs which are aspirin and indomethacin, the therapeutic index of the koumine is much higher than that of the total alkaloids of gelsemium, the koumine possibly has no tolerance, no addiction and little side effect, which indicates that the koumine has potent and low-toxicity analgesic effect, the mechanism of action of the koumine is possibly different from those of clinically common opium analgesics or aspirin analgesics, the koumine and the pharmaceutically acceptable salt thereof have the application of preparing of the medicines for treating chronic pains and have no serious disadvantages of the clinically common analgesics and can be developed into a novel analgesic which has potent analgesic effect in treating chronic pains such as inflammatory pain, neuropathic pain, cancer pain and the like, has no tolerance and addiction and little side effect, thus the koumine has bright industrialization prospect.

The invention belongs to the field of cigarettes, and particularly relates to a herbal tea cigarette. The herbal tea cigarette is prepared in the six steps of material selection, silk making, impurity removal and roasting, mixing fermentation, drying and finished product obtaining. Pseudo-ginseng leaves and lotus leaves are natural herbal plants beneficial to human, have unique flavor after being roasted, and can reduce the bitterness of tea leaves after being mixed with the tea leaves; after momordica grosvenori fruit pulp is added, the bitterness of the tea leaves can be further reduced, the sweetness of the herbal tea cigarette is increased, the herbal tea cigarette is soft in taste, the effects of clearing lung and relieving sore-throat can be achieved, and a smoker does not generate phlegm or cough. The herbal tea cigarette is free of nicotine and cigarette tar, thus is harmless to the human body, and can gradually replace a traditional cigarette to help users to reduce the use of traditional cigarettes, and the smoking cessation effect is obvious.

The invention discloses new application of a natural product amentoflavone in treating cancers. The natural product amentoflavone is extracted from plants, Chinese medicinal materials or Chinese medicaments prepared in ready-to-use forms containing the amentoflavone. The compound serves as a pharmacodynamic component to prepare medicament preparations for treating the cancers, and can be independently or combined with an excipient acceptable in the pharmaceutical technology to be prepared into the medicament preparations such as tablets, capsules, granules, sustained release preparations and pills for oral administration, gels and suppositories administrating through orifices such as vagina, anus and nasal cavity, and intramuscular or intravenous injections. The content of the amentoflavone in the medicament preparations is over 90 percent. The invention discloses the pharmacodynamic component of a Chinese medicament tamariskoid spikemoss herb for treating the cancers, and provides a scientific basis for clinical application, so the amentoflavone can serve as a natural anticancer agent and has the characteristics of no addiction and low dosage.

The invention discloses a nutrition composition and application thereof. The nutrition composition comprises the following active ingredients in percentage by weight: 5-94.7 percent of calcium, 0.0001-0.02 percent of vitamin k, 5-94.7 percent of oil and 0.01-0.4 percent of antioxidant. The nutrition composition greatly enhances the bioavailability of the calcium, has multiple health care functions, and has obvious functions on controlling cancers, cardiac, cerebral and vascular diseases, diabetes, rheumatic disease, dermatitis, depression, dementia praecox, Alzheimer's disease, allergy, asthma, nephropathy, senium and chronic obstructive pulmonary disease, enhancing intelligence and immunity, protecting eyesight, promoting skeleton growth and preventing osteoporosis, thereby being suitable for being taken by various people and being a difunctional product which has the function of calcium and memory simultaneous supplement and can satisfy the need by the development of infant body and brain.

The invention discloses applications of gelsemine, koumine and 1-methoxyl gelsemine to the preparation of a medicine for treating the anxiety, especially an application of gelsemium alkaloid monomer gelsemine as the sole active ingredient or a pharmaceutically acceptable salt thereof to the preparation of the medicine for treating the anxiety, an application of gelsemium alkaloid monomer koumine as the sole active ingredient or the pharmaceutically acceptable salt thereof to the preparation of the medicine for treating the anxiety, and an application of gelsemium alkaloid monomer 1-methoxyl gelsemine as the sole active ingredient or the pharmaceutically acceptable salt thereof to the preparation of the medicine for treating the anxiety; and the gelsemine, the koumine and the 1-methoxyl gelsemine can play significant roles in treating the murine anxiety in far below the toxic dose so that the safe therapeutic window is remarkable expanded, have no tolerance, low addiction and side effect, and are more suitable for the preparation of the medicine for treating the anxiety in comparison with gelsemium total alkaloids.

The invention discloses application of geranylgeranylacetone to the preparation of a medicament for preventing and/or treating opiates drug addiction, relating to the technical field of medicines. Geranylgeranylacetone is taken as a medicament for preventing and treating the opiates drug addiction or is used for preparing a medicament for preventing and treating the opiates drug addiction. One or more medicinally acceptable conventional medicinal auxiliary materials can also be added into geranylgeranylacetone to prepare capsules, pills, powder, tablets, granules, oral liquids, injections and the like. Geranylgeranylacetone has the effects of antagonizing conditioned place preference behaviors caused by morphine and increase in autonomic activities induced by morphine and relieving the function of abstinence symptom action, is used for preventing and treating the opiates drug addiction, and has the advantages of remarkable curative effect, high safety, addiction resistance, low price, capability of lowering the economic burden of a patient, and the like.

The invention relates to a composition with effects of alleviating a hangover and protecting the liver. The composition comprises synanthrin, xylitol, aminopropionic acid and glutamine. Particularly, the composition disclosed by the invention comprises 8 parts by weight of synanthrin, 30-50 parts by weight of xylitol, 15-35 parts by weight of aminopropionic acid and 15-35 parts by weight of glutamine. The composition disclosed by the invention has good chemical property and biological property.

The invention discloses a device used for treating poor sleeping quality. The device is an ultralow frequency transcranial magnetic stimulation device and comprises a control circuit and a stimulation coil, wherein the stimulation coil is controlled by the control circuit to emit 3mHz, 7mHz and 11mHz magnetic fields. According to the ultralow frequency transcranial magnetic stimulation device, the 3mHz, 7mHz and 11mHz magnetic fields are employed and are exerted on a brain, so the sleeping quality of a patient can be obviously improved. An effective rate for improving the sleeping quality reaches up to 90% and is far higher than 60-70% through drug treatment, and the device has no side effects.

The invention relates to an application of bulleyaconitine A used for preparing medicine for treating pain related to a Nachannel, belonging to medicine containing effective organic ingredients, in particular to medicine using the bulleyaconitine A for treating a disease. The medicine contains excipient which plays roles in padding, bond, disintegration and lubrication; the bulleyaconitine A and the excipient are mixed to be pressed into tablets; and each tablet of bulleyaconitine A contains 0.1mg to 0.5mg of the bulleyaconitine A. The medicine plays obvious roles in resisting pain and inflammation and improving rationalization indexes for wide sodion pain, such as rheumathritis, osteoarthritis, scapulohumeral periarthritis, lumbodorsal fascia inflammation, strain of lumbar muscles, sprain of joints, closed fracture of limbs, sprain, toothache, and the like. The medicine can be rapidly absorbed by oral administration, eliminates the half-life for about 5 hours, and has an excretion pathway by two channels and little toxicity. Compared with opium medicine, the medicine does not generate a tolerant phenomenon in the course of resisting pain, causes no addiction and is convenient for treatment and use as an oral administration preparation.

The invention provides a cancer pain plaster composed of nux vomica, Hindu datura flower, pendulous monkshood root, dried Chinese toad skin, paniculate swallowwort root or herb, yanhusuo tuber, panax notoginseng, and an auxiliary material of borneol. One plaster comprises, preferably, 1.0g of nux vomica, 1.0g of Hindu datura flower, 1.0g of pendulous monkshood root, 1.0g of dried Chinese toad skin, 1.0g of paniculate swallowwort root or herb, 2.0g of yanhusuo tuber, 1.0g of panax notoginseng, and the auxiliary material of borneol. According to the technology, authentic pure traditional Chinese medicines are selected, and scientific formulation and rigorous production process are adopted. The materials are refined, and effect is concentrated. An effect can be provided after 20min of application, and a pain-relieving effect can last for 24h. Therefore, a substantial pain-relieving effect can be provided for continuous cancer pain. Especially, the plaster has relieving and stopping effects against long-term severe pains. When the plaster is repeatedly applied, no toxic or side effect is provided, and addiction is prevented. The plaster causes no irritation or allergy to skins, and is suitable to be used against various pains caused by various cancer primary tumors and metastases. With the plaster, patient pain can be relieved, symptoms can be relieved, and substantial pain relieving effects and concentrated pain relieving functions such as blood circulation activating, stasis removing, collateral dredging, qi regulating, and stagnation eliminating are provided.

The invention discloses a composition having efficacy of reducing weight. Through guidance under a traditional Chinese medicine theory, a formula consisting of medicinal and edible traditional Chinesemedicines, high-function fruits and vegetables and natural ingredients is adopted, a medicinal and edible traditional Chinese medicine compound recipe is used for wholly and systematically conditioning bodies and improving obesity constitutions, the high-function fruits and vegetables and the natural ingredients can quickly supplement fat metabolism accelerating factors, satiety factors and intestinal tract prebiotics for organisms, the medicinal and edible traditional Chinese medicines, the high-function fruits and vegetables and the natural ingredients are in organic collocation for whollyconditioning the organisms and treating both manifestation and root causes of diseases, the composition is safe, free from addiction and high in speed of taking effects, achieves the purposes of elevating clear Qi to lower turbid Qi, eliminating phlegm, humidity and blood stasis, removing fat, invigorating pulse and enabling internal organs to be smooth, and achieves the efficacy of reducing weight. The composition consists of natural food ingredients, is free from dependence, free from toxic and side effects and high in safety. Besides, the composition has good mouth feel, anorexia cannot becaused, the mouth feel of foods can be adjusted, the composition can be made into foods of beverages, biscuits, pastries, sweets and the like, the efficacy of reducing weight can be realized, and thecomposition is convenient to carry and eat.

The present invention provides plant nutrient drink having functions of preventing fatigue and losing weight and a preparation technology thereof. Every 1,000 ml of the plant nutrient drink is prepared from the following raw and accessory materials in parts by weight: at least one kind of 20.0-120.0 g of fresh Chinese wolfberry fruits, 4.0-20.0 g of dried Chinese wolfberry fruits and 6.0-48.0 g of radix astragali decoction pieces, 0.05-150.0 g of a sweetener, 2.7-3.3 g of a pH value stabilizer, 0.0006-22.2 g of nutrients, 0-0.100 g of a pigment, 0-0.10 g of a flavoring agent, and the balance water. The preparation technology comprises single or compound prescription pretreatment liquid of Chinese wolfberry fruits and radix astragali preparing, blending, homogenizing, pre-sterilizing, filling, post-disinfecting, outer packaging, factory inspecting, etc. The prepared compound health-care sports drink has health-care functions of preventing fatigue, losing weight, preventing oxidation, enhancing body immunity and helping lower lipids, supplements nutrition, can quickly, significantly and enduringly relieve fatigue feelings of athletes, easily fatigued people, people in sub-health statuses and populations with over mental and physical labor, helps obese people to lose weight, and is good in taste, rich in nutrition, advanced in technologies, free of stimulants and preservatives, and suitable for large quantities of drinking.

A medicinal cigarette for dropping drug is prepared from 13 Chinese-medicinal materials including honeysuckle flower, red sage root, Chinese angelica root, astragalus root, etc. Its advantages are high curative effect, quickly taking its effect and no addiction.

The invention relates to a production process for a carbocisteine buccal tablet. The production process comprises the following steps: crushing and sieving of raw and accessory materials; weighing and batching; mixing and granulating; drying; size stabilization; total blending; tableting; packaging; and warehousing. The carbocisteine buccal tablet produced in the invention is used for cough and difficult expectoration caused by chronic bronchitis and bronchial asthma mucus; in the production process of the carbocisteine buccal tablet, crushing granularity of the main material--carbocisteine is strictly controlled so as to ensure that all the main material is crushed and sieved with a 100-mesh sieve, and control of raw material granularity provides prerequisites for rapid absorption of the carbocisteine buccal tablet; and a high-grade material of the industry is a binder, so the appearance of the tablet surface is beautiful and rapid arrival of a drug at a designated position can be promoted.

The invention discloses a pharmaceutical composition for nourishing heart, tranquillization, strengthening spleen and benefiting qi, and the active ingredients of the composition are prepared by extracting more than ten medicinal materials of pilose Asiabell root, rehmannia root, platycladi seed, membranous milkvetch root, thinleaf milkwort root-bark, amur corktree bark, Szechuan lovage rhizome, common macrocarpium fruit, tuber fleeceflower stem, costustoot, fossilizid (calcined), common anemarrhena rhizome, dwarf lilyturf tuber, sharpleaf galangal fruit and the like. The unique medicinal active ingredients in the pharmaceutical composition have the efficacies of regulating qi, resolving stagnation, eliminating phlegm, inducing resuscitation, nourishing yin and blood, nourishing heart, tranquillization, strengthening spleen and benefiting qi. The pharmaceutical composition is used for treating neurasthenia, such as palpitation, insomnia, multiple dreams, upset, chest tightness, shortness of breath, irritability and anxiety.

The invention discloses the application of gelsenicine to the preparation of medicines for treating chronic pains and belongs to the application of gelsemium alkaloid monomer. The analgesic experiments of the gelsenicine on chronic pains of animals prove that the gelsenicine has potent dose-dependent analgesic effect, the analgesic potency is superior to that of the classical antipyretic-analgesic and anti-inflammatory drugs which are aspirin and indomethacin, the therapeutic index of the gelsenicine is much higher than that of the total alkaloids of gelsemium, the gelsenicine possibly has no tolerance, no addiction and little side effect, which indicates that the gelsenicine has potent and low-toxicity analgesic effect, the mechanism of action of the gelsenicine is possibly different from those of the clinically common opium analgesics or aspirin analgesics, the gelsenicine and the pharmaceutically acceptable salt thereof have the application of preparing of the medicines for treating chronic pains and have no serious disadvantages of the clinically common analgesics and can be developed into a novel analgesic which has potent analgesic effect in treating chronic pains such as inflammatory pain, neuropathic pain, cancer pain and on the like, has no tolerance and addiction and little side effect, thus the gelsenicine has bright industrialization prospect.