46 results about "Asthmatic bronchitis" patented technology

The invention belongs to the technical field of medicine, and particularly relates to an amorphous ambroxol hydrochloride compound and a preparation method thereof. The amorphous ambroxol hydrochloride compound has high purity and stability, does not have obvious moisture absorption and weight increase even under the condition of high humidity, ensures that relative substances do not grow, and has higher dissolution rate than crystalline ambroxol hydrochloride. The invention also relates to an application of the amorphous ambroxol hydrochloride compound in preparation of medicine for the treatment of acute and chronic pulmonary diseases with the symptom of ropy sputum and difficult expectoration, phlegm eliminating treatment of acute exacerbation of chronic bronchitis, asthmatic bronchitis and bronchial asthma, prophylactic treatment of lung complication after an operation, and treatment of infant respiratory distress syndrome (IRDS) of premature infants and neonates.

The invention relates to a levalbuterol hydrochloride orally disintegrating tablet and the preparation method; wherein the levalbuterol hydrochloride orally disintegrating tablet comprises an active pharmaceutical ingredient, the levalbuterol hydrochloride, and pharmaceutical necessities. The pharmaceutical necessities include a disintegrant, a filling agent, a masking agent and a corrective. The raw material ingredients calculated by weight ratio are 0.79-2.5 per cent levalbuterol hydrochloride, 50-60 percent disintegrant, 20-40 per cent filling agent, 1.58-10 per cent masking agent and 10-12 per cent corrective, which are made into the orally disintegrating tablets by direct powder compression process. The tablets of the invention is taken easily without water, disintegrated quickly and takes effect quickly, high in bioavailability, less stimulatory function to gastrointestinal tract, and applicable to prevention and cure of bronchial asthma, asthmatic bronchitis, and bronchospasm of an emphysema patient.

A portable rescue inhaler having a first canister containing a gas mixture of helium, oxygen, and nitrogen, and having a second canister containing an aerosolized medicine. The gas mixture of helium, oxygen, and nitrogen contained in the first canister has a density slightly lower than the density of atmospheric air. The portable rescue inhaler is capable of delivering the lower density gas mixture simultaneously with the aerosolized medicine for emergency hand held rescue of patients suffering from asthma, asthmatic bronchitis, COPD, emphysema, cystic fibrosis, and myocardial insufficiency. The portable rescue inhaler is capable of providing a vaporized anesthetic for greater medical assistance for patients in need of anesthesia due to respiratory insufficiency. The portable rescue inhaler reduces intra-operative risks in respiratory patients prior to gaining access to a hospital or care center.

The invention provides a tablet containing ambroxol hydrochloride and salbutamol sulfate, and belongs to the technical field of medicines. The tablet provided by the invention mainly comprises the following auxiliary materials: a filler, a disintegrating agent, a lubricant and an adhesive. The tablet provided by the invention is capable of treating diseases of a respiratory system, such as acute and chronic bronchitis, asthmatic bronchitis and bronchial asthma; sputum is easy to cough up when trachea is expanded; the tablet is simple in prescription, and good in curative effect; and the preparation technology is suitable for industrialized mass production.

The invention discloses a pharmaceutical composition for relieving cough and asthma. The pharmaceutical composition consists of the following materials: 6-18 parts of semen armeniacae amarae, 6-18 parts of perilla fruits, 15-28 parts of radix stemonae, 15-28 parts of tussilago farfara, 10-24 parts of aster, 10-24 parts of birthwort, 10-24 parts of loquat leaves, 6-18 parts of white mulberry root-barks, 8-16 parts of semen lepidii, 2-10 parts of ginkgoes, 2-10 parts of ginkgoes, 2-10 parts of ardisia japonica, 2-10 parts of flos daturae, 8-16 parts of physochlaina macrophylla, 15-28 parts of folium rhododendri daurici, 22-38 parts of thorny elaeagnus leaves, and 10-24 parts of momordica grosvenori. A dosage form of the pharmaceutical composition can be medically acceptable dosage forms such as capsule, tablet, spray and decoction, wherein the preparation method for the dosage forms and dosage amount of auxiliary materials are carried out according to the normal process. The pharmaceutical composition disclosed by the invention overcomes the defects of the existing drugs for relieving cough and asthma; the pharmaceutical composition with good effects for treating bronchitis and asthmatic bronchitis is provided, curative effect temperature and toxic and side effect are relatively lower.

The invention relates to a formula of a compound medicine preparation for relieving cough and preventing asthma and a preparation method thereof. The formula mainly comprises the following components in parts by weight: 5-25 parts of methoxyphenamine hydrochloride, 3-15 parts of narcotine, 10-50 parts of aminophylline, 0.1-2 parts of ketotifen fumarate, and an appropriate amount of pharmaceutically acceptable auxiliary materials. In the invention, the methoxyphenamine hydrochloride, the narcotine, the aminophylline and the ketotifen fumarate are prepared into the compound medicine preparation for the first time; and the obtained compound medicine preparation has more obvious treatment effect on diseases such as cough, asthma, bronchial asthma, asthmatic bronchitis and the like; combination of the ketotifen fumarate and the aminophylline in the formula can enhance the bronchiectasis action of the aminophylline; and the mild sedation of the ketotifen fumarate can simultaneously counteract the central nervous system stimulation action caused by the aminophylline.

The invention relates to procaterol hydrochloride pharmaceutical granules, which have an effect of relieving asthma, and a preparation process of the granules. The procaterol hydrochloride granules belong to an orally rapidly dispersible preparation which is prepared from procaterol hydrochloride and medicinal pharmaceutical excipients, and the preparation is suitable for treating bronchial asthma, asthmatic bronchitis and chronic obstructive pulmonary disease. According to the invention, the prepared granule medicine is rapid to be dissolved and uniform to be dispersed; the medicine can be taken after being dissolved in water and the medicine can be directly taken without water as well; the medicine is delicate and sweet in taste; the medicine is capable of effectively overcoming medication rejecting psychology of patients and meeting a medication requirement during an asthma acute attacking period, and the medicine is especially suitable for children, old people or patients having difficulty in swallowing. Upon detection, the procaterol hydrochloride granules prepared by the invention are quite excellent in static dissolubility, and are obviously better than a preparation of a conventional process in content uniformity; and the procaterol hydrochloride granules effectively guarantee the timeliness, the safety and the effectiveness of clinical treatment, and the procaterol hydrochloride granules are quite high in value of popularization.

The invention discloses an external use novel plaster phlegm-eliminating asthma-preventing cough-relieving Guben electuary for curing, comprising the following raw materials of traditional Chinese medicine stemona, pinelliae, almond, shursee, schisandrae Chinensis, coltsfoot flower, daturaflower, semenpsoraleae, placenta hominis, Chinese angelica, novel plaster matrix and antioxidant propyl gallate (PG). The phlegm-eliminating asthma-preventing cough-relieving Guben electuary has fine curing effect on chronic bronchitis and asthmatic bronchitis.

The invention discloses a drug for treatment of asthmatic bronchitis, which is prepared by taking ephedra, almond mud, gypsum, caulis perillae, platycodon, couchgrass root, green forsythia and cortex moutan radicis as raw materials. The invention has good use effect, accurate curative effect and the effective rate of over 65%.

A portable rescue inhaler having a first canister containing a gas mixture of helium, oxygen, and nitrogen, and having a second canister containing an aerosolized medicine. The gas mixture of helium, oxygen, and nitrogen contained in the first canister has a density slightly lower than the density of atmospheric air. The portable rescue inhaler is capable of delivering the lower density gas mixture simultaneously with the aerosolized medicine for emergency hand held rescue of patients suffering from asthma, asthmatic bronchitis, COPD, emphysema, cystic fibrosis, and myocardial insufficiency. The portable rescue inhaler is capable of providing a vaporized anesthetic for greater medical assistance for patients in need of anesthesia due to respiratory insufficiency. The portable rescue inhaler reduces intra-operative risks in respiratory patients prior to gaining access to a hospital or care center.

The invention discloses traditional Chinese medicine inhalation aerosol for treating asthma. The traditional Chinese medicine inhalation aerosol for treating asthma is prepared from, by weight, 5%-69.5% of effective ingredients obtained from ephedra, flos daturae, fructus forsythia and semen armeniacae amarae through water extraction and alcohol precipitation, 0%-30% of cosolvent, 0.5%-2% of solutizer and 30%-90% of propellant. The traditional Chinese medicine inhalation aerosol for treating asthma has the effects of freeing the lung and relieving asthma, and expelling phlegm to arrest coughs, is clinically used for asthma caused by turbid phlegm lung obstructing and impairment of dispersing and descending function of the lung, coughs, and chest oppression and excessive phlegm; bronchial asthma and asthmatic bronchitis have the syndromes. Compared with an existing preparation, the traditional Chinese medicine inhalation aerosol directly enters the lung, and has the advantages of being rapid in effect taking, efficient and the like.

The invention relates to a traditional Chinese medicine preparation for treating acute asthmatic bronchitis. A traditional Chinese medicine preparation for treating wind-cold asthma is provided aiming at treating acute cough and asthma, wheezing in the throat, fever with cold aversion, soreness and pain of the whole body, adiaphoresis, less or no production of phlegm and acute asthmatic bronchitis caused after patients suffer externally-infected wind-cold, and the whole prescription is formulated according to monarch, minister, assistant and guide modes. According to the prescription, prepared ephedra herb is taken as a monarch medicine, and cassia twig, white paeony root, manchurian wildginger, unibract fritillary bulb, cicada slough, Chinese thorowax root, root of lobed kudzuvine, officinal magnolia bark, immature bitter orange and aprieot seeds are taken as ministerial medicines; gypsum, fineleaf schizonepeta herb, divaricate saposhnikovia root, indigowoad root, paniculate swallowwort root, root of sinkiang arnebia, baikal skullcap root, great burdock achene, turmeric root-tuber and baikal skullcap root are taken as assistant medicines; and liquorice root is taken as a guide medicine. The whole prescription disclosed by the invention is compatible, has the effects of dispelling cold and relieving exterior, and relieving cough and preventing asthma, and has significant treatment effects on symptoms such as cough and asthma caused after patients suffer externally-infected wind-cold. The traditional Chinese medicine preparation disclosed by the invention can be applied to clinical mastering of indications, cannot cause obvious adverse effects, and has the effective rate of more than 90%.

The invention discloses a medicine used for treating asthmatic bronchitis and a preparation method thereof. The medicine is prepared from the following raw materials in parts by weight: 30-90 of fragrant dahurian angelica root, 30-90 of Indian damnacanthus, 30-90 of Japanese ardisia, 16-50 of momordica grosvenori and 10-40 of water pseudo-ginseng. The preparation method of the medicine comprises the following steps: firstly, taking 40% of fragrant dahurian angelica root and 40% of water pseudo-ginseng respectively, pulverizing into fine powder, then taking the residual fragrant dahurian angelica root, the residual water pseudo-ginseng and the rest three raw materials of the Japanese ardisia, the momordica grosvenori and the Indian damnacanthus, adding water, decocting, filtering, concentrating into the shape of a thick paste and adding the fine powder and a right amount of auxiliary materials to prepare tablets, hard capsules or granules. All the medicinal materials selected by the invention are purely natural plant medicines and have no toxic or side effect to a human body, the invention has the effects of reducing fever, resolving phlegm, diminishing inflammation, alleviating pain and relieving cough and asthma and has obvious curative effect for treating tracheitis and asthmatic bronchitis, and the total effective rate reaches 90.2%.

The invention relates to a traditional Chinese medicinal composition for tonifying qi, astringing lung, relieving cough and asthma and warming phlegm and retained fluid and a preparation method thereof. The traditional Chinese medicinal composition is prepared from nine traditional Chinese medicines, namely dried toad, astragalus root, ginkgo, aster tataricus, bitter apricot seed, whiteflower hogfennel root, prepared common monkshood daughter root, Chinese magnoliavine fruit and black pepper; the traditional Chinese medicinal composition has effects of tonifying qi, astringing lung, relievingcough and asthma and warming phlegm and retained fluid, is mainly used for lung deficiency cough, asthma with abundance of phlegm, senile chronic trachitis and emphysema, is more suitable for asthmatic bronchitis, and has prevention effect on repeated cold. Compared with the prior art, the traditional Chinese medicinal composition has the advantages that: the process is more reasonable, the effect in a clinical pharmacodynamic test is obviously improved, the bioavailability is high, the medicinal stability is high, and the traditional Chinese medicinal composition does not have any toxic or side effect.

The invention discloses a fructus-trichosanthis phlegm-resolving binds-disspitating cough-suppressing panting-calming instant granule. Fructus-trichosanthis and bulbus fritillariae thunbergii are employed as sovereign medicines, and fructus aurantii, radix platycodonis, pericarpium citri reticulatae, rhizoma pinelliae preparatum, poria, fried rhizoma atractylodis macrocephalae and raw radix glycyrrhizae are employed as auxiliary materials, and steps of extraction, concentration drying, preparation of a soft material, pelletization, drying, particle finishing, sterilization and packaging are performed, so that the instant granule is prepared. The instant granule has the efficacy of clearing heat and detoxifying, dispelling dampness and dissipating binds, moistening lung and resolving phlegm, is capable of effectively alleviating and eliminating asthma and various symptoms caused by asthma, also has substantial treatment effect on allergic bronchial asthma, asthmatic bronchitis and various asthma symptoms caused by other causes, is fast in effectiveness, short in treatment course and free of side effect, and has the effective rate of 100%.

The present invention relates to a pure Chinese medicine preparation for effectively curing asthmatic bronchitis with obvious therapeutic effect. Said Chinese medicine is made up by using 9 Chinese medicinal materials of salvia root, ephedra, earthworm, scutellaria root, white peony root, licorice and others through a certain preparation process.

The invention discloses a traditional Chinese medicine composition for treating asthmatic bronchitis, which is prepared from the following raw materials in parts by weight: 11-13 parts of ginseng, 14-16 parts of fritillaria cirrhosa, 16-20 parts of donkey-hide gelatin, 18-22 parts of dangshen, 17-19 parts of radix rehmanniae preparata, 11-13 parts of radix ophiopogonis, 11-13 parts of himalayan teasel root, 11-13 parts of galingale, 14-16 parts of cassia twig, 11-13 parts of cinnamon, 18-22 parts of ginger processed pinellia, 11-13 parts of Pumice Stone, 11-13 parts of sweet almond, 11-13 parts of Limonium bicolor and 11-13 parts of Anemone dichotoma L. The composition is decocted with water into a decoction and taken orally. The traditional Chinese medicine composition has the characteristics of short treatment period and obvious treatment effect.

The invention discloses traditional Chinese medicine dressing for treating infant asthmatic bronchitis. The infant asthmatic bronchitis belongs to the traditional Chinese medicine asthma category, is commonly seen in the infantile period, and has the characteristics of paroxysmal wheezing anhelation and prolonged expiration. According to pathogenesis, traditional Chinese medicine of lacebark pine cones, fomes officinalis ames, archontophoenix alexandrae, Japanese helwingia roots, mountain pepper roots, nervilia fordii, rigidleaf cymbidium fruits, herbs of pubescent blumea, corniculate lotus, elaeagnus umbellate, angelica citriodora hance and yangchun amomum flowers with the effects of inducing mild diaphoresis, releasing the lung, clearing heat, soothing the lung, reducing phlegm and stopping asthma is selected, so that the dressing is prepared. Through clinical tests, the total effective rate reaches 96.8% and obviously superior to that of a control group, and side effects are fewer.

The invention discloses a traditional Chinese medicine composition for treating asthmatic bronchitis. The traditional Chinese medicine composition is mainly prepared from the following traditional Chinese medicinal materials in parts by weight: 35-55 parts of semen brassicae, 20-40 parts of perillaseeds, 5-20 parts of radix codonopsis, 5-10 parts of liquorice, 5-20 parts of coptis chinensisand 2-5 parts of pinellia ternate. The traditional Chinese medicine composition has an excellent effect on treatment of asthmatic bronchitis, does not have an adverse effect basically and is suitable for patients with asthmatic bronchitis for taking in treatment.

The invention provides a medicine for treating cough caused by respiratory system diseases and a preparation method thereof. The pharmaceutical composition is prepared from the following raw medicines in parts by weight: 5 to 7.5 parts of methoxyphenamine hydrochloride, 10 to 15 parts of aminophylline, 2.8 to 4.2 parts of narcotine, 0.8 to 1.2 parts of chlorpheniramine maleate and 20 to 30 parts of cimetidine. The medicine for treating the cough caused by the respiratory system diseases can be obtained by taking the raw medicines in corresponding parts, adding auxiliary materials according to a conventional preparation method of pharmaceutics and preparing into dosage forms such as tablets or capsules, dry suspensions, granules, solutions, syrup and the like. The compound preparation is prepared from methoxyphenamine hydrochloride, aminophylline, narcotine, chlorpheniramine maleate and cimetidine, and is used for treating symptoms such as cough, expectoration, wheeze and the like caused by bronchial asthma, asthmatic bronchitis and other respiratory system diseases. The pharmaceutical curative effects of methoxyphenamine hydrochloride, aminophylline and narcotine can be improved, and adverse drug reactions are reduced.

The invention relates to a pharmaceutical composition, which comprises amoxicillin or amoxicillin sodium salt, a β-lactamase inhibitor and ambroxol or ambroxol hydrochloride in an effective dose. The pharmaceutical composition of the present invention shows significant synergistic effect, can effectively inhibit the activity of β-lactamase, enhance the antibacterial activity of amoxicillin, solve the problem of drug resistance, increase the drug concentration of antibiotics in the respiratory tract, and enhance the antibacterial effect. It strengthens the results of treatment, improves curative effect, shortens the course of disease, and has the advantages of accurate dosage and convenient clinical application. The present invention is effective for respiratory diseases such as acute and chronic respiratory infections with abnormal secretion, especially acute bronchitis, asthmatic bronchitis, acute exacerbation of chronic bronchitis, bronchiectasis and bronchial asthma, as well as otitis media, pharyngitis, sinusitis, pneumonia and Tonsillitis has a good therapeutic effect.

The invention belongs to the technical field of medicines, and relates to an inhalable pharmaceutical composition containing procaterol hydrochloride. The inhalable pharmaceutical composition comprises procaterol hydrochloride and one or more pharmaceutic adjuvants suitable for inhalation administration. The inhalable pharmaceutical composition can be used for treating diseases such as bronchial asthma, asthmatic bronchitis, acute bronchitis accompanied with increased bronchial reactivity, chronic obstructive pulmonary disease (COPD) and the like.

The invention provides application of a compound Haqing injection in preparing a drug for treating diseases of a respiratory system. The drug is formed by the compound Haqing injection and one or a combination of Ruyi anti-asthma pills and lidocaine. The drug is used for acupoint injection to treat one or multiple diseases of a cold, acute and chronic bronchitis, a chronic obstructive pulmonary disease, emphysema, a pulmonary heart disease, asthmatic bronchitis, bronchopneumonia, interstitial pneumonia and cough variant asthma. It is proved through experimental results of clinical cases that the drug for acupoint injection is significant in curative effect on the diseases of the respiratory system and particularly obvious in curative effect on the diseases such as the chronic obstructive pulmonary disease and cough variant asthma.

The invention discloses a composition for treatment of asthma and asthmatic bronchitis and a preparation method thereof, wherein the composition comprises the following raw materials in parts by weight: 15-30 parts of gingko, 5-40 parts of perillaseed, 10-40 parts of flos farfarae, 10-50 parts of herba ephedra, 10-30 parts of pinellia ternata, 5-20 parts of mulberry bark, 5-25 parts of apricot kernel, 10-35 parts of radix scutellariae, 4-15 parts of liquorice, 5-13 parts of borneol, 20-35 parts of folium artemisiae argyi, 5-20 parts of semen lepidii, 10-35 parts of semen brassicae, 20-35 partsof endothelium corneum gigeriae galli, 10-30 parts of pericarpium citri reticulatae, 5-20 parts of mint leaves, 2-10 parts of radix astragali, 5-20 parts of wizened scutellaria and 10-25 parts of trichosanthes kirilowii maxim. Through synergism of various raw materials, the prepared finished product has good effects of relieving lung, relieving asthma, clearing heat and resolving phlegm, has goodtreatment effect on bronchial asthma, acute bronchitis, acute attack of chronic bronchitis, upper asthma, saliva in larynx and voicelessness and the like, has no toxic or side effects and allows diseases not to relapse.

The present invention pertains to the art of medicine, in particular to a compound for curing asthmatic bronchitis and bronchial asthma. The compound is made from the following raw materials: 1 to 5 portions of Chinese ephedra, 3 to 7 portions of honeysuckle, 1 to 5 portions of hogfennel root, 5 to 9 portions of dyer woad leaf, 5-9 portions of dandelion, 3 to 7 portions of prepared pinellia tuber, 2 to 6 portions of inula flower and 3 to 7 portions of chuanxikong rhizme. The present invention also relates to a gel preparation method of the compound, including (1) the crude drugs are taken in proportion, added with water and undergone moving warm extract for twice, and the drug liquid is condensed, thus obtaining the warm concentrated solution; (2) 5 to 20 percent chitosan solution is added into the warm concentrated solution, placed overnight, eccentrified and filtered, decompressed and condensed to the relative density 1.34, thus obtaining the chitosan solution; (3) 3 to 8 percent crylic acidresin II is added into the chitosan solution, stirred for adjusting pH to 7.2, placed for gelation and subpackaged.

The invention discloses medicine for treating cough variant asthma. The medicine is prepared from 5 to 15 weight parts of radix crepis rigescens, 3 to 10 weight parts of fritillary bulb, 5 to 12 weight parts of semen armeniacae amarae, 5 to 12 weight parts of perilla seeds, 5 to 12 weight parts of radix scutellariae, 5 to 12 weight parts of earthworm, 5 to 12 weight parts of batryticated silkworm,3 to 12 weight parts of peach kernel, 3 to 12 weight parts of dark plum fruit, 3 to 12 weight parts of fructus aurantii and 2 to 5 weight parts of liquorice roots as raw materials. The effects of removing heat from the lung to relieve cough, realizing spasmolysis and relieving asthma are achieved; the curative effects on refractory lung heat cough such as cough variant asthma and asthmatic bronchitis are obvious.

The invention provides an application of iodized lecithin in preparing medicines used for treating bronchitis. The iodized lecithin is especially suitable for treating children bronchial asthma and asthmatic bronchitis. Iodized lecithin assists in improving the expansion effect of epinephrine upon trachea smooth muscle, and can directly act upon lung fibroblast cells. With iodized lecithin, in-vivo serum IgE level can be reduced, IL-4 chemokine generating hyperthyroidism can be inhibited, and tissue obstacle of eosinophils can be inhibited. As results of pharmacological and toxicological tests, iodized lecithin is an effective bronchitis-treating medicine with accurate efficacy and low toxic and side effect. Iodized lecithin is especially suitable for treating children bronchial asthma and asthmatic bronchitis.