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Traditional Chinese medicinal composition for tonifying qi, astringing lung, relieving cough and asthma and warming phlegm and retained fluid and preparation method thereof

A technology for relieving cough and relieving asthma and a composition, applied in the field of pharmacy, can solve the problems of unsatisfactory curative effect, low cure rate, easy recurrence and the like

Active Publication Date: 2013-04-03
陕西汉唐制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine has many Chinese patent medicines in the treatment of chronic bronchitis, emphysema, and asthmatic bronchitis, but the curative effect is not ideal
Ministry-issued standard "Prescriptions of Traditional Chinese Medicine" Volume VIII WS 3 - "Compound Haqing Tablet" under item B-1591-93 is a pure traditional Chinese medicine preparation, which has been clinically used for many years and has achieved certain curative effects in the treatment of chronic bronchitis, emphysema, and asthmatic bronchitis; but In clinical application, we found that its curative effect is not ideal enough, and there are disadvantages such as low cure rate, easy recurrence, poor stability; it is sugar-coated tablet, and diabetic patients can take it.

Method used

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  • Traditional Chinese medicinal composition for tonifying qi, astringing lung, relieving cough and asthma and warming phlegm and retained fluid and preparation method thereof
  • Traditional Chinese medicinal composition for tonifying qi, astringing lung, relieving cough and asthma and warming phlegm and retained fluid and preparation method thereof
  • Traditional Chinese medicinal composition for tonifying qi, astringing lung, relieving cough and asthma and warming phlegm and retained fluid and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0115] Formula ratio:

[0116] Dried toad 180g Astragalus 225g Ginkgo 90g Aster 112.5g Bitter almond 112.5g

[0117] Peucedanum 67.5g, aconite 22.5g, taste zi 67.5g, black pepper 22.5g.

[0118] For the above nine flavors, take half the amount of Astragalus membranaceus, crush it into fine powder, and add 50% ethanol to heat and reflux for three times to extract the remaining Astragalus membranaceus, dried toad, ginkgo, aster, bitter almond, peucedanum, aconite, schisandra, and black pepper. Add 10 times the amount for the first time to extract for 2 hours, add 8 times the amount for the second time to extract for 1 hour, and add 8 times the amount for the third time to extract for 1 hour. Combine three extracts, filter, concentrate the filtrate under reduced pressure at 80°C under the condition of -0.08Mpa, and measure a thick paste with a relative density of 1.30 at 60°C, add astragalus fine powder, mix well, make granules, and dry , packed in capsules, and made into 1000 ...

Embodiment 2

[0120] Formula ratio:

[0121] Dried toad 180g Astragalus 225g Ginkgo 90g Aster 112.5g Bitter almond 112.5g

[0122] Peucedanum 67.5g, aconite 22.5g, schisandra 67.5g, black pepper 22.5g.

[0123] For the above nine flavors, take half the amount of Astragalus membranaceus, crush it into fine powder, and add the remaining Astragalus membranaceus, dried toad, ginkgo, aster, bitter almond, peucedanum, aconite, Schisandra chinensis, and black pepper to a total of nine flavors, add 50% ethanol, heat and reflux for three times and add for the first time Extract 10 times the amount for 2 hours, add 8 times the amount for the second extraction for 1 hour, and extract 8 times the amount for the third time for 1 hour. Combine three extracts, filter, concentrate the filtrate under reduced pressure at 80°C under the condition of -0.08Mpa, and measure a thick paste with a relative density of 1.30 at 60°C, add astragalus fine powder, mix well, make granules, and dry , granulate, add an ap...

Embodiment 3

[0125] Formula ratio:

[0126] Dried toad 180g Astragalus 225g Ginkgo 90g Aster 112.5g Bitter almond 112.5g

[0127] Peucedanum 67.5g, aconite 22.5g, schisandra 67.5g, black pepper 22.5g.

[0128] For the above nine flavors, take half the amount of Astragalus membranaceus, crush it into fine powder, and add 50% ethanol to heat and reflux for three times to extract the remaining Astragalus membranaceus, dried toad, ginkgo, aster, bitter almond, peucedanum, aconite, schisandra, and black pepper. Add 10 times the amount for the first time to extract for 2 hours, add 8 times the amount for the second time to extract for 1 hour, and add 8 times the amount for the third time to extract for 1 hour. Combine the three extracts, filter, and concentrate the filtrate under reduced pressure at 80°C under the condition of -0.08Mpa. When it reaches 60°C, a thick paste with a density of 1.30 is measured. Add astragalus fine powder and appropriate amount of dextrin, mix well, and prepare Gra...

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Abstract

The invention relates to a traditional Chinese medicinal composition for tonifying qi, astringing lung, relieving cough and asthma and warming phlegm and retained fluid and a preparation method thereof. The traditional Chinese medicinal composition is prepared from nine traditional Chinese medicines, namely dried toad, astragalus root, ginkgo, aster tataricus, bitter apricot seed, whiteflower hogfennel root, prepared common monkshood daughter root, Chinese magnoliavine fruit and black pepper; the traditional Chinese medicinal composition has effects of tonifying qi, astringing lung, relievingcough and asthma and warming phlegm and retained fluid, is mainly used for lung deficiency cough, asthma with abundance of phlegm, senile chronic trachitis and emphysema, is more suitable for asthmatic bronchitis, and has prevention effect on repeated cold. Compared with the prior art, the traditional Chinese medicinal composition has the advantages that: the process is more reasonable, the effect in a clinical pharmacodynamic test is obviously improved, the bioavailability is high, the medicinal stability is high, and the traditional Chinese medicinal composition does not have any toxic or side effect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for invigorating qi and constricting the lungs, relieving cough and asthma, and warming and transforming phlegm-retention, and a preparation method thereof, belonging to the technical field of pharmacy. technical background [0002] Chronic bronchitis, emphysema, and asthmatic bronchitis are common and frequently-occurring diseases in internal medicine. The main manifestations are cough, wheezing, and expectoration, and the onset occurs in winter and spring, which seriously affects the daily life and work of patients; in severe cases, it can cause chronic emphysema, chronic pulmonary heart disease, and even endanger the lives of patients. At present, Western medicine treats chronic bronchitis, emphysema, and asthmatic bronchitis mainly with anti-inflammatory, bronchial expansion and hormone therapy, which can achieve timely control of the disease and improve clinical symptoms. But it ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/736A61P11/00A61P11/06A61P11/10A61P11/14A61K35/56A61K35/65
Inventor 肖军
Owner 陕西汉唐制药有限公司
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