The invention relates to an ambroxol hydrochloride compound refining method, comprising a step of synthesizing an ambroxol hydrochloride crude product and a step of refining ambroxol hydrochloride, wherein the refining step comprises the following steps: 1) adding water and the ambroxol hydrochloride crude product into a reaction bottle, heating to a temperature of 70-75 DEG C and stirring, and dissolving the crude product, so as to obtain an ambroxol hydrochloride crude product solution; adding active carbon into the ambroxol hydrochloride crude product solution, decolorizing and filtering in a thermal insulating manner, and collecting filtrate; 2) cooling the filtrate to a temperature of 55-60 DEG C, carrying out thermal insulation and stirring; 3) cooling the filtrate to a temperature of 45-48 DEG C, controlling a stirring speed of 15 r/min, adding seed crystal, and crystallizing for 1 hour by controlling a temperature and a stirring speed; 4) cooling to a temperature of 20-25 DEG C and crystallizing for 20 minutes, slowly cooling to a temperature of 10 DEG C for 1.5 hours again after a crystallizing process, and obtaining an ambroxol hydrochloride fine product by leaching and drying. With the adoption of the ambroxol hydrochloride compound refining method provided by the invention, the ambroxol hydrochloride only contains an impurity B in five know impurities; and a content of the impurity B is controlled below 0.005%.