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3 results about "Cilium" patented technology
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A cilium (from Latin, meaning 'eyelash'; the plural is cilia) is an organelle found on eukaryotic cells and are slender protuberances that project from the much larger cell body. There are two types of cilia: motile and non-motile cilia. The non-motile cilia are called primary cilia which typically serve as sensory organelles. There is a third type of cilium that is only transiently present in the early embryo. These are known as nodal cilia and are crucial in the establishment of the left to right body asymmetry.
Respiratory organoids with ciliated epithelial cells attached to the outside and method for producing the same
To provide a method for preparing a respiratory organoid by proliferating and differentiating respiratory epithelial cells.SOLUTION: Unlike conventional respiratory organoids in which epithelial cells existing in an apical region of a respiratory organ are generated on an interior of the organoid, the respiratory organoid of the present disclosure is shown in a form in which ciliated structures, which are epithelial cells, are located in an outer layer of the organoid, secretory cells are present on the interior, and basal stem cells existing at a base of respiratory tissue are also present on the interior of the organoid. It has a form similar to an actual respiratory tissue, and it was observed to exhibit normal functions of the epithelial cells, such as motility of ciliated cells. Therefore, when an organoid is prepared using the preparation method of the present disclosure, a respiratory organoid that can well mimic the actual tissue can be prepared.SELECTED DRAWING: Figure 1
Owner:GIL MEDICAL CENT