134 results about "Osmolyte" patented technology

The present invention relates to methods and compositions for treating diseases ameliorated by increased mucociliary clearance and mucosal hydration by administering an effective amount of a sodium channel blocker as defined herein and an osmolyte to a subject to a subject in need of increased mucociliary clearance and mucosal hydration.

A formulation and method for delivery of bioactive substances when applied to, or within, the skin or other exterior region of a mammal. for example, a patient, includes a vasoactive agent; an osmolyte; and an active ingredient. The formulation is sufficiently hygroscopic so as to create a condition of hypertonicity when absorbed by the skin. When the formulation is applied to the skin, the vasoactive agent can be delivered to the dermis so as to contact the vasculature of a patient.

The invention described herein is directed to method of treating chronic obstructive pulmonary disease, comprising administering an effective amount of an osmolyte by at least one nasal cannula to a subject in need thereof. Also provided is a nasal cannula system for delivering an osmolyte, comprising a nebulizer and tubing having two ends, where the first end of the tubing is connected to the nebulizer and the second end of the tubing is tapered to fit in the nostril of a subject.

The present invention relates to methods and compositions for treating diseases ameliorated by increased mucociliary clearance and mucosal hydration by administering an effective amount of a sodium channel blocker as defined herein and an osmolyte to a subject to a subject in need of increased mucociliary clearance and mucosal hydration.

The invention discloses a method for preparing potato crispy chips through osmotic dehydration and hot air and microwave combined drying, and belongs to the technical field of fruit and vegetable processing. The method mainly comprises the following steps of: cleaning, peeling and slicing potatoes (the thickness of the slices is 4-8mm), blanching for deactivating enzyme (at the temperature of between 90 and 110DEG C), performing osmotic dehydration (penetrating fluid, namely a 40 mass percent sucrose solution is prepared, a mass ratio of the potato crispy chips to the penetrating fluid is 1:(10-12), the soaking temperature is 30-40DEG C, and the soaking time is 30 to 40 minutes), draining water, drying with hot air at the temperature of between 60 and 70DEG C at the air speed of 1-3m/s to obtain a semi-finished product of which the water content is 30 to 40 percent, and performing microwave drying (1-3W/g) finally to obtain the finished product of which the water content is 2 to 5 percent. A new process of assisting in dehydrating through osmotic soaking and performing normal-pressure hot air and vacuum microwave combined drying is adopted, the obtained potato product has nutrient components and color which are maintained well, has crispy texture and avoids defects of high oil content and greasy mouthfeel of a fried food, the production cost is far lower than that of a vacuum freeze-drying product, and the method has the characteristics of short production period, low cost, and good product quality.

The invention belongs to the technical field of microorganisms, and particularly relates to a biocontrol strain, namely trichoderma asperellum T-1, for highly producing composite cellulose degrading enzyme. The trichoderma asperellum T-1 is preserved at the China General Microbiological Culture Collection Center on September 24, 2014; and the preservation number is CGMCC 9722. The invention also provides a waste composting bactericide prepared from the trichoderma asperellum T-1 and an application of the waste composting bactericide in treatment of the organic waste. The trichoderma asperellum T-1 provided by the invention is rapid in growth, high in spore-producing ability, and high pH tolerance; a plurality of cellulose materials can be taken as substrates; and the trichoderma asperellum T-1 is a member of biocontrol bacteria, and can be applied to planting of crops to prevent diseases. By adding the trichoderma asperellum T-1 provided by the invention to the organic waste, the penetrating fluid generated by waste composting can be reduced; the degradation efficiency of the cellulose materials in the waste can be improved; and the quality of the waste composting product is improved.

This invention relates to compositions and methods facilitating availability, uptake and translocation of active ingredients in plants. More specifically, this invention relates to the surprising discovery that the application to the roots, such as administration to the soil surrounding plants, of two or more osmolytes in combination with an active ingredient, either simultaneously or within a short time of each other, results in an induction of translocation of active ingredient from the roots systemically into the plant.

The present invention relates to a method for concentrating law titer fermentation broth, and more particularly to a method for concentrating a fermentation broth using forward osmosis. The method comprises: introducing the fermentation broth and an osmolyte into a feed chamber and a draw chamber, respectively, which are included in a concentration system and are divided from each other by a forward osmosis membrane, and subjecting the introduced fermentation broth to forward osmosis, thereby concentrating the fermentation broth in the feed chamber. The method can maximize the concentration of the low titer fermentation broth while minimizing energy consumption and operating cost, and thus can contribute to the industrialization of new technology.

The present invention discloses a method for purifying polysaccharide iron complex, in particular to a method for desalination and concentration of the crude aqueous polysaccharide iron complex with the ultrafiltration membrane separation technology. Specific methods include the following steps of filtering the crude aqueous polysaccharide iron complex with ultrafiltration membrane components, whereby the pore diameter of ultrafiltration membrane components is between 2 and 50nm and molecular weight cutoff is between 5K and 150KDa; intercepting the polysaccharide iron complex by the ultrafiltration membrane, continuously discharging the sodium chloride and free iron ions in the crude aqueous solution through the osmotic solution to improve the purity and the concentration of polysaccharide iron complex in the ultrafiltration retentate liquid. The method for desalination and concentration of the crude aqueous polysaccharide iron complex with the ultrafiltration membrane provided by the invention has the following advantages of 1. simple operation process, safety and energy saving, mild condition and easy for continuous production; 2. reducing the salt concentration in the aqueous polysaccharide iron complex, and increasing the concentration of polysaccharide iron with recovery rate of more than 95%.

The invention discloses a vacuum blood collection tube, particularly a vacuum blood collection tube for storing and transporting a circulating nucleic acid sample. The vacuum blood collection tube comprises an original tube, a rubber plug and a protective cap, wherein the original tube is vacuumized; the rubber plug seals the original tube; a composite additive is arranged inside the original tube; the composite additive is obtained by mixing a chelating agent, an enzyme inhibitor, an osmotic agent, an antioxidant, an apoptosis inhibitor, a cell membrane stabilizer and a buffer solution. The invention can enable a collected sample to keep a whole-blood initial state under a room-temperature condition for 7-14 days without deterioration, and also can ensure that circulating nucleic acids inplasma or serum of whole blood are not degraded and whole blood cells are free of apoptosis and rupture, so that the circulating nucleic acids existing in the plasma or the serum are prevented from being contaminated by genomic nucleic acids, and adverse effects of a cross-linking action of a formaldehyde slow release agent-based preservation solution on subsequent experiments are avoided.

A crosslinked polymeric polyvinyl sulfate membrane or crosslinked copolymer polyvinyl sulfate and polyvinyl alcohol membrane, suitable for use in an acid environment, and its use for recovering acid from a feed mixture comprising acid, hydrocarbons and water, the method comprising: processing said mixture using a first polymeric membrane to form a first retentate containing a substantially greater concentration of hydrocarbons than said feed mixture and a first permeate containing a substantially greater concentration of acid and water than said mixture, said first polymeric membrane being selectively permeable to the acid and water over the hydrocarbons found in the mixture, and recovering the first permeate; said first permeate can be processed further using a second water reduction mean to form a first stream containing a substantially greater concentration of acid than said first permeate and a second stream containing a substantially greater concentration of water than said first permeate, said water reduction step may be a second polymeric membrane being selectively permeable to the water over the acid in said first permeate; and recovering said second stream or retentate.

The invention relates to an absorbent article for application to human or animal skin surfaces in the region of wounds, consisting of an outer covering (2) which is permeable for liquid substances, and of an inner layer (1) which is surrounded by the covering (2) and which consists essentially of a mixture of an amount of strongly osmotically active substances with an amount of osmotically comparatively weak or osmotically inactive substances, such as cellulose. The inner layer (1) is filled with osmotically active substances in such a way that it is possible to exert on a wound, with the wound fluids contained therein, an osmotic pressure via which the wound fluid can be removed from the organism to be treated, and thus it is possible to assist both in the surfaced wound region and in the depth of the tissue a normal interstitial hydration of tissue by directing endogenous fluids in their direction of flow to the patient's skin surface into the absorbent article, and keeping them there.

The invention relates to a dynamic evaluation method of the scale inhibition performance of a reverse osmosis scale inhibitor, which comprises the following steps: (1) establishing a reverse osmosis operating system, mounting a concentrated water adjusting valve on a reverse osmosis concentrated solution pipe, and adjusting a reverse osmosis system to operate at a certain recovery rate by the concentrated water adjusting valve; (2) adding raw water and a certain dosage of scale inhibitor for test into the system, recording operating pressure and solution temperature of a reverse osmosis membrane, flow rate, or weight, or volume of penetrating solution and the concentrated solution, and concentration of scaling ions in the raw water and the concentrated solution in the operating progress; and (3) calculating concentration ratio according to the flow rate, or the weight, or the volume of the penetrating solution and the concentrated solution, calculating concentration ratio of the scaling ions in the concentrated solution and the raw water, and then evaluating performance of the scale inhibitor by an extreme value error method. The method disclosed by the invention is rapid, accurate, simple in test condition, and easy in operation.

The invention relates to the technical field of soil remediation, in particular to a remediation agent and remediation method for heavy metal contaminated soil. The remediation agent for the heavy metal contaminated soil comprises 2-16 parts of humic acid, 5-10 parts of succinic acid, 5-20 parts of sawdust, 2-10 parts of bentonite, 10-20 parts of sodium polyacrylate, 5-10 parts of honeycomb briquette ash, 5-20 parts of seaweed residues, 2-10 parts of zeolite, 5-10 parts of nano hydrogel, 10-30 parts of charcoal, 10-20 parts of Fe-Mn binary oxide, 5-10 parts of sodium pyrophosphate and 2-10 parts of microorganism mixed bacteria. The remediation agent is good in repairing effect and low in cost. The remediation method for remediating the heavy metal contaminated soil through the remediationagent is simple, heavy metal in the soil can be efficiently solidified, and the water quality grade of the soil penetrating fluid is improved.

The present invention relates to dissolved silicate compositions in which the dissolved silicate is stabilized by at least two selected osmolytes and is therefore bioavailable. The composition and its dilutions are stable over a long period of time and are used in a wide field of applications for the benefit of living organisms such as plants, animals and humans.

The invention relates to engineering flaw detection which is related with micro-fractures on the surface of a metal workpiece, in particular to reaction-type coloring flaw detection penetrating fluid. The invention also relates to an engineering flaw detection method, in particular to a nondestructive flaw detection method which is simple and is simple and convenient to operate. The invention aims to provide a colorless transparent penetrating agent which is really colorless, transparent, pollution-free and natural and does not need to react for the second time. In order to achieve the goal of the invention, the invention is realized in such a mode as follow: the colorless transparent penetrating agent is characterized by consisting of polyalcohol, surface active agent and water, wherein the polyalcohol accounts for 30-60 percent, the surface active agent accounts for 8-15 percent, and the balance is a dissolving agent. By adopting the scheme, the complicated formula in the past is not needed. A detection effect can be achieved only by mixing three ingredients which are the most natural and simplest.

The invention discloses a nanometer combined solution capable of generating negative oxygen ions. The nanometer combined solution capable of generating negative oxygen ions comprises a penetrating fluid, a negative ion liquid, and a sealing liquid which are prepared independently, wherein the penetrating fluid is prepared from, by mass 10 to 50% of nanometer silica, 2 to 10% of a suspending agent,and the balance water, the negative ion liquid is prepared from, by mass, 5 to 50% of tourmalinite, 0.1 to 1% of sodium carboxymethylcellulose, 0.1 to 3% of an activator, and the balance water; and the sealing liquid is prepared from, by mass, 1 to 30% of organic silicone oil, and the balance water. Compared with conventional products, the nanometer combined solution possesses following advantages: the penetrating fluid of relatively large particles are capable of penetrating relatively pores on ceramic surface, in dispersion of the negative ion liquid, the penetrating liquid can be taken asa carrier of the negative ion liquid, the contact area of tourmalinite surface with the air is enlarged effectively, and more negative oxygen ions are generated.

The invention relates to the technical field of sewage treatment and particularly relates to a garbage leachate treatment process and device. The process comprises the following steps of introducing garbage leachate into a filter for filtering, and removing particulate matters from the garbage leachate, so as to obtain a filtrate; introducing the filtrate into a reverse osmosis membrane device for treatment, so as to obtain produced water and high-concentration water; adding a proper amount of denitrification agent into the produced water, so as to obtain clean water reaching the emission standard; introducing the high-concentration water into a struvite reactor, reacting for 1-30 minutes, so as to obtain a mixture of precipitate and medium-concentration water, and filtering, so as to obtain a fertilizer and the medium-concentration water; carrying out coagulation treatment on the medium-concentration water by a coagulation method, so as to obtain a mixture of flocculate and low-concentration water, and filtering, so as to obtain sludge and the low-concentration water; introducing the low-concentration water into biochemical facilities for treatment, thereby obtaining clean water reaching the emission standard. According to the process and the device, the operation is simple, convenient and efficient, the structure is simple, outlet water is discharged in a standard reaching manner or reused, and high-concentration ammonia nitrogen is recovered as the fertilizer, so that the waste is changed into the valuable, and the economic benefit is high.