The invention relates to a biological
metabolism regulator based on radix paeoniae alba
polysaccharide iron and a preparation method and application thereof.The preparation method comprises the following steps that radix paeoniae alba
polysaccharide and
trisodium citrate are completely dissolved in pure water, a
ferric trichloride solution is slowly added under magnetic stirring, a
sodium hydroxide solution is dropwise added at the same time, after the reaction is completed,
centrifugation is conducted, and supernatant is obtained; and adding absolute ethyl
alcohol to separate out the radix paeoniae alba polyferose. Centrifuging to take precipitate, repeating for three times, and dissolving with pure water; and dialyzing the solution with deionized water, then adding absolute ethyl
alcohol for
precipitation and
centrifugation, repeating for three times, and freeze-
drying to obtain the radix paeoniae alba polyferose product. The product can stably reach the intestinal tract in a targeted mode, remove ROS in the intestinal tract and regulate glycometabolism of macrophages, so that polarization
typing of the macrophages is changed, the anti-inflammatory effect is achieved, and new possibility is provided for treatment of the
inflammatory bowel disease. Animal experiments prove that the radix paeoniae alba polyferose enteric
capsule has a better and more stable comprehensive
treatment effect on mice with
inflammatory bowel diseases than a radix paeoniae alba polyferose solution.