3 results about "Polysaccharide iron" patented technology

A Panax notoginseng polysaccharide iron nanoparticle preparation, its preparation method, and its application are disclosed. This invention can effectively prepare Panax notoginseng polysaccharide iron nanoparticles, solving the application problem in the preparation of drugs for treating iron deficiency anemia, inflammatory bowel disease-related anemia, iron deficiency anemia-related colitis, inflammatory anemia, or inflammatory bowel disease. The specific steps are as follows: The crude Panax notoginseng polysaccharide solution is purified using conventional purification methods to obtain purified Panax notoginseng polysaccharide. This purified polysaccharide is dissolved in ultrapure water, and an iron source is added under inert gas protection. After co-precipitation and chemical reduction reactions, the pH value is adjusted, and iron nanoparticles are loaded onto the Panax notoginseng polysaccharide to obtain Panax notoginseng polysaccharide-coated iron nanoparticles. The preparation method of this invention is simple, uses abundant raw materials, and has low production costs. It represents a major innovation in drugs for treating iron deficiency anemia and inflammatory bowel disease-related iron deficiency anemia, and has practical application value.

This invention discloses a method for preparing highly stable soybean protein hydrolysate-polysaccharide-iron composite nanoparticles, aiming to solve the problems of high cost, harsh process conditions, and poor stability of iron fortifiers in food applications in existing technologies. The preparation method includes: dispersing soybean protein in water, adding protease for enzymatic hydrolysis for 0-12 h, inactivating the enzyme, mixing with a polysaccharide dispersion and adjusting to a specific pH, stabilizing, adding ferrous sulfate solution, allowing the reaction to proceed fully, adjusting the pH back to near neutral, and then centrifuging to collect the supernatant to obtain soybean protein hydrolysate-polysaccharide-iron composite nanoparticles with a particle size of 80-300 nm. The nanoparticles prepared in this application exhibit good binding rate, dispersibility, application stability, and bioavailability, overcoming the technical bottleneck of traditional iron fortifiers that struggle to balance bioavailability and food compatibility. They have certain application potential and value in functional iron-fortified foods and biomedicine.

The present invention falls within the technical field of iron supplement preparation, and relates more particularly to a process for preparing and applying a supplement based on a polysaccharide-iron complex derived from Auricularia auricula-judae, intended to supplement iron, improve iron deficiency anemia and strengthen immunity, comprising the following steps: preparation of raw materials, selection of iron-rich Auricularia auricula-judae as raw material; culture and optimization, engineering modification of fermented and cultured Auricularia auricula-judae; screening and selection of Auricularia auricula-judae strains with a high iron content;The beneficial effects are as follows: by constructing gene expression vectors, transforming fungal cells, and screening and identifying transformants with high synthetic capacity, the level of expression of genes related to the generation and conversion of the iron element is increased, allowing the cultivation of Auricularia auricula-judae varieties containing higher levels of iron, in order to improve the yield and production efficiency of the polysaccharide-iron complex.