1934 results about "Trisodium citrate" patented technology

Improved flow cytometer system particularly adapted to use for sex-selected sperm sorting include enhanced sheath fluid and other strategies which minimize stress on the sperm cells, including a 2.9 percent sodium citrate sheath solution for bovine species and a hepes bovine gamete media for equine species. Improved collection systems and techniques for the process are described so that commercial applications of sperms samples as well as the resulting animals may be achieved.

A process for producing a fine silver particle colloidal dispersion which can simply form conductive silver layers and antimicrobial coatings by screen printing or the like. The process is characterized by having a reaction step of allowing an aqueous silver nitrate solution to react with a mixed solution of an aqueous iron(II) sulfate solution and an aqueous sodium citrate solution to form an agglomerate of fine silver particles, a filtration step of filtering the resultant agglomerate of fine silver particles to obtain a cake of the agglomerate of fine silver particles, a dispersion step of adding pure water to the cake to obtain a first fine silver particle colloidal dispersion of a water system in which dispersion the fine silver particles have been dispersed in the pure water, and a concentration and washing step of concentrating and washing the first fine silver particle colloidal dispersion of a water system.

Implanted catheters are locked with a solution comprising a lower alcohol, typically ethanol, propanol, or butanol, most preferably isopropanol, and an additive, the additive comprising an anti-microbial, typically taurolidine or triclosan, or an anti-coagulant, typically riboflavin, sodium citrate, ethylene diamine tetraacetic acid, or citric acid. The use of an alcohol and additive solution can effectively reduce fouling of the catheter, particularly clotting and thrombus in intravascular catheters, as well as reduce the risk of infection. The risk of infection can be further reduced by employing a catheter body which is sufficiently porous to permit the anti-microbial solution of a lower alcohol and another anti-microbial or anti-coagulant compound to penetrate into the catheter body and preferably through the catheter into tissue surrounding the implanted catheter.

The invention relates to a preparation method of a triangular silver nanosheet, which comprises the following steps: firstly, mixing three types of reagents of oxyacid silver, trisodium citrate (Na3C6H5O7.2H2O) and polyvinyl pyrrolidone (PVP) according to a certain molar ratio; stirring for 4-10min at the temperature of 0 DEG C-30 DEG C; adding a proper amount of sodium borohydride (NaBH4) reagent into the mixed system; and then, adding a proper amount of hydrogen peroxide the mass fraction of which is 10%-30% to finally obtain the triangular silver nanosheet the size of which is 50nm-120nm. The method for preparing the triangular silver nanosheet has simple operation and high success ratio and can be carried out at normal temperature.

The invention discloses a preparation method for composite nano particcle of superparamagnetic ferric oxide. Wherein, adding ammonia and sodium citrate synchronously and speed controlled to make ions of Fe3+ and Fe2+ coprecipitate and form Fe3O4 nano particle with water-phase dispersion surface adsorbed by citric acid radical that can be substituted by multi chemical functional group on basic condition as crystal seed for sodium citrate-goden chloric acid reduction reaction and form SPION nano particle.

The present invention provides a gel beverage composition for comprehensive nutritional supplementation, having balanced nutrients, refreshing taste, a low pH, a soft gel form suitable for drinking / eating and the ability to retain its gel form for a long period of time. The composition is a gel which has a pH ranging from 3-4 and contains 5-20% by weight of saccharide, 0.1-5% by weight of fat, 2.5-6% by weight of protein material which does not coagulate at pH 3-4, 0.2-3% by weight of citric acid, 0.2-1.5% by weight of at least one acid component selected from the group consisting of ascorbic acid, tartaric acid, succinic acid, malic acid, gluconic acid, phosphoric acid, phytic acid, lactic acid and trisodium citrate, 0.01-0.5% by weight of an emulsifying agent, 0.1-1% by weight of agar and 65-90% by weight of water.

The blood collection, processing and transfer by separation of discrete components containing additional citrate (at least about trisodium citrate 9% w / v) in one or other of collection or processing bag provides for enhanced yield and purity of cryoprecipitate. Inhibiting the activation or denaturation of blood components including blood cells and plasma proteins and with the removal of the activated and denatured components thereby improving safety and efficacy of end products. The inventive process is particularly suited to an improved extraction process to yield concentrated clotting factors from single donors or limited pools without use of chromatography. Following extraction the remaining cryoprecipitate can advantageously be formed into a fibrin fabric used in surgeries and in the treatment of wounds

The blood collection, processing and transfer by separation of discrete components containing additional citrate (at least about trisodium citrate 9% w / v) in one or other of collection or processing bag provides for enhanced yield and purity of cryoprecipitate. Inhibiting the activation or denaturation of blood components including blood cells and plasma proteins and with the removal of the activated and denatured components thereby improving safety and efficacy of end products. The inventive process is particularly suited to an improved extraction process to yield concentrated clotting factors from single donors or limited pools without use of chromatography. Following extraction the remaining cryoprecipitate can advantageously be formed into a fibrin fabric used in surgeries and in the treatment of wounds.

The invention discloses a frozen bovine semen diluent, and the consumption amounts of all the raw materials in 100ml of the diluent are: 0.8 to 1.2g of fructose, 1.4 to 1.6g of sodium citrate, 2.3 to 2.6g of TRIS, 7.5 to 9.5g of low-density lipoprotein, 5 to 8ml of glycerol, 0.085 to 0.12 million IU of penicillin and the rest is distilled water. The preparation method is that: the fructose, the sodium citrate and the TRIS are dissolved in the distilled water to be prepared into a base liquid; penicillin G sodium and the low-density lipoprotein are added in the base liquid to prepare a I liquid; the glycerol is added in the I liquid to prepare a II liquid; then the pH value is adjusted to 6 to 7.5, then a filtration and a sterilization are carried out, and the liquid is cooled until reaching the room temperature and then arranged in a refrigerator of 2 - 5 DEG C for standby. The frozen bovine semen diluent of the invention has good and reliable effect, which can provide high-quality and excellent straw frozen semen for bovine artificial insemination and have very broad market application prospect.

The invention relates to a carbon dioxide electrochemical reduction catalyst as well as a preparation method and an application thereof. The carbon dioxide electrochemical reduction catalyst comprises tin dioxide nanoflower, wherein the tin dioxide nanoflower is synthesized through hydrothermal reaction and comprises the synthesis raw materials including 0.1-0.5M of tin dioxide, 1-5M of trisodium citrate mixed solution and 0.1-0.5M of sodium hydroxide. The carbon dioxide electrochemical reduction catalyst is applied to a carbon dioxide electrochemical reduction catalyst gas diffusion electrode. The carbon dioxide electrochemical reduction catalyst has the advantages that the specific surface area of the catalyst is enlarged, the electrochemical reduction catalytic activity of the catalyst for carbon dioxide reduction is improved, the hydrogen evolution reaction is effectively inhibited, and the selectivity of formic acid in a product is improved.

The invention discloses a method for preparing cauliflower nano gold-silver alloy with a surface-enhanced Raman scattering activity, which comprises: mixing 0.001mol / L solution of silver nitrate and 0.001mol / L solution of sodium phytate in a volume ratio of 30:1; heating the mixed solution till the mixed solution boils and keeping the temperature between 90 and 100 DEG C; adding 1 percent solution of trisodium citrate in an amount which is one fiftieth of the volume of the solution of silver nitrate to perform an reaction at 90 to 100 DEG C for 3 hours to prepare nano silver cluster dispersion stabilized by phytic acid; and transferring 12 to 17 milliliters of dispersion into a 25 milliliter beaker, heating the solution to 45 to 65 DEG C with stirring, slowing dripping 1.5 to 2.4 millimeters of 0.01 mol / L solution of chloroauric acid and stirring the mixed solution for 25 to 35 minutes to obtain a sample. The obtained cauliflower nano gold-silver alloy nanoparticles can keep stable for more than 6 months and has high signal repeatability and a surface-enhanced Raman effect. The preparation method is simple and low in cost.

The invention discloses a method for preparing an antibacterial composite material with nano-silver particles evenly dispersed in a polymeric matrix, which belongs to technique for preparing antibacterial nano composite materials and comprises the following steps: preparing styrene / methyl methacrylate hybrid monomers, a sodium dodecyl sulfate hybrid monomer solution, a silver nitrate aqueous solution and a trisodium citrate aqueous solution; mixing the silver nitrate aqueous solution and the trisodium citrate aqueous solution with the sodium dodecyl sulfate hybrid monomer solution according to a volume ratio to obtain a micro-emulsion containing silver nitrate and a micro-emulsion containing trisodium citrate; stirring and mixing the two micro-emulsions to obtain a stable micro-emulsion having hybrid monomers of continuous phases and containing the nano-silver particles; and then dispersing the emulsions in distilled water to prepare a common emulsion, introducing nitrogen for deoxidization, adding an initiator to perform emulsion polymerization reaction, using sodium chloride to perform emulsion-breaking and separation on the product, fully washing the product with deionized water, and soaking the product in ethanol, and drying the product to constant weight so as to obtain the antimicrobial nano-silver / poly(styrene-methyl methacrylate) composite material. The method has simple preparation processes and can make the nano-silver particles evenly dispersed in the polymer matrix, and the prepared composite material has broad-spectrum bactericidal property, and has high fatality rate to Escherichia coli, bacillus subtilis, staphylococcus aureus and pseudomonas aeruginosa in 24 hours.

The invention discloses a water-base oil dirt cleaning agent and a preparation method thereof, wherein the water-base oil dirt cleaning agent has the characteristics of being strong in cleaning capability, excellent in biodegradation, low in preparation cost, environmentally-friendly, efficient and the like, and is specifically suitable for cleaning heavy oil dirt on the road pavement. The water-base oil dirt cleaning agent consists of the following components in weight proportion: 2-7% of anionic surfactant, 2-8% of nonionic surfactant, 1.5-3% of triethanolamine, 1-3% of trisodium citrate and the balance of water, wherein the anionic surfactant is preferably selected from two or three of alpha-vinyl sodium sulfonate (AOS), sodium dodecyl benzene sulfonate (LAS) and sulfonate of fatty acid methyl ester ethoxylate (FMES); and the nonionic surfactant is preferably selected from one or two of fatty alcohol-polyoxyethylene ether (AEO-9) and cocamidopropyl betaine (CAB).

The invention relates to a blocking remover of a gas well shaft. The blocking remover comprises, by weight, 5-25% of an alcohol ether compound, 0.5-10% of a dispersant, 1-10% of a cleaning agent, and 0.5-5% of chelating agent, with the balance being a nitrogen-containing polar solvent, wherein the nitrogen-containing polar solvent is one selected from N,N dimethyl formamide, N,N dimethyl acetamide, and N-methyl pyrrolidone, the alcohol ether compound is one selected from glycol-ether, glycol-propyl ether, glycol-butyl ether, and diglycol-ether, the disperant whose micelle particle size is from 20nm to 100nm is a middle-phase microemulsion-type dispersant mixed by kerosene, water, a surfactant and a cosurfactant, the cleaning agent is one selected from allene diamine, acetonitrile and pentylamine, and the chelating agent is one selected from sodium citrate and EDTA. The blocking remover has the advantages that corrosivity is weak, that the speed of dissolving blockage is fast, that the product performance is stable in high temperatures, and that the blocking remover can reduce damages caused by water locking and fouling in areas close to gas wells, and can recover the permeability of storing layers.

The invention relates to a selenium-rich chitosan nutritional microbial fertilizer. The selenium-rich chitosan nutritional microbial fertilizer is prepared from the following raw materials: sodium selenite, chitosan hydrolysate, compound trace elements, monopotassium phosphate, urea, peptone, yeast powder, NaCl, NaOH, NaNO3, NaCl, NH4Cl, K2HPO4, a beef extract, glucose, starch, calcium carbonate, amino acid, potassium nitrate, ferrous sulfate, magnesium sulfate, trisodium citrate, biochemical enzymes and a mixed bacterium liquid. Due to addition of the chitosan, the viable count of a microbial agent can be kept; the efficacy of the chitosan for keeping the viable count is put into an effective play; due to addition of the chitosan, the amount of bacteria of the microbial agent can reach 20,000,000,000 / mL; due to addition of the chitosan to a bacterial manure, the yield of commercial crops can also be increased by 10%-15%; and the nutritional microbial fertilizer has the efficacies of keeping moisture and slowly releasing fertilizer efficiency.

The invention belongs to the technical field of nano-silver antibacterial materials and discloses an aminated polyethylene glycol functional graphene oxide loaded nano-silver antibacterial material, a preparation method of the antibacterial material and an application of the antibacterial material in the fields of bacteriostasis and sterilization. The method comprises the following steps: adding aminated polyethylene glycol into an aqueous solution of graphene oxide, adding 1-ethyl-(3-dimethylaminopropyl) carbonyldiimine hydrochloride and N-hydroxy succinimide, regulating the pH value, stirring, and reacting, thereby obtaining the aminated polyethylene glycol modified graphene oxide; preparing the aqueous solution of the graphene oxide, adding silver nitrate, heating until the solution is boiled after dissolving, adding sodium citrate or NaBH4 aqueous solution, reacting, and cooling, thereby obtaining the aminated polyethylene glycol functional graphene oxide loaded nano-silver antibacterial material. The antibacterial material prepared by the invention has good water solubility and stability, the loading efficiency and antibacterial activity are obviously improved, and the antibacterial material has obvious antibacterial activity and can be widely applied to the fields of bacteriostasis and sterilization.

The subject of the invention is superparamagnetic nanoparticle probes based on iron oxides, to advantage magnetite or maghemite, with modified surface, coated with mono-, di- or polysaccharides from the group including D-arabinose, D-glucose, D-galactose, D-mannose, lactose, maltose, dextrans and dextrins, or with amino acids or poly(amino acid)s from the group including alanine, glycine, glutamine, asparagine, histidine, arginine, L-lysine, aspartic and glutamic acid or with synthetic polymers based on (meth)acrylic acid and their derivatives selected from the group containing poly(N,N-dimethylacrylamide), poly(N,N-dimethylmethacrylamide), poly(N,N-diethylacrylamide), poly(N,N-diethylmethacrylamide), poly(N-isopropylacrylamide), poly(N-isopropylmethacrylamide), which form a colloid consisting of particles with narrow distribution with polydispersity index smaller than 1.3, the average size of which amounts to 0.5-30 nm, to advantage 1-10 nm, the iron content is 70-99.9 wt. %, to advantage 90 wt. %, the modification agent content 0.1-30 wt. %, to advantage 10 wt. %.The particles of size smaller than 2 nm with polydispersity index smaller than 1.1 can be obtained by a modified method of preparation.Superparamagnetic nanoparticle probes according to the invention are prepared by pre-precipitation of colloidal Fe(OH)3 by the treatment of aqueous 0.1-0.2M solution of Fe(III) salt, to advantage FeCl3, with less than an equimolar amount of NH4OH, at 21° C., under sonication, to which a solution of a Fe(II) salt, to advantage FeCl2, is added in the mole ratio Fe(III) / Fe(II)=2 under sonication and the mixture is poured into five- to tenfold, to advantage eightfold, molar excess of 0.5M NH4OH. The mixture is left aging for 0-30 min, to advantage 15 min, and then the precipitate is repeatedly, to advantage 7-10 times, magnetically separated and washed with deionized water. Then 1-3 fold amount, to advantage 1.5 fold amount, relative to the amount of magnetite, of 0.1 M aqueous solution of sodium citrate is added and then, dropwise, 1-3 fold amount, to advantage 1.5 fold amount, relative to the amount of magnetite, of 0.7 M aqueous solution of sodium hypochlorite. The precipitate is repeatedly, to advantage 7-10 times, washed with deionized water under the formation of colloidal maghemite to which, after dilution, is added dropwise, to advantage under 5-min sonication, an aqueous solution of a modification agent, in the weight ratio modification agent / iron oxide=0.1-10, to advantage 0.2 for amino acids and poly(amino acid)s and 5 for saccharides.The particles smaller than 2 nm with polydispersity index smaller than 1.1 are prepared by mixing at 21° C. 1 volume part of 10-60 wt. %, to advantage 50 wt. %, of an aqueous solution of a saccharide, disaccharide or polysaccharide, such as D-arabinose, D-glucose, D-galactose, D-mannose, lactose, maltose, dextran and dextrins, and 1 volume part of aqueous solution of a Fe(II) and Fe(III) salt, to advantage FeCl2 and FeCl3, where the molar ratio Fe(III) / Fe(II)=2. A 5-15%, to advantage 7.5%, solution of NH4OH is added until pH 12 is attained and the mixture is heated at 60° C. for 15 min. The mixture is then sonicated at 350 W for 5 min and then washed for 24 h by dialysis in water using a membrane with molecular weight cut-off 14,000 until pH 7 is reached. The volume of solution is reduced by evaporation so that the final dry matter content is 50-100 mg / ml, to advantage 80 mg per 1 ml.Superparamagnetic nanoparticle probes according to the invention can be used for labelling cells used in magnetic resonance imaging for monitoring their movement, localization, survival and differentiation especially in detection of pathologies with cell dysfunction and of tissue regeneration and also for labelling and monitoring cells administered for cell therapy purposes, in particular embryonal stem cells, fetal stem cells, stem cells of an adult human including bone marrow stem cells, olfactory glial cells, fat tissue cells, in the recipient organism by magnetic resonance.The preparation of labelled cells proceeds by adding to the complete culture medium 5-20 μl, to advantage 10 μl, of a colloid containing 0.05-45 mg iron oxide per ml, to advantage 1-5 mg iron oxide per ml of the medium, and culturing the cells for a period of 1-7 days, to advantage for 1-3 days, at 37° C. and 5% of CO2.

The invention especially relates to a Raman probe using a gold nanosol as a substrate for detection of mercury ions and a preparation method thereof, which belongs to the technical field of Raman spectrum detection. The preparation method comprises the following steps: adding secondary deionized water into a nano-silver dispersion liquid with phytic acid micelle as a protective agent, carrying out stirring, heating to a temperature of 40 to 60 DEG C, adding a perchloroauric acid solution drop by drop, carrying out stirring for 10 to 20 min, then adding trisodium citrate drop by drop and carrying out stirring for 10 to 20 min and cooling so as to prepare the gold nanosol; and adding crystal violet into the prepared gold nanosol and carrying out uniform mixing. The preparation method for the Raman probe is simple and convenient and needs short preparation time. A gold nanoparticle in the Raman probe has good stability; and the Raman probe has the advantages of capacity of rapid detection of mercury, high sensitivity, good selectivity and a mercury ion detection limit of 0.5*10<-12> mol / L.

Implanted catheters are locked with a solution comprising a lower alcohol, typically ethanol, propanol, or butanol, in a range from 1% to 99% by volume, and an additive in a range from 1% to 99% by volume, the additive comprising an anti-microbial, typically taurolidine or triclosan, or an anti-coagulant, typically riboflavin, sodium citrate, ethylene diamine tetraacetic acid, or citric acid. The use of an alcohol and additive solution can effectively reduce fouling of the catheter, particularly clotting and thrombus in intravascular catheters, as well as eradicate existing infections and / or reduce the risk of potential infections. Existing infections and / or potential infections can be further reduced by employing a catheter body which permits an anti-microbial solution to penetrate into the catheter body and preferably through the catheter into tissue surrounding the implanted catheter.

The invention relates to a preparation method of a NiCo2S4-coated porous carbon skeleton for a positive electrode material of a lithium-sulphur battery. The preparation method comprises the followingsteps: preparing a nitrogen-doped porous carbon skeleton; preparing a C@NiCo-LDH composite material: adding the nitrogen-doped porous carbon skeleton prepared in the last step, cobalt nitrate hexahydrate, nickel nitrate hexahydrate, urotropin and sodium citrate according to the molar ratio of (10-15): (60-120): (30-60):30:10 into deionized water, after stirring uniformly, carrying out oil bathingat a temperature of 70-90 DEG C, carrying out condensation and returning for 3-6 hours, centrifuging reaction products using the deionized water and alcohol, drying to obtain the NiCo-LDH-coated porous composite material which is marked as C@NiCo-LDH; preparing the C@NiCo2S4 composite material; and loading sulfur on the C@NiCo2S4 composite material.

The invention generally relates to formulations having particles comprising phospholipids, bioactive agent and excipients and the pulmonary delivery thereof. Dry powder inhaled insulin formulations are disclosed. Improved formulations comprising DPPC, insulin and sodium citrate which are useful in the treatment of diabetes are disclosed. Also, the invention relates to a method of for the pulmonary delivery of a bioactive agent comprising administering to the respiratory tract of a patient in need of treatment, or diagnosis an effective amount of particles comprising a bioactive agent or any combination thereof in association, wherein release of the agent from the administered particles occurs in a rapid fashion.

The invention relates to a preparation method of polystyrene / gold composite microspheres, which comprises the following steps: modifying polystyrene microspheres with a silane coupling agent, mixing with a chloroauric acid solution, and heating to carry out ionic selfassembly, wherein gold ions are fixed to the surface of the polystyrene microspheres through gold-nitrogen bonds; and after the solution is boiling, adding trisodium citrate to reduce the gold ions adsorbed onto the amino group in situ, thereby generating the core-shell structure in which a gold nanoparticle is coated on each polystyrene microsphere. The size of the gold particles and the coverage percentage of the gold particles on the polystyrene microspheres are controllable to some extent.

The invention discloses a method for preparing functional gold nanoparticles with high stability, which belongs to the technical field of material chemistry. The method comprises the following steps of: the DNA-assisted synthesis of the gold nanoparticles, the salt tolerance experiment of the synthesized gold nanoparticles, the representation of the synthesized gold nanoparticles and the biometric identification of the DNA on the surfaces of the gold nanoparticles. In the method, four kinds of DNAs with three different lengths are utilized and a chloroauric acid is reduced by trisodium citrate to realize the assisted synthesis of the gold nanoparticles; the DNAs of 12 basic groups are obtained by performing representation with an electron microscope to assist in synthesizing the uniform spherical gold nanoparticles, and particularly, the gold nanoparticles obtained by the 12-G-assisted synthesis have regular shapes and a uniform particle size; the salt-tolerant effect of the gold nanoparticles obtained by the salt tolerance experiment of the synthesized gold nanoparticles can be bettered by 20 times; and the gold nanoparticles can enhance the fluorescence of FAM-DNA, and are expected to be well applied to the preparation of nanometer medicaments and nanodevices.

The invention relates to an oxiracetam injection solution which comprises 1 weight portion of oxiracetam, 1.5 to 5.5 weight portions of glucose and 50 to 100 weight portions of injection water, wherein, the pH value of the injection solution is 3.8 to 4.5. The invention also provides a preparation method of the oxiracetam injection solution which comprises the steps as follows: a) the bulk drug oxiracetam and the glucose or sodium chloride are solved in the injection water under the temperature of 40 DEG C to 70 DEG C to obtain dissolved solution; b) the dissolved solution is cooled to the room temperature, active carbon is added for decolorizing, the active carbon is removed by filtering, proper quantity of water is complemented, and citric acid and sodium citrate are added to adjust the pH value to 3.8 to 4.5 to obtain the dissolved solution with adjusted pH value; c) an intermediate product after encapsulation is sterilized; and d) the product after the sterilization is packed. The oxiracetam injection solution manufactured by the prescription and the preparation method of the invention has good storage stability.

The invention discloses a selenium-enriched microorganism preparation prepared from fermentation of a mixed bacterium liquid. The selenium-enriched microorganism preparation consists of the following raw materials: sodium selenite, complex trace elements, monopotassium phosphate, urine, peptone powder, NaCl, NaOH, NaNO3, NaCl, NH4Cl, K2HPO4, a beef extract, glucose, starch, calcium carbonate, amino acid, potassium nitride, ferrous sulfate, magnesium sulfate, trisodium citrate, a biochemical enzyme and a mixed bacterium liquid; and the mixed bacterium liquid is a mixed liquid of the bacterium liquid of bacillus amyloliquefaciens, the bacterium liquid of bacillus subtilis, the bacterium liquid of bacillus licheniformis, the bacterium liquid of bacillus thuringiensis and the bacterium liquid of bacillus mucilaginosus. The mixed bacterium liquid applicable to the selenium-enriched microorganism preparation disclosed by the invention is conducive to microorganisms in soil, and can be used for increasing the quantity of the microorganisms in the soil and enhancing the activity of the microorganisms in the soil. Due to vital activity and metabolite, the strain is an agricultural product which can cause special fertilizer effect, growth regulating effect, effect of prevention and control of plant diseases and pests, soil bioremediation and the like to crops.

The invention provides a preparation method of oxidized grapheme / silver particle nanometer compound and application thereof, and an oxidized grapheme solution is prepared by an improved Hummers method, and silver nitrate solid powder is added and boiled, and trisodium citrate is added as reducing agent and stabilizing agent, and the solution is boiled for 1 hour continuously and washed out for 3 times by a ultrafiltration pipe. Compared with the prior art, the preparation method provided by the invention is simple and fast, and the prepared nanometer compound has the advantages of stable structure, good water-solubility and good antibiosis activity, and the product can be used as antibiosis material with high efficiency and safety.

The invention discloses a reticulate nanopore zinc-oxide micron hollow sphere and a preparation method thereof. The hollow sphere of the invention comprises the following materials: the surface of the zinc-oxide micron hollow sphere is provided with reticulate nanopore, wherein, the diameter of the hollow sphere is 1 to 10mum and the aperture of the nanopore is 50 to 100nm; the method of the invention comprises a liquid-phase chemical method, particularly (a) according to the mole ratio that zinc salt: chelating agent: sodium citrate: water is equal to 1:(0.5-1.5):(0.05-0.15):(50-150), the materials are weighted, then put into a vessel, stirred, dissolved and kept warm for three hours at the temperature of 70 to 100 DEG C under the sealing state to obtain a product; (b) the obtained product is filtrated, washed more than one time and heated for 1 to 3 hours at the temperature of 300 to 500 temperature, and the reticulate nanopore zinc-oxide micron hollow sphere is obtained; the zinc salt is zinc nitrate or zinc acetate or zinc chloride or zinc sulfate, and the chelating agent is urea or ammonia or hexamethylene tetramine or ammonium hydroxide. The hollow sphere can be widely applied to the fields of drug transportation, chemical reaction carrier, cosmetics, coating material, catalytic and photocatalysis material, etc.

The invention discloses a sea urchin-shaped hollow gold and silver alloy nano particle and a preparation method and application thereof. The method comprises the following steps: dissolving silver nitrate into water; heating the mixture of the silver nitrate and the water till boiling; adding trisodium citrate aqueous solution in the mixture and keeping boiling for 3-30 minutes to obtain a silver colloid; mixing chloroauric acid aqueous solution and the water; adding the silver colloid under the condition of agitation at the temperature of 15 DEG C; adding hemoporphyrin metalporphyrin aqueous solution and obtaining a reaction solution after 5 min reaction; performing centrifugalization of the reaction solution, washing deposit obtained via centrifugalization, and obtaining the sea urchin-shaped hollow gold and silver alloy nano particle. The diameter of the nano particle is 80 nm-300 nm, the hollow size is 20 nm-50 nm, the length of a stab is 10 nm-30 nm, the diameter of the stab is 10 nm. The preparation method is simple, low in cost, gentle in condition, short in time, easy in process control, and large in production capacity. The obtained nano particle can be well applied to organic molecule detection, earlier detection of tumour and photothermal treatment.

The invention discloses spread processed cheese and a method for preparing the same. The processed cheese comprises the following raw materials in percentage by mass: 10 to 55 percent of natural cheese, 1 to 5 percent of emulsifying salt, 1 to 40 percent of fat product, 0.2 to 1.0 percent of stabilizer and 21 to 56 percent of water, wherein the natural cheese is the fresh curd and / or salt-free cheese; the emulsifying salt is prepared by mixing sodium citrate and potassium phosphate in a mass ratio of 1:9-1:19; the sodium content of the fat product is less than or equal to 60mg / 100g; and the stabilizer can be one or more of glutin, guar gum, microcrystalline cellulose, locust bean gum and modified starch. The spread processed cheese has good taste and texture compared with the conventionalspread processed cheese, and the content of sodium ions is lower than 120mg / 100g, which is 40 to 80 percent less than that of the common cheese; and the spread processed cheese meets the low-sodium food standard and has a stable state and good flavor, tissue and taste. In addition, the preparation method is simple, and easy to implement.