Method for preparing functional gold nanoparticles with high stability

A gold nanoparticle, high-stability technology, applied in the field of material chemistry, can solve problems such as inability to form crystal nuclei, and achieve the effects of improved salt resistance, uniform particle size, and regular shape
CN101987364AInactive Publication Date: 2011-03-23JIANGNAN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
JIANGNAN UNIV
Publication Date
2011-03-23
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a method for preparing functional gold nanoparticles with high stability, which belongs to the technical field of material chemistry. The method comprises the following steps of: the DNA-assisted synthesis of the gold nanoparticles, the salt tolerance experiment of the synthesized gold nanoparticles, the representation of the synthesized gold nanoparticles and the biometric identification of the DNA on the surfaces of the gold nanoparticles. In the method, four kinds of DNAs with three different lengths are utilized and a chloroauric acid is reduced by trisodium citrate to realize the assisted synthesis of the gold nanoparticles; the DNAs of 12 basic groups are obtained by performing representation with an electron microscope to assist in synthesizing the uniform spherical gold nanoparticles, and particularly, the gold nanoparticles obtained by the 12-G-assisted synthesis have regular shapes and a uniform particle size; the salt-tolerant effect of the gold nanoparticles obtained by the salt tolerance experiment of the synthesized gold nanoparticles can be bettered by 20 times; and the gold nanoparticles can enhance the fluorescence of FAM-DNA, and are expected to be well applied to the preparation of nanometer medicaments and nanodevices.
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Description

technical field

[0001] The invention discloses a method for preparing high-stability and functionalized gold nanoparticles, which belongs to the technical field of material chemistry. Background technique

[0002] In recent years, due to the unique properties of gold nanoparticles in optics, chemistry, electronics, catalysis and surface-enhanced Raman scattering spectroscopy, their preparation and application have increasingly aroused the research interest of many scientists. Through the further utilization of these properties of gold nanoparticles, the self-assembly of gold nanoparticles, high-specificity selective catalysis, synthesis of crystal materials, and sensitive sensors are applied.

[0003] So far, there have been many different preparation methods for the preparation of gold nanoparticles, such as trisodium citrate reduction method, sodium borohydride reduction method, trisodium citrate tannic acid reduction method, and seed crystal growth method. The reduction ...

Claims

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