Synthesis method of low-cost cassava polyferose
By modifying cassava starch with a buffer agent and purifying the resulting compound, the method addresses the stability and cost issues of existing sugar-iron complexes, producing a stable and efficient animal feed additive with minimal gastrointestinal irritation.
Patent Information
- Application Number
- CN202510365593.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-26
- Publication Date
- 2025-07-15
AI Technical Summary
The existing polysaccharide iron complex has high preparation cost and poor binding stability, resulting in uneven iron ions release, affecting bioavailability and functionality.
By modifying the tapioca starch and adding buffer additives triethanolamine, ethylenediaminetetraacetic acid and sodium gluconate, the reaction conditions are controlled, and the binding stability of polysaccharides and iron ions are improved, low-cost cassava polysaccharide iron is prepared.
It realizes low-cost and stable preparation of polysaccharide iron, suitable for livestock and poultry iron supplements, has high binding stability and storage performance, and has no irritation to the body's gastrointestinal tract.
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Abstract
Description
Technical Field
[0001] The invention relates to the technical field of biochemical materials, and in particular to a method for synthesizing low-cost cassava polysaccharide iron. Background Art
[0002] Polysaccharides are polymeric carbohydrates composed of more than ten monosaccharides linked by glycosidic bonds. They participate in various physiological activities in the body and play an important role in maintaining normal life activities. They have a wide range of physiological activities, such as lowering blood sugar, anti-oxidation, lowering blood lipids, and anti-virus, and have become another hot spot in functional food research after protein and nucleic acid research. Cassava polysaccharides are a natural polysaccharide extracted from cassava, which is biodegradable, biocompatible and has multiple biological activities. Iron is an important trace element that participates in the active center of multiple enzymes in the body and has physiological functions and biological activities such as anti-oxidation, antibacterial, anti-tumor, and immune regulation.
[0003] Iron is an essential trace element in living organisms. When the body is iron deficient or the utilization of iron is impaired, hemoglobin synthesis will be reduced and the amount of hemoglobin in newly formed red blood cells will be insufficient. Severe iron deficiency will not only cause anemia, but also cause a lack of iron-containing enzymes in the body, leading to cell respiration disorders and affecting the function of tissues and organs. Traditional iron supplements such as ferrous sulfate, although inexpensive, have disadvantages such as low absorption rate and strong gastrointestinal irritation, which limit their application.
[0004] At present, the preparation methods of polysaccharide iron complexes mainly include chemical synthesis and biosynthesis. The chemical synthesis method usually uses iron salts such as ferric chloride and ferrous sulfate to react with different types of polysaccharides under alkaline conditions to prepare polysaccharide iron complexes with different structures and properties, but there are problems such as high preparation cost, poor binding stability of polysaccharides and iron ions, easy dissociation during storage or use, resulting in uneven iron ion release, low iron ion utilization, and low product purity, which reduces the bioavailability and functionality of polysaccharide iron and affects its effect as an iron supplement or functional material.
[0005] Therefore, there is an urgent need to develop a cassava polysaccharide-iron complex that can be used as a feed additive to supplement iron for livestock and poultry, has no irritation to the gastrointestinal tract of the body, has better absorption efficiency, and has the characteristics of low cost, high binding stability, and high storage stability. Summary of the invention
[0006] In view of the above shortcomings, the present invention provides a low-cost synthesis method of cassava polysaccharide iron, which improves the binding stability of polysaccharide and iron ions by modifying cassava starch and adding a buffering aid, improves the storage performance of polysaccharide iron, greatly reduces the cost of raw materials, and has no stimulation to the gastrointestinal tract of the body. The content of sulfate ions is ≤0.3%. The specific technical scheme is as follows:
[0007] A method for synthesizing low-cost cassava polysaccharide iron, characterized by comprising:
[0008] S11. Preparation of cassava starch hydrolysis solution: Add cassava starch to continuously stirred water, stir evenly, add hydrochloric acid, and continuously stir and react at 65 - 75 °C. After the reaction ends, add sodium hydroxide solution to react. After the reaction ends, the hydrolysis solution is obtained;
[0009] S12. Preparation of ferric sulfate: Take ferrous sulfate heptahydrate, dissolve it in water, add hydrogen peroxide to react, and the ferric sulfate solution is obtained after the reaction ends;
[0010] S13. Preparation of cassava polysaccharide iron: Take the hydrolysis solution obtained in step S11 and a certain amount of water, add them to a flask, adjust the pH to 9 - 13, continuously stir and react, add the ferric sulfate solution obtained in step S12, and react for 30 - 70 min to obtain a reaction solution;
[0011] S14. Purification of polysaccharide iron: Take the reaction solution prepared in step S13 for dialysis or membrane treatment. After dialysis or membrane treatment is completed, take it out and dry it to obtain the polysaccharide iron.
[0012] Preferably, in step S11, the mass fraction of sodium hydroxide in the sodium hydroxide solution is 10 - 25%, and the addition amount of the sodium hydroxide solution to the mass of cassava starch is 1 - 2.4:1; the mass fraction of hydrochloric acid is 9 - 25%, and the addition amount to the mass of cassava starch is 0.1 - 0.3:1.
[0013] Preferably, in step S11, the reaction temperature is 45 - 75 °C, and the reaction time is 10 - 20 min.
[0014] Preferably, in step S12, the mass ratio of the hydrolysis solution to the ferric sulfate solution is 20 - 35:10 - 15.
[0015] Preferably, step S12 further includes adding a buffering aid. The buffering aid includes, by mass: 1 - 4 parts of triethanolamine, 1 - 3 parts of ethylenediaminetetraacetic acid, 5 - 10 parts of sodium gluconate, and 40 - 80 parts of water.
[0016] Preferably, the added mass of the buffering aid is 5 times the mass of the modified cassava starch.
[0017] Preferably, the cassava starch is modified cassava starch, and the preparation method includes the following steps:
[0018] S21. Add cassava starch to an oxidant, adjust the solution pH = 3 - 4, react under heating conditions, then continue to raise the temperature for reaction until the viscosity reaches 40 - 60 mPa·s to obtain an oxidized cassava starch solution;
[0019] S22. Disperse the oxidized cassava starch solution in deionized water, cool it to 40 - 50 °C, add amylase and keep it warm for reaction for 1 - 2 hours, then process it with an ultrasonic processor. After the processing is completed, filter and dry to obtain modified cassava starch.
[0020] Preferably, in step S21, the heating temperature is 75 - 80 °C, the heating reaction time is 20 - 60 min, and the temperature increase is 85 - 95 °C.
[0021] Preferably, in step S22, the power of the ultrasonic processor is 200 - 400 W, and the processing time is 1 - 2 h.
[0022] Preferably, the addition amount of the amylase is 0.1% of the mass of the cassava starch.
[0023] Preferably, in step S21, the oxidant is selected from one of ammonium persulfate, potassium persulfate, calcium peroxide, and hydrogen peroxide.
[0024] The present invention provides a low - cost cassava polysaccharide iron, which is prepared by the above - mentioned synthesis method and can be used as a feed additive to play a role in iron supplementation for livestock and poultry.
[0025] Compared with the prior art, the beneficial effects of the present invention are as follows:
[0026] 1. The present invention provides a synthesis method of low - cost cassava polysaccharide iron. By modifying cassava starch and adding a buffering auxiliary agent, the binding stability of the polysaccharide and iron ions is improved, the storage performance of the polysaccharide iron is enhanced, the content of sulfate ions ≤ 0.3%, and the preparation of low - cost cassava polysaccharide iron is realized. And as the main production area of cassava starch in Guangxi, the raw material cost of polysaccharide iron is greatly reduced, and at the same time, the processing and application fields of cassava starch are expanded. The cassava polysaccharide iron prepared by the synthesis method of the present invention can be used as a feed additive to play a role in iron supplementation for livestock and poultry, and it has the characteristics of low cost, no irritation to the gastrointestinal tract and kidneys of the body, stable structure, non - toxic and harmless.
[0027] 2. The buffering auxiliary agent of the present invention is composed of triethanolamine, ethylenediaminetetraacetic acid, and sodium gluconate. It has a coordination ability under alkaline conditions and can form a complex with iron ions. When iron ions bind to cassava polysaccharide, it can provide a certain buffering ability to make the binding of iron ions and cassava polysaccharide more stable. The present invention also controls the dosage ratio among triethanolamine, ethylenediaminetetraacetic acid, and sodium gluconate to avoid the too strong coordination ability of triethanolamine, which may completely wrap iron ions and inhibit their binding with polysaccharide.
[0028] 3. The present invention modifies cassava starch. By controlling the hydrolysis modification conditions of the starch, hydrolysis sugars are obtained according to the needs of the present application. The modification method of the present invention makes the solubility of the system increase, the viscosity decrease, and the swelling power decline through oxidation and enzymatic hydrolysis. The starch molecular chains are partially cut off, exposing more hydroxyl groups. Ultrasonic treatment further destroys the crystalline structure of the starch granules and increases the accessibility of the hydroxyl groups. The modified cassava starch has higher reactivity and improves the binding stability between the polysaccharide and iron ions, extending the storage performance of cassava polysaccharide iron. Detailed Embodiments
[0029] The following describes the detailed embodiments of the present invention in detail, but it should be understood that the protection scope of the present invention is not limited by the detailed embodiments. Unless otherwise defined, all professional terms used hereinafter have the same meaning as commonly understood by those skilled in the art. The professional terms used herein are only for the purpose of describing specific embodiments and are not intended to limit the protection scope of the present invention. Unless otherwise specifically stated, various raw materials, reagents, instruments, and equipment used in the present invention can be obtained through market purchase or can be prepared by existing methods.
[0030] Example 1
[0031] A synthesis method of low-cost cassava polysaccharide iron in this example includes the following steps:
[0032] 1. Preparation of modified cassava starch: Add 25 g of cassava starch to 100 ml of 10% ammonium persulfate solution, adjust the solution pH = 3, heat for reaction, the heating temperature is 50 °C, and the time is 60 min. Then continue to raise the temperature to 85 °C for reaction until the viscosity reaches 60 mPa·s to obtain an oxidized cassava starch solution; Disperse the oxidized cassava starch solution in 100 mL of deionized water, cool to 40 °C, add 0.1% of amylase based on the mass of cassava starch, and keep it warm for reaction for 2 hours. Then use an ultrasonic processor to process it at a power of 200 W for 1 h. After the treatment, filter and dry to obtain modified cassava starch.
[0033] 2. Preparation of cassava starch hydrolyzate: Slowly add 25 g of modified cassava starch to 80 mL of continuously stirred water, stir evenly, then add it to a 250 mL flask, add 5 g of 15% hydrochloric acid, and continuously stir and react at 65 °C for 2 h. After the reaction, add 60 g of 10% sodium hydroxide solution and react for 20 min to obtain the hydrolyzate.
[0034] 3. Preparation of cassava polysaccharide iron: Take 10 g of ferrous sulfate heptahydrate, dissolve it in 50 mL of water, add 20 mL of hydrogen peroxide and react until the green color completely disappears, and the reaction ends to obtain a ferric sulfate solution; Take 20 g of the hydrolysis solution, add 120 mL of water, add 125 g of buffer assistant, add it to a 500 mL flask, adjust the pH to 9, and continuously stir and react at 45 °C for 20 min, then add the prepared ferric sulfate solution and react for 70 min to obtain a reaction solution.
[0035] 4. Purification of polysaccharide iron: Take 50 mL of the reaction solution, put it into a dialysis bag with a molecular weight of 0.5 kDa, dialyze for 12 h, take it out and dry it to obtain cassava polysaccharide iron.
[0036] The buffer assistant in this example includes, by mass: 1 part of triethanolamine, 1 part of ethylenediaminetetraacetic acid, 5 parts of sodium gluconate, and 40 parts of water.
[0037] Example 2
[0038] A synthesis method of low-cost cassava polysaccharide iron in this example includes the following steps:
[0039] 1. Preparation of modified cassava starch: Add 35 g of cassava starch to 100 ml of 10% potassium persulfate solution, adjust the solution pH = 4, heat and react, the heating temperature is 70 °C, and the time is 20 min, then continue to raise the temperature to 95 °C and react until the viscosity reaches 40 mPa·s to obtain an oxidized cassava starch solution; Disperse the oxidized cassava starch solution in 100 mL of deionized water, cool to 50 °C, add 0.1% of amylase based on the mass of cassava starch and keep it warm and react for 1 hour, then use an ultrasonic processor to process it at a power of 400 W for 2 h, after the treatment ends, filter and dry to obtain modified cassava starch.
[0040] 2. Preparation of cassava starch hydrolysis solution: Slowly add 35 g of modified cassava starch to 150 mL of continuously stirred water, stir evenly, then add it to a 250 mL flask, add 5 g of 15% hydrochloric acid, continuously stir and react at 75 °C for 1 h, after the reaction ends, add 40 g of 25% sodium hydroxide solution and react for 40 min to obtain the hydrolysis solution.
[0041] 3. Preparation of cassava polysaccharide iron: Take 20 g of ferrous sulfate heptahydrate, dissolve it in 50 mL of water, add 40 mL of hydrogen peroxide and react until the green color completely disappears, and the reaction ends to obtain a ferric sulfate solution; Take 35 g of the hydrolysis solution, add 150 mL of water, add 175 g of buffer assistant, add it to a 500 mL flask, adjust the pH to 13, and continuously stir and react at 75 °C for 20 min, then add the prepared ferric sulfate solution and react for 50 min to obtain a reaction solution.
[0042] 4. Purification of iron polysaccharide: Take 70 mL of the reaction solution, put it into a dialysis bag with a molecular weight of 0.5 kDa, dialyze for 24 h, take it out and dry it to obtain iron cassava polysaccharide.
[0043] The buffer assistant in this example includes, by mass: 4 parts of triethanolamine, 3 parts of ethylenediaminetetraacetic acid, 10 parts of sodium gluconate, and 80 parts of water.
[0044] Example 3
[0045] A method for synthesizing low-cost iron cassava polysaccharide in this example includes the following steps:
[0046] 1. Preparation of modified cassava starch: Add 28 g of cassava starch to 100 ml of 10% hydrogen peroxide solution, adjust the pH of the solution to 3.5, heat for reaction, the heating temperature is 60 °C, the time is 45 min, then continue to heat up to 90 °C for reaction until the viscosity reaches 50 mPa·s to obtain an oxidized cassava starch solution; Disperse the oxidized cassava starch solution in 100 mL of deionized water, cool to 45 °C and then add 0.1% of the amylase by the mass of cassava starch and keep it warm for reaction for 1.5 hours, then use an ultrasonic processor to process it for 1.5 h at a power of 300 W. After the treatment, filter and dry to obtain modified cassava starch.
[0047] 2. Preparation of cassava starch hydrolysis solution: Slowly add 28 g of modified cassava starch to 120 mL of continuously stirred water, stir evenly, add it to a 250 mL flask, add 7 g of 15% hydrochloric acid, continuously stir and react at 70 °C for 1.5 h. After the reaction, add 50 g of 17% sodium hydroxide solution and react for 30 min to obtain the hydrolysis solution.
[0048] 3. Preparation of iron cassava polysaccharide: Take 15 g of ferrous sulfate heptahydrate, dissolve it in 50 mL of water, add 30 mL of hydrogen peroxide for reaction until the green color completely disappears to end the reaction to obtain a ferric sulfate solution; Take 28 g of the hydrolysis solution, add 135 mL of water, add 140 g of buffer assistant, add it to a 500 mL flask, adjust the pH to 11, at 60 °C, continuously stir and react for 15 min, add the prepared ferric sulfate solution, and react for 50 min to obtain a reaction solution.
[0049] 4. Purification of iron polysaccharide: Take 60 mL of the reaction solution, put it into a dialysis bag with a molecular weight of 0.5 kDa, dialyze for 18 h, take it out and dry it to obtain iron cassava polysaccharide.
[0050] The buffer assistant in this example includes, by mass: 3 parts of triethanolamine, 2 parts of ethylenediaminetetraacetic acid, 7 parts of sodium gluconate, and 60 parts of water.
[0051] Comparative Example 1
[0052] The difference from Example 1 is that the cassava starch in this comparative example is not modified.
[0053] Comparative Example 2
[0054] The difference from Example 1 is that the preparation method of the modified cassava starch in this comparative example is as follows: Add 28 g of cassava starch to 100 ml of 10% hydrogen peroxide solution, adjust the pH of the solution to 3.5, heat to 60 °C, react for 45 min, and after the reaction, evaporate the water to obtain the modified cassava starch.
[0055] Comparative Example 3
[0056] The difference between this comparative example and Example 3 is that this comparative example does not add a buffer assistant.
[0057] Comparative Example 4
[0058] The difference between this comparative example and Example 3 is that this comparative example does not add triethanolamine to the buffer assistant.
[0059] Comparative Example 5
[0060] The difference between this comparative example and Example 3 is that this comparative example does not add ethylenediaminetetraacetic acid to the buffer assistant.
[0061] Comparative Example 6
[0062] The difference between this comparative example and Example 3 is that this comparative example does not add sodium gluconate to the buffer assistant.
[0063] 1. Binding stability test
[0064] Determine the iron content in the ferric sulfate solution by the potassium dichromate method, and then determine the chelation rate of cassava polysaccharide iron by the dialysis method. Take 2 mL of the sample and carbonize it on an electric furnace for 2 h, and then incinerate it in a muffle furnace at 550 °C for 3 h to obtain the ash. Take a certain amount of the incinerated sample, dissolve it in an appropriate amount of water, transfer it to a 50 mL volumetric flask, and successively add 1 mL of 6 mol / L HCl, 2 mL of 10% hydroxylamine hydrochloride, 5 mL of 1 mol / L NaAC, and 1 mL of 0.15% o-phenanthroline for color development and volume fixation, and then determine the iron content in the ash by the o-phenanthroline colorimetric method at 510 nm. The chelation rate of cassava polysaccharide iron is calculated by the following formula:
[0065] Chelation rate = (iron content in ferric sulfate ÷ iron content in the ash of the sample) × 100%
[0066] The test results are shown in Table 1 below.
[0067] Table 1
[0068]
[0069]
[0070] 2. Test for Sulfate Ion Content
[0071] For Examples 1 - 3, the test for sulfate ion content was carried out with reference to the national standard GB / T 27983--2011.
[0072] Under acidic conditions, barium chloride was used to precipitate sulfate ions as barium sulfate. After the precipitate was filtered, washed, and calcined, it was weighed in the form of barium sulfate, and the sulfate content calculated as sulfate was obtained.
[0073] Weigh about 1 g of the sample (accurate to 0.01 g) into a 250 mL beaker, add 100 mL of water, heat in a boiling water bath, add 2 mL of hydrochloric acid dropwise, continue heating until completely dissolved, and then filter. Heat the filtrate to boiling, take it off, and slowly add 10 mL of barium chloride solution (weigh 10 g of barium chloride and dissolve it in 100 mL of water) dropwise. Keep it in a boiling water bath for 2 h, take it out, cover it, and let it stand overnight. If ferrous fumarate crystals form, warm it on a boiling water bath to dissolve it, then filter it with a quantitative filter paper, wash the residue with hot water, and use silver nitrate solution (weigh 1.75 g of silver nitrate and dissolve it in 100 mL of water, store it in a brown reagent bottle) to test that there is no white precipitate in the filtrate. Transfer the residue and the filter paper to a crucible that has been weighed to a constant weight, char it gently on a temperature-controlled electric furnace, and calcine the crucible and its contents at 800 °C until a constant weight is reached (the difference in mass between two weighings is less than 0.001 g). The calculation formula is as follows.
[0074] X = (m4 × 0.412) / m5 × 100%
[0075] X —— Sulfate ion content;
[0076] m4 —— Mass of the precipitate, in grams (g);
[0077] 0.412 —— Conversion coefficient of barium sulfate to sulfate ion;
[0078] m5 —— Mass of the sample taken, in grams (g).
[0079] Retain two significant figures, and take the arithmetic mean of the results of two parallel determinations as the determination result. As shown in Table 2 below.
[0080] Table 2
[0081] Group Sulfate ion content (%) Example 1 0.20 Example 2 0.23 Example 3 0.28
[0082] 3. Detection of Gastrointestinal Adaptability of the Body
[0083] After 30 mice were fed adaptively for 1 week, they were administered cassava polysaccharide iron at a dose of 200 mg / kg once a day for 14 consecutive days by gavage. On the 14th day of administration, the livers and kidneys of the mice were collected, and on the 28th day, the colons of the mice were collected to observe the pathological changes of each tissue. The observation showed that the liver structure of the mice was clear and normal, desmosomes were visible, the hepatocytes were radially arranged around the central vein, the structures of the hepatocytes and hepatic lobules were both intact, the cells were closely and orderly distributed, and there were no lesions; the structure of the renal units of the mice was clear, the organizational structures of the glomeruli and renal tubules at all levels were intact, and there were no lesions; the organizational structures of the intestinal mucosa layer, submucosa layer, muscular layer, and serosa layer of the mice were normal, the intestinal glands were rich and arranged regularly, the villi were arranged neatly and had a high density, and the structures and morphologies of the intestinal villi and crypts were normal.
[0084] In summary, the present invention provides a synthesis method of low-cost cassava polysaccharide iron. By controlling the hydrolysis modification conditions of starch, hydrolysis sugars are obtained from starch according to the requirements of the present application. In the modification method of the present invention, through oxidation and enzymatic hydrolysis, the solubility of the system increases, the viscosity decreases, the swelling power decreases, the starch molecular chains are partially cut off, more hydroxyl groups are exposed, and ultrasonic treatment further destroys the crystalline structure of starch granules and increases the accessibility of hydroxyl groups. The modified cassava starch has higher reactivity, and by adding a buffer auxiliary agent, the binding stability of the polysaccharide and iron ions is improved, the storage performance of the polysaccharide iron is enhanced, the content of sulfate ions is ≤0.3%, and the preparation of low-cost cassava polysaccharide iron is realized. Moreover, as the main production area of cassava starch, Guangxi greatly reduces the raw material cost of polysaccharide iron and also expands the processing and application fields of cassava starch. The cassava polysaccharide iron prepared by the synthesis method of the present invention can be used as a feed additive to supplement iron for livestock and poultry, and it has the characteristics of low cost, no irritation to the gastrointestinal tract and kidneys of the body, stable structure, non-toxic and harmless. The buffer auxiliary agent of the present invention is composed of triethanolamine, ethylenediaminetetraacetic acid, and sodium gluconate. It has strong coordination ability under alkaline conditions, can form very stable complexes with iron ions, can increase the solubility of iron ions, promote their combination with cassava polysaccharide, and can provide a certain buffering capacity. The present invention also controls the dosage ratio of triethanolamine, ethylenediaminetetraacetic acid, and sodium gluconate to avoid the over-strong coordination ability of triethanolamine from inhibiting its combination with polysaccharide. The present invention also modifies cassava starch, oxidizes and hydrolyzes cassava starch and crosslinks it with hydrophilic polymers, so that the solubility of the system increases, the viscosity decreases, and the swelling power decreases, thereby improving the chelation rate of cassava polysaccharide and iron ions, enhancing the binding stability of the polysaccharide and iron ions, and prolonging the storage performance of cassava polysaccharide iron.
[0085] The foregoing description of the specific exemplary embodiments of the present invention is for illustrative and exemplifying purposes. These descriptions are not intended to limit the present invention to the precise forms disclosed, and obviously, many changes and variations can be made in accordance with the above teachings. The purpose of selecting and describing the exemplary embodiments is to explain the specific principles of the present invention and its practical applications, so that those skilled in the art can implement and utilize various different exemplary embodiments of the present invention, as well as various different selections and changes. The scope of the present invention is intended to be defined by the claims and their equivalents.
Claims
1. A method for synthesizing low-cost cassava polysaccharide iron, characterized in that, It includes the following steps: S11. Preparation of cassava starch hydrolysate: Add cassava starch into continuously stirred water. After stirring evenly, add hydrochloric acid and continuously stir and react at 65 - 75 °C. After the reaction ends, add sodium hydroxide solution to react. After the reaction ends, the hydrolysate is obtained; S12. Preparation of ferric sulfate: Take ferrous sulfate heptahydrate, dissolve it in water, add hydrogen peroxide to react, and the ferric sulfate solution is obtained after the reaction ends; S13. Preparation of cassava polysaccharide iron: Take the hydrolysate obtained in step S11 and a certain amount of water, add them into a flask, adjust the pH to 9 - 13, continuously stir and react, add the ferric sulfate solution obtained in step S12, and react for 30 - 70 min to obtain a reaction solution; S14. Purification of polysaccharide iron: Take the reaction solution prepared in step S13 for dialysis or membrane treatment. After dialysis or membrane treatment is completed, take it out and dry it to obtain the polysaccharide iron.
2. The synthesis method of a low-cost cassava polysaccharide iron according to claim 1, characterized in that, In the step S11, the mass fraction of sodium hydroxide in the sodium hydroxide solution is 10 - 25%, and the addition amount of the sodium hydroxide solution to the mass of cassava starch is 1 - 2.4:1; the mass fraction of hydrochloric acid is 9 - 25%, and the addition amount to the mass of cassava starch is 0.1 - 0.3:
1.
3. A method for synthesizing low-cost cassava polysaccharide iron according to claim 1, characterized in that, In the step S11, the reaction temperature is 45 - 75 °C, and the reaction time is 10 - 20 min.
4. A method for synthesizing low-cost cassava polysaccharide iron according to claim 1, characterized in that, In the step S13, the mass ratio of the hydrolysate to the ferric sulfate solution is 20 - 35:10 - 15.
5. A method for synthesizing low-cost cassava polysaccharide iron according to claim 1, characterized in that, In the step S13, a buffering auxiliary agent is also included. The buffering auxiliary agent includes, by mass: 1 - 4 parts of triethanolamine, 1 - 3 parts of ethylenediaminetetraacetic acid, 5 - 10 parts of sodium gluconate, and 40 - 80 parts of water.
6. A method for synthesizing low-cost cassava polysaccharide iron according to claim 1, characterized in that, The cassava starch is modified cassava starch, and the preparation method includes the following steps: S21. Add cassava starch into an oxidant, adjust the solution pH = 3 - 4, react under heating conditions, and then continue to raise the temperature for reaction until the viscosity reaches 40 - 60 mPa·s to obtain an oxidized cassava starch solution; S22. Disperse the oxidized cassava starch solution in deionized water, cool it to 40 - 50 °C, add amylase and keep it warm for reaction for 1 - 2 hours, then use an ultrasonic processor to process. After the processing ends, filter and dry to obtain modified cassava starch.
7. A method for synthesizing low-cost cassava polysaccharide iron according to claim 6, characterized in that, In the step S21, the heating temperature is 75 - 80 °C, the heating reaction time is 20 - 60 min, and the temperature increase is 85 - 95 °C.
8. A method for synthesizing a low-cost cassava polysaccharide iron according to claim 6, characterized in that In the step S22, the power of the ultrasonic processor is 200 - 400 W, and the processing time is 1 - 2 h.
9. A method for synthesizing low-cost cassava polysaccharide iron according to claim 6, characterized in that, In the step S21, the oxidant is selected from one of ammonium persulfate, potassium persulfate, calcium peroxide, and hydrogen peroxide.
10. A low-cost cassava polysaccharide iron, characterized in that, The cassava polysaccharide iron is prepared by the synthesis method described in any one of claims 1 to 9.