The invention discloses a traditional Chinese medicine and western medicine combined preparation for treating antepartum eclampsia and a preparation method, and belongs to the technical field of medicines. Active ingredients of the traditional Chinese medicine and western medicine combined preparation provided by the invention comprise the following raw materials: vitamin B1, bepridil, polysaccharide-iron complex, radix rhododendri simsii, pedes suillus, rubus alexeterius, folium rumicis, retinervus luffae fructus, herba scutellariae orthocalycis, calculus macacae mulattae, herba renantherae coccineae, circaea alpina, herba lysimachia hypericoides hemsl, rhizoma et radix oryzae glutinosae, caulis vitis quinquangularis, herba equiseti hiemalis and pilea pumila. The traditional Chinese medicine and western medicine combined preparation is prepared by combining traditional Chinese medicines with western medicines, has significant efficacy for treatment of antepartum eclampsia-induced meridian spasm, throbbing pain of limbs, wander in mind and other symptoms, is short in treatment course, fast to take effect, high in cure rate, safe and reliable, free of toxic and side effects, convenient to take and low in cost, and also has the effects of clearing liver to stop wind, stopping bleeding and preventing miscarriage, tranquilizing the mind and relieving spasm.