Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

143 results about "Gynostemma pentaphyllum" patented technology

Gynostemma pentaphyllum, also called jiaogulan (Chinese: 絞股藍, Pinyin: jiǎogǔlán, literally "twisting blue plant") is a dioecious, herbaceous climbing vine of the family Cucurbitaceae (cucumber or gourd family) widely distributed in South and East Asia as well as New Guinea. Jiaogulan has recently been incorporated into traditional medicine, although there is no evidence-based medicine that demonstrates any effects on human health.

Composition with functions of reducing blood sugar and blood fat as well as preparation method and application of composition

The invention belongs to the technical field of biological medicines, and particularly discloses a composition with functions of reducing blood sugar and blood fat as well as a preparation method and application of the composition. Chinese herbal compound medicinal materials are subjected to water extraction and high-temperature and high-pressure sterilization, and lactobacillus rhamnosus SHA113 bacterial sludge is resuspended in a water extract to obtain the composition of lactobacillus rhamnosus SHA113 and the Chinese herbal compound; the traditional Chinese medicine compound composition comprises astragalus membranaceus, raw Chinese yam, hawthorn, gynostemma pentaphylla, liquorice and jujube; the preservation number of the lactobacillus rhamnosus SHA113 is CCTCC (China Center For Type Culture Collection) NO: M 2017838; the lactobacillus rhamnosus SHA113 and traditional Chinese medicine compound composition can remarkably reduce the content of triglyceride and cholesterol in serum, control the fasting blood-glucose level, relieve accumulation of triglyceride and cholesterol in the liver and improve the oxidation resistance of the liver, has wide market potential and application prospects, and has wide application prospects. The compound can be applied to preparation of drugs for reducing blood sugar and blood fat.
Owner:NORTHWESTERN POLYTECHNICAL UNIV

Cleaning mud mask capable of clearing pores and preparation method of cleaning mud mask

The invention discloses a pore cleaning mud mask and a preparation method thereof, belongs to the technical field of cosmetics, and particularly relates to a pore cleaning mud mask. Comprising 14 to 18 parts of kaolin, 7 to 9 parts of Manny root ice river mud, 4.5 to 5.5 parts of Amazon white mud, 10 to 12 parts of wheat germ oil, 43 to 47 parts of tea water, 0.1 to 0.14 part of a phellinus linteus extract, 1 to 2 parts of swertia mileensis powder, 2 to 4 parts of lactobionic acid, 0.08 to 0.12 part of salicylic acid and 0.4 to 0.6 part of gluconolactone. The pore cleaning mud mask provided by the invention is uniform in particle size distribution, uniform in mixing and capable of keeping the state of the mud mask moist and not dry in the use process, the cleaning strength of controlling oil, dredging pores and resisting inflammation is improved, meanwhile, skin sensitivity caused by excessive cleaning is avoided, and the cleaning effect is good. The invention provides a novel cleaning mud mask formula for realizing the goal of cleaning pores and an efficient and stable preparation method of the novel cleaning mud mask formula.
Owner:BEAUTIFUL LINK (GUANGDONG) BIOTECHNOLOGY CO LTD

Preparation process of phlegm-eliminating and blood-activating granules and application of phlegm-eliminating and blood-activating granules in metabolism-related fatty liver diseases

The invention belongs to traditional Chinese medicine formula granules, and particularly relates to a preparation process of phlegm-eliminating and blood-activating granules and application of the phlegm-eliminating and blood-activating granules in metabolism-related fatty liver diseases. The granule comprises gynostemma pentaphylla and raw hawthorn which are used as monarch drugs, raw bighead atractylodes rhizome, rhodiola rosea and turmeric which are used as ministerial drugs, and auxiliary materials for preparing the granule. The granules with the formula for eliminating phlegm and activating blood, which are researched and developed by the invention, have the characteristics of stable property, convenience in transportation, carrying, storage and use and the like. The preparation technology is high in production efficiency and has good economic value, and the prepared granules can effectively exert the pesticide effect.
Owner:MEI HOSPITAL UNIV OF CHINESE ACAD OF SCI +2

Oil-controlling, soothing and repairing composition and preparation method thereof

The invention discloses an oil-controlling, soothing and repairing composition and a preparation method thereof. The oil-controlling, soothing and repairing composition is prepared from a herba portulacae extract, a herba centellae extract, a baropetalum chinense leaf extract and a plankton extract. According to multiple experimental researches, the composition obtained by compounding the extracts has excellent effects of controlling oil, inhibiting activity of propionibacterium acnes, relieving and repairing, is mild and non-irritant, and has a good popularization and application prospect.
Owner:DOCTOR PLANT GUANGDONG BIOTECHNOLOGY CO LTD

Roegneria ciliata PmRc1 gene, protein coded by roegneria ciliata PmRc1 gene and application of roegneria

The invention discloses a roegneria ciliata PmRc1 gene, a protein coded by the roegneria ciliata PmRc1 gene and application of the roegneria ciliata The sequence of the powdery mildew resistance gene PmRc1 is derived from a small fragment translocation line TT-7 created by tetraploid roegneria ciliata and common wheat, the nucleotide sequence of the powdery mildew resistance gene PmRc1 is SEQ ID NO.1, and the amino acid sequence of the powdery mildew resistance gene PmRc1 is SEQ ID NO.2. The roegneria ciliata PmRc1 gene and the recombinant expression vector are applied to cultivation of wheat varieties with powdery mildew resistance. According to the candidate gene of the powdery mildew resistance gene PmRc1 derived from roegneria ciliata, the susceptibility can be enhanced by silencing the gene in a disease-resistant material, and the powdery mildew resistance can be improved by overexpressing the gene. The invention has important significance on wheat powdery mildew resistance breeding.
Owner:NANJING AGRICULTURAL UNIVERSITY

A traditional Chinese medicine composition and application thereof in preparation of a traditional Chinese medicine eye patch for treating thyroid eye disease

PendingCN122351337AOcular inflammationThyroid
This invention provides a traditional Chinese medicine composition and its application in the preparation of a topical herbal eye patch for treating thyroid eye diseases, belonging to the field of biomedical technology. The herbal composition consists of *Gynostemma pentaphyllum*, peppermint, *Platycladus orientalis* leaves, borneol, cicada slough, *Astragalus membranaceus*, *Selaginella tamariscina*, *Pteris vittata*, *Scutellaria baicalensis*, apricot leaf, and *Ipomoea aquatica*. Using this herbal composition as raw material, a topical herbal eye patch is prepared. This patch acts directly on acupoints and skin around the eyes, allowing the medicinal properties to penetrate the skin and reach the eye system, achieving the effects of promoting blood circulation, clearing heat and detoxifying, invigorating qi and unblocking meridians, reducing swelling and improving vision. It is suitable for the treatment of thyroid-related eye diseases. This invention's topical herbal eye patch can effectively improve clinical symptoms such as exophthalmos and eye inflammation in patients with thyroid eye diseases, positively impacting their quality of life and effectively improving the clinical treatment efficacy of this disease. The topical herbal eye patch provided by this invention can be further promoted and applied in the clinical treatment of thyroid eye diseases.
Owner:THE FIRST AFFILIATED HOSPITAL OF HENAN UNIV OF TCM

Chinese herbal medicine preparation for treating avian infectious bronchitis virus variant infection

The invention provides a Chinese herbal medicine preparation for treating avian infectious bronchitis virus variant infection, and relates to the technical field of medicine preparation. The Chinese herbal medicine preparation for treating avian infectious bronchitis virus variant infection is prepared from the following components in parts by weight: 12-20 parts of gynostemma pentaphyllum, 8-12 parts of fructus forsythiae, 4-8 parts of folium isatidis, 4-8 parts of honeysuckle, 12-20 parts of platycodon grandiflorum, 8-12 parts of perillaseed, 4-8 parts of codonopsis pilosula, 4-8 parts of scutellaria baicalensis and 4-8 parts of radix sophorae flavescentis. The Chinese herbal medicines are decocted into liquid medicine to feed poultry, bronchitis and complications caused by virus variant infection can be effectively treated, the physique of the poultry is enhanced, the immunity of the poultry is improved, the death rate of the poultry is reduced, the Chinese herbal medicines are decocted into the liquid medicine, feeding is easy, cost is low, and the Chinese herbal medicines are suitable for large-scale popularization and application. Even if the composition is taken for a long time, drug resistance generated in poultry bodies is low, and drug property residual quantity is small.
Owner:SHANDONG PROVINCIAL CENT FOR ANIMAL DISEASE CONTROL & PREVENTION

Application of gynostemma pentaphyllum saponin H combined with azole drugs in preparation of antifungal drugs and antifungal drugs

PendingCN122643315AImprove synergistic antibacterial effectAddressing drug resistanceAntifungal drugCandida auris
The application discloses application of gynostemma pentaphyllum saponin H combined with azole drugs in preparation of antifungal drugs and the antifungal drugs, and relates to the technical field of antifungal drugs. It is found through systematic in-vitro drug sensitivity test that natural product gynostemma pentaphyllum saponin H combined with specific azole antifungal drugs (especially posaconazole POS) can produce significant synergistic antifungal effect, especially for clinical thorny aspergillus, candida, new cryptococcus and dark fungi. The combination strategy can significantly reduce the minimum inhibitory concentration of azole drugs, reverse drug resistance, and is effective for multi-drug resistant strains (such as candida auris). The application provides an efficient and low-toxicity new combination drug scheme for overcoming the increasingly serious fungal drug resistance problem.
Owner:JINGZHOU CENT HOSPITAL (JINGZHOU HOSPITAL AFFILIATED TO YANGTZE UNIV)

Traditional Chinese medicine fumigation bag for relieving eye fatigue and preparation method and application thereof

The invention discloses a traditional Chinese medicine fumigation bag for relieving eye fatigue and a preparation method and application thereof, and belongs to the technical field of eye medicine. The traditional Chinese medicine fumigation bag for relieving eye fatigue is prepared from the following components in parts by weight: 10 to 30 parts of flos chrysanthemi indici, 10 to 30 parts of frosted folium mori, 10 to 30 parts of semen cassiae, 10 to 30 parts of herba gynostemmatis pentaphylli, 5 to 20 parts of herba menthae, 5 to 20 parts of folium perillae and 5 to 20 parts of herba dendrobii. According to the traditional Chinese medicine fumigation bag, through formula design, a slow release technology and a double-layer packaging technology, the defects that in the prior art, the medicine effect is short, and components are prone to losing are overcome, and the effect of a traditional fumigation therapy method is remarkably improved.
Owner:ZHENGZHOU YAOSHIDA HEALTH TECHNOLOGY CO LTD

Traditional Chinese medicine composition as well as preparation and application thereof

The invention belongs to the field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition and a preparation and application thereof. A compatibility system of monarch, minister, assistant and guide is adopted, rhizoma atractylodis, semen coicis and cortex phellodendri are taken as monarch drugs, polygonum cuspidatum, centella asiatica and fructus kochiae are taken as minister drugs, prepared rheum officinale, radix achyranthis bidentatae and caulis spatholobi are taken as guide drugs, gynostemma pentaphyllum, radix paeoniae alba and rhizoma polygonati are taken as adjuvant drugs, the medicinal materials are compounded according to a specific mass ratio, and the mass ratio of the monarch drugs to the minister drugs to the adjuvant drugs to the guide drugs is (50-80): (50-80): (30-55): (35-70). The traditional Chinese medicine composition provided by the invention can remarkably reduce the levels of blood uric acid, serum creatinine and urea nitrogen, reduce urine protein excretion and improve inflammation, a hypercoagulation state and lipid metabolism disorder, the total effective rate reaches 90%, the adverse reaction is slight, and the recurrence rate is low.
Owner:SHANGHAI PUDONG NEW AREA PEOPLES HOSPITAL

Compositions for removing dampness, controlling blood sugar, balancing blood pressure, and regulating blood lipids, and their applications.

PendingCN122296456ABiotechnologyMedicinal herbs
This invention relates to the field of health products or food technology, and more specifically to a composition and its application in removing dampness and controlling blood sugar, balancing blood pressure, and regulating blood lipids. The invention provides a composition for removing dampness and controlling blood sugar, balancing blood pressure, and regulating blood lipids, comprising Poria cocos extract, Astragalus membranaceus extract, hirudin, and at least one or more of Eucommia ulmoides extract, Gynostemma pentaphyllum extract, and Morus alba twig extract. The composition provided by this invention utilizes extracts from at least four precious Chinese medicinal herbs to exert a synergistic effect, jointly achieving the effects of lowering blood pressure, removing dampness and lowering blood sugar, and lowering blood lipids.
Owner:SHANGHAI DINGYA PHARM CHEM CO LTD

Traditional Chinese medicine compound for treating viral myocarditis

ActiveCN121401357BAntiviralsCardiovascular disorderViral MyocarditisCitrus medica
This invention provides a traditional Chinese medicine compound for treating viral myocarditis, belonging to the field of traditional Chinese medicine pharmaceutical technology. The compound consists of Forsythia suspensa, Fagopyrum dibotrys, Pseudostellaria heterophylla, Rhodiola rosea, Citrus medica, Allium macrostemon, Poria cocos, Gynostemma pentaphyllum, Salvia miltiorrhiza, Dalbergia odorifera, Cynanchum paniculatum, and Valeriana. This traditional Chinese medicine compound exhibits significant protective effects against viral myocarditis, specifically by significantly reducing damage to H9c2 cardiomyocytes caused by CVB3 virus. Its mechanism of action is closely related to downregulating the expression of inflammatory factors TNF-α and IL-6 and inhibiting the inflammatory response. Simultaneously, within the experimental concentration range, the compound shows no toxicity to cardiomyocytes, demonstrating good biocompatibility. Furthermore, this compound can significantly reduce myocardial tissue damage in a viral myocarditis model mouse by inhibiting the in vivo inflammatory response and regulating oxidative stress imbalance, providing a safe and effective new treatment option for the clinical treatment of viral myocarditis.
Owner:THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIV

Traditional Chinese medicine formula for treating high perianal abscess postoperative wound

The invention discloses a traditional Chinese medicine formula (Shenhuang decoction) for treating postoperative wounds of high-order perianal abscess, belongs to the field of traditional Chinese medicines, and aims to solve the problems of wound infection, slow healing and obvious pain and edema after the high-order perianal abscess. The formula is based on 30 g of radix sophorae flavescentis, 20 g of cortex phellodendri, 15 g of radix angelicae, 6 g of radix arnebiae seu lithospermi, 15 g of frankincense, 15 g of radix angelicae sinensis, 10 g of rhizoma bletillae, 10 g of resina draconis and 3 g of borneol, and increase and decrease are carried out according to symptoms: when swelling is obvious, peach kernels and spina gleditsiae (leeches and earthworms are added, when secretion is more, astragalus membranaceus is reinforced, when bleeding occurs, pseudo-ginseng and hairyvein agrimony are added, honeysuckle stems are added when heat is excessive, and when the mouth is not closed for a long time, codonopsis pilosula, rhodiola rosea, gynostemma pentaphyllum and gallnut are added. The preparation adopts an ultrasonic atomization liquid form, is prepared by decocting with water and taking 400ml of juice (at 38 DEG C), and is atomized, fumigated and washed for 15 minutes once in the morning and once in the evening every day, and is matched with conventional dressing change. The traditional Chinese medicine composition can clear away heat and toxic materials, promote blood circulation to arrest pain, remove slough and promote granulation, reduce the level of TNF-alpha and IL-6, shorten the wound healing time and relieve pain and edema, and is suitable for wound recovery after high perianal abscess operation.
Owner:YIBIN HOSPITAL OF TRADITIONAL CHINESE MEDICINE

A traditional Chinese medicine composition with the functions of improving immunity and tonifying qi and anti-aging and application thereof

The application provides a traditional Chinese medicine composition with the functions of improving immunity and tonifying qi and resisting aging and application thereof. The traditional Chinese medicine composition comprises the following components in mass fractions: green tea 2255 parts, Gynostemma pentaphyllum 1000 parts, Astragalus extract 625 parts, Lycium barbarum fruit extract 600 parts, Ligustrum lucidum fruit extract 420 parts and Ganoderma lucidum extract 100 parts. The traditional Chinese medicine composition has the functions of improving immunity and tonifying qi and resisting aging through the synergistic effect of the multiple components.
Owner:GUANGZHOU TIANCHEN YIPIN TECH CO LTD

A hot compress for treating scleroderma and a preparation method thereof

This invention belongs to the technical field of skin disease treatment products, specifically relating to a topical hot compress for treating scleroderma and its preparation method. The topical hot compress for treating scleroderma is made from the following raw materials in parts by weight: 20-40 parts of Artemisia argyi, 20-40 parts of Cinnamomum cassia, 10-20 parts of Sparganium stoloniferum, 10-20 parts of Curcuma zedoaria, 10-20 parts of Loranthus parasiticus, 15-30 parts of Gynostemma pentaphyllum, 10-20 parts of Spirodela polyrhiza, 15-30 parts of Spirodela polyrhiza, 15-30 parts of Ephedra sinica, 20-40 parts of Clematis chinensis, 5-15 parts of Eupolyphaga sinensis, 15-25 parts of Eriocaulon buergerianum, 5-15 parts of Carthamus tinctorius, 3-6 parts of Dracaena cochinchinensis, 3-6 parts of processed Strychnos nux-vomica, 20-40 parts of Vaccaria segetalis, 20-40 parts of Astragalus membranaceus, 10-20 parts of Magnolia officinalis, 10-20 parts of Aconitum carmichaelii, and 22-40 parts of rice wine. This invention is a topical medication that eliminates the need for oral administration, treating the disease externally and guiding the pathogenic factors to a cure. It avoids the inconvenience of bitter medications and effectively relieves symptoms and promotes the cure of localized scleroderma.
Owner:SHAANXI PROVINCIAL HOSPITAL OF CHINESE MEDICINE

Myocardial protection traditional Chinese medicine composition for clearing heat, promoting blood circulation and removing blood stasis, preparation as well as preparation method and application of myocardial protection traditional Chinese medicine composition

The invention relates to the technical field of pharmaceutical preparations, in particular to a myocardial protection traditional Chinese medicine composition capable of clearing heat, promoting blood circulation and removing blood stasis, a preparation and a preparation method and application of the myocardial protection traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following medicinal materials in parts by weight: 5-15 parts of gentiana acuminata, 10-20 parts of salvia miltiorrhiza, 5-15 parts of angelica sinensis, 10-20 parts of gynostemma pentaphylla, 5-15 parts of rhodiola rosea, 3-10 parts of hematoxylon, 5-15 parts of radix paeoniae rubra, 3-10 parts of lumbricus, 3-10 parts of radix curcumae, 10-20 parts of astragalus membranaceus, 3-10 parts of ginseng, 5-15 parts of radix ophiopogonis, 3-8 parts of schisandra chinensis and 3-8 parts of liquorice. According to the traditional Chinese medicine compound provided by the invention, through the synergistic effect of clearing heat, promoting blood circulation, removing blood stasis, tonifying qi and nourishing yin, the synergistic effect can be achieved more comprehensively aiming at the pathogenesis of heat-blood stasis intermingling. The traditional Chinese medicine composition has remarkable advantages in the aspect of treating myocardial ischemia reperfusion injury, the curative effect of the traditional Chinese medicine composition depends on complete monarch, minister, assistant and guide compatibility, and the overall medicine effect can be reduced if part of components are lost.
Owner:HEILONGJIANG UNIV OF CHINESE MEDICINE

Preparation process of partridge tea and tea beverage

The application provides a preparation process of tea of fructus phoebe and a tea beverage containing the tea of fructus phoebe. The preparation process of the tea of fructus phoebe comprises the following steps: S1, taking fresh tea leaves of fructus phoebe, drying, crushing, passing through a 40-100 mesh sieve and adding water; S2, adding a compound enzyme for enzymolysis; S3, deactivating the enzyme, filtering and obtaining an extract containing the tea of fructus phoebe. Through compounding ingredients such as gynostemma pentaphyllum and fat sea cucumber, the tea beverage has high stability, good taste and high content of bioactive components, and has wide application value and market prospect.
Owner:HAINAN ZHEGU TEA BEVERAGE CO LTD

Xianjing wolfberry wine and preparation method thereof

The invention provides herba epimedii, wolfberry fruit and lucid ganoderma wine and a preparation method thereof, and relates to the technical field of medicinal liquor. The folium mori, fructus lycii, lycium ruthenicum, ganoderma lucidum, wall-broken ganoderma lucidum spore powder, mulberry, astragalus membranaceus, dendrobe, enzymolysis silkworm chrysalis meal, red yeast rice, clove, ligusticum wallichii, angelica sinensis, semen cassiae, agastache rugosus and other raw materials are subjected to pretreatment, fermentation and post-treatment to obtain the folium mori, fructus lycii, lycium ruthenicum, ganoderma lucidum, wall-broken ganoderma lucidum spore powder, mulberry, astragalus membranaceus, dendrobe, enzymolysis silkworm chrysalis meal, red yeast rice The Xianjing wolfberry wine disclosed by the invention has multiple effects of resisting oxidation, protecting the liver, improving eyesight and the like, is good in sensory quality and high in standardization degree of the preparation process, and has good industrial application prospects and economic benefits.
Owner:HANDAN DOUMO LIQUOR CO LTD

Method for producing a plant-based extract composition having the effect of enhancing nutrition and immunity

A method for producing a plant-based extract composition having the effect of enhancing nutrition and immunity comprises the following steps: (i) preparing materials; (ii) creating a base mixture; (iii) creating a foundation mixture; (iv) creating a first temporary mixture; (v) creating a second temporary mixture; (vi) creating a uniform mixture; (vii) creating a post-incubation mixture; and (viii) concentrating the post-incubation to obtain the plant-based extract composition having the effect of enhancing nutrition and immunity. This composition includes the following components: Ngoc Linh ginseng (Panax vietnamensis) extract; jiaogulan (Gynostemma pentaphyllum) powder; maingay's tree (Cratoxylum maingayi) powder; nodding clubmoss (Lycopodiella cernua) powder; red ginseng (Radix Ginseng Rubra) powder; codonopsis root (Codonopsis pilosula) powder; angelica root (Angelica sinensis) powder; rice bran oil, legume powder; coenzyme Q10; ginsenoside Rb1 extract; and honey.
Owner:NGUYEN THUY AN THI

Special medicine for treating adolescent acne and its preparation process

This application relates to the field of traditional Chinese medicine compositions, specifically disclosing a special medicine for treating adolescent acne and its preparation process. The preparation process comprises the following steps: Step 1: pulverize turmeric and extract with steam distillation to obtain a turmeric single extract and turmeric residue; pulverize coral ginger and extract with steam distillation to obtain a coral ginger single extract and coral ginger residue; pulverize Gynostemma pentaphyllum, Solidago asiatica, and Paris polyphylla into fine powders, mix them with the turmeric residue and coral ginger residue, and macerate with ethanol to collect the percolate; decoct Radix Angelicae Dahuricae and Schizonepeta tenuifolia with water, filter, and concentrate the filtrate to obtain a clear paste, add ethanol, let stand, and filter to obtain an alcohol precipitate; the alcohol precipitate and the percolate are mixed to obtain a mixed solution; Step 2: emulsify the turmeric single extract and coral ginger single extract, respectively, and mix them with the mixed solution to obtain the special medicine. This medicine has the advantages of improving the therapeutic effect on acne while further reducing pigmentation.
Owner:GUIYANG SHUMEIDA PHARM CO LTD

A kidney-nourishing and phlegm-dissolving traditional Chinese medicine compound, a preparation method thereof and an anti-atherosclerosis application thereof

This invention belongs to the field of traditional Chinese medicine technology, and discloses a kidney-tonifying and turbidity-resolving traditional Chinese medicine compound, its preparation method, and its anti-atherosclerotic application. The effective components of the kidney-tonifying and turbidity-resolving traditional Chinese medicine compound, by mass, consist of 15 parts Rehmannia glutinosa (processed), 15 parts Astragalus membranaceus (raw), 9 parts Cistanche deserticola, 10 parts Nelumbo nucifera (lotus leaf), 20 parts Gynostemma pentaphyllum, 12 parts Crataegus pinnatifida, and 6 parts Citrus reticulata (dried tangerine peel). The preparation method of the kidney-tonifying and turbidity-resolving traditional Chinese medicine compound is simple, without any additives, and has strong pharmacological compatibility. The anti-atherosclerotic application of the kidney-tonifying and turbidity-resolving traditional Chinese medicine compound includes: including observation cases, grouping, measuring the CIMT value and plaque area of ​​the included cases, data processing, and result analysis. This invention's kidney-tonifying and turbidity-resolving traditional Chinese medicine intervention can reduce the CIMT value and carotid plaque area in patients with atherosclerosis, and has a significant anti-atherosclerotic effect.
Owner:LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE

Traditional chinese medicine composition for treating membranous nephropathy, preparation method therefor, and use thereof

PCT designated stageWO2025175743A1Urinary disorderConiferophyta medical ingredientsCytoplasmic VacuolationAstragalus mongholicus
Provided are a traditional Chinese medicine composition for treating membranous nephropathy, a preparation method therefor, and use thereof. The traditional Chinese medicine composition comprises the following traditional Chinese medicine raw materials in parts by weight: 3-9 parts of Taxus chinensis, 9-12 parts of Curcuma zedoaria, 15-30 parts of Astragalus membranaceus, 6-12 parts of Panax notoginseng, and 10-20 parts of Gynostemma pentaphyllum. At the animal level, the traditional Chinese medicine composition can reduce proteinuria, regulate the lipid metabolism disorder, and protect the kidney. Furthermore, it is proved that the traditional Chinese medicine composition can alleviate the vacuolar degeneration of GBM or GBM thickening in experimental rats. Immunohistochemical analysis demonstrates that the formula can reduce the expression level of TGF-β1 in the renal interstitium, reduce the expression of ɑ-SMA and Col-IV collagen, reduce the deposition of ECM in the renal interstitium, and delay glomerulosclerosis and renal interstitial fibrosis.
Owner:SHANGHAI PUDONG NEW AREA PEOPLES HOSPITAL

Traditional Chinese medicine for treating type II diabetes

The invention discloses a traditional Chinese medicine for treating type II diabetes mellitus, which relates to the technical field of diabetes mellitus and comprises rhizoma polygonati, folium mori, bitter gourd, soybean, gynostemma pentaphyllum, astragalus membranaceus, ginseng and medlar. The patent medicine is prepared through the steps of medicine selecting, cleaning, drying, smashing, cell wall breaking, medicine filling, packaging and the like. The traditional Chinese medicine composition is specially used for treating type II diabetes mellitus, and by reasonably matching various Chinese herbal medicine components, the blood sugar level can be adjusted, and the symptoms of diabetics can be improved. All the raw materials in the formula are natural Chinese herbal medicines, and compared with chemical medicines, the traditional Chinese medicine composition is higher in safety and less in side effect. The components such as the rhizoma polygonati, the folium mori and the bitter gourd have the effect of reducing blood sugar, also possibly have various biological activities of regulating immunity, resisting oxidation, resisting inflammation and the like, and are beneficial to comprehensively improving the physique of a diabetic patient.
Owner:CHONGQING JINGKANGER SHOU HEALTH TECHNOLOGY CO LTD

A muscle stem cell resuscitation protection wash, quality assessment kit, and methods of use

This application discloses a muscle stem cell resuscitation and protection washing solution, a quality assessment kit, and a method of use, belonging to the field of cell biology technology. In this application, vitamin E succinate and mannan peptide are used as core antioxidant components, synergistically combined with Gynostemma pentaphyllum polysaccharide, Portulaca oleracea polysaccharide, trehalose, L-proline, and magnesium sulfate heptahydrate to construct a four-in-one resuscitation and protection washing solution that provides isotonic buffering, extracellular protection, intracellular protein stabilization, antioxidant effects, and mitochondrial stabilization. This increases the survival rate of muscle stem cells after resuscitation to over 93%. The kit integrates a multi-dimensional detection system for cell resuscitation and protection washing solution, cell viability, proliferation rate, Pax7 / MyoD double-positive stemness assessment, and cryopreservation damage, achieving closed-loop management of the entire process of muscle stem cell resuscitation, protection, and quality assessment. The double-positive rate of stemness markers reaches over 90%, providing reliable quality assurance for cell bank management and clinical applications.
Owner:JINAN WANQUAN BIOTECHNOLOGY CO LTD

Traditional Chinese medicine composition for preventing and treating tumor cancer and resisting relapse

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for preventing and treating tumor cancer and resisting relapse, which comprises the following raw materials in parts by weight: 1-50 parts of sanqi, 1-50 parts of Chinese mahonia, 10-100 parts of gynostemma pentaphylla, 1-50 parts of wild poria cocos, 1-50 parts of local scorpion and 1-60 parts of wild gastrodia elata. The whole formula is synergistic, and the cachexia metabolic disorder is improved by adjusting the intestinal flora-immune axis; the traditional Chinese medicine composition integrates three treatment methods of promoting blood circulation to remove blood stasis, clearing away heat and toxic materials and supporting healthy energy, eliminates evil without hurting healthy energy through multi-channel cross regulation and control, and provides a traditional Chinese medicine innovative scheme for tumor prevention and treatment.
Owner:HUNAN DURI TRADITIONAL CHINESE MEDICINE TECH DEV CO LTD

Traditional Chinese medicine composition for improving blood sugar and blood fat and preparation method thereof

PendingCN121243268AMetabolism disorderPill deliveryDANSHEN EXTRACTGINSENG EXTRACT
The invention discloses a traditional Chinese medicine composition for improving blood sugar and blood fat and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following components in percentage by mass: 10-22 parts of a ginseng extract, 10-50 parts of a gynostemma pentaphylla extract, 10-40 parts of a radix salviae miltiorrhizae extract and 10-40 parts of a fructus crataegi extract. The traditional Chinese medicine composition is simple in formula, simple and convenient to prepare, reliable in quality control, safe and effective, has double effects of improving blood sugar and blood fat, and has remarkable progress in the aspects of formula legality, raw material availability, process feasibility, quality controllability and efficacy comprehensiveness.
Owner:JING BRAND +1

Tea substitute drink beneficial to lowering lipid and relaxing bowels and preparation method of tea substitute drink

The invention discloses a tea substitute beverage beneficial to lowering lipid and relaxing bowels and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine preparations. The tea substitute beverage beneficial to lowering lipid and relaxing bowels comprises the following components in parts by mass: 4-8 parts of gynostemma pentaphyllum, 4-8 parts of fried semen cassiae, 2-5 parts of chrysanthemum, 2-5 parts of Chinese wolfberry, 1-3 parts of raw hawthorn, 1-3 parts of lophatherum gracile and 0.5-1 part of dendrobe. The fiveleaf gynostemma herb is subjected to enzymolysis; the fried semen cassiae is puffed fried semen cassiae. According to the present invention, the fiveleaf gynostemma herb, the fried cassia seed, the chrysanthemum, the Chinese wolfberry, the raw hawthorn, the lophatherum gracile and the dendrobium nobile are combined to prepare the tea substitute beverage beneficial to lipid lowering and bowel relaxing, the combined use of the traditional Chinese medicines can achieve the effects of lipid lowering, bowel relaxing and the like, and the tea substitute beverage beneficial to lipid lowering and bowel relaxing is strong in palatability, completely adopts the natural traditional Chinese medicinal materials, does not contain chemical additives, and is suitable for large-scale production. The long-term drinking safety is high; the tea bag is convenient to carry and brew and suitable for daily drinking.
Owner:山东医学高等专科学校

Agilawood moxibustion cigarette and manufacturing method thereof

The invention discloses an agilawood moxibustion cigarette and a manufacturing method thereof, and belongs to the field of cigarettes, the agilawood moxibustion cigarette comprises a paper cigarette tube, a filter tip and combustion filler, the combustion filler comprises agilawood leaves, lucid ganoderma, rhizoma polygonati, ginseng, anoectochilus formosanus, gynostemma pentaphylla, anoectochilus formosanus, phellinus igniarius, hedyotis diffusa, five-element tea, folium artemisiae argyi, folium eriobotryae and momordica grosvenori; the filter tip is a safe and environment-friendly filter tip made of degradable fibers, and the degradable fibers are more than one of cellulose acetate fibers, activated carbon fibers, bamboo fibers and straw fibers. According to a common smoking mode, smoke generated after combustion can be inhaled into the lung, nicotine is not contained, and the traditional Chinese medicine composition has the effects of clearing lung viscera, regulating intestines and stomach, discharging stubborn stool, strengthening yang, guiding qi downward, dissipating binds, ventilating the lung, clearing damp, expelling cold, discharging stasis and beautifying the face.
Owner:DONGGUAN ZHISHENGDE TRADING CO LTD

Traditional Chinese medicine preparation for treating stress urinary incontinence and preparation method thereof

The invention relates to a traditional Chinese medicine preparation for treating stress urinary incontinence, the traditional Chinese medicine preparation is prepared from rhizoma bletillae polysaccharide, asiaticoside, fructus cnidii essential oil, cinnamon essential oil and pharmaceutically acceptable auxiliary materials, and the pharmaceutically acceptable auxiliary materials comprise a gel matrix material, a humectant, a preservative, a pH regulator and a solvent. The rhizoma bletillae polysaccharide, the asiaticoside, the fructus cnidii essential oil and the cinnamon essential oil in the traditional Chinese medicine preparation are matched with one another, the excellent technical effect of synergistic interaction is achieved, the defect that the effect of treating stress urinary incontinence through a single active ingredient is limited is overcome, and the increasing treatment requirements of patients suffering from stress urinary incontinence can be met.
Owner:JIANGSU WEINA PHARM TECH CO LTD