91 results about "Gynostemma pentaphyllum" patented technology

The invention belongs to the technical field of biological medicines, and particularly discloses a composition with functions of reducing blood sugar and blood fat as well as a preparation method and application of the composition. Chinese herbal compound medicinal materials are subjected to water extraction and high-temperature and high-pressure sterilization, and lactobacillus rhamnosus SHA113 bacterial sludge is resuspended in a water extract to obtain the composition of lactobacillus rhamnosus SHA113 and the Chinese herbal compound; the traditional Chinese medicine compound composition comprises astragalus membranaceus, raw Chinese yam, hawthorn, gynostemma pentaphylla, liquorice and jujube; the preservation number of the lactobacillus rhamnosus SHA113 is CCTCC (China Center For Type Culture Collection) NO: M 2017838; the lactobacillus rhamnosus SHA113 and traditional Chinese medicine compound composition can remarkably reduce the content of triglyceride and cholesterol in serum, control the fasting blood-glucose level, relieve accumulation of triglyceride and cholesterol in the liver and improve the oxidation resistance of the liver, has wide market potential and application prospects, and has wide application prospects. The compound can be applied to preparation of drugs for reducing blood sugar and blood fat.

The invention discloses a pore cleaning mud mask and a preparation method thereof, belongs to the technical field of cosmetics, and particularly relates to a pore cleaning mud mask. Comprising 14 to 18 parts of kaolin, 7 to 9 parts of Manny root ice river mud, 4.5 to 5.5 parts of Amazon white mud, 10 to 12 parts of wheat germ oil, 43 to 47 parts of tea water, 0.1 to 0.14 part of a phellinus linteus extract, 1 to 2 parts of swertia mileensis powder, 2 to 4 parts of lactobionic acid, 0.08 to 0.12 part of salicylic acid and 0.4 to 0.6 part of gluconolactone. The pore cleaning mud mask provided by the invention is uniform in particle size distribution, uniform in mixing and capable of keeping the state of the mud mask moist and not dry in the use process, the cleaning strength of controlling oil, dredging pores and resisting inflammation is improved, meanwhile, skin sensitivity caused by excessive cleaning is avoided, and the cleaning effect is good. The invention provides a novel cleaning mud mask formula for realizing the goal of cleaning pores and an efficient and stable preparation method of the novel cleaning mud mask formula.

The invention discloses an oil-controlling, soothing and repairing composition and a preparation method thereof. The oil-controlling, soothing and repairing composition is prepared from a herba portulacae extract, a herba centellae extract, a baropetalum chinense leaf extract and a plankton extract. According to multiple experimental researches, the composition obtained by compounding the extracts has excellent effects of controlling oil, inhibiting activity of propionibacterium acnes, relieving and repairing, is mild and non-irritant, and has a good popularization and application prospect.

The invention discloses a roegneria ciliata PmRc1 gene, a protein coded by the roegneria ciliata PmRc1 gene and application of the roegneria ciliata The sequence of the powdery mildew resistance gene PmRc1 is derived from a small fragment translocation line TT-7 created by tetraploid roegneria ciliata and common wheat, the nucleotide sequence of the powdery mildew resistance gene PmRc1 is SEQ ID NO.1, and the amino acid sequence of the powdery mildew resistance gene PmRc1 is SEQ ID NO.2. The roegneria ciliata PmRc1 gene and the recombinant expression vector are applied to cultivation of wheat varieties with powdery mildew resistance. According to the candidate gene of the powdery mildew resistance gene PmRc1 derived from roegneria ciliata, the susceptibility can be enhanced by silencing the gene in a disease-resistant material, and the powdery mildew resistance can be improved by overexpressing the gene. The invention has important significance on wheat powdery mildew resistance breeding.

This invention provides a traditional Chinese medicine composition and its application in the preparation of a topical herbal eye patch for treating thyroid eye diseases, belonging to the field of biomedical technology. The herbal composition consists of *Gynostemma pentaphyllum*, peppermint, *Platycladus orientalis* leaves, borneol, cicada slough, *Astragalus membranaceus*, *Selaginella tamariscina*, *Pteris vittata*, *Scutellaria baicalensis*, apricot leaf, and *Ipomoea aquatica*. Using this herbal composition as raw material, a topical herbal eye patch is prepared. This patch acts directly on acupoints and skin around the eyes, allowing the medicinal properties to penetrate the skin and reach the eye system, achieving the effects of promoting blood circulation, clearing heat and detoxifying, invigorating qi and unblocking meridians, reducing swelling and improving vision. It is suitable for the treatment of thyroid-related eye diseases. This invention's topical herbal eye patch can effectively improve clinical symptoms such as exophthalmos and eye inflammation in patients with thyroid eye diseases, positively impacting their quality of life and effectively improving the clinical treatment efficacy of this disease. The topical herbal eye patch provided by this invention can be further promoted and applied in the clinical treatment of thyroid eye diseases.

The application discloses application of gynostemma pentaphyllum saponin H combined with azole drugs in preparation of antifungal drugs and the antifungal drugs, and relates to the technical field of antifungal drugs. It is found through systematic in-vitro drug sensitivity test that natural product gynostemma pentaphyllum saponin H combined with specific azole antifungal drugs (especially posaconazole POS) can produce significant synergistic antifungal effect, especially for clinical thorny aspergillus, candida, new cryptococcus and dark fungi. The combination strategy can significantly reduce the minimum inhibitory concentration of azole drugs, reverse drug resistance, and is effective for multi-drug resistant strains (such as candida auris). The application provides an efficient and low-toxicity new combination drug scheme for overcoming the increasingly serious fungal drug resistance problem.

The invention discloses a traditional Chinese medicine fumigation bag for relieving eye fatigue and a preparation method and application thereof, and belongs to the technical field of eye medicine. The traditional Chinese medicine fumigation bag for relieving eye fatigue is prepared from the following components in parts by weight: 10 to 30 parts of flos chrysanthemi indici, 10 to 30 parts of frosted folium mori, 10 to 30 parts of semen cassiae, 10 to 30 parts of herba gynostemmatis pentaphylli, 5 to 20 parts of herba menthae, 5 to 20 parts of folium perillae and 5 to 20 parts of herba dendrobii. According to the traditional Chinese medicine fumigation bag, through formula design, a slow release technology and a double-layer packaging technology, the defects that in the prior art, the medicine effect is short, and components are prone to losing are overcome, and the effect of a traditional fumigation therapy method is remarkably improved.

The invention belongs to the field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition and a preparation and application thereof. A compatibility system of monarch, minister, assistant and guide is adopted, rhizoma atractylodis, semen coicis and cortex phellodendri are taken as monarch drugs, polygonum cuspidatum, centella asiatica and fructus kochiae are taken as minister drugs, prepared rheum officinale, radix achyranthis bidentatae and caulis spatholobi are taken as guide drugs, gynostemma pentaphyllum, radix paeoniae alba and rhizoma polygonati are taken as adjuvant drugs, the medicinal materials are compounded according to a specific mass ratio, and the mass ratio of the monarch drugs to the minister drugs to the adjuvant drugs to the guide drugs is (50-80): (50-80): (30-55): (35-70). The traditional Chinese medicine composition provided by the invention can remarkably reduce the levels of blood uric acid, serum creatinine and urea nitrogen, reduce urine protein excretion and improve inflammation, a hypercoagulation state and lipid metabolism disorder, the total effective rate reaches 90%, the adverse reaction is slight, and the recurrence rate is low.

This invention relates to the field of health products or food technology, and more specifically to a composition and its application in removing dampness and controlling blood sugar, balancing blood pressure, and regulating blood lipids. The invention provides a composition for removing dampness and controlling blood sugar, balancing blood pressure, and regulating blood lipids, comprising Poria cocos extract, Astragalus membranaceus extract, hirudin, and at least one or more of Eucommia ulmoides extract, Gynostemma pentaphyllum extract, and Morus alba twig extract. The composition provided by this invention utilizes extracts from at least four precious Chinese medicinal herbs to exert a synergistic effect, jointly achieving the effects of lowering blood pressure, removing dampness and lowering blood sugar, and lowering blood lipids.

This invention provides a traditional Chinese medicine compound for treating viral myocarditis, belonging to the field of traditional Chinese medicine pharmaceutical technology. The compound consists of Forsythia suspensa, Fagopyrum dibotrys, Pseudostellaria heterophylla, Rhodiola rosea, Citrus medica, Allium macrostemon, Poria cocos, Gynostemma pentaphyllum, Salvia miltiorrhiza, Dalbergia odorifera, Cynanchum paniculatum, and Valeriana. This traditional Chinese medicine compound exhibits significant protective effects against viral myocarditis, specifically by significantly reducing damage to H9c2 cardiomyocytes caused by CVB3 virus. Its mechanism of action is closely related to downregulating the expression of inflammatory factors TNF-α and IL-6 and inhibiting the inflammatory response. Simultaneously, within the experimental concentration range, the compound shows no toxicity to cardiomyocytes, demonstrating good biocompatibility. Furthermore, this compound can significantly reduce myocardial tissue damage in a viral myocarditis model mouse by inhibiting the in vivo inflammatory response and regulating oxidative stress imbalance, providing a safe and effective new treatment option for the clinical treatment of viral myocarditis.

The invention discloses a traditional Chinese medicine formula (Shenhuang decoction) for treating postoperative wounds of high-order perianal abscess, belongs to the field of traditional Chinese medicines, and aims to solve the problems of wound infection, slow healing and obvious pain and edema after the high-order perianal abscess. The formula is based on 30 g of radix sophorae flavescentis, 20 g of cortex phellodendri, 15 g of radix angelicae, 6 g of radix arnebiae seu lithospermi, 15 g of frankincense, 15 g of radix angelicae sinensis, 10 g of rhizoma bletillae, 10 g of resina draconis and 3 g of borneol, and increase and decrease are carried out according to symptoms: when swelling is obvious, peach kernels and spina gleditsiae (leeches and earthworms are added, when secretion is more, astragalus membranaceus is reinforced, when bleeding occurs, pseudo-ginseng and hairyvein agrimony are added, honeysuckle stems are added when heat is excessive, and when the mouth is not closed for a long time, codonopsis pilosula, rhodiola rosea, gynostemma pentaphyllum and gallnut are added. The preparation adopts an ultrasonic atomization liquid form, is prepared by decocting with water and taking 400ml of juice (at 38 DEG C), and is atomized, fumigated and washed for 15 minutes once in the morning and once in the evening every day, and is matched with conventional dressing change. The traditional Chinese medicine composition can clear away heat and toxic materials, promote blood circulation to arrest pain, remove slough and promote granulation, reduce the level of TNF-alpha and IL-6, shorten the wound healing time and relieve pain and edema, and is suitable for wound recovery after high perianal abscess operation.

The invention relates to the technical field of pharmaceutical preparations, in particular to a myocardial protection traditional Chinese medicine composition capable of clearing heat, promoting blood circulation and removing blood stasis, a preparation and a preparation method and application of the myocardial protection traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following medicinal materials in parts by weight: 5-15 parts of gentiana acuminata, 10-20 parts of salvia miltiorrhiza, 5-15 parts of angelica sinensis, 10-20 parts of gynostemma pentaphylla, 5-15 parts of rhodiola rosea, 3-10 parts of hematoxylon, 5-15 parts of radix paeoniae rubra, 3-10 parts of lumbricus, 3-10 parts of radix curcumae, 10-20 parts of astragalus membranaceus, 3-10 parts of ginseng, 5-15 parts of radix ophiopogonis, 3-8 parts of schisandra chinensis and 3-8 parts of liquorice. According to the traditional Chinese medicine compound provided by the invention, through the synergistic effect of clearing heat, promoting blood circulation, removing blood stasis, tonifying qi and nourishing yin, the synergistic effect can be achieved more comprehensively aiming at the pathogenesis of heat-blood stasis intermingling. The traditional Chinese medicine composition has remarkable advantages in the aspect of treating myocardial ischemia reperfusion injury, the curative effect of the traditional Chinese medicine composition depends on complete monarch, minister, assistant and guide compatibility, and the overall medicine effect can be reduced if part of components are lost.

The application provides a preparation process of tea of fructus phoebe and a tea beverage containing the tea of fructus phoebe. The preparation process of the tea of fructus phoebe comprises the following steps: S1, taking fresh tea leaves of fructus phoebe, drying, crushing, passing through a 40-100 mesh sieve and adding water; S2, adding a compound enzyme for enzymolysis; S3, deactivating the enzyme, filtering and obtaining an extract containing the tea of fructus phoebe. Through compounding ingredients such as gynostemma pentaphyllum and fat sea cucumber, the tea beverage has high stability, good taste and high content of bioactive components, and has wide application value and market prospect.

This invention belongs to the field of traditional Chinese medicine technology, and discloses a kidney-tonifying and turbidity-resolving traditional Chinese medicine compound, its preparation method, and its anti-atherosclerotic application. The effective components of the kidney-tonifying and turbidity-resolving traditional Chinese medicine compound, by mass, consist of 15 parts Rehmannia glutinosa (processed), 15 parts Astragalus membranaceus (raw), 9 parts Cistanche deserticola, 10 parts Nelumbo nucifera (lotus leaf), 20 parts Gynostemma pentaphyllum, 12 parts Crataegus pinnatifida, and 6 parts Citrus reticulata (dried tangerine peel). The preparation method of the kidney-tonifying and turbidity-resolving traditional Chinese medicine compound is simple, without any additives, and has strong pharmacological compatibility. The anti-atherosclerotic application of the kidney-tonifying and turbidity-resolving traditional Chinese medicine compound includes: including observation cases, grouping, measuring the CIMT value and plaque area of ​​the included cases, data processing, and result analysis. This invention's kidney-tonifying and turbidity-resolving traditional Chinese medicine intervention can reduce the CIMT value and carotid plaque area in patients with atherosclerosis, and has a significant anti-atherosclerotic effect.

This application discloses a muscle stem cell resuscitation and protection washing solution, a quality assessment kit, and a method of use, belonging to the field of cell biology technology. In this application, vitamin E succinate and mannan peptide are used as core antioxidant components, synergistically combined with Gynostemma pentaphyllum polysaccharide, Portulaca oleracea polysaccharide, trehalose, L-proline, and magnesium sulfate heptahydrate to construct a four-in-one resuscitation and protection washing solution that provides isotonic buffering, extracellular protection, intracellular protein stabilization, antioxidant effects, and mitochondrial stabilization. This increases the survival rate of muscle stem cells after resuscitation to over 93%. The kit integrates a multi-dimensional detection system for cell resuscitation and protection washing solution, cell viability, proliferation rate, Pax7 / MyoD double-positive stemness assessment, and cryopreservation damage, achieving closed-loop management of the entire process of muscle stem cell resuscitation, protection, and quality assessment. The double-positive rate of stemness markers reaches over 90%, providing reliable quality assurance for cell bank management and clinical applications.

The invention discloses a traditional Chinese medicine composition for improving blood sugar and blood fat and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following components in percentage by mass: 10-22 parts of a ginseng extract, 10-50 parts of a gynostemma pentaphylla extract, 10-40 parts of a radix salviae miltiorrhizae extract and 10-40 parts of a fructus crataegi extract. The traditional Chinese medicine composition is simple in formula, simple and convenient to prepare, reliable in quality control, safe and effective, has double effects of improving blood sugar and blood fat, and has remarkable progress in the aspects of formula legality, raw material availability, process feasibility, quality controllability and efficacy comprehensiveness.

The invention discloses an agilawood moxibustion cigarette and a manufacturing method thereof, and belongs to the field of cigarettes, the agilawood moxibustion cigarette comprises a paper cigarette tube, a filter tip and combustion filler, the combustion filler comprises agilawood leaves, lucid ganoderma, rhizoma polygonati, ginseng, anoectochilus formosanus, gynostemma pentaphylla, anoectochilus formosanus, phellinus igniarius, hedyotis diffusa, five-element tea, folium artemisiae argyi, folium eriobotryae and momordica grosvenori; the filter tip is a safe and environment-friendly filter tip made of degradable fibers, and the degradable fibers are more than one of cellulose acetate fibers, activated carbon fibers, bamboo fibers and straw fibers. According to a common smoking mode, smoke generated after combustion can be inhaled into the lung, nicotine is not contained, and the traditional Chinese medicine composition has the effects of clearing lung viscera, regulating intestines and stomach, discharging stubborn stool, strengthening yang, guiding qi downward, dissipating binds, ventilating the lung, clearing damp, expelling cold, discharging stasis and beautifying the face.

The invention relates to a traditional Chinese medicine preparation for treating stress urinary incontinence, the traditional Chinese medicine preparation is prepared from rhizoma bletillae polysaccharide, asiaticoside, fructus cnidii essential oil, cinnamon essential oil and pharmaceutically acceptable auxiliary materials, and the pharmaceutically acceptable auxiliary materials comprise a gel matrix material, a humectant, a preservative, a pH regulator and a solvent. The rhizoma bletillae polysaccharide, the asiaticoside, the fructus cnidii essential oil and the cinnamon essential oil in the traditional Chinese medicine preparation are matched with one another, the excellent technical effect of synergistic interaction is achieved, the defect that the effect of treating stress urinary incontinence through a single active ingredient is limited is overcome, and the increasing treatment requirements of patients suffering from stress urinary incontinence can be met.

This invention relates to a multi-effect synergistic lipid-lowering composition for food and its preparation method, belonging to the field of food technology. The composition includes the following raw materials: a compound fermentation broth, *Gynostemma pentaphyllum* extract, *Lycium chinense* root bark extract, and *Rosa rugosa* fruit extract. In the preparation of the compound fermentation broth, *Rosa laevigata*, mulberry twigs, and *Fritillaria cirrhosa* are co-fermented with a compound microbial culture consisting of *Pediococcus pentosaceus*, *Lactobacillus curvatureii*, and *Kluyveromyces lactis*. This fully utilizes the synergistic effects of the raw materials and the advantages of the fermentation process, further enhancing the antioxidant activity of the multi-effect synergistic lipid-lowering composition. Furthermore, this invention also uses *Gynostemma pentaphyllum*, *Lycium chinense* root bark, and *Rosa rugosa* fruit as raw materials to prepare extracts, which are then compounded as components of the multi-effect synergistic lipid-lowering composition. This effectively utilizes the lipid-lowering properties of different raw materials, synergistically enhancing their effects to achieve lipid-lowering and weight-loss effects.

The present application relates to the construction method of Gengnining HPLC fingerprint and its application, which can comprehensively evaluate and control the quality of Gengnining, is beneficial to stabilize the product quality, ensure the stability and uniformity of its inherent quality, ensure the safety and effectiveness of clinical medication, and the technical solution thereof is that the construction method of Gengnining HPLC fingerprint comprises the following steps: 1) preparation of reference solution; 2) preparation of medicinal material solution; 3) preparation of test sample solution; 4) determination of HPLC chromatographic conditions; 5) calculation and determination of the relative retention time and the ratio of relative peak area of 9 main characteristic peaks with large peak area; the method is simple, fast, reproducible, stable, and through the comparison of characteristic peaks in the standard fingerprint, the quality of Gengnining can be comprehensively evaluated and controlled, which is beneficial to stabilize the product quality, ensure the stability and uniformity of its inherent quality, ensure the safety and effectiveness of clinical medication, and is an innovation in the quality detection method of Gengnining product.

This invention relates to a decoction process and equipment for treating non-alcoholic fatty liver disease (NAFLD). The raw materials of the decoction, by weight, are: 15 parts Artemisia capillaris, 10 parts Gardenia jasminoides, 10 parts Crataegus pinnatifida, 10 parts Bupleurum chinense, 15 parts stir-fried Paeonia lactiflora, 10 parts Citrus aurantium, 5 parts Glycyrrhiza uralensis, 10 parts Nelumbo nucifera, 15 parts Cassia tora, 10 parts Gynostemma pentaphyllum, 30 parts Benincasa hispida peel, 15 parts Salvia miltiorrhiza, and 9 parts Atractylodes lancea. The equipment includes a decoction container and a container lid. A connecting column is provided on the lower surface of the container lid. A first medicine-carrying mesh tray is fixed at the bottom of the connecting column. A second medicine-carrying mesh tray is longitudinally hinged to each side of the first medicine-carrying mesh tray. A rotating sleeve is provided on the upper part of the connecting column. The rotating sleeve is connected to the outer side of the second medicine-carrying mesh tray through multiple stainless steel ropes. This invention transforms the traditional wisdom of batch decoction in traditional Chinese medicine into a standard process that can be executed by modern automated equipment, and provides a standardized decoction solution for the treatment of NAFLD with traditional Chinese medicine that is more effective, safer to use, and easier to operate.

The invention discloses a traditional Chinese medicine composition for treating precancerous lesions of pulmonary nodules and a preparation method of the traditional Chinese medicine composition. The composition is prepared from 30 parts of coix seeds, 15 parts of astragalus membranaceus, 30 parts of pyrrosia lingua, 10 parts of raw rhizoma atractylodis macrocephalae, 10 parts of fried hawthorn, 10 parts of folium isatidis, 30 parts of oysters, 15 parts of caulis spatholobi, 30 parts of oldenlandia diffusa, 10 parts of fructus lycii, 10 parts of glossy privet fruits, 15 parts of radix glehniae, 3 parts of gecko, 6 parts of liquorice, 15 parts of codonopsis pilosula, 6 parts of cassia twigs, 30 parts of salvia chinensis, 15 parts of Chinese waxgourd seeds, 10 parts of verbena and 10 parts of asparagus cochinchinensis. During preparation, the medicinal materials are selected and crushed, and refined honey is added to prepare pills. Clinical research shows that after the preparation is taken for 6 months, the maximum diameter of pulmonary nodules of a patient is remarkably reduced, the malignant probability of mei-ovum is reduced from 16.60% to 8.33%, the integral of traditional Chinese medicine syndromes is reduced from 10.91 to 6.91, and the serum CEA is reduced from 2.0 ng / mL to 1.51 ng / mL. The traditional Chinese medicine composition has the effects of tonifying qi and yin, reducing phlegm, removing toxins and eliminating diseases aiming at the lung nodule precancerous lesion with the syndrome of vital qi deficiency and phlegm stagnation, and is definite in curative effect and high in safety.

The invention belongs to the technical field of poultry breeding, and particularly relates to a traditional Chinese veterinary medicine for accelerating recovery of feed intake of poultry after illness, the traditional Chinese veterinary medicine is prepared from the following raw medicinal materials in parts by weight: 10-26 parts of rice sprout, 10-26 parts of gynostemma pentaphylla, 5-15 parts of tuber fleeceflower stem, 10-22 parts of radix bupleuri, 5-15 parts of radix aconiti carmichaeli, 10-35 parts of galangal, 10-22 parts of andrographis paniculata and 5-16 parts of liquorice. According to the traditional Chinese veterinary medicine for accelerating the recovery of the feed intake of the poultry after the disease and the preparation method of the traditional Chinese veterinary medicine, the rice sprout, the gynostemma pentaphylla, the tuber fleeceflower stem, the radix bupleuri, the radix aconiti carmichaeli, the rhizoma galangae, the herba andrographitis and the liquorice are added, and a plurality of Chinese herbal medicine raw medicinal materials are combined according to a proposed proportion and can complement each other and have a synergistic effect, so that the respective medicinal effects are exerted to the maximum extent; the multiple medicinal materials are mixed to achieve a synergistic effect, the spleen, stomach, heart and kidney functions of the poultry are comprehensively conditioned, the recovery efficiency of food consumption after diseases is further improved, and compared with chemical medicines, traditional Chinese veterinary medicines have the advantages of being small in side effect, few in residue and the like by selecting traditional Chinese medicines to be mixed and matched with the chemical medicines.

The invention discloses a traditional Chinese medicine compound extract as well as an extraction method and application thereof, and relates to the technical field of modern extraction and preparations of traditional Chinese medicines, the traditional Chinese medicine compound extract is prepared from a core medicine group, a synergistic component, a targeted strengthening component and preparation auxiliary materials in parts by weight: the core medicine group comprises 12-25 parts of ginseng under forest, 18-35 parts of radix ophiopogonis from Sichuan of China and 10-20 parts of fructus schisandrae; the synergistic components comprise 8-20 parts of dendrobium officinale, 5-15 parts of gynostemma pentaphylla and 3-10 parts of perilla leaves; a targeting strengthening component: 1-4 parts of a glutathione-selenium compound; according to the method, fat-soluble components are extracted through ultrasonic-microwave synergy, water-soluble polysaccharide is extracted through the enzymolysis coupling dynamic high-pressure microjet technology, and volatile active components are captured in combination with the vacuum low-temperature molecular distillation technology. The problems of component loss and degradation caused by a traditional single extraction method are solved, the extraction rate of core functional components such as ginsenoside, ophiopogon japonicus polysaccharide, dendrobium polysaccharide and schizandrin A is remarkably increased, and richness and integrity of chemical components of the extract are ensured.

The invention discloses a device and a process for extracting polysaccharides of female endophytic fungi of canarium album for immune mechanism research, and the device comprises a pretreatment unit which is used for carrying out ultrasonication on mycelia of the cultured and activated female endophytic fungi of canarium album; the extraction unit is located at the next station of the pretreatment unit, and the extraction unit adopts a hot water extraction device to carry out constant-temperature water bath on the mycelium; the emulsifying unit is located at the next station of the extracting unit, and the emulsifying unit is used for removing protein in the extracting solution through emulsifying centrifugation; the precipitation unit is positioned at the next station of the emulsification unit and is used for oxidizing and decoloring the extracting solution and then carrying out low-temperature precipitation, and then carrying out desalination and impurity removal on the precipitate and then carrying out drying treatment; according to the method, the broken mycelium polysaccharide is extracted and purified in a hot water extraction mode, the activity of the polysaccharide can be well kept, the active polysaccharide is enriched and concentrated, the method is mild in condition, and damage to glucosidic bonds and advanced space structures of the polysaccharide due to use of strong acid, strong alkali or organic solvents is avoided.

The application belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating ovarian cancer, a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw medicinal materials: Astragalus membranaceus (Fisch.) Bunge, Ramulus Cinnamomi, Poria cocos (Schw.) Wolf, Semen Persicae, Gynostemma pentaphyllum (Thunb.) Makino, Radix Moutan, Magnolia officinalis Rehd. et Wils., and Hirudo nipponia Whitfield. The traditional Chinese medicine composition has the effects of benefiting qi and activating blood, removing blood stasis and dredging collaterals. Therefore, the traditional Chinese medicine composition is suitable for patients after surgery or radiotherapy and chemotherapy for ovarian cancer, and is also suitable for patients who cannot tolerate surgery or radiotherapy due to poor physical condition. The traditional Chinese medicine composition has the effects of reducing tumor cell proliferation, regulating tumor immunity, reducing toxicity and increasing efficacy. In the maintenance treatment stage, the traditional Chinese medicine composition can enhance the immunity of patients, prolong the survival period of patients, and improve the life quality of patients.

The invention discloses a traditional Chinese medicine ointment for improving pancreas islet function and a preparation method and application thereof. The traditional Chinese medicine ointment is prepared from ginseng, astragalus membranaceus, radix ophiopogonis, salvia miltiorrhiza, corn stigma, radix polygonati officinalis, radices trichosanthis, dandelion root, Chinese yam, poria cocos, radix puerariae, purslane, potentilla discolor, cyclocarya paliurus, folium mori, liquorice, momordica grosvenori, radix rehmanniae recen, coptis chinensis, chrysanthemum, honeysuckle, buckwheat, rhizoma anemarrhenae, cinnamon, bitter gourd, gynostemma pentaphyllum, cortex lycii radicis, rhizoma phragmitis and the like according to a specific weight part ratio. The invention further provides a preparation method of the traditional Chinese medicine ointment. The preparation method comprises the steps of soaking in water, decocting and extracting, filtering and concentrating, ointment collecting and the like. The traditional Chinese medicine ointment can remarkably reduce fasting blood glucose and postprandial blood glucose of diabetic model mice and improve abnormal glucose tolerance, and has a protection effect on pancreas islet tissues. The traditional Chinese medicine ointment can be used for preparing health care products for assisting in reducing blood sugar or pharmaceutical compositions for preventing and assisting in treating type 2 diabetes mellitus, and has the advantages of reasonable formula, exact curative effect, stable preparation process and the like.

This invention provides a traditional Chinese medicine preparation for treating liver cancer, belonging to the field of traditional Chinese medicine pharmaceutical technology. The preparation is made from five-finger peach, *Euphorbia helioscopia*, *Lysimachia christinae*, *Typha orientalis*, *Gentiana macrophylla*, *Eucommia ulmoides*, *Bitter orange blossom*, *Gynostemma pentaphyllum*, *Gynostemma pentaphyllum*, and jujube. Five-finger peach and *Euphorbia helioscopia* are the principal herbs; *Lysimachia christinae*, *Typha orientalis*, *Gentiana macrophylla*, and *Gentiana macrophylla* are the assistant herbs; *Bitter orange blossom*, *Gynostemma pentaphyllum*, *Gynostemma pentaphyllum*, and *Eucommia ulmoides* are the adjuvant herbs; and jujube is the guiding herb. The combination of these herbs is rational, balancing the strengthening of the body's resistance with the elimination of pathogenic factors, achieving the effects of tonifying qi and strengthening the body's resistance, resolving blood stasis and detoxifying, clearing heat and promoting diuresis, and soothing the liver and regulating qi. This traditional Chinese medicine preparation significantly inhibits the proliferation, migration, and invasion of liver cancer cells, effectively reduces tumor volume and weight in tumor-bearing mice, slows tumor growth, and effectively improves immune organ indices and immune cytokines in tumor-bearing mice, exhibiting an immune-enhancing effect. This traditional Chinese medicine preparation shows promise as a new option for treating liver cancer.