Traditional Chinese medicine composition for treating abdominal obesity and preparation method thereof

Abstract

The invention belongs to the technical field of traditional Chinese medicine compositions, and particularly relates to a traditional Chinese medicine composition for treating abdominal obesity and a preparation method thereof, and the traditional Chinese medicine composition comprises the following raw materials: corn stigma, coix seeds, radish seeds, hawthorn, lotus leaves, poria cocos, rhizoma alismatis and phaseolus calcaratus which are taken as a basic formula. The traditional Chinese medicine composition for treating hard abdomen type obesity, the traditional Chinese medicine composition for treating soft abdomen type obesity and the traditional Chinese medicine composition for treating neutral obesity all comprise basic formulas. The raw materials of the traditional Chinese medicine composition for treating hard abdomen obesity further comprise rhubarb processed with vinegar, fiveleaf gynostemma herb, officinal magnolia bark, cassia seed, virgate wormwood herb, motherwort herb, common selfheal fruit-spike and thunberg fritillary bulb. The traditional Chinese medicine composition for treating soft abdomen type obesity further comprises the following raw materials: herba lycopi, semen plantaginis, radix astragali, rhizoma atractylodis macrocephalae, orange peel and rhizoma atractylodis. The traditional Chinese medicine composition for treating neutral obesity further comprises the following raw materials: rhubarb processed with vinegar, fiveleaf gynostemma herb, officinal magnolia bark, cassia seed, virgate wormwood herb, motherwort herb, hiraute shiny bugleweed herb, plantain seed, milkvetch root, largehead atractylodes rhizome, orange peel, swordlike atractylodes rhizome, common selfheal fruit- The invention discloses three traditional Chinese medicine compositions for treating abdominal obesity, corresponding different traditional Chinese medicine compositions can be selected according to different clinical manifestations and abdominal palpation resistance (elasticity) and hardness, diagnosis and treatment are simple and practical, and popularization and application are convenient.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicine compositions, and particularly to a traditional Chinese medicine composition for treating abdominal obesity and a preparation method thereof. Background Art

[0002] Western medicine believes that obesity refers to excessive accumulation of body fat and / or abnormal distribution, and is a common metabolic disease. The body mass index (BMI) is commonly used to evaluate obesity. Body mass index (BMI) = weight (kg) / square of height (m). If the body mass index exceeds 24, it is overweight; if it exceeds 28, it is obese; if it is between 24 and 28, it is overweight. According to the etiology, it is divided into two major categories: simple obesity and secondary obesity. Western medicine weight loss drugs include fenfluramine, but it has been banned due to its large side effects. Orlistat achieves weight loss by reducing fat absorption, but it can affect the absorption of fat-soluble vitamins and cause gastrointestinal symptoms such as abdominal pain, diarrhea, loss of appetite, and even jaundice. Obesity rebounds quickly after stopping the drug. Semaglutide injection was originally used for adult patients with type 2 diabetes to control blood sugar, and now it is also used for obese patients, but its side effects include hypoglycemic reactions, nausea, vomiting, and diarrhea gastrointestinal reactions, and a small number of cases also have acute pancreatitis.

[0003] Traditional Chinese medicine has a long history of understanding obesity, which is called "fat people", "greasy people", "fatty people", etc. Regarding the etiology, it is considered that there are differences in constitution and endowment, improper diet, preference for quietness and aversion to movement, seven emotions and staying up late, etc. Regarding the pathogenesis, there are multiple aspects such as "phlegm-dampness", "stomach heat", "spleen deficiency", "qi deficiency", "blood stasis", "yang deficiency", "liver depression", etc. The syndrome type classification is diverse, with more than ten types at most and four or five types at least, which is very messy, and so far, no unified classification and unified treatment plan have been formed. In terms of Chinese patent medicines, there are products such as Jiangzhi Jianfei Tablets, Qingshen Jianfei Tablets, Paidu Qingzhi Capsules, Qingshen Xiaopang Pills, etc., but the varieties are few and the classification is incomplete. In terms of curative effects, some are effective and some are ineffective, and the effective rate is not high, all of which are not satisfactory. The main reason is that the etiology and pathogenesis of obesity are complex, the syndrome type classification is messy and complicated, and the syndrome types are mutually inclusive, and no weight loss drug can target multiple etiologies and pathogenesis, so the curative effect is not high.

[0004] Diseases can be divided into exogenous and endogenous ones. Obesity should belong to endogenous diseases, not exogenous ones. Improper diet, emotional disorders, staying up late and fatigue are common pathogenic factors, which can lead to abnormal functions of the spleen and stomach, especially the impairment of the transportation and transformation function of the spleen, that is, so-called spleen deficiency, thus affecting fat metabolism and further resulting in abnormal distribution and accumulation of fat. The most obvious part is the abdomen, and others include the buttocks, face, waist, back, shoulders and limbs. However, there is a very special phenomenon that has not been noticed by anyone so far, that is, for the same obesity, some people's abdomens feel hard when touched, with a strong sense of resistance, while some people's abdomens feel very soft, even with fat sagging, lacking elasticity and having a weak sense of resistance. Here, it is necessary to clarify the three concepts of hard-abdomen obesity, soft-abdomen obesity and neutral obesity first.

[0005] (1) Hard-abdomen obesity: When the examinee (obese person) is in a fasting, lying flat and natural relaxation state, the examiner presses the abdomen of the examinee with about 5 kilograms of thrust with one hand. If the examiner's hand can obviously feel a strong sense of resistance (elasticity) and feels that the examinee's abdomen is hard, with a feeling of stiffness. This kind of obesity is called hard-abdomen obesity.

[0006] (2) Soft-abdomen obesity: When the examinee (obese person) is in a fasting, lying flat and natural relaxation state, the examiner presses the abdomen of the examinee with about 5 kilograms of thrust with one hand. The examiner's hand feels that the sense of resistance (elasticity) is not strong, relatively weak, and feels that the examinee's abdomen is soft, and even the subcutaneous fat can be seen to be loose and sagging. This kind of obesity is called soft-abdomen obesity.

[0007] (3) Neutral obesity: When the examinee (obese person) is in a fasting, lying flat and natural relaxation state, the examiner presses the abdomen of the examinee with about 5 kilograms of thrust with one hand. The examiner's hand feels that the sense of resistance (elasticity) is moderate, neither strong nor weak, and feels that the examinee's abdomen is neither hard nor soft, in an intermediate state between hard-abdomen obesity and soft-abdomen obesity. This kind of obesity is called neutral obesity.

[0008] Traditional Chinese medicine believes that the spleen is in charge of transportation and transformation, is the source of qi and blood generation, and is also an important organ for transforming dampness and removing turbidity. Improper diet, fatigue from staying up late, and disharmony of the seven emotions can all lead to weakness of the spleen and stomach, decline of the transportation and transformation functions, thus generating phlegm-dampness stasis and turbidity, which further transform into fat and cream, stagnating in the muscles, skin and meridians, resulting in local fat accumulation. Therefore, fat distribution can be seen on the abdomen, buttocks, face, chest, waist, back and limbs on the outside. So obesity is based on spleen deficiency and marked by phlegm-dampness stasis and turbidity. However, any disease has three states in terms of disease nature: cold type, heat type, and cold-heat complex type. Similarly, obesity also needs to be distinguished into these three states. Through long-term in-depth research by the inventor, it is found that hard-abdomen obesity belongs to the heat type, that is, spleen deficiency with phlegm-dampness stasis and turbidity heat type; soft-abdomen obesity belongs to the cold type, that is, spleen deficiency with phlegm-dampness stasis and turbidity cold type; neutral obesity belongs to the cold-heat complex type, that is, spleen deficiency with phlegm-dampness stasis and turbidity cold-heat complex type. At the same time, it is found that these three types also have their respective clinical characteristics and treatment characteristics.

[0009] (1) In addition to obesity, abdominal obesity with a hard abdomen may be accompanied by the following clinical manifestations: relatively young age, good appetite, dry mouth and bitter taste, bad breath, normal stools or constipation or sticky stools, yellow or cloudy urine, a relatively hard abdomen upon palpation, a strong sense of resistance, and in women, scanty and dark menstrual flow, red tongue, yellow and greasy tongue coating, slippery and rapid pulse, etc.

[0010] (2) In addition to obesity, abdominal obesity with a soft abdomen may be accompanied by the following clinical manifestations: relatively older age, normal or little food intake, drowsiness and fatigue, aggravated fatigue upon movement, even shortness of breath, preferring quietness to movement, normal or loose stools, clear or foamy urine. The subcutaneous fat in the abdomen is loose or even sagging, soft upon palpation, with a weak sense of resistance. In women, there may be scanty or irregular menstrual flow, dark color. The tongue is pale, red and enlarged, with tooth marks on the sides, white and greasy or slippery and greasy tongue coating, deep and weak pulse, etc.

[0011] (3) In addition to obesity, neutral abdominal obesity may be accompanied by the following clinical manifestations: normal diet, no obvious dry mouth and bitter taste, sometimes feeling fatigued, normal or sticky stools, normal or yellow urine. The abdomen upon palpation is neither soft nor hard, with a moderate sense of resistance. In women, there may be scanty and dark menstrual flow. The tongue is pale red, with a white or yellow and greasy or thick and greasy tongue coating, and there may be tooth marks on the sides of the tongue, deep pulse, etc.

[0012] The inventor of the present invention first proposed that obesity can be simply divided into three types through abdominal palpation: abdominal obesity with a hard abdomen, abdominal obesity with a soft abdomen, and neutral abdominal obesity. At the same time, the treatment is also divided into three corresponding types, that is, for abdominal obesity with a hard abdomen, a traditional Chinese medicine composition for treating abdominal obesity with a hard abdomen is used; for abdominal obesity with a soft abdomen, a traditional Chinese medicine composition for treating abdominal obesity with a soft abdomen is used; and for neutral abdominal obesity, a traditional Chinese medicine composition for treating neutral abdominal obesity is used.

[0013] However, no one has yet used such a simple and practical classification method and treatment measures for obesity, and the raw materials used are all raw materials that are both medicine and food. People have been trying to use a single prescription to solve the problem of obesity, but in fact, there are differences in abdominal obesity with a hard abdomen, abdominal obesity with a soft abdomen, and neutral abdominal obesity. Therefore, the current weight loss drugs are not targeted enough, some are effective, some are ineffective, the curative effects are not high, and they are prone to rebound.

[0014] In view of this, the present invention is proposed. Summary of the Invention

[0015] (1) Technical problems to be solved

[0016] In view of the above problems of the prior art, the object of the present invention is to provide a traditional Chinese medicine composition for treating abdominal obesity and its preparation method, which selects different collocation methods of traditional Chinese medicine compositions according to different basic syndromes, is simple and practical, and is convenient for popularization and application.

[0017] (2) Technical solutions

[0018] To achieve the above object, the present invention provides the following technical solution: A traditional Chinese medicine composition for treating abdominal obesity and its preparation method, comprising the following raw materials: corn silk, coix seed, radish seed, hawthorn, lotus leaf, poria cocos, alisma orientale, adzuki bean. The combination of these eight raw materials is called the basic formula by the inventor. The raw materials in the traditional Chinese medicine composition for treating hard abdominal obesity, the traditional Chinese medicine composition for treating soft abdominal obesity, and the traditional Chinese medicine composition for treating neutral obesity all contain the raw materials in the basic formula.

[0019] The raw materials of the traditional Chinese medicine composition for treating hard abdominal obesity further include, on the basis of the basic formula: rhubarb processed with vinegar, gynostemma pentaphyllum, magnolia officinalis, cassia seed, artemisia capillaris, motherwort, prunella vulgaris, fritillaria thunbergii.

[0020] The raw materials of the traditional Chinese medicine composition for treating soft abdominal obesity further include, on the basis of the basic formula: lycopus lucidus, plantago asiatica, astragalus membranaceus, atractylodes macrocephala, citrus reticulata peel, atractylodes lancea.

[0021] The raw materials of the traditional Chinese medicine composition for treating neutral obesity further include, on the basis of the basic formula: rhubarb processed with vinegar, gynostemma pentaphyllum, magnolia officinalis, cassia seed, artemisia capillaris, motherwort, lycopus lucidus, plantago asiatica, astragalus membranaceus, atractylodes macrocephala, citrus reticulata peel, atractylodes lancea, prunella vulgaris, fritillaria thunbergii.

[0022] All of the above raw materials are traditional Chinese medicine raw materials that are both edible and medicinal.

[0023] The traditional Chinese medicine composition for treating hard abdominal obesity is composed of the following raw materials in parts by weight: 10 - 60 parts of corn silk, 10 - 60 parts of coix seed, 5 - 30 parts of radish seed, 10 - 60 parts of hawthorn, 10 - 50 parts of poria cocos, 10 - 60 parts of lotus leaf, 5 - 50 parts of alisma orientale, 10 - 60 parts of adzuki bean, 5 - 30 parts of rhubarb processed with vinegar, 10 - 30 parts of gynostemma pentaphyllum, 5 - 30 parts of magnolia officinalis, 5 - 30 parts of cassia seed, 5 - 30 parts of artemisia capillaris, 10 - 60 parts of motherwort, 5 - 50 parts of prunella vulgaris, 5 - 30 parts of fritillaria thunbergii.

[0024] The traditional Chinese medicine composition for treating soft abdominal obesity is composed of the following raw materials in parts by weight: 10 - 60 parts of corn silk, 10 - 60 parts of coix seed, 10 - 60 parts of adzuki bean, 5 - 30 parts of radish seed, 10 - 50 parts of poria cocos, 10 - 50 parts of lycopus lucidus, 5 - 50 parts of plantago asiatica, 10 - 50 parts of astragalus membranaceus, 5 - 30 parts of atractylodes macrocephala, 10 - 60 parts of hawthorn, 10 - 60 parts of lotus leaf, 5 - 50 parts of alisma orientale, 5 - 30 parts of citrus reticulata peel, 3 - 30 parts of atractylodes lancea.

[0025] The traditional Chinese medicine composition for treating neutral obesity is composed of the following raw materials in parts by weight: 10 - 60 parts of corn stigma, 10 - 60 parts of coix seed, 5 - 30 parts of radish seed, 10 - 60 parts of hawthorn, 10 - 60 parts of lotus leaf, 10 - 50 parts of poria cocos, 5 - 50 parts of alisma orientale, 10 - 60 parts of adzuki bean, 5 - 30 parts of rhubarb processed with vinegar, 10 - 30 parts of gynostemma pentaphyllum, 5 - 30 parts of magnolia officinalis, 5 - 30 parts of cassia seed, 5 - 30 parts of artemisia capillaris, 10 - 60 parts of motherwort, 10 - 50 parts of lycopus lucidus, 5 - 50 parts of plantain seed, 10 - 50 parts of astragalus membranaceus, 5 - 30 parts of atractylodes macrocephala, 5 - 30 parts of tangerine peel, 3 - 30 parts of atractylodes lancea, 5 - 50 parts of prunella vulgaris, 5 - 30 parts of fritillaria thunbergii.

[0026] The preparation method of the traditional Chinese medicine composition for treating abdominal obesity with medicine and food homology as raw materials includes the following steps:

[0027] (1) Weigh corn stigma, coix seed, radish seed, hawthorn, poria cocos, lotus leaf, alisma orientale, adzuki bean, rhubarb processed with vinegar, gynostemma pentaphyllum, magnolia officinalis, cassia seed, artemisia capillaris, motherwort, prunella vulgaris, fritillaria thunbergii according to the parts by weight. After drying the obtained raw materials, mix them evenly and grind them into powder. After grinding, pass through a 50 - 100 - mesh drug inspection sieve to make traditional Chinese medicine powder, and sterilize it under an ultraviolet germicidal lamp for 8 h to obtain intermediate I;

[0028] (2) Weigh corn stigma, coix seed, adzuki bean, radish seed, poria cocos, lycopus lucidus, plantain seed, astragalus membranaceus, atractylodes macrocephala, hawthorn, lotus leaf, alisma orientale, tangerine peel, atractylodes lancea according to the parts by weight. After drying the obtained raw materials, mix them evenly and grind them into powder. After grinding, pass through a 50 - 100 - mesh drug inspection sieve to make traditional Chinese medicine powder, and sterilize it under an ultraviolet germicidal lamp for 8 h to obtain intermediate II;

[0029] (3) Weigh corn stigma, coix seed, radish seed, hawthorn, lotus leaf, poria cocos, alisma orientale, adzuki bean, rhubarb processed with vinegar, gynostemma pentaphyllum, magnolia officinalis, cassia seed, artemisia capillaris, motherwort, lycopus lucidus, plantain seed, astragalus membranaceus, atractylodes macrocephala, tangerine peel, atractylodes lancea, prunella vulgaris, fritillaria thunbergii according to the parts by weight. After drying the obtained raw materials, mix them evenly and grind them into powder. After grinding, pass through a 50 - 100 - mesh drug inspection sieve to make traditional Chinese medicine powder, and sterilize it under an ultraviolet germicidal lamp for 8 h to obtain intermediate III.

[0030] (4) Make each of intermediate I, II, and III into oral preparations.

[0031] The oral preparations are tablets, dispersants, capsules, soft capsules, granules, pills, dripping pills, gels and liquid oral preparations.

[0032] The preparation process of the tablets in the oral preparation is as follows: Select each of Intermediate I, II, and III, add gypsum powder, common excipients and a binder, granulate, add a lubricant after drying, mix evenly, size the granules, and press tablets to obtain tablets; The common excipients are first a mixture of one or more of starch, powdered sugar, microcrystalline cellulose, inorganic salts, and mannitol; The binder is selected from one of distilled water or a 30% - 70% ethanol solution; The lubricant is selected from one of 0.1% - 1% magnesium stearate, 0.1% - 3% talc powder, or 0.1% - 0.3% colloidal silica.

[0033] The preparation process of the soft capsules in the oral preparation is as follows: Select each of Intermediate I, II, and III, add 1% - 15% polyethylene glycols, a plasticizer, a disintegrant, curcumin, iron oxide, a wetting agent, and a suspending agent, mix evenly, and fill into soft capsules; The plasticizer is selected from one of glycerol or polyhydric alcohols; The disintegrant is selected from one of dry starch or an effervescent disintegrant; The lubricant is selected from one of 30% - 70% ethanol or liquid paraffin; The suspending agent is selected from one of beeswax, aluminum monostearate, or ethyl cellulose.

[0034] (III) Beneficial effects

[0035] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0036] (1) The inventors have conducted a comprehensive study on the etiology and pathogenesis of obesity and the unique palpation diagnosis of the abdomen, and provided three related Chinese medicine compositions. Any disease can be classified into three types: cold, hot, or a mixture of cold and heat. The most common and obvious part of obesity is the abdomen of the human body, and the elasticity and hardness of the abdomen can reflect the nature of the disease. As we all know, thermal expansion and contraction is a basic physical phenomenon. For example, a hot balloon has stronger elasticity and hardness, while a cold balloon has less elasticity and hardness. The same is true for abdominal fat. From the perspective of traditional Chinese medicine, obesity is a disease of deficiency in the root and excess in the superficial. The deficiency in the root refers to spleen deficiency, and the excess in the superficial is phlegm, dampness, and stasis. Spleen deficiency leads to dysfunction of transportation and transformation, resulting in the accumulation of phlegm, dampness, and stasis, which stagnates the meridians. Phlegm, dampness, and stasis are converted into fat, resulting in local fat accumulation, which is common in the abdomen, buttocks, face, limbs, and other parts. Fat accumulated in the body and under the skin also has three changes: heat, cold, or a mixture of cold and heat. The heated fat shows strong elasticity (i.e. resistance) and feels hard, while the cold fat shows poor resistance and feels small hardness, while the cold-heat mixed fat shows elasticity (resistance) and hardness that is neither strong nor weak. After years of research, it is found that the fat of hard abdominal obesity is the heated type, the fat of soft abdominal obesity is the cold type, and the fat of neutral obesity is the cold-heat mixed type. The present invention organically combines the etiology and pathogenesis of obesity, spleen deficiency, phlegm, dampness, blood stasis and turbidity with abdominal palpation to prepare a special prescription for a specific disease, and all raw materials are of the same origin as medicine and food, without side effects, and has a good therapeutic effect on abdominal obesity, and the treatment is simple and practical, easy to promote and use, and does not require doctor's guidance.

[0037] (2) There is a common basic formula in all three groups of traditional Chinese medicine compositions, which is composed of the following raw materials: corn silk, coix seed, radish seed, hawthorn, lotus leaf, poria cocos, alisma orientale, and adzuki bean. In the basic formula, corn silk has the effect of promoting diuresis and removing dampness; coix seed has the effects of strengthening the spleen and promoting diuresis, dispelling obstruction and stopping diarrhea; radish seed has the effects of promoting digestion and relieving flatulence, descending qi and resolving phlegm; hawthorn has the effects of promoting digestion and strengthening the stomach, promoting qi circulation and removing stasis, reducing lipid and eliminating accumulation; lotus leaf has the effects of relieving summer heat and lifting yang, dispersing stasis and removing blood stasis; poria cocos has the effects of promoting diuresis and removing dampness, strengthening the spleen and calming the mind; alisma orientale has the effects of clearing away damp-heat, promoting urination, and promoting the movement of phlegm-fluid; adzuki bean has the effects of dispersing blood and promoting diuresis, detoxifying and expelling pus. The combination of these herbs has the effects of strengthening the spleen and promoting diuresis, promoting blood circulation and removing stasis, resolving phlegm and reducing lipid. If the basic formula is further combined with the remaining traditional Chinese medicine compositions for treating hard abdominal obesity: vinegar-processed rhubarb, gynostemma pentaphyllum, magnolia officinalis, cassia seed, artemisia capillaris, motherwort, prunella vulgaris, and fritillaria thunbergii, among which vinegar-processed rhubarb has the effects of clearing heat and eliminating accumulation, promoting blood circulation and removing stasis; gynostemma pentaphyllum has the effects of strengthening the spleen and resolving phlegm, clearing heat and detoxifying; magnolia officinalis has the effects of drying dampness and resolving phlegm, lowering qi and relieving fullness; cassia seed has the effects of clearing heat and improving eyesight, reducing lipid and promoting defecation; prunella vulgaris has the effects of clearing the liver and purging fire, dissipating binds and relieving swelling; fritillaria thunbergii has the effects of clearing heat and resolving phlegm, dissipating binds and detoxifying. Therefore, the traditional Chinese medicine composition for treating hard abdominal obesity has the effects of clearing heat and resolving dampness, promoting blood circulation and softening hardness, strengthening the spleen and eliminating turbidity, reducing lipid and losing weight. If the basic formula is further combined with the remaining traditional Chinese medicine compositions for treating soft abdominal obesity: lycopus lucidus, plantago asiatica, atractylodes macrocephala, citrus reticulata peel, atractylodes lancea, and astragalus membranaceus, among which lycopus lucidus has the effects of promoting blood circulation and removing stasis, promoting diuresis and reducing swelling; plantago asiatica has the effects of resolving phlegm and promoting urination, promoting diuresis and relieving diarrhea; atractylodes macrocephala has the effects of strengthening the spleen and replenishing qi, drying dampness and promoting diuresis; citrus reticulata peel has the effects of regulating qi and strengthening the spleen, drying dampness and resolving phlegm; atractylodes lancea has the effects of drying dampness and strengthening the spleen, expelling wind and dispelling cold; astragalus membranaceus has the effects of replenishing qi and consolidating the exterior, promoting granulation and inducing diuresis. Therefore, the traditional Chinese medicine composition for treating soft abdominal obesity has the effects of strengthening the spleen and removing dampness, promoting blood circulation and removing stasis, dispelling cold and eliminating turbidity, reducing lipid and losing weight. If the basic formula is further combined with the remaining traditional Chinese medicine compositions for treating neutral abdominal obesity: vinegar-processed rhubarb, gynostemma pentaphyllum, magnolia officinalis, cassia seed, artemisia capillaris, motherwort, lycopus lucidus, plantago asiatica, astragalus membranaceus, atractylodes macrocephala, citrus reticulata peel, atractylodes lancea, prunella vulgaris, and fritillaria thunbergii, which is actually the sum of the two groups of raw materials of the traditional Chinese medicine composition for treating hard abdominal obesity and the traditional Chinese medicine composition for treating soft abdominal obesity (where the weight ratio of the same drug only takes the maximum ratio of one of them), therefore, the traditional Chinese medicine composition for treating neutral abdominal obesity has the effects of strengthening the spleen and resolving dampness, promoting blood circulation and removing stasis, dispelling cold and clearing heat, resolving turbidity and eliminating phlegm, reducing lipid and losing weight.

[0038] (3) According to the different abdominal palpations, different compositions can be selected. According to the palpation requirements and judgment results of the inventor, it is very easy to determine whether the patient has hard abdominal obesity, soft abdominal obesity, or neutral abdominal obesity. If it is judged as hard abdominal obesity, the traditional Chinese medicine composition for treating hard abdominal obesity is selected; if it is judged as soft abdominal obesity, the traditional Chinese medicine composition for treating soft abdominal obesity is selected; if it is judged as neutral abdominal obesity, the traditional Chinese medicine composition for treating neutral abdominal obesity is selected.

[0039] (4) On the basis of ensuring the therapeutic effect of the original traditional Chinese medicine, for the convenience of patients' storage, carrying and taking, the present invention provides preparation methods for tablets and soft capsules, which can be directly taken with water, are safe and hygienic, convenient to carry and store, easy to produce and sell, and change the situation of "complicated administration methods of traditional Chinese medicine preparations". Detailed implementation manners

[0040] The following will combine the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without making creative efforts shall fall within the protection scope of the present invention.

[0041] The pharmacology of the traditional Chinese medicine in the traditional Chinese medicine composition of the present invention is as follows:

[0042] The pharmacology of the special traditional Chinese medicine in the basic formula for obesity in the present invention is as follows:

[0043] (1) Corn silk: sweet, neutral, promoting diuresis to alleviate edema, clearing dampness and promoting bile excretion.

[0044] (2) Coix seed: sweet, light, cool. Invigorating the spleen and promoting diuresis, expelling wind-dampness and stopping diarrhea, clearing heat and discharging pus. Taking it for a long time can make the body light and strengthen qi. Benefiting the intestines and stomach, eliminating edema, and promoting defecation and urination.

[0045] (3) Semen Raphani: pungent, sweet, neutral. Promoting digestion and relieving distension, descending qi and resolving phlegm.

[0046] (4) Hawthorn: sour, sweet, slightly warm. Promoting digestion and strengthening the stomach, promoting qi circulation and removing stasis. Digesting food, eliminating internal accumulation and mass. Treating spleen deficiency and damp-heat, digesting food and grinding accumulation, promoting urination and defecation. Modern pharmacological research shows that hawthorn has the effects of dilating blood vessels, reducing blood lipid, reducing blood pressure, strengthening the heart, contracting the uterus, antibacterial, sedative, etc. The fatty acids contained in hawthorn can promote fat digestion.

[0047] (5) Lotus leaf: bitter, neutral. Clearing heat and relieving summer heat, ascending the clear yang, cooling blood and stopping bleeding. Ascending yang qi, being able to disperse stasis and retain good blood. Modern pharmacology shows that lotus leaf has the effects of dilating blood vessels, spasmolysis, reducing blood pressure, reducing blood lipid, etc.

[0048] (6) Poria: sweet, light, neutral. Promoting diuresis and percolating dampness, strengthening the spleen and calming the mind. An important herb for promoting diuresis and removing dampness.

[0049] (7) Alisma orientale: sweet, cold. Functioning to promote urination, clearing damp-heat, and promoting the flow of phlegm. Modern pharmacological research shows that Alisma orientale has the effects of reducing blood lipid, anti-fatty liver, dilating coronary arteries, reducing blood sugar, etc.

[0050] (8) Adzuki bean: sweet, sour, neutral. Promoting diuresis to alleviate edema, detoxifying and discharging pus. Being able to descend and disperse blood and promote diuresis. Lower abdominal distension.

[0051] The special pharmacological effects of the traditional Chinese medicine composition for treating hard abdominal obesity in the present invention are as follows:

[0052] (1) Rhubarb processed with vinegar: Its purgative effect is slowed down, and it mainly functions to eliminate stagnation and promote blood circulation to remove stasis.

[0053] (2) Gynostemma pentaphyllum: Bitter, sweet, and cold in nature, it can replenish qi and strengthen the spleen, resolve phlegm and relieve cough, and clear heat and detoxify.

[0054] (3) Magnolia officinalis: Bitter, pungent, and warm in nature. It can dry dampness and resolve phlegm, lower qi and relieve fullness.

[0055] (4) Cassia seed: Sweet, bitter, salty, and slightly cold in nature. It can clear heat and improve eyesight, moisten the intestines and promote defecation. Modern pharmacological research shows that Cassia seed has the effects of lowering blood pressure, reducing serum cholesterol, inducing laxation, and antibacterial.

[0056] (5) Artemisia capillaris: Bitter, pungent, and slightly cold in nature. It can clear away damp-heat and relieve jaundice. Taking it for a long time can make the body light and improve endurance. It has a light taste and promotes diuresis, and is a specific medicine for treating damp-heat in the spleen and stomach. It is also an important medicine for removing dampness and dissipating nodules. Modern pharmacological research shows that Artemisia capillaris has the effects of promoting bile secretion, protecting the liver, reducing blood lipid, dilating coronary arteries, lowering blood pressure, relieving fever, killing roundworms, and resisting dermatophytes.

[0057] (6) Leonurus japonicus: Bitter, pungent, and slightly cold in nature. It can promote blood circulation to regulate menstruation and induce diuresis to reduce swelling. It promotes blood circulation without damaging new blood, and nourishes blood without stagnating stasis, and is truly a holy medicine for the blood system.

[0058] (7) Prunella vulgaris: Pungent, bitter, and slightly cold in nature. It can soothe the liver fire, relieve internal heat, and disperse stagnant qi. It can break hard masses, fistulas, and nodular qi, and disperse scrofula, cervical lymph node tuberculosis, and head sores. It can expel cold and heat, and also relieve damp arthralgia.

[0059] (8) Fritillaria thunbergii: Bitter, cold, and slightly pungent in nature. It can clear heat and resolve phlegm, disperse nodules and dissipate abscesses. It can relieve depression and disperse nodules, and promote blood circulation.

[0060] The special pharmacological effects of the traditional Chinese medicine composition for treating soft abdominal obesity in the present invention are as follows:

[0061] (1) Lycopus lucidus: Bitter, pungent, and slightly warm in nature. It can promote blood circulation to remove stasis and induce diuresis to reduce swelling. Lycopus lucidus acts on the blood aspect and reduces edema, and is a specific medicine for treating blood transformed into water.

[0062] (2) Plantago asiatica: Sweet and slightly cold in nature. It can promote diuresis and relieve stranguria, percolate dampness and stop diarrhea, clear the liver and improve eyesight, and clear the lung and resolve phlegm. Taking it for a long time can make the body light and improve endurance.

[0063] (3) Atractylodes macrocephala: Pungent, bitter, sweet, and warm in nature. It can strengthen the spleen and replenish qi, dry dampness and promote diuresis, stop sweating, and prevent miscarriage. Taking it for a long time can make the body light and prolong life without hunger. It can strengthen the spleen and stomach, mainly treat muscle heat, limb fatigue, listlessness, drowsiness, and loss of appetite.

[0064] (4) Pericarpium Citri Reticulatae: Bitter, pungent, and warm in nature. It can regulate qi and strengthen the spleen, dry dampness and resolve phlegm. It can treat indigestion and resolve phlegm, and relieve heat in the chest.

[0065] Atractylodes lancea: pungent, bitter, warm. Dry dampness and strengthen the spleen, dispel wind and cold, improve eyesight. It can promote the rising of yang qi in the spleen, disperse stagnation, induce sweating and remove dampness. It is suitable for those with a plump body and excessive dampness, and those with a thin body and excessive internal heat should avoid it.

[0066] (6) Astragalus membranaceus: sweet, warm. Tonify qi and consolidate the exterior, promote diuresis and expel toxins, discharge pus, astringe sores and promote granulation. It is good at treating weakness of the spleen and stomach.

[0067] In the present invention, the traditional Chinese medicine composition for treating neutral obesity is composed of the addition of the traditional Chinese medicine composition for treating hard abdominal obesity and the traditional Chinese medicine composition for treating soft abdominal obesity. Therefore, its special traditional Chinese medicine pharmacology has been described above and will not be repeated.

[0068] Example 1:

[0069] A traditional Chinese medicine composition for treating abdominal obesity with medicine and food homology as raw materials, comprising the following raw materials: corn stigma, coix seed, radish seed, hawthorn, lotus leaf, poria cocos, alisma orientale, adzuki bean, as the basic formula. This basic formula is the common part of the traditional Chinese medicine composition for treating hard abdominal obesity, the traditional Chinese medicine composition for treating soft abdominal obesity and the traditional Chinese medicine composition for treating neutral obesity. The traditional Chinese medicine composition for treating hard abdominal obesity further comprises rhubarb processed with vinegar, gynostemma pentaphyllum, magnolia officinalis, cassia seed, capillaris, motherwort, prunella vulgaris, fritillaria thunbergii; the traditional Chinese medicine composition for treating soft abdominal obesity further comprises eupatorium japonicum, plantain seed, atractylodes macrocephala, citrus reticulata, atractylodes lancea, astragalus membranaceus; the traditional Chinese medicine composition for treating neutral obesity further comprises rhubarb processed with vinegar, gynostemma pentaphyllum, magnolia officinalis, cassia seed, capillaris, motherwort, prunella vulgaris, fritillaria thunbergii, eupatorium japonicum, plantain seed, atractylodes macrocephala, citrus reticulata, atractylodes lancea, astragalus membranaceus. The traditional Chinese medicine composition for treating hard abdominal obesity has the effects of clearing heat and promoting dampness, activating blood circulation and softening hardness, strengthening the spleen and removing turbidity, reducing lipid and losing weight; the traditional Chinese medicine composition for treating soft abdominal obesity has the effects of strengthening the spleen and removing dampness, promoting blood circulation and removing stasis, dispelling cold and removing turbidity, reducing lipid and losing weight; the traditional Chinese medicine composition for treating neutral obesity has the effects of strengthening the spleen and resolving dampness, promoting blood circulation and removing stasis, dispelling cold and clearing heat, removing turbidity and dispelling stasis, reducing lipid and losing weight.

[0070] The traditional Chinese medicine composition for treating hard abdominal obesity is composed of the following raw materials in parts by weight: 10 - 60 parts of corn stigma, 10 - 60 parts of coix seed, 5 - 30 parts of radish seed, 10 - 60 parts of hawthorn, 10 - 50 parts of poria cocos, 10 - 60 parts of lotus leaf, 5 - 50 parts of alisma orientale, 10 - 60 parts of adzuki bean, 5 - 30 parts of rhubarb processed with vinegar, 10 - 30 parts of gynostemma pentaphyllum, 5 - 30 parts of magnolia officinalis, 5 - 30 parts of cassia seed, 5 - 30 parts of capillaris, 10 - 60 parts of motherwort, 5 - 50 parts of prunella vulgaris, 5 - 30 parts of fritillaria thunbergii.

[0071] The traditional Chinese medicine composition for treating soft abdominal obesity is composed of the following raw materials in parts by weight: 10-60 parts of corn stigma, 10-60 parts of coix seed, 10-60 parts of adzuki bean, 5-30 parts of radish seed, 10-50 parts of poria cocos, 10-50 parts of eupatorium japonicum, 5-50 parts of plantain seed, 10-50 parts of astragalus membranaceus, 5-30 parts of atractylodes macrocephala, 10-60 parts of hawthorn, 10-60 parts of lotus leaf, 5-50 parts of alisma orientale, 5-30 parts of tangerine peel, 3-30 parts of atractylodes lancea.

[0072] The traditional Chinese medicine composition for treating neutral obesity is composed of the following raw materials in parts by weight: 10-60 parts of corn stigma, 10-60 parts of coix seed, 5-30 parts of radish seed, 10-60 parts of hawthorn, 10-60 parts of lotus leaf, 10-50 parts of poria cocos, 5-50 parts of alisma orientale, 10-60 parts of adzuki bean, 5-30 parts of vinegar-processed rheum officinale, 10-30 parts of gynostemma pentaphyllum, 5-30 parts of magnolia officinalis, 5-30 parts of cassia obtusifolia, 5-30 parts of artemisia capillaris, 10-60 parts of gynostemma pentaphyllum, 10-50 parts of eupatorium japonicum, 5-50 parts of plantain seed, 10-50 parts of astragalus membranaceus, 5-30 parts of atractylodes macrocephala, 5-30 parts of tangerine peel, 3-30 parts of atractylodes lancea, 5-50 parts of prunella vulgaris, 5-30 parts of fritillaria thunbergii.

[0073] The operation steps of the preparation method of the traditional Chinese medicine composition for treating abdominal obesity are as follows:

[0074] (1) Weigh corn stigma, coix seed, radish seed, hawthorn, poria cocos, lotus leaf, alisma orientale, adzuki bean, vinegar-processed rheum officinale, gynostemma pentaphyllum, magnolia officinalis, cassia obtusifolia, artemisia capillaris, leonurus japonicus, prunella vulgaris, fritillaria thunbergii according to the parts by weight. After drying the obtained raw materials, mix them evenly and grind them into powder. After grinding, pass through a 50-100 mesh drug inspection sieve to make traditional Chinese medicine powder, and sterilize it under an ultraviolet germicidal lamp for 8 hours to obtain intermediate I;

[0075] (2) Weigh corn stigma, coix seed, adzuki bean, radish seed, poria cocos, eupatorium japonicum, plantain seed, astragalus membranaceus, atractylodes macrocephala, hawthorn, lotus leaf, alisma orientale, tangerine peel, atractylodes lancea according to the parts by weight. After drying the obtained raw materials, mix them evenly and grind them into powder. After grinding, pass through a 50-100 mesh drug inspection sieve to make traditional Chinese medicine powder, and sterilize it under an ultraviolet germicidal lamp for 8 hours to obtain intermediate II;

[0076] (3) Weigh corn stigma, coix seed, radish seed, hawthorn, lotus leaf, poria cocos, alisma orientale, adzuki bean, vinegar-processed rheum officinale, gynostemma pentaphyllum, magnolia officinalis, cassia obtusifolia, artemisia capillaris, leonurus japonicus, eupatorium japonicum, plantain seed, astragalus membranaceus, atractylodes macrocephala, tangerine peel, atractylodes lancea, prunella vulgaris, fritillaria thunbergii according to the parts by weight. After drying the obtained raw materials, mix them evenly and grind them into powder. After grinding, pass through a 50-100 mesh drug inspection sieve to make traditional Chinese medicine powder, and sterilize it under an ultraviolet germicidal lamp for 8 hours to obtain intermediate III.

[0077] (4) Make each of intermediate I, II, and III into oral preparations.

[0078] The oral preparations are tablets, dispersible tablets, capsules, soft capsules, granules, pills, dripping pills, gels and oral liquid preparations.

[0079] The preparation process of the tablets in the oral preparations is as follows: Select each of Intermediate I, II, and III, add gypsum powder, common excipients and adhesives, mix them, granulate, add lubricants after drying, mix evenly, size the granules, and press tablets to obtain tablets; The common excipients are first a mixture of one or more of starch, powdered sugar, microcrystalline cellulose, inorganic salts and mannitol; The adhesive is selected from one of distilled water or a 30% - 70% ethanol solution; The lubricant is selected from one of 0.1% - 1% magnesium stearate, 0.1% - 3% talc powder or 0.1% - 0.3% colloidal silica.

[0080] The preparation process of the soft capsules in the oral preparations is as follows: Select each of Intermediate I, II, and III, add 1% - 15% polyethylene glycols, plasticizers, disintegrants, curcumin, iron oxide, wetting agents and suspending agents, mix evenly, and fill into soft capsules; The plasticizer is selected from one of glycerol or polyhydric alcohols; The disintegrant is selected from one of dry starch or effervescent disintegrants; The lubricant is selected from one of 30% - 70% ethanol or liquid paraffin; The suspending agent is selected from one of beeswax, aluminum monostearate or ethyl cellulose.

[0081] On the basis of ensuring the therapeutic effect of the original traditional Chinese medicine, in order to facilitate storage, carrying and taking for patients, methods for preparing tablets and soft capsules are provided. They can be taken directly with water, are safe and hygienic, convenient for carrying and storing, easy to produce and sell, and change the situation of "complicated taking methods of traditional Chinese medicine preparations". Moreover, the compatibility of the traditional Chinese medicine composition provided by the present invention is reasonable. It combines the pathogenesis of obesity, spleen deficiency, phlegm-dampness and stasis turbidity with abdominal palpation to prepare a unique special prescription for a specific disease, and all use raw materials of both medicine and food, without side effects. It has a very good therapeutic effect on abdominal obesity, and does not rebound. It has the characteristics of being simple and practical, easy to promote and apply, and does not require doctor's guidance.

[0082] Clinical efficacy tracking was carried out on the traditional Chinese medicine composition disclosed by the present invention, and the treatment results are as follows:

[0083] 1. Selection of patients:

[0084] 900 patients with abdominal obesity were selected. According to the clinical manifestations and abdominal palpation results, the patients were randomly selected into the treatment group and the control group. Among them, there were 150 cases of hard abdominal obesity, 150 cases of soft abdominal obesity, and 150 cases of neutral abdominal obesity. These three types were treated with the corresponding traditional Chinese medicine compositions; Control group: The remaining 450 cases were divided into equal numbers according to different groups and were all treated with lipid-lowering and weight-reducing tablets as a control.

[0085] 2. Efficacy criteria: According to the efficacy judgment criteria for the treatment of obesity in the "Guiding Principles for Clinical Research of New Traditional Chinese Medicines for the Treatment of Obesity", the efficacy criteria are as follows:

[0086] (1) Recent recovery: The weight loss has reached the standard weight or is within the overweight range, and the related symptoms have disappeared for more than 3 months.

[0087] (2) Marked effect: The weight loss is more than 5 Kg or the percentage of body fat decreases by more than 5%, and the related symptoms basically disappear.

[0088] (3) Effective: The weight loss is more than 3 kg or the percentage of body fat decreases by more than 1%, and the related symptoms are alleviated.

[0089] (4) Ineffective: The weight loss is less than 3 kg and the percentage of body fat decreases by less than 1%, and the related symptoms are not alleviated.

[0090] Note: Body weight: That is, the weight of the human body, usually measured in kilograms (kg). It is an important indicator reflecting the health status and nutritional status of the human body. Percentage of body fat: It refers to the percentage of the weight of human body fat in the total body weight of the human body, also known as the body fat rate. It is a key indicator for measuring the body fat content of the human body and can more accurately reflect the degree of obesity and health status of the body.

[0091] 3. Treatment course: Three months is one treatment course.

[0092] 4. Treatment effect: Observe the results after one treatment course, and the total effective rate is unified according to the effective and above results.

[0093] 5. Comparison of the curative effects between the treatment group and the control group:

[0094] (1) Comparison of the curative effect between the hard abdominal obesity group and the control group:

[0095]

[0096]

[0097] (2) Comparison of the curative effect between the soft abdominal obesity group and the control group:

[0098] Comparison group Recently cured Markedly effective Effective Ineffective Total effective rate Treatment group 120 21 9 0 100％ Control group 5 13 43 89 40.67％

[0099] (3) Comparison of the curative effect between the neutral obesity group and the control group:

[0100] Comparison group Recently cured Markedly effective Effective Ineffective Total effective rate Treatment group 115 24 11 0 100％ Control group 7 39 42 62 58.67％

[0101] 6. Results of the continuous treatment after one treatment course of the control group is ineffective:

[0102] After one course of treatment in the control group, 202 patients showed no effect, and subsequently all switched to the treatment plan of the treatment group. After another course of treatment (3 months), the results were as follows: 141 cases were cured recently (accounting for 69.8%), 48 cases showed marked effect (accounting for 23.76%), 13 cases were effective (accounting for 6.44%), and 0 cases showed no effect. The total effective rate was 100%.

[0103] Application Example 1

[0104] Wei XX, male, 35 years old, an employee. The patient has had a history of obesity for 5 years. Usually, he smokes and drinks alcohol and eats supper almost every day. In the past two months, he has felt abdominal distension and discomfort, dry mouth and bitter taste, and sticky and stinky stools. He came to our station for treatment. His height is 172 cm and his weight is 82 kg. His tongue is light red and his tongue coating is yellow and greasy. His abdomen is distended. On abdominal palpation, there is a strong sense of resistance and the abdomen is relatively hard. It belongs to the hard-abdomen type of obesity, and the traditional Chinese medicine composition for treating hard-abdomen type obesity is given. After a 2-week follow-up visit, the abdominal distension improved significantly, the dry mouth and bitter taste also improved, the stools returned to normal, the sense of resistance on abdominal palpation decreased, and the hardness also decreased compared with before. Two months later, the weight decreased to 67 kg, all symptoms disappeared, and the sense of resistance and hardness on abdominal palpation had eased and become moderate.

[0105] Application Example 2

[0106] Zhu XX, female, 25 years old, unemployed after graduating from university. Two years ago, after taking western medicine for anxiety disorder (the specific medicine is unknown), she began to gain weight. After stopping taking western medicine, her weight continued to increase, so she came to our station for treatment. Her height is 162 cm and her weight is 70 kg. Her tongue is light red, her tongue coating is light yellow and greasy, and her pulse is slippery. On abdominal palpation, the sense of resistance is moderate, neither strong nor weak, and the abdomen feels neither hard nor soft. It belongs to the neutral type of obesity, and the traditional Chinese medicine composition for treating neutral type obesity is given. Two and a half months later, the weight dropped to 56 kg and the abdominal palpation was moderate.

[0107] Application Example 3

[0108] Ma XX, male, 38 years old, an employee. The patient has been obese for three years, with a large abdomen and a large face, fatigue, and loose stools, two to three times a day. His height is 171 cm and his weight is 73 kg. His abdomen is flabby. On abdominal palpation, the sense of resistance is weak and the hardness is soft, with a soft feeling. His tongue is light red, his tongue coating is white, slippery and greasy, and his pulse is weak. It belongs to the soft-abdomen type of obesity. The traditional Chinese medicine complex for treating soft-abdomen type obesity is given. After a 2-week follow-up visit, the fatigue disappeared, the stools formed, once a day. The large abdomen and large face improved significantly. The weight dropped to 65 kg. The abdomen was no longer flabby, the elasticity on palpation increased, and the hardness was stronger than before.

[0109] Although the embodiments of the present invention have been shown and described, it cannot be determined that the specific implementation of the present invention is only limited to these descriptions. For those of ordinary skill in the art, it can be understood that various changes, modifications, substitutions, and variations can be made to these embodiments without departing from the principles and spirit of the present invention. The scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A Chinese medicine composition for treating abdominal obesity, which is made of edible and medicinal ingredients, comprising the following ingredients: corn silk, coix seeds, radish seeds, hawthorn, lotus leaves, Poria cocos, oriental water chestnuts, and red beans. The composition is characterized by: The Chinese medicine composition for treating hard abdominal obesity, the Chinese medicine composition for treating soft abdominal obesity and the Chinese medicine composition for treating neutral obesity all have the raw materials of the Chinese medicine composition. At the same time, the raw materials of the Chinese medicine composition for treating hard abdominal obesity also include vinegar-processed rhubarb, gynostemma pentaphyllum, magnolia bark, cassia seed, wormwood, motherwort, selfheal and thunbergii; the raw materials of the Chinese medicine composition for treating soft abdominal obesity also include zedoaria, plantago, astragalus, atractylodes, tangerine peel and atractylodes; the raw materials of the Chinese medicine composition for treating neutral obesity also include vinegar-processed rhubarb, gynostemma pentaphyllum, magnolia bark, cassia seed, wormwood, motherwort, zedoaria, plantago, astragalus, atractylodes, tangerine peel, atractylodes, selfheal and thunbergii.

2. A Chinese medicine composition for treating abdominal obesity with medicinal and edible ingredients as raw materials according to claim 1, wherein the Chinese medicine composition for treating hard abdominal obesity is composed of the following raw materials in parts by weight: 10-60 parts of corn silk, 10-60 parts of coix seed, 5-30 parts of radish seed, 10-60 parts of hawthorn, 10-50 parts of Poria, 10-60 parts of lotus leaf, 5-50 parts of Alisma, 10-60 parts of adzuki bean, 5-30 parts of vinegar-processed rhubarb, 10-30 parts of Gynostemma pentaphyllum, 5-30 parts of Magnolia officinalis, 5-30 parts of Cassia seed, 5-30 parts of Artemisia capillaris, 10-60 parts of Leonurus japonicus, 5-50 parts of Prunella vulgaris, and 5-30 parts of Fritillaria thunbergii.

3. A Chinese medicine composition for treating abdominal obesity with medicinal and edible ingredients as raw materials according to claim 1, wherein the Chinese medicine composition for treating soft abdominal obesity is composed of the following raw materials in parts by weight: 10-60 parts of corn silk, 10-60 parts of coix seed, 10-60 parts of red bean, 5-30 parts of radish seed, 10-50 parts of Poria, 10-50 parts of Zedoaria, 5-50 parts of Plantago, 10-50 parts of Astragalus, 5-30 parts of Atractylodes, 10-60 parts of Hawthorn, 10-60 parts of lotus leaf, 5-50 parts of Alisma, 5-30 parts of tangerine peel, and 3-30 parts of Atractylodes.

4. A Chinese medicine composition for treating abdominal obesity with both medicinal and edible ingredients as raw materials as claimed in claim 1, wherein the Chinese medicine composition for treating neutral obesity is composed of the following raw materials in parts by weight: 10-60 parts of corn silk, 10-60 parts of coix seed, 5-30 parts of radish seed, 10-60 parts of hawthorn, 10-60 parts of lotus leaf, 10-50 parts of Poria, 5-50 parts of Alisma, 10-60 parts of adzuki bean, 5-30 parts of vinegar-processed rhubarb, 10-30 parts of Gynostemma pentaphyllum, 5-30 parts of Magnolia officinalis, 5-30 parts of Cassia seed, 5-30 parts of Artemisia capillaris, 10-60 parts of Motherwort, 10-50 parts of Zedoaria, 5-30 parts of Plantago seed, 10-50 parts of Astragalus, 5-30 parts of Atractylodes, 5-30 parts of Tangerine peel, 3-30 parts of Atractylodes, 5-50 parts of Prunella Vinegar, and 5-30 parts of Fritillaria thunbergii.

5. A method for preparing a Chinese medicine composition for treating abdominal obesity as claimed in claim 1, characterized in that: The steps include: Weigh corn silk, coix seed, radish seed, hawthorn, Poria, lotus leaf, oriental rhizome, red bean, vinegar-processed rhubarb, gynostemma pentaphyllum, Magnolia officinalis, cassia seed, wormwood, motherwort, selfheal, and thunbergia thunbergii by weight, dry the obtained raw materials, mix them evenly, grind them into powder, pass through a 50-100 mesh drug inspection sieve to prepare Chinese medicine powder, and sterilize them under an ultraviolet germicidal lamp for 8 hours to obtain intermediate I; Weigh corn silk, coix seed, adzuki bean, radish seed, poria, zedoaria, plantain seed, astragalus, atractylodes, hawthorn, lotus leaf, oriental rhizome, tangerine peel and atractylodes lancea according to weight, dry the obtained raw materials, mix them evenly and grind them into powder, pass through a 50-100 mesh drug inspection sieve to make Chinese medicine powder, and sterilize them under an ultraviolet germicidal lamp for 8 hours to obtain intermediate II; Weigh corn silk, coix seed, radish seed, hawthorn, lotus leaf, Poria, oriental rhubarb, red bean, vinegar-processed rhubarb, Gynostemma pentaphyllum, Magnolia officinalis, Cassia seed, Artemisia capillaris, Leonurus japonicus, Zedoariae rhizome, Plantago seed, Astragalus, Atractylodes macrocephala, tangerine peel, Atractylodes lancea, Prunella vulgaris and Fritillaria thunbergii by weight, dry the obtained raw materials, mix them evenly and grind them into powder, pass through a 50-100 mesh drug inspection sieve to prepare Chinese medicine powder after grinding, and sterilize under an ultraviolet germicidal lamp for 8 hours to obtain intermediate III; prepare oral preparations from one, two or three of intermediates I, II and III.

6. A method for preparing a Chinese medicine composition for treating abdominal obesity as claimed in claim 5, characterized in that: The oral preparations are tablets, dispersants, soft capsules, granules, pills, drop pills, gels and oral liquid preparations.

7. A method for preparing a Chinese medicine composition for treating abdominal obesity as claimed in claim 6, characterized in that: The preparation process of the tablets in the oral preparation is as follows: one or two or three of the intermediates I, II, and III are added with gypsum powder, common auxiliary materials and adhesives, mixed, granulated, dried, added with lubricants, mixed, granulated, and tableted to obtain tablets; the common auxiliary materials are selected from one or a mixture of two or more of starch, powdered sugar, microcrystalline cellulose, inorganic salts and mannitol; the adhesive is selected from one of distilled water or 30% to 70% ethanol solution; the lubricant is selected from one of 0.1% to 1% magnesium stearate, 0.1% to 3% talc or 0.1% to 0.3% micro powder silica gel.

8. A method for preparing a Chinese medicine composition for treating abdominal obesity as claimed in claim 6, characterized in that: The preparation process of the soft capsule in the oral preparation is as follows: select one, two or three of the intermediates I, II and III, add 1% to 15% of polyethylene glycol, plasticizer, disintegrant, curcumin, iron oxide, wetting agent and suspending agent, mix well, and fill the soft capsule; the plasticizer is selected from glycerol or one of polyols; the disintegrant is selected from dry starch or one of effervescent disintegrants; The wetting agent is selected from one of 30% to 70% ethanol or liquid paraffin; the suspending agent is suitable for one of beeswax, aluminum monostearate or ethyl cellulose.

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