Ambroxol hydrochloride oral solution and preparation method thereof

Abstract

The invention discloses an ambroxol hydrochloride oral solution and a preparation method thereof, and relates to a preparation method of western medicine, in particular to a medical production formula used for curing bronchitis and a preparation method thereof; the preparation method comprises the following steps: sucrose, preservatives and purified water are dissolved in a mixing mode so as to prepare simple syrup; the ambroxol hydrochloride, corrigents and preservatives are dissolved by the purified water so as to prepare ambroxol hydrochloride solution; the ambroxol hydrochloride solution and the simple syrup are stirred and mixed evenly, the corrigents and the preservatives are added successively and discontinuously and then the purified water is added to adjust the concentration. The invention has simple and reasonable process, and is easy to operate practically and the produced products have good stability; the products can used as common phlegm-eliminating drugs, has functions of increasing the liquid level of the respiratory tract, reducing mucus secretion, enhancing the secretion of pulmonary surfactant and the movement of cilium and preventing cough to a certain extent, and is applicable to acute respiratory disease and chronic respiratory disease, such as ropy sputum and difficult cough caused by acute bronchitis and chronic bronchitis, bronchial asthma and pulmonary tuberculosis, etc.

Description

Technical field [0001] The present invention relates to a preparation method of medicine, in particular to a production formula and preparation method of medicine for treating bronchitis. Background technique [0002] As we all know, ambroxol hydrochloride has the functions of relieving asthma and cough, and is used as an active ingredient in the current medical community. Currently, most of the drugs on the market with ambroxol hydrochloride as the active ingredient are solid preparations, injections or compound preparations, which are taken by children. , one tablet or pill needs to be divided into several portions, and the dosage is difficult to control accurately. Secondly, it has a spicy taste, and children are reluctant to take it actively, which greatly affects the treatment effect. In addition, fixed preparations need to be disintegrated first and then dissolved before the human body can absorb them, and the absorption speed and onset of effect are slow. Contents o...

AI Technical Summary

Problems solved by technology

[0002] As we all know, ambroxol hydrochloride has the functions of relieving asthma and antitussive, and the existing medical field uses it as an active ingredient. At present, most of the medicines with ambroxol hydrochloride as the active ingredient in the market are solid preparations, injections or compound preparations. Children take it , it is necessary to divide a tablet or a pill into several doses, and the dose is difficult to control accurately. Secondly, it has a spicy taste of the drug, and children are reluctant to take it actively, which greatly affects the therapeutic effect

In addition, the fixed preparation needs to be disintegrated first, and then dissolved, so that the human body can absorb it, and the absorption speed and onset of effect are slow