Ambroxol hydrochloride granule

A technology of ambroxol hydrochloride and granules, which is applied in the field of ambroxol hydrochloride granules, can solve the problems of not being able to be made satisfactorily, taking and being convenient to carry, losing practical application value, and being inconvenient for children to take. Caking, long retention period, and stable drug effect

Inactive Publication Date: 2005-06-22
北京金康驰医药投资有限公司
View PDF0 Cites 15 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Because ambroxol hydrochloride has extremely strong bitter taste, so present ambroxol hydrochloride preparation dosage form is based on capsule, tablet and oral liquid, and these dosage forms are inconvenient for children to take, but can't be made into another person's satisfaction at present, Granules that meet drug standards and are easy to take and carry, easy to absorb, and suitable for children
The major difficulty in preparing granules with ambroxol hydrochlor

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] 10 g of ambroxol hydrochloride, 200 g of lactose, 650 g of sucrose, 3 g of stevioside, 15 g of firmenich and orange essence, and an appropriate amount of 1% povidone PVP solution are prepared into granules.

Embodiment 2

[0035] 17g of ambroxol hydrochloride, 600g of lactose, 500g of sucrose, 27g of stevioside, 130g of Firmenich and orange essence, and an appropriate amount of copovidone S-630 were prepared into granules.

Embodiment 3

[0037] 15g of ambroxol hydrochloride, 515g of lactose, 500g of sucrose, 10g of stevioside, 60g of firmenich, 40g of orange essence and an appropriate amount of 1% povidone PVP solution are prepared into granules.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses an ambroxol hydrochloride granule, whose ingredients (by weight ratio) include ambroxol hydrochloride 10-17 parts, lactose 170-670 parts, sucrose 170-670 parts, stevioside 3-27 parts, Firmenich and fragrant citrus essence 3-138 parts, and right amount of binding agent. The invention relates to an ambroxol hydrochloride pelletized granule has the advantages of convenience in carrying, accurate quantitative determination, good taste, high biological availability, thus is especially suitable for children.

Description

technical field [0001] The invention relates to a medicine for treating acute and chronic respiratory diseases, in particular to ambroxol hydrochloride granules. Background technique [0002] Ambroxol hydrochloride is mainly used for thick sputum and difficulty in coughing up sputum caused by acute and chronic respiratory diseases. , and increase the concentration of antibiotics in bronchial secretions, which have antioxidant and anti-inflammatory effects. Ambroxol hydrochloride is widely used clinically for the treatment of respiratory diseases, the treatment of children's respiratory tract infection, the treatment of neonatal respiratory tract infection and the combined use of hormones to prevent neonatal hyaline membrane disease, the treatment of children's asthma, otitis media with otitis media, etc. Treatment and postoperative lung function of elderly patients with breast cancer has a certain protective effect. It is a kind of drug with little toxicity, safe and effect...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K9/16A61K31/137A61P11/00
Inventor 赵敬民赵良彬
Owner 北京金康驰医药投资有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap