3 results about "Bronchitic asthma" patented technology

FIELD: pediatrics and pulmonology.SUBSTANCE: used to predict the risk of severe bronchial asthma in children. Anamnesis is collected, blood is taken, and the child's blood is tested in a laboratory. From the anamnesis, the duration of the disease in years and the number of exacerbations over the current 12 months in points are specified. The peak expiratory flow rate is measured using a peak flow meter, %. The concentration of connexin 43 (CX43), ng / ml, is determined in the child’s blood serum at the time of inclusion in the study. The prognosis for the risk of severe bronchial asthma in children P is calculated using the stated formula. If the P value is 0.52 or higher, a high risk of severe bronchial asthma is predicted.EFFECT: method provides the possibility of increasing the accuracy and reliability of the prognosis of the severity of bronchial asthma in children by taking into account the declared clinical symptoms and risk factors for bronchial asthma in children and adolescents of both sexes who do not have signs of a severe course of the disease at the time of examination.1 cl, 4 ex

This invention belongs to the field of traditional Chinese medicine composition technology, specifically relating to a traditional Chinese medicine composition and preparation for treating bronchial asthma. The traditional Chinese medicine composition consists of the following raw materials in parts by weight: 9-11 parts Perilla seed, 6-8 parts White mustard seed, 6-8 parts Lepidium seed, 6-8 parts Radish seed, 4-6 parts Scutellaria baicalensis, 9-11 parts Houttuynia cordata, 3-5 parts Prepared Ephedra, 4-6 parts Fresh Fritillaria cirrhosa, 5-7 parts Magnolia officinalis, and 3-5 parts Schisandra chinensis. This invention not only benefits lung qi and promotes proper lung function, but also addresses the issue that impaired lung function can lead to stagnant heat and dampness. Therefore, Scutellaria baicalensis and Houttuynia cordata are used to clear heat, purge fire, and dry dampness. Persistent wheezing inevitably depletes lung qi, damages lung fluids, and harms kidney essence. Therefore, Schisandra chinensis is used to astringe the lungs, nourish the kidneys, generate fluids, and consolidate essence, restoring normal lung function and benefiting both the lungs and kidneys, thus relieving wheezing.

Disclosed herein are compounds useful for the inhibition of STAT6. The compounds have a general Formula (I) or (II) or pharmaceutically acceptable salts thereof, wherein the variables of Formula (I) and (II) are as defined herein. Also provided herein are pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, diseases / disorders related to the activity of STAT6, such as an allergic disease or an inflammatory disease, including but not limited to atopic dermatitis or bronchial asthma. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula (I) and (II).