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Composition for treating asthmatic bronchitis and bronchial asthma and preparation thereof

A bronchial asthma and bronchitis technology, applied in the field of medicine, can solve the problems of high incidence of bronchial asthma, difficulty in obtaining effective treatment of traditional Chinese medicine, difficulty in accepting traditional Chinese medicine decoction, etc., to achieve prolonged medication time, easy to carry and use, and definite curative effect Effect

Active Publication Date: 2010-12-29
HANGZHOU ZHONGMEI HUADONG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, clinical decoctions are mostly used, and there are few patented medicines. When prescribing decoctions, each patient must be dialectical. Therefore, it is difficult for patients in areas with underdeveloped medical resources to receive effective treatment from traditional Chinese medicine.
And children's asthmatic bronchitis and bronchial asthma sickness rate are high again, are difficult to accept to Chinese medicine decoction, so need badly a kind of preparation that can facilitate children's medication

Method used

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  • Composition for treating asthmatic bronchitis and bronchial asthma and preparation thereof
  • Composition for treating asthmatic bronchitis and bronchial asthma and preparation thereof
  • Composition for treating asthmatic bronchitis and bronchial asthma and preparation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Weigh 1500g of ephedra, 2500g of honeysuckle, 1500g of peucedanum, 3500g of Daqingye, 3500g of dandelion, 2500g of pinellia chinensis, 2000g of inula inula, 2500g of chuanxiong, add 8 times the amount of water, soak at 80°C for 50 minutes, and filter; Add 6 times the amount of water, and soak at 80°C for 40 minutes; combine the second soaking solutions and concentrate to 1:2 (crude drug: medicinal solution) to obtain a warm soaking concentrate. Dissolve chitosan with 1% acetic acid solution to prepare 1% chitosan solution, take 10% chitosan solution of warm soaking concentrated solution, add warm soaking concentrated solution. Leave it overnight, filter by centrifugation, and concentrate under reduced pressure to a relative density of 1.34 to obtain 4400 g of the filtered concentrate. Add 264g (filter concentrate 6%) acrylic resin No. II, add 12% NaOH solution under stirring, adjust to pH 7.2, leave to gel, and pack in plastic tubes, each 6 grams.

Embodiment 2

[0034] Weigh 1000g of ephedra, 2000g of honeysuckle, 1000g of peucedanum, 3000g of Daqingye, 3000g of dandelion, 2000g of pinellia chinensis, 1500g of inula inula, 2000g of chuanxiong, add 8 times the amount of water, soak at 80°C for 50 minutes, and filter; Add 6 times the amount of water, and soak at 80°C for 40 minutes; combine the second soaking solutions and concentrate to 1:2 (crude drug: medicinal solution) to obtain a warm soaking concentrate. Dissolve chitosan with acetic acid solution to make 2% chitosan solution, take 5% chitosan solution of warm soak concentrate, add warm soak concentrate. Leave it overnight, filter by centrifugation, and concentrate under reduced pressure to a relative density of 1.34 to obtain 3560 g of the filtered concentrate. Add 106.8g (3% of filtered concentrated solution) acrylic resin II, add 12% NaOH solution under stirring, adjust to pH 7.2, let stand to gel, and pack in plastic tubes.

Embodiment 3

[0036] Weigh 2000g of ephedra, 3000g of honeysuckle, 2000g of peucedanum, 4000g of Daqingye, 4000g of dandelion, 3000g of pinellia chinensis, 2500g of inula inula, 3000g of chuanxiong, add 8 times the amount of water, soak at 80°C for 50 minutes, and filter; Add 6 times the amount of water, and soak at 80°C for 40 minutes; combine the second soaking solutions and concentrate to 1:2 (crude drug: medicinal solution) to obtain a warm soaking concentrate. Dissolve chitosan with 1% acetic acid solution to prepare 1% chitosan solution, take 20% chitosan solution of the amount of warm soaking concentrated solution, add warm soaking concentrated solution. Leave overnight, filter by centrifugation, and concentrate under reduced pressure to a relative density of 1.34 to obtain 5280 g of the filtered concentrate. Add 422.4g (8% of filtered concentrate) acrylic resin II, add 12% NaOH solution under stirring, adjust to pH 7.2, let stand to gel, and pack in plastic tubes.

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Abstract

The present invention pertains to the art of medicine, in particular to a compound for curing asthmatic bronchitis and bronchial asthma. The compound is made from the following raw materials: 1 to 5 portions of Chinese ephedra, 3 to 7 portions of honeysuckle, 1 to 5 portions of hogfennel root, 5 to 9 portions of dyer woad leaf, 5-9 portions of dandelion, 3 to 7 portions of prepared pinellia tuber, 2 to 6 portions of inula flower and 3 to 7 portions of chuanxikong rhizme. The present invention also relates to a gel preparation method of the compound, including (1) the crude drugs are taken in proportion, added with water and undergone moving warm extract for twice, and the drug liquid is condensed, thus obtaining the warm concentrated solution; (2) 5 to 20 percent chitosan solution is added into the warm concentrated solution, placed overnight, eccentrified and filtered, decompressed and condensed to the relative density 1.34, thus obtaining the chitosan solution; (3) 3 to 8 percent crylic acidresin II is added into the chitosan solution, stirred for adjusting pH to 7.2, placed for gelation and subpackaged.

Description

Technical field [0001] The invention is a pharmaceutical field, which involves a composition that treats asthma bronchitis and bronchial asthma; it also involves the method of gel agent preparation of the composition. Background technique [0002] According to the relevant chapters of Nelson Pediatric Science (14th Edition), asthma bronchitis, asthma and capillaryitis are collectively called asthma syndrome.The three diseases are collectively referred to as the similarity of their clinical manifestations in many aspects, that is, difficulty breathing, cough, and hypoxia.Global asthma prevention and treatment guidelines (GINA) clearly stated that asthma bronchitis is asthma, that is, asthma induced by infectious causes, the difference between the two lies in the cause of the attack.However, clinically, we can often see that asthma bronchitis is often due to non -infectious causes.Infection, especially viral respiratory infections, is a common cause of asthma attacks. [0003] In 2...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8888A61K9/00A61K47/36A61K47/34A61P11/06A61K47/32
Inventor 胡惠平
Owner HANGZHOU ZHONGMEI HUADONG PHARMA
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