Agrimony total flavone extract, preparing method and applications thereof

Abstract

The invention discloses an extract of agrimony total flavonoids and an extraction and preparation method thereof; the total amount of ketosteroid compounds accounts for 25 percent to 100 percent of the total extraction matter. The invention takes agrimony as raw material and organic solvent whether containing or not containing water as extraction solvent. The extraction procedure is as following: extracting, leaching with solvent and adsorbing resin column to make purification process or using inorganic acid to regulate the PH value of concentrated solution to be no higher than 3, and then obtaining the extraction matter of agrimony after processing. Experiments prove that the extraction matter of agrimony total flavonoids has functions of antioxidation, anti-myocardial ischemia and reducing blood lipid. The extraction matter of agrimony total flavonoids can be used as food preservative and health product additive; the extraction matter of agrimony total flavonoids, carriers acceptable in pharmacy or excipient are made into various pharmaceutical dosage forms for anti-myocardial ischemia and reducing blood lipid. The invention has the advantages of simple technics and good treatment effect and can be widely used for curing or preventing coronary heart disease, hyperlipoidemia, high blood pressure or preventing cardio-cerebrovascular diseases such as atherosclerosis, etc.

Description

Technical field:

[0001] The invention relates to Agrimony total flavonoids extract, a preparation method thereof, and the use of the extract as an antioxidant and in the preparation of cardiovascular and cerebrovascular medicines. Background technique:

[0002] Agrimonia pilosa, also known as deli grass, melon herb, old beef tendon, wolf bud grass, is the aerial part of the perennial herbaceous plant Agrimonia pilosa Ledeb. in the family Rosaceae. Born in hillside forests, roadsides and ditches. Mainly produced in Zhejiang, Jiangsu and Hubei. In traditional Chinese medicine, the main medicinal effects are astringent to stop bleeding, stop malaria, stop dysentery, and detoxify. For hemoptysis, hematemesis, malaria, fatigue, carbuncle.

[0003] There are many research reports on the pharmacological effects of Agrimony water extract. Modern research shows that the water extract of Agrimony has cardiotonic, antihypertensive, hypoglycemic, antibacterial, insecticidal and anti...

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