79 results about "Arterial flow" patented technology

A noninvasive patient-specific method is provided to aid in the analysis, diagnosis, prediction or treatment of hemodynamics of the cardiovascular system of a patient. Coronary blood flow and pressure can be predicted using a 3-D patient image-based model that is implicitly coupled with a model of at least a portion of the remaining cardiovascular system. The 3-D patient image-based model includes at least a portion of the thoracic aorta and epicardial coronaries of the patient. The shape of one or more velocity profiles at the interface of the models is enforced to control complex flow features of recirculating or retrograde flow thereby minimizing model instabilities and resulting in patient-specific predictions of coronary flow rate and pressure. The invention allows for patient-specific predictions of the effect of different or varying physiological states and hemodynamic benefits of coronary medical interventions, percutaneous coronary interventions and surgical therapies.

The invention discloses a post-arterial paracentesis hemostasis supervision method and related equipment. The method comprises the following steps: monitoring blood flow data of a puncture part of a patient by using a sensor, wherein the blood flow data comprises artery blood flow data and tissue micro blood flow data; based on the pulse blood flow data and the tissue micro blood flow data, the hemostasis effect and the local tissue ischemia condition of the puncture part of the patient are evaluated; and adjusting the hemostasis pressure according to the hemostasis effect and the local tissue ischemia condition. The problems that a traditional manual compression method is time-consuming and labor-consuming, and the hemostatic effect is poor due to misoperation can be solved.

A wearable Doppler blood flowmeter can be used with an inflatable cuff to measure blood flow, such as for assessing peripheral artery disease (PAD). The present approach can include techniques such as providing or using a wearable acoustic Doppler blood flowmeter, without requiring the intricate manipulation of a handheld Doppler probe. The system can select a pair of acoustic transmitter and acoustic receiver from a set of more than two transducers, including one or more of different locations, orientations, or spacings, such as to vary a targeted region. The RF echo response signal can be translated to an audio response signal. An audio response signal injection circuit can adaptively inject a noise or other enhancement signal, such as to help improve perceptibility of an audible characteristic of pulsatile arterial blood flow. A trained machine learning model can be employed to select or adjust operating settings, to assess diagnostic information, or both.

Systems and methods are provided for reducing the reliance on operator skill during vascular ultrasound procedures. The placement of an ultrasound probe to assess perfusion associated with a wound may be facilitated by receiving input suitable for identifying an anatomical region associated with the wound and providing an indication of a suitable initial probe position, and optionally, probe orientation, for acoustically interrogating a target arterial vessel known to provide perfusion to the anatomical region associated with the wound. Regions exhibiting arterial flow may be detected as the probe is moved, enabling arterial vessel detection and localization. A subregion within the detected arterial vessel and a beam steering angle may be autonomously determined for spectral Doppler data collection, enabling the measurement of hemodynamic measures associated with the arterial vessel. Example apparatus for securing the probe to the patient and facilitating probe positioning to search for a target vessel are disclosed.

The invention discloses a spleen artery blood flow limiting stent and a using method, and particularly relates to the technical field of medical instruments.The spleen artery blood flow limiting stent comprises a supporting stent and a flow limiting stent, the supporting stent is arranged outside the flow limiting stent in a sleeving mode, the two ends of the flow limiting stent are fixedly connected with the inner side wall of the supporting stent, and the flow limiting stent is a covered stent; the flow limiting support comprises a contraction section and an expansion section, the contraction section and the expansion section are fixedly connected and communicated, and splenic artery blood flow in the supporting support flows in from the contraction section and flows out from the expansion section. According to the invention, spleen blood perfusion after partial spleen artery embolism operation can be reduced, and recurrence of splenic hyperfunction is reduced.

The utility model discloses a splenic artery blood flow limiting support, and particularly relates to the technical field of medical instruments, the splenic artery blood flow limiting support comprises a supporting support and a flow limiting support, the supporting support is sleeved outside the flow limiting support, two ends of the flow limiting support are fixedly connected with the inner side wall of the supporting support, the flow limiting support is a covered stent, and the flow limiting support comprises a contraction section and an expansion section. The contraction section and the expansion section are fixedly connected and communicated, and splenic artery blood flow in the supporting stent flows in from the contraction section and flows out from the expansion section. The splenic artery embolism postoperative spleen blood perfusion can be reduced, and the recurrence of splenic hyperfunction is reduced.

The embodiments of the present application provide a blood monitoring device and a blood monitoring method for traumatic shock, wherein the device comprises: a first detection module, configured to obtain a common carotid artery velocity time integral and a heart rate by detecting carotid artery blood flow; a second detection module, configured to obtain a blood oxygen saturation by detecting the blood oxygen status of the arterial blood flow; a processing module, configured to determine a carotid artery oxygen delivery reflecting the oxygen supply capacity of the carotid artery to the head according to the common carotid artery velocity time integral, the heart rate, the blood oxygen saturation, the common carotid artery area and the hemoglobin value in the blood; in this way, the detection of multiple parameters is achieved, and it is beneficial to quickly obtain the status and changes of the patient's brain oxygen supply and systemic oxygen supply, comprehensively consider the patient's compensatory capacity, thereby judging the patient's overall risk and reducing the probability of the patient suffering from hemorrhagic shock.

The application provides a method for measuring an ultrasound coronary artery flow reserve fraction, and relates to the technical field of ultrasound imaging.The method for measuring the ultrasound coronary artery flow reserve fraction provided by the application estimates the blood pressure distribution of a coronary artery stenosis region through a fluid mechanics model based on ultrasound contrast video, and then obtains a flow reserve fraction FFRUS and a reliability index sigma.Based on the ultrasound contrast video data V0 collected, the coronary artery ultrasound contrast imaging video data V1 is determined by using a sliding window double filtering strategy;based on V1, the stenosis region of the coronary artery is determined as a target region Omega;based on V1, the blood flow velocity field V2 of the target region Omega is determined;based on V2 and the proximal blood pressure value Pa of the target region Omega, the blood pressure distribution V3 of the target region Omega is determined;based on V3, the flow reserve fraction FFRUS and the reliability index sigma are calculated by using the flow reserve fraction definition.

The application provides a recyclable arterial blood flow reduction device, relates to the technical field of interventional medical instruments, and comprises a stent part, a recycling part and a pushing assembly. The stent part comprises a stent body which is wide in the middle and narrow at both ends, and a proximal rod body connected to the proximal end of the stent body. The recycling part comprises a recycling hook connected to the proximal rod body, and a recess is arranged on the side wall of the recycling hook. The pushing assembly comprises a long sheath tube, a sleeve loop catheter slidingly arranged on the long sheath tube, and a clamping piece arranged on the sleeve loop catheter. After the sleeve loop catheter is sleeved on the recycling hook, the clamping piece is connected with the recess, and the sleeve loop catheter is pulled out to take out the blood flow reduction device. The metal elastic sheet is arranged, after the sleeve loop catheter is sleeved on the recycling hook, the recess and the clamping piece are connected together at least in the axial direction, the stent body is moved to the proximal end by pulling the sleeve loop catheter, and the problem that the stent body is difficult to be connected again and the blood flow reduction device is difficult to be taken out is conveniently solved.

Venous and arterial flow systems for patient simulators, invasive blood pressure systems for patient simulators, tension pneumothorax inserts for patient simulators, and ultrasound-guided procedure inserts for patient simulators, as well as associated devices, systems, and methods, are provided.

The invention provides an arterial flow limiter. The arterial flow limiter comprises a fixing support used for anchoring the flow limiter to an artery; the flow adjusting support is used for adjusting blood flow; the connecting part is used for connecting the fixed bracket and the flow adjusting bracket; the fixing support allows blood to pass through holes of the fixing support, and the mesh density of the fixing support is smaller than that of the flow adjusting support, so that after the blood flows through the fixing support, most of the blood flows through a gap between the flow adjusting support and an artery wall; the expansion degree of the flow adjusting support can be adjusted, the outer surface of the flow adjusting support is of a streamline structure, the curvature radius Rc of the outer contour is matched with the diameter D of the artery, and Rc / D = 0.25 is met, so that the wall surface shearing force of blood flow to the artery is stabilized within a certain range, and turbulent flow is prevented from being formed.

The invention relates to a coronary microcirculation disturbance examination technology in non-occlusive coronary diseases, and aims to objectively evaluate the myocardial ischemia degree of angina pectoris patients without occlusive coronary diseases and quantify the myocardial ischemia range caused by microcirculation disturbance through a load dynamic myocardial perfusion imaging (MPI) technology. Siemens third-generation double-source CT is adopted, a coarse pitch scanning mode is utilized, a one-stop CCTA combined MPI technology is achieved, the problem that the radiation dosage is too high is solved, and meanwhile the detection rate of myocardial ischemia is increased. Indexes such as myocardial blood flow (MBF), myocardial blood volume (MBV), time of arrival (TTP), coronary artery blood flow reserve (CFR) and the like of angina pectoris patients and healthy volunteers are compared, and changes of myocardial ischemia areas are objectively evaluated. The degree and range of microcirculation disturbance are quantitatively evaluated, and an infarction region and an ischemic region are identified. Quantitative evaluation is carried out on coronary artery microcirculation of the angina pectoris patient in clinical work, and a basis is provided for early intervention.

The present invention, in some embodiments thereof, relates to methods and / or apparatus for measuring the effectiveness of a renal denervation treatment. In some embodiments, a method for determining effectiveness of the denervation treatment comprises tracking at least one of arterial wall movement, arterial blood flow rate, arterial blood flow velocity, blood pressure and arterial diameter at one or more selected locations in the renal artery over time, and assessing the effectiveness of said renal denervation treatment according to results obtained by tracking.

Systems and methods are provided for reducing the reliance on operator skill during vascular ultrasound procedures. The placement of an ultrasound probe to assess perfusion associated with a wound may be facilitated by receiving input suitable for identifying an anatomical region associated with the wound and providing an indication of a suitable initial probe position, and optionally, probe orientation, for acoustically interrogating a target arterial vessel known to provide perfusion to the anatomical region associated with the wound. Regions exhibiting arterial flow may be detected as the probe is moved, enabling arterial vessel detection and localization. A subregion within the detected arterial vessel and a beam steering angle may be autonomously determined for spectral Doppler data collection, enabling the measurement of hemodynamic measures associated with the arterial vessel. Example apparatus for securing the probe to the patient and facilitating probe positioning to search for a target vessel are disclosed.

A radial artery blood flow monitoring device relates to the technical field of cardiovascular medicine. The radial artery blood flow monitoring device is based on a radial artery air bag compressor, an air bag is installed on the lower surface of the radial artery air bag compressor, the radial artery blood flow monitoring device comprises an air pump, a blood flow monitoring probe and a signal processor, the air pump is communicated with the air bag through an air supply pipe, and the blood flow monitoring probe is of an inverted-Y-shaped structure; the blood flow monitoring probes are embedded in the two sides of the radial artery air bag compressor, a first B-ultrasonic probe is arranged on one side of the lower end of each blood flow monitoring probe, a second B-ultrasonic probe is arranged on the other side of the lower end of each blood flow monitoring probe, one B-ultrasonic probe is used for monitoring the blood flow condition of the proximal end, and the other B-ultrasonic probe is used for monitoring the blood flow condition of the telecentric end. The upper end of the blood flow monitoring probe is connected with the signal processor through a wire. According to the scheme, the problems that in the operation process of an existing pneumatic compression device, the hemostasis pressure needs to be frequently evaluated and adjusted, the workload of nursing staff is large, and use and popularization are inconvenient are solved.

The invention discloses a pneumatic pressurization control method and system for an electronic sphygmomanometer and a related device, which are used for improving the comfort of a tested person and the measurement safety and improving the measurement efficiency of a blood pressure measurement process on the whole. The method comprises the following steps: carrying out component separation on a photoelectric volume pulse wave signal to obtain a pulsation component reflecting the periodic change of arterial blood flow, and constructing an amplitude feature sequence updated along with a pressurization process; calculating the attenuation rate of the amplitude feature sequence relative to the reference sequence in the current pressure interval; constructing a nonlinear response trend model of the pulse amplitude to the pressurization process; whether the far-end artery blood flow enters a blocking critical state or not is judged in combination with a preset background noise base; if yes, the cuff is controlled to stop continuous pressurization, and the self-adaptive pressurization upper limit parameter measured this time is determined according to the cuff pressure at the corresponding moment; and controlling the sphygmomanometer to be switched from the pressurization control process to the deflation measurement process based on the self-adaptive pressurization upper limit parameter.

The present invention relates to the field of ultrasounds and imagining of the coronary blood flow of the heart. Patients with coronary microvascular dysfunction (CMD) have poor prognostic with significantly higher rates of cardiovascular events, including hospitalization for heart failure, sudden cardiac death, and myocardial infarction (MI). Despite the urgent clinical need, there are no non-ionizing and non-invasive techniques available in clinic to directly visualize the coronary microvasculature and assess the local coronary microvascular system. Flow imaging remains a difficult task to perform in the heart because of the fast movements of this organ. In order to overcome the limitations of actual imaging methods for the coronary blood flow, the inventors proposed an ultrasound ultrafast imaging method that automatically detect the time periods in which the myocardium velocity is low and estimate the coronary flow velocity and the tissue velocity from the same data acquisition.

To provide an erection assisting device for the male genitalia, which induces an erection by causing a large amount of arterial blood to flow into the corpus cavernosum of the penis from a relaxed state, filling it with blood, and maintains the erect state by making it difficult for the blood in the penis to flow out of the penis. [Solution] The male erection assistance device 4 is comprised of a ring 1 to be attached to the base of the scrotum A, a ring 2 to be attached to the base of the penis B, and a joint 3 for holding the rings 1 and 2 at an angle rather than parallel to each other.

The invention provides a method for measuring ultrasonic fractional flow reserve of coronary artery, and relates to the technical field of ultrasonic imaging. According to the method for measuring the ultrasonic fractional flow reserve of the coronary artery, the blood pressure distribution of the narrow area of the coronary artery is obtained through estimation of the fluid mechanics model on the basis of the ultrasonic contrast video, and then the fractional flow reserve FFRUS and the credibility index sigma are obtained. Based on the acquired ultrasound contrast video data V0, determining the ultrasound contrast video data V0 as coronary artery ultrasound contrast imaging video data V1 by using a sliding window dual filtering strategy; based on V1, determining a narrow area of the coronary artery as a target area omega; based on V1, determining a blood flow velocity field V2 of the target area omega; determining the blood pressure distribution V3 of the target area omega based on the V2 and the near-end blood pressure value Pa of the target area omega; and on the basis of the V3, the fractional flow reserve FFRUS and the credibility index sigma are obtained through calculation by utilizing fractional flow reserve definition.

The food additive lauryl gallate (LG, E312) is a molecule with antioxidant and hydrophobic properties which has also been shown to exert antibacterial, antiviral and anti-tumoral effects. Here, the inventors show that LG at a low concentration has the ability to spontaneously induce washed human platelet shape change, filopodia emission, granule secretion, phosphatidylserine expression and aggregation. LG was able to activate intracellular signaling pathways including Akt, p38MAP-kinase and calcium response and to trigger activation of the αIIbβ3 integrin. LG also significantly potentiated platelet aggregation induced by low doses of collagen or thrombin receptor agonist peptide. Consistent with this, low doses of LG added to human blood promoted a strong platelet thrombotic response under arterial flow on a collagen matrix. As shown by electron microscopy, at a high concentration, LG induced a dramatic platelet membrane modification associated with calcium influx and a slow platelet aggregation response. Finally, a local flash-application of LG efficiently decreased the tail bleeding in rats suggesting that this compound has the potential to act as a hemostatic. Overall, the results indicate that the food additive LG, possibly through its capacity to modify membrane lateral organization, has pro-aggregant and antihemorrhagic properties.

The invention provides a myocardial coronary artery blood perfusion space-time dynamic evolution imaging system, and relates to the technical field of biomedical imaging, the method comprises the following steps: a connection layer receives a frame data stream containing an original speckle image sent by a user interface layer, and sends the frame data stream to a data processing layer; after the data processing layer receives the frame data stream, the frame data stream is subjected to parallel processing in a video recording unit and a frame analysis unit, and a blood flow index corresponding to each pixel in the original speckle image is obtained; and the connection layer generates a blood flow index distribution diagram based on the received blood flow index corresponding to each pixel in the original speckle image sent by the data processing layer in the first buffer area of the blood flow index diagram conversion unit, and sends the blood flow index distribution diagram to the user interface layer for display. According to the imaging system provided by the invention, the spatial-temporal dynamic evolution process of myocardial coronary blood flow can be observed in real time, the spatial-temporal resolution is very high, and an important index is provided for quality evaluation in coronary artery bypass grafting.

A system for monitoring blood distribution in a subject, the system comprising a processor (38) responsive to Doppler ultrasound data representing arterial blood flow in at least two different locations of the subject, such as the neck and arm, to obtain velocity (C, B1, B2, B3) or volume flow at each location, to monitor changes in a predetermined function of blood flow, and to provide an output indicative of monitored changes that may be due to blood volume centralization. This may indicate the onset of hypovolemia or hypervolemia.

The invention relates to a real-time recognition device for spontaneous circulation recovery during cardio-pulmonary resuscitation. The real-time identification equipment comprises a signal sensing device which comprises an ultrasonic probe and is used for sensing a carotid artery blood flow signal in real time by adopting the ultrasonic probe; and the real-time analysis device is used for analyzing the carotid artery blood flow signal by utilizing a pre-trained machine learning model so as to identify the spontaneous circulation recovery during the cardio-pulmonary resuscitation period in real time. According to the embodiment of the invention, real-time, accurate and non-invasive ROSC identification can be realized.

The present invention relates to determining a flow profile in an artery from ultrasound imaging data. To this end, a computer-implemented method is provided for determining a flow profile based on arterial measurements, intra-arterial velocities, and asymmetry measures, the arterial measurements, intra-arterial velocities, and asymmetry measures determined from ultrasound imaging data, including B-mode, pulsed wave Doppler, and color or power Doppler ultrasound imaging data.

The invention discloses a bifurcated aneurysm stent which is of a self-expanding structure, at least one window is formed in the wall of the stent, and the window can be automatically opened after the stent is released from a micro catheter by means of the hyperelasticity of nickel-titanium alloy, so that the neck of the bifurcated aneurysm is covered. By means of the design, the embolism effect is guaranteed, meanwhile, the influence of the stent on lateral artery blood flow is remarkably weakened, and the risk that a traditional stent shields branch arteries is avoided. The intravascular metal content and the thrombus occurrence rate are effectively reduced, the wide-neck aneurysm treatment problem is solved, and the beneficial effects of being easy and convenient to operate, high in safety and capable of accelerating healing are achieved.

The present invention discloses a method, system, device, and medium for determining the fractional flow reserve (FFR) of a coronary artery. This method uses a fully connected network model to build a network model for determining the FFR distal to a stenosis. The model extracts the geometric features of the blood vessels from acquired IVUS or IVOCT image sequences and calculates the pressure loss across the stenosis. The geometric feature parameter set of the target vessel segment and the calculated pressure loss across the stenosis are input into the trained network model, which then outputs the FFR distal to the stenosis of the target vessel segment. The method utilizes deep learning technology, combining data-driven analysis with physical knowledge to integrate coronary artery physiology and morphology, thereby improving the accuracy of physiological assessments of coronary artery lesions.

The invention discloses a conduit pump clamping device and an in-vitro simulation circulating system, the conduit pump clamping device comprises an inlet flange and an outlet flange, and fluid flows from the inlet flange to the outlet flange. A penetrating pipe is arranged in the outlet flange, one end of the penetrating pipe communicates with the first cavity, and the other end of the penetrating pipe penetrates through the side wall of the outlet flange and extends out of the outlet flange. The far end of the catheter pump can penetrate into the catheter pump clamping device through the penetrating pipe until the fluid inlet in the catheter pump is located in the first cavity, and the fluid outlet in the catheter pump is located in the penetrating pipe. At the moment, the fluid entering the outlet flange can flow out in two ways: the fluid is pumped out through the conduit pump or flows out from a fluid outlet on the outlet flange. In this way, the pumping flow of the conduit pump in the auxiliary process can be obtained by measuring the fluid flow of the penetrating pipe; and the fluid can be converged after flowing out, and the total flow of the artery can be obtained by measuring the converged flow, so that a tester can evaluate the real performance of the catheter pump.

A method for medical examination, in particular determination of the blood pressure of an animal that preferably has a paw and is in particular an animal of the subfamily of the Felinae. In the method, a curve comprising information about the arterial blood flow of the animal, in particular a photoplethysmogram, is recorded, and the curve is cut into several curve sections in such a way that each curve section corresponds to a heartbeat. According to another independent aspect, a sensor or a subset of sensors is selected from several sensors of the same kind to perform the examination.

The present disclosure describes a system that can enable the prediction of coronary flow without invasive medical procedure. The system can generate physical models that can provide an accurate assessment of coronary mechanics and enable realistic simulation of coronary procedures. The models can enable the hemodynamic measurement of flow through the model and the study of flow dynamics through the model and the biomechanics of the model.

Methods and systems are provided for diagnosis and / or treatment of microvascular dysfunction, such as microvascular obstruction (MVO) by injecting volumetric flows into a vessel using an infusion system to arrest or reverse native antegrade flow, such that an equipoise value of volumetric flow rate and corresponding pressure may be determined, which in turn enables calculation of MVO, absolute hydrodynamic resistance, fractional flow reserve, coronary flow reserve, and other physiologic parameters in real-time or near real time.